Drug delivery applications of non-lamellar liquid crystalline phases and nanoparticles

Journal of Drug Delivery Science and Technology

Volumn 21, Issue 1, 2011, Pages 101-109

  Tiberg, F ^a   Johnsson, M ^a  

^a Ideon Science Park   (Sweden)

Author keywords

Controlled release; Diglyceride; Drug delivery; Lipid; Liquid crystalline; Monoglyceride; Nanoparticles; Phosphatidyl choline; Self assembly

Indexed keywords

AMPHOPHILE; BUPRENORPHINE; CINNARIZINE; COPOLYMER; DIPHTHERIA VACCINE; DOCETAXEL; DOXORUBICIN; DRUG CARRIER; GLYCEROL OLEATE; LIPID; NANOPARTICLE; POLOXAMER; POLYSORBATE 80; SMALL INTERFERING RNA; SOMATOSTATIN 14; SURFACTANT;

CHEMICAL STRUCTURE; DIFFUSION; DRUG DELIVERY SYSTEM; DRUG RELEASE; ENCAPSULATION; GEOMETRY; HUMAN; LIQUID CRYSTAL; NONHUMAN; PHYSICAL CHEMISTRY; REVIEW; SINGLE DRUG DOSE; SOLUBILIZATION; TUMOR;

EID: 79952241018     PISSN: 17732247     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1773-2247(11)50009-7     Document Type: Review

References (67)

