ANG II type i receptor antagonism improved nitric oxide production and enhanced eNOS and PKB/Akt expression in hearts from a rat model of insulin resistance

Molecular and Cellular Biochemistry

Volumn 349, Issue 1-2, 2011, Pages 21-31

  Huisamen, B ^a,b   Perel S J C ^b   Friedrich, S O ^b   Salie, R ^b   Strijdom, H ^b   Lochner, A ^a,b  

^a STELLENBOSCH UNIVERSITY   (South Africa)

^b UNIVERSITY OF STELLENBOSCH   (South Africa)

Author keywords

Angiotensin II; eNOS; Insulin resistance; Losartan; Nitric oxide; PKB Akt

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; ENDOTHELIAL NITRIC OXIDE SYNTHASE; LOSARTAN; NITRIC OXIDE; PROTEIN KINASE B;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FLOW CYTOMETRY; HEART; HEART FUNCTION; INSULIN RESISTANCE; NONHUMAN; OBESITY; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; WESTERN BLOTTING;

ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; CARDIAC OUTPUT; DIET; INSULIN RESISTANCE; LOSARTAN; MALE; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; OBESITY; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

ANIMALIA; RATTUS;

EID: 79952283015     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-010-0656-6     Document Type: Article

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