Impact of smoking on the frequencies of micronuclei and other nuclear abnormalities in exfoliated oral cells: A comparative study with different cigarette types

Mutagenesis

Volumn 26, Issue 2, 2011, Pages 295-301

  Nersesyan, Armen ^a   Muradyan, Rafael ^b   Kundi, Michael ^c   Knasmueller, Siegfried ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b Institute of Fine Organic Chemistry   (Armenia)

^c Medical University of Vienna and Wiener Werkstaette for Suicide Research   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

NICOTINE; TAR;

ADULT; ARTICLE; BINUCLEATE SPORE; BINUCLEUS; BROKEN EGG; CHEEK; CHROMATIN CONDENSATION; CHROMOSOME DAMAGE; CIGARETTE SMOKING; COMPARATIVE STUDY; CONTROLLED STUDY; DNA DAMAGE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; KARYOLYSIS; KARYORRHEXIS; MAJOR CLINICAL STUDY; MALE; MICRONUCLEUS; NORMAL HUMAN; PREVALENCE; PRIORITY JOURNAL; PYKNOSIS;

ADULT; CARCINOGENS; CASE-CONTROL STUDIES; CELL NUCLEUS; HUMANS; MALE; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MIDDLE AGED; MOUTH MUCOSA; NICOTINE; SMOKING;

ANIMALIA; NICOTIANA TABACUM;

EID: 79952285287     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/geq092     Document Type: Article

References (50)