1. Larsson K. - Cubic lipid-water phases - structures and biomembrane aspects. - J. Phys. Chem.,, 93, 7304-7314, 1989.
2. Lindblom G., Rilfors L. - Cubic phases and isotropic structures formed by membrane-lipis - possible biological relevance. - Biochim. Biophys. Acta, 988, 221-256, 1989.
3. Seddon J. M. - Structure of the inverted hexagonal (HII) phase and non-lamellar phase-transitions of lipids. - Biochim. Biophys. Acta, 1031, 1-69, 1990.
4. Luzzati V., Vargas R., Mariani P., Gulik A., Delacroix H. - Cubic phases of lipid-containing systems - elements of a theory and biological connotations. - J. Mol. Biol., 229, 540-551, 1993.
5. Luzzati V., Husson F. - Structure of liquid-crystalline phases of lipid-water systems. - J. Cell Biol., 12, 207, 1962.
6. Engstrom S., Lindman B., Larsson K. - Method of preparing controlled-release preparations for biologically active materials and resulting compositions. - Int. Patent AppWO8402076, 1983.
7. Norling T., Lading P., Engström S., Larsson K., Krog N., Nissen S.S. - Formulation of a drug delivery system based on a mixture of monoglycerides and triglycerides for use in treatment of periodontal disease. - J. Clin. Periodont., 19, 687-692, 1992.
8. Shah J., Sadhale Y., Chilurkuri D. - Cubic phase gels as drug delivery systems. - Adv. Drug Del. Rev., 47, 229-250, 2001.
9. Drummond C.J., Fong C. - Surfactant self-assembly objects as novel drug delivery vehicles. - Current Opinion in Colloid & Interface Science, 4, 449-456, 1999. (Pubitemid 30449773)
10. Israelachvili J. N., Mitchell D. J., Ninham B. W. - Theory of self-assembly of lipid bilayers and vesicles. - Biochim. Biophys. Acta, 470, 185-201, 1977.
11. Larsson K., Fontell K., Krog N.- Structural relationships between lamellar cubic and hexagonal phases in monoglyceride-water systems - possibility of cubic structures in biological-systems. - Chemistry and Physics of Lipids, 27, 321-328, 1980.
12. Hyde S. T., Andersson S., Ericsson B., Larsson K. - A cubic structure consisting of a lipid bilayer forming aninfinite periodic minimum surface of the gyroid type in the glycerolmonooleate-water system. - Zeitschrift für Kristallographie, 168, 213-219, 1984.
13. Barauskas J., Cervin C., Jankunec M., Spandyreva M., Ribokaite K., Tiberg F., Johnsson M. - Interactions of lipid-based liquid crystalline nanoparticles with model and cell membranes. - Int. J. Pharm., in press, 2010.
14. Oradd G., Lindblom G., Fontell K., Ljusberg-Wahren H.- Phase-diagram of soybean phosphatidylcholine-diacylglycerol-water studied by X-ray-diffraction and P-31-NMR and pulsed-field gradient H-1 -NMR - evidence for reversed micelles in the cubic phase.- Biophys. J., 68, 1856-1863, 1995.
15. Thuresson K., Tiberg F., Johansson M., Harwigsson I., Johnsson M., Joabsson F. - EP1768650: Liquid Depot Formulations. - 2005.
16. Wyatt D., Dorschel D. - A cubic-phase delivery system composed of flycerol monooleate and water for sustained release of water soluble drugs. - Pharm. Technol., 16, 116-130, 1992.
17. Geraghty P. B., Attwood D., Collett J. H., Dandiker Y. - The in vitro release of some antimuscarinic drugs from monoolein/water lyotropic liquid crystalline gels. - Pharm. Res., 13, 1265-1271, 1996.
18. Lindell K., Engblom J., Jonstromer M., Carlsson A., Engstrom S. - Influence of a charged phospholipid on the release pattern of timolol maleate from cubic liquid crystalline phases. - In: Colloid Science of Lipids, New Paradigms for Self-Assembly in Science and Technology, Lindman B., Ninham B.W. Eds., 1998, pp. 111-118.
19. Chang C. M., Bodmeier R. - Swelling of and drug release from monoglyceride-based drug delivery systems. - J. Pharm. Sci., 86, 747-752, 1997.
20. Burrows R., Collett J. H., Attwood D. -The release of drugs from monoglyceride-water liquid-crystalline phases. - Int. J. Pharm., 111, 283-293, 1994.
21. Leslies. B., Puvvada S., Ratna B. R., Rudolph A. S.- Encapsulation of hemoglobin in a bicontinuous cubic phase lipid. - Biochim. Biophys. Acta, Biomembranes, 1285, 246-254, 1996. (Pubitemid 26403083)
22. Sadhale Y Shah J.C. - Glyceryl monooleate cubic phase gel as chemical stability enhancer of cefazolin and cefuroxime.- Pharm. Dev. Tech., 3 (4), 549-556, 1998.
