Advancing in-vitro drug precipitation testing: New process monitoring tools and a kinetic nucleation and growth model

Journal of Pharmacy and Pharmacology

Volumn 63, Issue 3, 2011, Pages 333-341

  Arnold, Yvonne E ^a,b   Imanidis, Georgios ^a,b   Kuentz, Martin T ^a  

^a UNIVERSITY OF APPLIED SCIENCES AND ARTS NORTHWESTERN SWITZERLAND   (Switzerland)

^b UNIVERSITY OF BASEL   (Switzerland)

Author keywords

Drug precipitation; