메뉴 건너뛰기




Volumn 96, Issue 3, 2011, Pages 737-745

Impaired regulation of the incretin effect in patients with type 2 diabetes

Author keywords

[No Author keywords available]

Indexed keywords

GASTRIC INHIBITORY POLYPEPTIDE; GLUCAGON LIKE PEPTIDE; HEMOGLOBIN A1C; INCRETIN;

EID: 79952284557     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2010-2435     Document Type: Article
Times cited : (185)

References (35)
  • 1
    • 0021864130 scopus 로고
    • New developments in the incretin concept
    • Creutzfeldt W, Ebert R 1985 New developments in the incretin concept. Diabetologia 28:565-573 (Pubitemid 15017390)
    • (1985) Diabetologia , vol.28 , Issue.8 , pp. 565-573
    • Creutzfeldt, W.1    Ebert, R.2
  • 2
    • 0013990334 scopus 로고
    • Plasma insulin responses to glucose and tolbutamide of normal weight and obese diabetic and nondiabetic subjects
    • Perley M, Kipnis DM 1966 Plasma insulin responses to glucose and tolbutamide of normal weight and obese diabetic and nondiabetic subjects. Diabetes 15:867-874
    • (1966) Diabetes , vol.15 , pp. 867-874
    • Perley, M.1    Kipnis, D.M.2
  • 3
    • 1842855423 scopus 로고    scopus 로고
    • Incretins, insulin secretion and Type 2 diabetes mellitus
    • DOI 10.1007/s00125-004-1342-6
    • Vilsbøll T, Holst JJ 2004 Incretins, insulin secretion and type 2 diabetes mellitus. Diabetologia 47:357-366 (Pubitemid 38491230)
    • (2004) Diabetologia , vol.47 , Issue.3 , pp. 357-366
    • Vilsboll, T.1    Holst, J.J.2
  • 4
    • 35748957503 scopus 로고    scopus 로고
    • The physiology of glucagon-like peptide 1
    • DOI 10.1152/physrev.00034.2006
    • Holst JJ 2007 The physiology of glucagon-like peptide 1. Physiol Rev 87:1409-1439 (Pubitemid 350041474)
    • (2007) Physiological Reviews , vol.87 , Issue.4 , pp. 1409-1439
    • Holst, J.J.1
  • 5
    • 0038121744 scopus 로고    scopus 로고
    • Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects
    • DOI 10.1016/S0167-0115(03)00111-3
    • Vilsbøll T, Krarup T, Madsbad S, Holst JJ 2003 Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects. Regul Pept 114:115-121 (Pubitemid 36773875)
    • (2003) Regulatory Peptides , vol.114 , Issue.2-3 , pp. 115-121
    • Vilsboll, T.1    Krarup, T.2    Madsbad, S.3    Holst, J.J.4
  • 6
    • 0022617246 scopus 로고
    • Reduced incretin effect in Type 2 (non-insulin-dependent) diabetes
    • DOI 10.1007/BF02427280
    • Nauck M, Stöckmann F, Ebert R, Creutzfeldt W 1986 Reduced incretin effect in type 2 (non-insulin-dependent) diabetes. Diabetologia 29:46-52 (Pubitemid 16162741)
    • (1986) Diabetologia , vol.29 , Issue.1 , pp. 46-52
    • Nauck, M.1    Stockmann, F.2    Ebert, R.3    Creutzfeldt, W.4
  • 7
    • 0022461548 scopus 로고
    • Incretin effects of increasing glucose loads in man calculated from venous insulin and C-peptide responses
    • Nauck MA, Homberger E, Siegel EG, Allen RC, Eaton RP, Ebert R, Creutzfeldt W 1986 Incretin effects of increasing glucose loads in man calculated from venous insulin and C-peptide responses. J Clin Endocrinol Metab 63:492-498 (Pubitemid 16035703)
    • (1986) Journal of Clinical Endocrinology and Metabolism , vol.63 , Issue.2 , pp. 492-498
    • Nauck, M.A.1    Homberger, E.2    Siegel, E.G.3
  • 8
    • 0012431804 scopus 로고    scopus 로고
    • Report of the expert committee on the diagnosis and classification of diabetes mellitus
    • Expert Committee on the Diagnosis and Classification of Diabetes Mellitus
    • Expert Committee on the Diagnosis and Classification of Diabetes Mellitus 2003 Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 26(Suppl 1):S5-S20
    • (2003) Diabetes Care , vol.26 , Issue.SUPPL. 1
  • 9
    • 84945061771 scopus 로고
    • A general regression procedure for method transformation. Application of linear regression procedures for method comparison studies in clinical chemistry, part III
    • Bablok W, Passing H, Bender R, Schneider B 1988 A general regression procedure for method transformation. Application of linear regression procedures for method comparison studies in clinical chemistry, part III. J Clin Chem Clin Biochem 26:783-790
    • (1988) J Clin Chem Clin Biochem , vol.26 , pp. 783-790
    • Bablok, W.1    Passing, H.2    Bender, R.3    Schneider, B.4
  • 11
    • 0028281773 scopus 로고
    • Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide I in humans
    • Orskov C, Rabenhøj L, Wettergren A, Kofod H, Holst JJ 1994 Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide I in humans. Diabetes 43:535-539 (Pubitemid 24096293)
    • (1994) Diabetes , vol.43 , Issue.4 , pp. 535-539
    • Orskov, C.1    Rabenhoj, L.2    Wettergren, A.3    Kofod, H.4    Holst, J.J.5
  • 12
    • 0021211623 scopus 로고
    • The heterogeneity of gastric inhibitory polypeptide in porcine and human gastrointestinal mucosa evaluated with five different antisera
    • DOI 10.1016/0167-0115(84)90005-3
    • Krarup T, Holst JJ 1984 The heterogeneity of gastric inhibitory polypeptide in porcine and human gastrointestinal mucosa evaluated with five different antisera. Regul Pept 9:35-46 (Pubitemid 14004800)
    • (1984) Regulatory Peptides , vol.9 , Issue.1-2 , pp. 35-46
    • Krarup, T.1    Holst, J.J.2
  • 13
    • 0018760491 scopus 로고
    • Simultaneous measurements of acetaminophen and salicylate in plasma by lipid chromatography
    • Miceli JN, Aravind MK, Cohen SN, Done AK 1979 Simultaneous measurements of acetaminophen and salicylate in plasma by liquid chromatography. Clin Chem 25:1002-1004 (Pubitemid 9200955)
    • (1979) Clinical Chemistry , vol.25 , Issue.6 , pp. 1002-1004
    • Miceli, J.N.1    Aravind, M.K.2    Cohen, S.N.3    Done, A.K.4
  • 14
    • 0035008133 scopus 로고    scopus 로고
    • Gastric emptying: The validity of the paracetamol absorption test adjusted for individual pharmacokinetics
    • DOI 10.1046/j.1365-2982.2001.00249.x
    • Medhus AW, Lofthus CM, Bredesen J, Husebye E 2001 Gastric emptying: the validity of the paracetamol absorption test adjusted for individual pharmacokinetics. Neurogastroenterol Motil 13:179-185 (Pubitemid 32525669)
    • (2001) Neurogastroenterology and Motility , vol.13 , Issue.3 , pp. 179-185
    • Medhus, A.W.1    Lofthus, C.M.2    Bredesen, J.3    Husebye, E.4
  • 16
    • 0026504160 scopus 로고
    • Estimation of insulin secretion rates from C-peptide levels. Comparison of individual and standard kinetic parameters for C-peptide clearance
    • Van Cauter E, Mestrez F, Sturis J, Polonsky KS 1992 Estimation of insulin secretion rates from C-peptide levels. Comparison of individual and standard kinetic parameters for C-peptide clearance. Diabetes 41:368-377
    • (1992) Diabetes , vol.41 , pp. 368-377
    • Van Cauter, E.1    Mestrez, F.2    Sturis, J.3    Polonsky, K.S.4
  • 17
    • 0034070572 scopus 로고    scopus 로고
    • Validation of methods for measurement of insulin secretion in humans in vivo
    • Kjems LL, Christiansen E, Vølund A, Bergman RN, Madsbad S 2000 Validation of methods for measurement of insulin secretion in humans in vivo. Diabetes 49:580-588 (Pubitemid 30183746)
    • (2000) Diabetes , vol.49 , Issue.4 , pp. 580-588
    • Kjems, L.L.1    Christiansen, E.2    Volund, A.3    Bergman, R.N.4    Madsbad, S.5
  • 18
    • 0034771192 scopus 로고    scopus 로고
    • Quantification of beta-cell function during IVGTT in Type II and non-diabetic subjects: Assessment of insulin secretion by mathematical methods
    • DOI 10.1007/s001250100639
    • Kjems LL, Vølund A, Madsbad S 2001 Quantification of β-cell function during IVGTT in type II and non-diabetic subjects: assessment of insulin secretion by mathematical methods. Diabetologia 44:1339-1348 (Pubitemid 33010513)
    • (2001) Diabetologia , vol.44 , Issue.10 , pp. 1339-1348
    • Kjems, L.L.1    Volund, A.2    Madsbad, S.3
  • 19
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man
    • DOI 10.1007/BF00280883
    • Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC 1985 Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28:412-419 (Pubitemid 15018832)
    • (1985) Diabetologia , vol.28 , Issue.7 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3
  • 22
    • 33744889983 scopus 로고
    • Inhibition of gastric emptying by glucagon-like peptide (7-36) amide in patients with type-2 diabetes mellitus
    • Abstract
    • Willms B, Werner J, Creutzfeldt W, Orskov C, Holst J, Nauck M 1994 Inhibition of gastric emptying by glucagon-like peptide (7-36) amide in patients with type-2 diabetes mellitus. Diabetologia 37:A118 (Abstract)
    • (1994) Diabetologia , vol.37
    • Willms, B.1    Werner, J.2    Creutzfeldt, W.3    Orskov, C.4    Holst, J.5    Nauck, M.6
  • 24
    • 0034798916 scopus 로고    scopus 로고
    • How useful is paracetamol absorption as a marker of gastric emptying? A systematic literature study
    • DOI 10.1023/A:1011935603893
    • Willems M, Quartero AO, Numans ME 2001 How useful is paracetamol absorption as a marker of gastric emptying? A systematic literature study. Dig Dis Sci 46:2256-2262 (Pubitemid 32955241)
    • (2001) Digestive Diseases and Sciences , vol.46 , Issue.10 , pp. 2256-2262
    • Willems, M.1    Otto, Q.A.2    Numans, M.E.3
  • 25
    • 63649127788 scopus 로고    scopus 로고
    • Paracetamol absorption test with Wagner-Nelson analysis for safe and accurate measurements of gastric emptying in women
    • Sanaka M, Nakada K 2008 Paracetamol absorption test with Wagner-Nelson analysis for safe and accurate measurements of gastric emptying in women. Methods Find Exp Clin Pharmacol 30:753-756
    • (2008) Methods Find Exp Clin Pharmacol , vol.30 , pp. 753-756
    • Sanaka, M.1    Nakada, K.2
  • 26
    • 77949813926 scopus 로고    scopus 로고
    • Glucagon responses to increasing oral loads of glucose and corresponding isoglycemic intravenous glucose infusions in patients with type 2 diabetes and healthy subjects
    • Abstract
    • Knop F, Bagger J, Lund A, Vestergaard H, Holst J, Vilsboll T 2009 Glucagon responses to increasing oral loads of glucose and corresponding isoglycemic intravenous glucose infusions in patients with type 2 diabetes and healthy subjects. Diabetes 58:A368 (Abstract)
    • (2009) Diabetes , vol.58
    • Knop, F.1    Bagger, J.2    Lund, A.3    Vestergaard, H.4    Holst, J.5    Vilsboll, T.6
  • 27
    • 77954944284 scopus 로고    scopus 로고
    • Reduced glucose tolerance and insulin resistance induced by steroid treatment, relative physical inactivity, and high-calorie diet impairs the incretin effect in healthy subjects
    • Hansen KB, Vilsbøll T, Bagger JI, Holst JJ, Knop FK 2010 Reduced glucose tolerance and insulin resistance induced by steroid treatment, relative physical inactivity, and high-calorie diet impairs the incretin effect in healthy subjects. J Clin Endocrinol Metab 95:3309-3317
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 3309-3317
    • Hansen, K.B.1    Vilsbøll, T.2    Bagger, J.I.3    Holst, J.J.4    Knop, F.K.5
  • 28
    • 0001095690 scopus 로고    scopus 로고
    • Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients
    • Vilsbøll T, Krarup T, Deacon CF, Madsbad S, Holst JJ 2001 Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients. Diabetes 50:609-613 (Pubitemid 32195226)
    • (2001) Diabetes , vol.50 , Issue.3 , pp. 609-613
    • Vilsboll, T.1    Krarup, T.2    Deacon, C.F.3    Madsbad, S.4    Holst, J.J.5
  • 29
    • 0037312821 scopus 로고    scopus 로고
    • The influence of GLP-1 on glucose-stimulated insulin secretion: Effects on β-cell sensitivity in type 2 and nondiabetic subjects
    • DOI 10.2337/diabetes.52.2.380
    • Kjems LL, Holst JJ, Vølund A, Madsbad S 2003 The influence of GLP-1 on glucose-stimulated insulin secretion: effects on β-cell sensitivity in type 2 and nondiabetic subjects. Diabetes 52:380-386 (Pubitemid 36173193)
    • (2003) Diabetes , vol.52 , Issue.2 , pp. 380-386
    • Kjems, L.L.1    Holst, J.J.2    Volund, A.3    Madsbad, S.4
  • 30
    • 0036373430 scopus 로고    scopus 로고
    • Defective amplification of the late phase insulin response to glucose by gip in obese type ii diabetic patients
    • DOI 10.1007/s00125-002-0878-6
    • Vilsbøll T, Krarup T, Madsbad S, Holst JJ 2002 Defective amplification of the late phase insulin response to glucose by GIP in obese Type II diabetic patients. Diabetologia 45:1111-1119 (Pubitemid 34985287)
    • (2002) Diabetologia , vol.45 , Issue.8 , pp. 1111-1119
    • Vilsboll, T.1    Krarup, T.2    Madsbad, S.3    Holst, J.4
  • 31
    • 57749122065 scopus 로고    scopus 로고
    • Redcuced incretin effect in obese subjects with normal glucose tolerance as compared to lean control subjects
    • Abstract
    • Knop F, Aaboe K, Vilsboll T, Madsbad S, Holst J, Krarup T 2008 Redcuced incretin effect in obese subjects with normal glucose tolerance as compared to lean control subjects. Diabetes 57:A410 (Abstract)
    • (2008) Diabetes , vol.57
    • Knop, F.1    Aaboe, K.2    Vilsboll, T.3    Madsbad, S.4    Holst, J.5    Krarup, T.6
  • 32
    • 33847682160 scopus 로고    scopus 로고
    • Inappropriate suppression of glucagon during OGTT but not during isoglycaemic i.v. glucose infusion contributes to the reduced incretin effect in type 2 diabetes mellitus
    • DOI 10.1007/s00125-006-0566-z
    • Knop FK, Vilsbøll T, Madsbad S, Holst JJ, Krarup T 2007 Inappropriate suppression of glucagon during OGTT but not during isoglycaemic i.v. glucose infusion contributes to the reduced incretin effect in type 2 diabetes mellitus. Diabetologia 50:797-805 (Pubitemid 46355821)
    • (2007) Diabetologia , vol.50 , Issue.4 , pp. 797-805
    • Knop, F.K.1    Vilsboll, T.2    Madsbad, S.3    Holst, J.J.4    Krarup, T.5
  • 33
    • 58149467276 scopus 로고    scopus 로고
    • Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes
    • Højberg PV, Vilsbøll T, Rabøl R, Knop FK, Bache M, Krarup T, Holst JJ, Madsbad S 2009 Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes. Diabetologia 52:199-207
    • (2009) Diabetologia , vol.52 , pp. 199-207
    • Højberg, P.V.1    Vilsbøll, T.2    Rabøl, R.3    Knop, F.K.4    Bache, M.5    Krarup, T.6    Holst, J.J.7    Madsbad, S.8
  • 35
    • 0015122757 scopus 로고
    • Maximum tubular reabsorption capacity for glucose and renal hemodynamcis during rapid hypertonic glucose infusion in normal and diabetic subjects
    • Mogensen CE 1971 Maximum tubular reabsorption capacity for glucose and renal hemodynamcis during rapid hypertonic glucose infusion in normal and diabetic subjects. Scand J Clin Lab Invest 28:101-109
    • (1971) Scand J Clin Lab Invest , vol.28 , pp. 101-109
    • Mogensen, C.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.