23. Sadhale Y., Shah J. C. - Stabilization of insulin against agitation-induced aggregation by the GMO cubic phase gel. - Int. J. Pharm., 191, 51-64, 1999.
24. Sadhale Y., Shah J. C. - Biological activity of insulin in GMO gels and the effect of agitation. - Int. J. Pharm., 191, 65-74, 1999.
25. Clogston J., Caffrey M. - Controlling release from the lipidic cubic phase. Amino acids peptides proteins and nucleic acids. - J. Control. Release, 107, 97-111, 2005.
26. Engstrom S., Engstrom L. - Phase-behavior of the lidocaine-monoolein- water system. - Int. J. Pharm., 79, 113-122, 1992.
27. Registered trademark of Camurus AB, Lund, Sweden (www.camurus.com).
28. Ericsson B., Eriksson P.O., Löfroth J. E., Engström S. - Cubic phases as delivery systems for peptide drugs. - ACS Symposium Series 469, 251-265, 1991.
29. Johnsson M., Nistor C., Tiberg F. - Long-acting release of short-acting peptides; case study with somatostatin(1-14). - CRS Meeting abstract, 2009.
30. Cervin C., Vandoolaeghe P., Nistor C., Tiberg F., Johnsson M. - A combined in vitro and in vivo study on the interactions between somatostatin and lipid-based liquid crystalline drug carriers and bilayers. - Eur. J. Pharm. Sci., 36, 377-385, 2009.
31. Thuresson K., Tiberg F., Johansson M., Harwigsson I., Joabsson F., Johnsson M. - US20070265190A1: Opioid depot formulations - US2007000798495, 2007.
32. Nielsen L. S., Schubert L., Hansen J. - Bioadhesive drug delivery systems - I. Characterisation of mucoadhesive properties of systems based on glyceryl mono-oleate and glyceryl monolinoleate. - Eur. J. Pharm. Sci., 6, 231-239, 1998.
33. Tiberg F., Cavallin-Ståhl E., Linden M., Thuresson K., Hadjieva T. - Treatment of oral mucositis pain by a bioadhesive barrier forming lipid solution. - Support Care in Cancer, 17, 918, 2009.
34. Boyd B.J., Khoo S.M., Whittaker D.V., Davey G., Porter C.J.H. - A lipid-based liquid crystalline matrix that provides sustained release and enhanced oral bioavailability for a model poorly water soluble drug in rats. - Int. J. Pharm., 340, 52-60, 2007.
35. Strickley R.G. - Solubilizing excipients in oral and injectable formulations. - Pharm. Res., 21, 201-230, 2004.
36. Lasic D. D. - Liposomes: From Physics to Applications. - Elsevier Science Publishers, Amsterdam, 1993.
37. Bangham A.D., Standish M.M., Watkins J.C. - Diffusion of univalent ions across lamellae of swollen phospholipids. - J. Mol. Biol., 13, 238, 1965.
38. Winterhalter M., Frederik P.M., Vallner J.J., Lasic D.D.-Stealth(R) liposomes: from theory to product. - Adv. Drug Del. Rev., 24, 165-177, 1997.
39. Adler-Moore J.P., Proffitt R.T. - Development characterization efficacy and mode of action of Ambisome a unilamellar liposomal formulation of amphotericin. - B. J. Liposome Res., 3, 429-450, 1993.
40. Barauskas J., Johnsson M., Joabsson F., Tiberg F. - Cubic phase nanoparticles (cubosome): principles for controlling size structure and stability. - Langmuir, 21, 2569-2577, 2005. (Pubitemid 40421910)
41. Barauskas J., Johnsson M., Tiberg F. - Self-assembled lipid superstructures: beyond vesicles and liposomes. - Nano Letters, 5, 1615-1619, 2005. (Pubitemid 41251697)
42. Johnsson M., Barauskas J., Tiberg F. - Cubic phases and cubic phase dispersions in a phospholipid-based system. - J. Am. Chem. Soc., 127, 1076-1077, 2005.
43. Gustafsson J., Ljusberg-Wahren H., Almgren M., Larsson K. - Submicron particles of reversed lipid phases in water stabilized by a nonionic amphiphilic polymer. - Langmuir, 13, 6964-6971, 1997. (Pubitemid 127601886)
44. Boyd B. J., Dong Y. D., Rades T. - Non-lamellar liquid crystalline nanostructured particles: advances in materials and structure determination. - J. Liposome Research, 19, 12-28, 2009.
45. Yagmur A., Glatter O. - Characterization and potential application of nanostructured aqueous dispersions. - Adv. Colloid Interface Sci., 147-148, 333-342, 2009.
46. Johnsson M., Barauskas J., Norlin A., Tiberg F. - Physicochemical and drug delivery aspects of lipid-based liquid crystalline nanoparticles: a case study of intravenously administered propofol. - J. Nanosci. Nanotechnol., 6, 3017-3024, 2006.
