Loss of histone acetyltransferase cofactor transformation/transcription domain-associated protein impairs liver regeneration after toxic injury

Hepatology

Volumn 53, Issue 3, 2011, Pages 954-963

  Shukla, Vivek ^a,b   Cuenin, Cyrille ^a   Dubey, Nileshkumar ^b   Herceg, Zdenko ^a  

^a INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON TETRACHLORIDE; HISTONE ACETYLTRANSFERASE; TRANSCRIPTION FACTOR; TRANSFORMATION/TRANSCRIPTION DOMAIN ASSOCIATED PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CYCLE; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CHROMATIN; CONTROLLED STUDY; HISTONE ACETYLATION; IN VIVO STUDY; KNOCKOUT MOUSE; LIVER CELL; LIVER INJURY; LIVER REGENERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN MODIFICATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CARBON TETRACHLORIDE POISONING; CELL CYCLE; CELL PROLIFERATION; CYCLINS; DRUG-INDUCED LIVER INJURY; HISTONE ACETYLTRANSFERASES; LIVER REGENERATION; MICE; MICE, KNOCKOUT; NUCLEAR PROTEINS;

EID: 79952233097     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.24120     Document Type: Article

References (29)

1. Michalopoulos GK, DeFrances MC. Liver regeneration. Science 1997; 276: 60-66.
2. Fausto N. Liver regeneration and repair: hepatocytes, progenitor cells, and stem cells. HEPATOLOGY 2004; 39: 1477-1487.
3. Taub R. Liver regeneration: from myth to mechanism. Nat Rev Mol Cell Biol 2004; 5: 836-847.
4. Yu C, Wang F, Jin C, Wu X, Chan WK, McKeehan WL. Increased carbon tetrachloride-induced liver injury and fibrosis in FGFR4-deficient mice. Am J Pathol 2002; 161: 2003-2010.
5. Reed CA, Mayhew CN, McClendon AK, Yang X, Witkiewicz A, Knudsen ES. RB has a critical role in mediating the in vivo checkpoint response, mitigating secondary DNA damage and suppressing liver tumorigenesis initiated by aflatoxin B1. Oncogene 2009; 28: 4434-4443.
6. Taniguchi M, Magata S, Suzuki T, Shimamura T, Jin MB, Iida J, et al. Dipyridamole protects the liver against warm ischemia and reperfusion injury. J Am Coll Surg 2004; 198: 758-769.
7. Shepard BD, Tuma PL. Alcohol-induced protein hyperacetylation: mechanisms and consequences. World J Gastroenterol 2009; 15: 1219-1230.
8. Agalioti T, Chen G, Thanos D. Deciphering the transcriptional histone acetylation code for a human gene. Cell 2002; 111: 381-392.
9. Murr R, Vaissiere T, Sawan C, Shukla V, Herceg Z. Orchestration of chromatin-based processes: mind the TRRAP. Oncogene 2007; 26: 5358-5372.
10. Herceg Z, Hulla W, Gell D, Cuenin C, Lleonart M, Jackson S, et al. Disruption of Trrap causes early embryonic lethality and defects in cell cycle progression. Nat Genet 2001; 29: 206-211.
11. Frank SR, Schroeder M, Fernandez P, Taubert S, Amati B. Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation. Genes Dev 2001; 15: 2069-2082.
12. Frank SR, Parisi T, Taubert S, Fernandez P, Fuchs M, Chan HM, et al. MYC recruits the TIP60 histone acetyltransferase complex to chromatin. EMBO Rep 2003; 4: 575-580.
13. Li H, Cuenin C, Murr R, Wang ZQ, Herceg Z. HAT cofactor Trrap regulates the mitotic checkpoint by modulation of Mad1 and Mad2 expression. EMBO J 2004; 23: 4824-4834.
14. Loizou JI, Oser G, Shukla V, Sawan C, Murr R, Wang ZQ, et al. Histone acetyltransferase cofactor Trrap is essential for maintaining the hematopoietic stem/progenitor cell pool. J Immunol 2009; 183: 6422-6431.
15. Taubert S, Gorrini C, Frank SR, Parisi T, Fuchs M, Chan HM, et al. E2F-dependent histone acetylation and recruitment of the Tip60 acetyltransferase complex to chromatin in late G1. Mol Cell Biol 2004; 24: 4546-4556.
16. Kuhn R, Schwenk F, Aguet M, Rajewsky K. Inducible gene targeting in mice. Science 1995; 269: 1427-1429.
17. Rudolph KL, Chang S, Millard M, Schreiber-Agus N, DePinho RA. Inhibition of experimental liver cirrhosis in mice by telomerase gene delivery. Science 2000; 287: 1253-1258.
18. Herceg Z, Li H, Cuenin C, Shukla V, Radolf M, Steinlein P, et al. Genome-wide analysis of gene expression regulated by the HAT cofactor Trrap in conditional knockout cells. Nucleic Acids Res 2003; 31: 7011-7023.
19. Meng Z, Wang Y, Wang L, Jin W, Liu N, Pan H, et al. FXR regulates liver repair after CCl4-induced toxic injury. Mol Endocrinol 2010; 24: 886-897.
20. Sylvester AM, Chen D, Krasinski K, Andres V. Role of c-fos and E2F in the induction of cyclin A transcription and vascular smooth muscle cell proliferation. J Clin Invest 1998; 101: 940-948.
21. Adachi S, Obaya AJ, Han Z, Ramos-Desimone N, Wyche JH, Sedivy JM. c-Myc is necessary for DNA damage-induced apoptosis in the G(2) phase of the cell cycle. Mol Cell Biol 2001; 21: 4929-4937.
22. Zheng ZY, Weng SY, Yu Y. Signal molecule-mediated hepatic cell communication during liver regeneration. World J Gastroenterol 2009; 15: 5776-5783.
23. Morgan DO. SnapShot: cell-cycle regulators II. Cell 2008; 135: 974-974 e971.
24. Morgan DO. SnapShot: cell-cycle regulators I. Cell 2008; 135: 764-764 e761.
25. Berasain C, Garcia-Trevijano ER, Castillo J, Erroba E, Lee DC, Prieto J, et al. Amphiregulin: an early trigger of liver regeneration in mice. Gastroenterology 2005; 128: 424-432.
26. Desbois-Mouthon C, Wendum D, Cadoret A, Rey C, Leneuve P, Blaise A, et al. Hepatocyte proliferation during liver regeneration is impaired in mice with liver-specific IGF-1R knockout. FASEB J 2006; 20: 773-775.
27. Natarajan A, Wagner B, Sibilia M. The EGF receptor is required for efficient liver regeneration. Proc Natl Acad Sci U S A 2007; 104: 17081-17086.
28. Bouchard C, Dittrich O, Kiermaier A, Dohmann K, Menkel A, Eilers M, et al. Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter. Genes Dev 2001; 15: 2042-2047.
29. Fernandez PC, Frank SR, Wang L, Schroeder M, Liu S, Greene J, et al. Genomic targets of the human c-Myc protein. Genes Dev 2003; 17: 1115-1129.