The Structural Mechanism for Transcription Activation by MerR Family Member Multidrug Transporter Activation, N Terminus

Journal of Biological Chemistry

Volumn 279, Issue 19, 2004, Pages 20356-20362

  Newberry, Kate J ^a   Brennan, Richard G ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; CONFORMATIONS; CRYSTAL STRUCTURE; DNA; GENES;

PROMOTERS; TRANSCRIPTION ACTIVATION; TRANSCRIPTION REGULATORS;

BIOCHEMISTRY;

ADENINE; DNA; GLYCOPROTEIN P; MERR PROTEIN; PROTEIN BMRR; PROTEIN CUER; PROTEIN MTAN; PROTEIN ZNTR; REGULATOR PROTEIN; SPACER DNA; TETRAPHENYLPHOSPHONIUM; THYMIDINE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BASE PAIRING; BINDING AFFINITY; CONFORMATION; CRYSTAL STRUCTURE; GENE ACTIVATION; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA INTERACTION; PROTEIN FAMILY; PROTEIN STRUCTURE; STRESS; TRANSCRIPTION INITIATION;

BACTERIAL PROTEINS; BASE SEQUENCE; BIOLOGICAL TRANSPORT; CRYSTALLOGRAPHY, X-RAY; DNA; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, BACTERIAL; DRUG RESISTANCE, MULTIPLE; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS;

EID: 2442452545     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M400960200     Document Type: Article

References (22)

1. Brown, N. L., Stoyanov, J. V., Kidd, S. P., and Hobman, J. L. (2003) FEMS Microbiol. Rev. 27, 145-163
2. Outten, C. E., Outten, F. W., and O'Halloran, T. V. (1999) J. Biol. Chem. 274, 37517-37524
3. Summers, A. O. (1992) J. Bacteriol. 174, 3097-3101
4. Ansari, A. Z., Bradner, J. E., and O'Halloran, T. V. (1995) Nature 374, 371-375
5. Record, J. M. T., Reznikoff, W. S., Craig, M. L., McQuade, K. L., and Schlax, P. J. (1996) in Escherichia coli and Salmonella: Cellular and Molecular Biology (Neidhardt, F. C., ed) Vol. 1, 2nd Ed., pp. 792-821, ASM Press, Washington, D. C.
6. Hellmann, E. E., and Moran, C. P., Jr. (2002) in Bacillus subtilis and Its Closest Relatives: From Genes to Cells (Sonenshein, A. L., Hoch, J. A., and Losick, R., ed), pp. 289-312, ASM Press, Washington, D. C.
7. Heldwein, E. E., and Brennan, R. G. (2001) Nature 409, 378-382
8. Baranova, N. N., Danchin, A., and Neyfakh, A. A. (1999) Mol. Microbiol. 31, 1549-1559
9. Godsey, M. H., Baranova, N. N., Neyfakh, A. A., and Brennan, R. G. (2001) J. Biol. Chem. 276, 47178-47184
10. Godsey, M. H., Baranova, N. N., Neyfakh, A. A., and Brennan, R. G. (2000) Acta Crystallogr. D Biol. Crystallogr. 56, 1456-1458
11. Terwilliger, T. C., and Berendzen, J. (1999) Acta Crystallogr. D Biol. Crystallogr. 55, 849-861
12. Brunger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T., and Warren, G. L. (1998) Acta Crystallogr. D Biol. Crystallog. 54, 905-921
13. Jones, T. A., Zou, J. Y., Cowan, S. W., and Kjeldgaard, M. (1991) Acta Crystallogr. A 47, 110-119
14. Brunger, A. T. (1997) Methods Enzymol. 277B, 366-396
15. Guex, N., and Peitsch, M. C. (1997) Electrophoresis 18, 2714-2723
16. Kissinger, C. R., Gehlhaar, D. K., and Fogel, D. B. (1999) Acta Crystallogr. Sec. D 55, 484-491
17. Laskowski, R. A., Moss, D. S., and Thornton, J. M. (1993) J. Mol. Biol. 231, 1049-1067
18. Huffman, J. L., and Brennan, R. G. (2002) Curr. Opin. Struct. Biol. 12, 98-106
19. Gajiwala, K. S., and Burley, S. K. (2000) Curr. Opin. Struct. Biol. 10, 110-116
20. Changela, A., Chen, K., Xue, Y., Holschen, J., Outten, C. E., O'Halloran, T. V., and Mondragon, A. (2003) Science 301, 1383-1387
21. Lavery, R., and Sklenar, H. (1989) J. Biomol. Struct. Dyn. 6, 655-667
22. Brocklehurst, K. R., Hobman, J. L., Lawley, B., Blank, L., Marshall, S. J., Brown, N. L., and Morby, A. P. (1999) Mol. Microbiol. 31, 893-902