47. Johnsson M., Lam Y., Barauskas J., Tiberg F. - Aqueous phase behavior and dispersed nanoparticles of diglycerol monooleate/glycerol dioleate mixtures. - Langmuir, 21, 5159-5165, 2005. (Pubitemid 40795341)
48. Barauskas J., Audrius M., Gunnarsson T., Tiberg F., Johnsson M. - "Sponge" nanoparticle dispersions in aqueous mixtures of diglycerol monooleate glycerol dioleate and polysorbate 80. - Langmuir, 22, 6328-6334, 2006.
49. Johnsson M., Edwards K. - Phase behavior and aggregate structure in mixtures of dioleoylphosphatidylethanolamine and poly(ethylene glycol)-lipids. - Biophys. J., 80, 313-323, 2001.
50. Johnsson M., Bergstrand N. - Phase behavior of DOPE/TritonX100 (reduced) in dilute aqueous solution: aggregate structure and pH-dependence. - Colloids and Surfaces B-Biointerfaces, 34, 69-76, 2004. (Pubitemid 38292201)
51. Barauskas J., Cervin C., Tiberg F., Johnsson M. - Structure of lyotropic self-assembled lipid nonlamellar liquid crystals and their nanoparticles in mixtures of phosphatidyl choline and alpha-tocopherol (vitamin E). - Physical Chemistry Chemical Physics, 10, 6483-6485, 2008.
52. Rangelov S., Almgren M. - Particulate and bulk bicontinuous cubic phases obtained from mixtures of glyceryl monooleate and copolymers bearing blocks of lipid-mimetic anchors in water. - J. Phys. Chem., B, 109, 3921-3929, 2005. (Pubitemid 40402270)
53. Spicer P.T., Hayden K.L., Lynch M.L., Ofori-Boateng A., Burns J.L. - Novel process for producing cubic liquid crystalline nanoparticles (cubosomes). - Langmuir, 17, 5748-5756, 2001.
54. Allen T.M. - Long-circulating (sterically stabilized) liposomes for targeted drug delivery. - Trends Pharmacol. Sci., 15, 215-220, 1995.
55. Chen M.L. - Lipid excipients and delivery systems for pharmaceutical development: a regulatory perspective. - Adv. Drug Del. Rev., 60, 768-777, 2008.
56. rd Int. Symp. Control. Rel. Bioact. Mater., 1996, pp. 89-90.
57. Cervin C., Tinzl M., Johnsson M., Abrahamsson P-A., Tiberg F., Dizeyi N. - Properties and effects of a novel liquid crystal nanoparticle formulation of docetaxel in a prostate cancer mouse model. - Eur. J. Pharm. Sci., 41, 369-375, 2010.
58. Boyd B. J., Whittaker D. V., Khoo S. M., Davey G. - Hexosomes formed from glycerate surfactants, Formulation as a colloidal carrier for irinotecan. - Int. J. Pharm., 318, 154-162, 2006.
59. Zuhorn I. S., Engberts J., Hoekstra D. - Gene delivery by cationic lipid vectors: overcoming cellular barriers. - European Biophysics Journal with Biophysics Letters, 36, 349-362, 2007.
60. Ewert K., Slack N.L., Ahmad A., Evans H.M., Lin A.J., Samuel C.E., Safinya C.R. - Cationic lipid-DNA complexes for gene therapy: Understanding the relationship between complex structure and gene delivery pathways at the molecular level. -Current Medicinal Chemistry, 11, 133-149, 2004.
61. Gustafsson J., Arvidson G., Karlsson G., Almgren M. - Complexes between cationic liposomes and DNA visualized by CRYO-TEM - Biochim. Biophys. Acta, Biomembranes, 1235, 305-312, 1995.
62. Almsherqi Z., Hyde S., Ramachandran M., Deng Y. - Cubic membranes: a structure-based design for DNA uptake. - J. Royal Society Interface, 5, 1023-1029, 2008.
63. Johnsson M., Joabsson F., Tiberg F. - Compositions forming non-lamellar dispersions. -Int. Patent App. WO2006/013369, 2006.
64. Haile M., Schroder U., Hamasur B., Pawlowski A., Jaxmar T., Kallenius G., Svenson S.B. - Immunization with heat-killed Mycobacterium bovis bacille Calmette-Guerin (BCG) in Eurocine (TM) L3 adjuvant protects against tuberculosis. - Vaccine, 22, 1498-1508, 2004.
65. Shah N., Carvajal M., Patel C., Infeld M., Malick A. - Self-emulsifying drug delivery systems (SEDDS) with polyglycolyzed glycerides for improving in vitro dissolution and oral absorption of lipophilic drugs. - Int. J. Pharm., 106, 15-23, 1994.
66. Kommuru T., Gurley B., Khan M., Reddy I. - Self-emulsifying drug delivery systems (SEDDS) of coenzyme Q10: formulation development and bioavailability assessment. - Int. J. Pharm., 212, 233-246, 2001.
67. O'Driscoll C. - Lipid-based formulations for intestinal lymphatic delivery. - Eur. J. Pharm. Sci., 15, 405-415, 2002.