The development of activating and inhibiting camelid VHH domains against human protein kinase C epsilon

European Journal of Pharmaceutical Sciences

Volumn 42, Issue 4, 2011, Pages 332-339

  Paalanen, Milla M I ^a,b   Ekokoski, Elina ^b   El Khattabi, Mohamed ^a   Tuominen, Raimo K ^b   Verrips, C Theo ^a   Boonstra, Johannes ^a   Blanchetot, Christophe ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Kinase activity; Phage display; Protein kinase C; VHH antibody

Indexed keywords

ANTIGEN BINDING REGION OF CAMELID SINGLE CHAIN ANTIBODY; COMPLEMENTARY DNA; ISOENZYME; MONOCLONAL ANTIBODY; PROTEIN KINASE C; PROTEIN KINASE C DELTA; PROTEIN KINASE C EPSILON; PROTEIN KINASE C GAMMA; PROTEIN KINASE C THETA; RECOMBINANT ENZYME; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; UNCLASSIFIED DRUG;

ANTIGEN BINDING; ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; IMMUNOPRECIPITATION; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; CAMELIDS, NEW WORLD; COMPLEMENTARITY DETERMINING REGIONS; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; INHIBITORY CONCENTRATION 50; ISOENZYMES; PEPTIDE LIBRARY; PROTEIN BINDING; PROTEIN KINASE C-EPSILON; SINGLE-CHAIN ANTIBODIES;

EID: 79952281440     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2010.12.012     Document Type: Article

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