Crystal structure of an integron gene cassette-associated protein from Vibrio cholerae identifies a cationic drug-binding module

PLoS ONE

Volumn 6, Issue 3, 2011, Pages

  Deshpande, Chandrika N ^a   Harrop, Stephen J ^b,c   Boucher, Yan ^d,g   Hassan, Karl A ^a   Leo, Rosa Di ^e   Xu, Xiaohui ^e   Cui, Hong ^e   Savchenko, Alexei ^e   Chang, Changsoo ^e   Labbate, Maurizio ^f   Paulsen, Ian T ^a   Stokes, H W ^f   Curmi, Paul M G ^b,c   Mabbutt, Bridget C ^a  

^a MACQUARIE UNIVERSITY   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c St Vincent's Centre for Applied Medical Research   (Australia)

^d Massachusetts Institute of Technology   (United States)

^e UNIVERSITY OF TORONTO   (Canada)

^f UNIVERSITY OF TECHNOLOGY SYDNEY   (Australia)

^g UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ARAC PROTEIN; BACTERIAL PROTEIN; GLUTAMIC ACID; MACROGOL; CATION; DRUG; LIGAND;

ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BINDING AFFINITY; CATION EXCHANGE; CONTROLLED STUDY; CRYSTAL STRUCTURE; FLUORESCENCE ANALYSIS; GENE CASSETTE; GENE IDENTIFICATION; GENE SEQUENCE; GENE TRANSFER; HYDROPHOBICITY; INTEGRON; LIGAND BINDING; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN INTERACTION; SEQUENCE ANALYSIS; STRUCTURAL HOMOLOGY; STRUCTURE ANALYSIS; TRANSCRIPTION REGULATION; VIBRIO CHOLERAE; AMINO ACID SEQUENCE; CHEMISTRY; GENETICS; METABOLISM; MOLECULAR GENETICS; PHYLOGENY; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT; X RAY CRYSTALLOGRAPHY;

VIBRIO; VIBRIO CHOLERAE;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CATIONS; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; GENES, BACTERIAL; INTEGRONS; LIGANDS; MOLECULAR SEQUENCE DATA; PHARMACEUTICAL PREPARATIONS; PHYLOGENY; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; STRUCTURAL HOMOLOGY, PROTEIN; VIBRIO CHOLERAE;

EID: 79952301995     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0016934     Document Type: Article

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