The complex that inserts lipopolysaccharide into the bacterial outer membrane forms a two-protein plug-and-barrel

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 6, 2011, Pages 2486-2491

  Freinkman, Elizaveta ^a   Chng, Shu Sin ^b   Kahne, Daniel ^a,b,c  

^a HARVARD UNIVERSITY   (United States)

^b HARVARD UNIVERSITY   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Lipopolysaccharide assembly; Outer membrane protein complex

Indexed keywords

BACTERIAL PROTEIN; LIPOPOLYSACCHARIDE; LPTD PROTEIN; LPTE PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL OUTER MEMBRANE; BETA SHEET; BILAYER MEMBRANE; BIOGENESIS; COMPLEX FORMATION; CONTROLLED STUDY; CYTOPLASM; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION;

BACTERIAL OUTER MEMBRANE PROTEINS; BIOLOGICAL TRANSPORT; CELL MEMBRANE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; LIPOPOLYSACCHARIDES; MICROBIAL VIABILITY; MODELS, MOLECULAR; PERIPLASM; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY;

BACTERIA (MICROORGANISMS); NEGIBACTERIA;

EID: 79952289193     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1015617108     Document Type: Article

References (40)

1. Kamio Y, Nikaido H (1976) Outer membrane of Salmonella typhimurium: Accessibility of phospholipid headgroups to phospholipase C and cyanogen bromide activated dextran in the external medium. Biochemistry 15:2561-2570.
2. Funahara Y, Nikaido H (1980) Asymmetric localization of lipopolysaccharides on the outer membrane of Salmonella typhimurium. J Bacteriol 141:1463-1465. (Pubitemid 10074786)
3. Mühlradt PF, Golecki JR (1975) Asymmetrical distribution and artefactual reorientation of lipopolysaccharide in the outer membrane bilayer of Salmonella typhimurium. Eur J Biochem 51:343-352.
4. Nikaido H (2003) Molecular basis of bacterial outer membrane permeability revisited. Microbiol Mol Biol Rev 67:593-656.
5. Raetz CRH, Whitfield C (2002) Lipopolysaccharide endotoxins. Annu Rev Biochem 71:635-700. (Pubitemid 34800232)
6. Chng SS, Gronenberg LS, Kahne D (2010) Proteins required for lipopolysaccharide assembly in Escherichia coliform a transenvelope complex. Biochemistry 49:4565-4567.
7. Sperandeo P, Dehò G, Polissi A (2009) The lipopolysaccharide transport system of Gram-negative bacteria. Biochim Biophys Acta 1791:594-602.
8. Braun M, Silhavy TJ (2002) Imp/OstA is required for cell envelope biogenesis in Escherichia coli. Mol Microbiol 45:1289-1302. (Pubitemid 35015353)
9. Wu T, et al. (2006) Identification of a protein complex that assembles lipopolysaccharide in the outer membrane of Escherichia coli. Proc Natl Acad Sci USA 103:11754-11759. (Pubitemid 44182523)
10. Chng SS, Ruiz N, Chimalakonda G, Silhavy TJ, Kahne D (2010) Characterization of the two-protein complex in Escherichia coliresponsible for lipopolysaccharide assembly at the outer membrane. Proc Natl Acad Sci USA 107:5363-5368.
11. Ruiz N, Chng SS, Hiniker A, Kahne D, Silhavy TJ (2010) Non-consecutive disulfide bond formation in an essential integral outer membrane protein. Proc Natl Acad Sci USA 107:12245-12250.
12. Srinivas N, et al. (2010) Peptidomimetic antibiotics target outer-membrane biogenesis in Pseudomonas aeruginosa. Science 327:1010-1013.
13. Chin JW, Schultz PG (2002) In vivo photocrosslinking with unnatural amino acid mutagenesis. ChemBioChem 3:1135-7.
14. Ryu Y, Schultz PG (2006) Efficient incorporation of unnatural amino acids into proteins in Escherichia coli. Nat Methods 3:263-265.
15. Takase I, et al. (1987) Genes encoding two lipoproteins in the leuS-dacA region of the Escherichia colichromosome. J Bacteriol 169:5692-5699. (Pubitemid 18017858)
16. Bagos PG, Liakopoulos TD, Spyropoulos IC, Hamodrakas SJ (2004) PRED-TMBB: A web server for predicting the topology of beta-barrel outer membrane proteins. Nucleic Acids Res 32:W400-4.
17. Bagos PG, Liakopoulos TD, Spyropoulos IC, Hamodrakas SJ (2004) A hidden Markov model method, capable of predicting and discriminating beta-barrel outer membrane proteins. BMC Bioinformatics 5:29-41.
18. Guedin S, et al. (2000) Novel topological features of FhaC, the outer membrane transporter involved in the secretion of the Bordetella pertussisfilamentous hemagglutinin. J Biol Chem 275:30202-30210.
19. Wimley WC (2003) The versatile β-barrel membrane protein. Curr Opin Struct Biol 13:404-411.
20. Raetz CRH, Reynolds CM, Trent SM, Bishop RE (2007) Lipid A modification systems in Gram-negative bacteria. Annu Rev Biochem 76:295-329.
21. Schirmer T, Keller TA, Wang YF, Rosenbusch JP (1995) Structural basis for sugar translocation through maltoporin channels at 3.1 Å resolution. Science 267:512-514.
22. van den Berg B (2010) Going forward laterally: Transmembrane passage of hydrophobic molecules through protein channel walls. ChemBioChem 11:1339-1343.
23. Hearn EM, Patel DR, Lepore BW, Indic M, van den Berg B (2009) Transmembrane passage of hydrophobic compounds through a protein channel wall. Nature 458:367-379.
24. Hong H, Patel DR, Tamm LK, van den Berg B (2006) The outer membrane protein OmpW forms an eight-stranded β-barrel with a hydrophobic channel. J Biol Chem 281:7568-7577.
25. Neher TM, Lueking DR (2009) Pseudomonas fluorescens ompW: Plasmid localization and requirement for naphthalene uptake. Can J Microbiol 55:553-563.
26. Touw DS, Patel DR, van den Berg B (2010) The crystal structure of OprG from Pseudomonas aeruginosa, a potential channel for transport of hydrophobic molecules across the outer membrane. PLoS ONE 5:e15016.
27. Bishop RE (2005) The lipid A palmitoyltransferase PagP: Molecular mechanisms and role in bacterial pathogenesis. Mol Microbiol 57:900-912.
28. Sutcliffe IC (2010) A phylum level perspective on bacterial cell envelope architecture. Trends Microbiol 18:464-470.
29. Im YJ, Raychaudhuri S, Prinz WA, Hurley JH (2005) Structural mechanism for sensing and transport by OSBP-related proteins. Nature 437:154-158. (Pubitemid 41613443)
30. Huang Y, Smith BS, Chen LX, Baxter RHG, Deisenhofer J (2009) Insights into pilus assembly and secretion from the structure and functional characterization of usher PapC. Proc Natl Acad Sci USA 106:7403-7407.
31. Noinaj N, Guillier M, Barnard TJ, Buchanan SK (2010) TonB-dependent transporters: Regulation, structure, and function. Annu Rev Microbiol 64:43-60.
32. Chimalakonda G, et al. (January 21, 2011) Lipoprotein LptE is required for the assembly of LptD by the β-barrel assembly machine in the outer membrane of Escherichia coli. Proc Natl Acad Sci USA 10.1073/pnas.1019089108.
33. Sampson BA, Misra R, Benson SA (1989) Identification and characterization of a new gene of Escherichia coliK-12 involved in outer membrane permeability. Genetics 122:491-501.
34. Voulhoux R, Bos MP, Geurtsen J, Mols M, Tommassen J (2003) Role of a highly conserved bacterial protein in outer membrane protein assembly. Science 299:262-265. (Pubitemid 36125214)
35. Wu T, et al. (2005) Identification of a multi-component complex required for outer membrane biogenesis in Escherichia coli. Cell 121:235-245. (Pubitemid 40546391)
36. Malinverni JC, et al. (2006) YfiO stabilizes the YaeT complex and is essential for outer membrane protein assembly in Escherichia coli. Mol Microbiol 61:151-164.
37. Sklar JG, et al. (2007) Lipoprotein SmpA is a component of the YaeT complex that assembles outer membrane proteins in Escherichia coli. Proc Natl Acad Sci USA 104:6400-6405. (Pubitemid 47186106)
38. Kim S, et al. (2007) Structure and function of an essential component of the outer membrane protein assembly machine. Science 317:961-964. (Pubitemid 47301326)
39. Hagan CL, Kim S, Kahne D (2010) Reconstitution of outer membrane protein assembly from purified components. Science 328:890-892.
40. Söding J, Biegert A, Lupas AN (2005) The HHpred interactive server for protein homology detection and structure prediction. Nucleic Acids Res 33:W244-W248. (Pubitemid 44529917)