Fructus ligustri lucidi extracts induce human glioma cell death through regulation of Akt/mTOR pathway in vitro and reduce glioma tumor growth in U87MG xenograft mouse mode

Phytotherapy Research

Volumn 25, Issue 3, 2011, Pages 429-434

  Jeong, Ji Cheon ^a   Kim, Jin Won ^a   Kwon, Chae Hwa ^b   Kim, Thae Hyun ^b   Kim, Yong Keun ^b  

^a Dongguk University   (South Korea)

^b Pusan National University School of Medicine   (South Korea)

Author keywords

Akt mTOR; Cell viability; Fructus ligustri lucidi; Human glioma cells; Surviving; Tumor growth

Indexed keywords

LIGUSTRUM LUCIDUM EXTRACT; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RAPAMYCIN; SURVIVIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; FLOW CYTOMETRY; FRUCTUS LIGUSTRI LUCIDI; GENE EXPRESSION; GENE OVEREXPRESSION; GLIOBLASTOMA; GLIOMA CELL; MALE; MEDICINAL PLANT; MOUSE; NONHUMAN; TUMOR GROWTH; TUMOR VOLUME; TUMOR XENOGRAFT; WESTERN BLOTTING;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; LIGUSTRUM; MICE; PHOSPHATIDYLINOSITOL 3-KINASES; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS C-AKT; TOR SERINE-THREONINE KINASES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MAMMALIA;

EID: 79952233382     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3265     Document Type: Article

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