Structural basis for antibiotic recognition by the TipA class of multidrug-resistance transcriptional regulators

EMBO Journal

Volumn 22, Issue 8, 2003, Pages 1824-1834

  Kahmann, Jan D ^a   Sass, Hans Jürgen ^a   Allan, Martin G ^a   Seto, Haruo ^b   Thompson, Charles J ^a   Grzesiek, Stephan ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b TOKYO UNIVERSITY OF AGRICULTURE   (Japan)

Author keywords

Antibiotic recognition; Globin fold; Heteronuclear NMR; Protein dynamics; Transcriptional regulation

Indexed keywords

ANTIBIOTIC AGENT; BACTERIAL PROTEIN; BERNINAMYCIN; GENINTIOCIN; HEME; HEMOGLOBIN; NOSIHEPTIDE; PROMOTHIOCIN; PYRROLE DERIVATIVE; THIOACTIN; THIOSTREPTON; THIOTIPIN; THIOXAMYCIN; TIPAL PROTEIN; TIPAS PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BACILLUS SUBTILIS; CARBOXY TERMINAL SEQUENCE; DRUG BINDING; LIGAND BINDING; MULTIDRUG RESISTANCE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN STRUCTURE; THREE DIMENSIONAL IMAGING; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BINDING SITES; DRUG RESISTANCE, MULTIPLE; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; STRUCTURE-ACTIVITY RELATIONSHIP; TRANS-ACTIVATORS;

BACILLUS SUBTILIS; BACTERIA (MICROORGANISMS); POSIBACTERIA; PTEROGYNE NITENS;

EID: 0037447301     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg181     Document Type: Article

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