1. IARC (2004) Tobacco Smoke and Involuntary Smoking. World Health Organization, Lyon, France.
2. Husgafvel-Pursiainen, K. (2004) Genotoxicity of environmental tobacco smoke: a review. Mutat. Res., 567, 427-445.
3. Nersesyan, A., Kundi, M., Atefie, K., Schulte-Hermann, R. and Knasmuller, S. (2006) Effect of staining procedures on the results of micronucleus assays with exfoliated oral mucosa cells. Cancer Epidemiol. Biomarkers Prev., 15, 1835-1840.
4. Stich, H. F., Rosin, M. P. and Vallejera, M. O. (1984) Reduction with vitamin A and beta-carotene administration of proportion of micronucleated buccal mucosal cells in Asian betal nut and tobacco chewers. Lancet, 1, 1204-1206.
5. Cairns, J. (1975) Mutation selection and the natural history of cancer. Nature, 255, 197-200.
6. Gallus, S., Altieri, A., Bosetti, C. et al. (2003) Cigarette tar yield and risk of upper digestive tract cancers: case-control studies from Italy and Switzerland. Ann. Oncol., 14, 209-213.
7. Bonassi, S., Neri, M., Lando, C. et al. (2003) Effect of smoking habit on the frequency of micronuclei in human lymphocytes: results from the Human MicroNucleus project. Mutat. Res., 543, 155-166.
8. Thomas, P., Holland, N., Bolognesi, C., Kirsch-Volders, M., Bonassi, S., Zeiger, E., Knasmueller, S. and Fenech, M. (2009) Buccal micronucleus cytome assay. Nat. Protoc., 4, 825-837.
9. Tolbert, P. E., Shy, C. M. and Allen, J. W. (1991) Micronuclei and other nuclear anomalies in buccal smears: a field test in snuff users. Am. J. Epidemiol., 134, 840-850.
10. Tolbert, P. E., Shy, C. M. and Allen, J. W. (1992) Micronuclei and other nuclear anomalies in buccal smears: methods development. Mutat. Res., 271, 69-77.
11. Tomiyama, H., Hashimoto, H., Tanaka, H. et al. (1979-1987) Continuous smoking and progression of arterial stiffening: a prospective study. J. Am. Coll. Cardiol., 55.
12. Sayette, M. A., Martin, C. S., Wertz, J. M., Perrott, M. A. and Peters, A. R. (2005) The effects of alcohol on cigarette craving in heavy smokers and tobacco chippers. Psychol. Addict. Behav., 19, 263-270.
13. Kaneko, M., Eguchi, K., Ohmatsu, H., Kakinuma, R., Naruke, T., Suemasu, K. and Moriyama, N. (1996) Peripheral lung cancer: screening and detection with low-dose spiral CT versus radiography. Radiology, 201, 798-802.
14. Shitara, K., Matsuo, K., Hatooka, S. et al. (2009) Heavy smoking history interacts with chemoradiotherapy for esophageal cancer prognosis: a retrospective study. Cancer Sci., 101, 1001-1006.
15. Paetau, I., Rao, D., Wiley, E. R., Brown, E. D. and Clevidence, B. A. (1999) Carotenoids in human buccal mucosa cells after 4 wk of supplementation with tomato juice or lycopene supplements. Am. J. Clin. Nutr., 70, 490-494.
16. Fenech, M. (2002) Chromosomal biomarkers of genomic instability relevant to cancer. Drug Discov. Today, 7, 1128-1137.
17. Dutra, A., Pak, E., Wincovitch, S., John, K., Poirier, M. C. and Olivero, O. A. (2010) Nuclear bud formation: a novel manifestation of Zidovudine genotoxicity. Cytogenet. Genome Res., 128, 105-110.
18. Shi, Q. and King, R. W. (2005) Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines. Nature, 437, 1038-1042.
19. Thomas, P., Harvey, S., Gruner, T. and Fenech, M. (2008) The buccal cytome and micronucleus frequency is substantially altered in Down's syndrome and normal ageing compared to young healthy controls. Mutat. Res., 638, 37-47.
20. Montero, R., Serrano, L., Davila, V. et al. (2003) Metabolic polymorphisms and the micronucleus frequency in buccal epithelium of adolescents living in an urban environment. Environ. Mol. Mutagen., 42, 216-222.
21. Odio, D. A., Vázquez, R. E. I., Tito, R. J. C. and Andrés, P. I. (2005) Buccoepithelial cytologic lesions in workers exposed to chemical products. [Lesiones citológicas bucoepiteliales en trabajadores expuestos a productos quimicos.]. Rev. Med. Inst. Mex. Seguro. Soc., 43, 221-228.
22. Ergene, S., Celik, A., Cavas, T. and Kaya, F. (2007) Genotoxic biomonitoring study of population residing in pesticide contaminated regions in Goksu Delta: micronucleus, chromosomal aberrations and sister chromatid exchanges. Environ. Int., 33, 877-885.
23. da Silva, A. E., Rados, P. V., da Silva Lauxen, I., Gedoz, L., Villarinho, E. A. and Fontanella, V. (2007) Nuclear changes in tongue epithelial cells following panoramic radiography. Mutat. Res., 632, 121-125.
24. Holland, N., Bolognesi, C., Kirsch-Volders, M., Bonassi, S., Zeiger, E., Knasmueller, S. and Fenech, M. (2008) The micronucleus assay in human buccal cells as a tool for biomonitoring DNA damage: the HUMN project perspective on current status and knowledge gaps. Mutat. Res., 859, 93-108.
25. Ding, Y. S., Zhang, L., Jain, R. B., Jain, N., Wang, R. Y., Ashley, D. L. and Watson, C. H. (2008) Levels of tobacco-specific nitrosamines and polycyclic aromatic hydrocarbons in mainstream smoke from different tobacco varieties. Cancer Epidemiol. Biomarkers Prev., 17, 3366-3371.
26. Hecht, S. S. and Hoffmann, D. (1988) Tobacco-specific nitrosamines, an important group of carcinogens in tobacco and tobacco smoke. Carcinogenesis, 9, 875-884.
27. Trivedi, A. H., Dave, B. J. and Adhvaryu, S. G. (1990) Assessment of genotoxicity of nicotine employing in vitro mammalian test system. Cancer Lett., 54, 89-94.
28. Bishun, N. P., Lloyd, N., Raven, R. W. and Williams, D. C. (1972) The in vitro and in vivo cytogenetic effects of nicotine. Acta Biol. Acad. Sci. Hung., 23, 175-180.
29. Adler, I. D. and Attia, S. M. (2003) Nicotine is not clastogenic at doses of 1 or 2 mg/kg body weight given orally to male mice. Mutat. Res., 542, 139-142.
30. Attia, S. M. (2007) The genotoxic and cytotoxic effects of nicotine in the mouse bone marrow. Mutat. Res., 632, 29-36.
31. Attia, S. M. (2007) Chromosomal composition of micronuclei in mouse bone marrow treated with rifampicin and nicotine, analyzed by multicolor fluorescence in situ hybridization with pancentromeric DNA probe. Toxicology, 235, 112-118.
32. Luck, W. and Nau, H. (1984) Nicotine and cotinine concentrations in serum and milk of nursing smokers. Br. J. Clin. Pharmacol., 18, 9-15.
33. Benowitz, N. L. (1983) The use of biologic fluid samples in assessing tobacco smoke consumption. NIDA Res. Monogr., 48, 6-26.
34. Damaj, M. I., Siu, E. C., Sellers, E. M., Tyndale, R. F. and Martin, B. R. (2007) Inhibition of nicotine metabolism by methoxysalen: pharmacokinetic and pharmacological studies in mice. J. Pharmacol. Exp. Ther., 320, 250-257.
35. Costan, E. and Bara, C. I. (2008) Effects of treatment with different concentrations of nicotine solutions on back-mutated Drosophila melanogaster population. Annals University "Alexandru Ioan Cuza", 9, 71-74.
36. Sobkowiak, R. and Lesicki, A. (2009) Genotoxicity of nicotine in cell culture of Caenorhabditis elegans evaluated by the comet assay. Drug Chem. Toxicol., 32, 252-257.
37. Barros, D. M., Galhardi, F. G., Ribas Ferreira, J. L., Guterres, L. B., Dickel, O., Geracitano, L. A., Izquierdo, I. and Monserrat, J. M. (2007) The benefits and drawbacks of nicotine exposure in the cortex and hippocampus of old rats. Neurotoxicology, 28, 562-568.
38. Liu, Q., Tao, Y. and Zhao, B. (2003) ESR study on scavenging effect of nicotine on free radicals. Appl. Magn. Reson., 24, 105-112.
39. Soto-Otero, R., Mendez-Alvarez, E., Hermida-Ameijeiras, A., Lopez- Real, A. M. and Labandeira-Garcia, J. L. (2002) Effects of (-)-nicotine and (-)-cotinine on 6-hydroxydopamine-induced oxidative stress and neurotoxicity: relevance for Parkinson's disease. Biochem. Pharmacol., 64, 125-135.
40. Obata, T., Aomine, M., Inada, T. and Kinemuchi, H. (2002) Nicotine suppresses 1-methyl-4-phenylpyridinium ion-induced hydroxyl radical generation in rat striatum. Neurosci. Lett., 330, 122-124.
41. Valavanidis, A., Vlachogianni, T. and Fiotakis, K. (2009) Tobacco smoke: involvement of reactive oxygen species and stable free radicals in mechanisms of oxidative damage, carcinogenesis and synergistic effects with other respirable particles. Int. J. Environ. Res. Public Health, 6, 445-462.
42. Murphy, S. E. and Heiblum, R. (1990) Effect of nicotine and tobacco-specific nitrosamines on the metabolism of N'-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by rat oral tissue. Carcinogenesis, 11, 1663-1666. (Pubitemid 20281489)
43. Richter, E. and Tricker, A. R. (1994) Nicotine inhibits the metabolic activation of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1- (3-pyridyl)-1-butanone in rats. Carcinogenesis, 15, 1061-1064.
44. Schuller, H. M., Castonguay, A., Orloff, M. and Rossignol, G. (1991) Modulation of the uptake and metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)- 1-butanone by nicotine in hamster lung. Cancer Res., 51, 2009-2014.
45. Weber, R. P., Coon, J. M. and Triolo, A. J. (1974) Nicotine inhibition of the metabolism of 3,4-benzopyrene, a carcinogen in tobacco smoke. Science, 184, 1081-1083.
46. Chen, J., Higby, R., Tian, D., Tan, D., Johnson, M. D., Xiao, Y., Kellar, K. J., Feng, S. and Shields, P. G. (2008) Toxicological analysis of low-nicotine and nicotine-free cigarettes. Toxicology, 249, 194-203.
47. Lu, Y. and Morimoto, K. (2008) Exposure level to cigarette tar or nicotine is associated with leukocyte DNA damage in male Japanese smokers. Mutagenesis, 23, 451-455.
48. Dhillon,V. S.,Thomas, P. and Fenech,M.(2004)Comparison ofDNAdamage and repair following radiation challenge in buccal cells and lymphocytes using single-cell gel electrophoresis. Int. J. Radiat. Biol., 80, 517-528.
49. Yildiz, D. (2004) Nicotine, its metabolism and an overview of its biological effects. Toxicon, 43, 619-632.
50. Hecht, S. S. (2003) Tobacco carcinogens, their biomarkers and tobacco-induced cancer. Nat. Rev. Cancer, 3, 733-744.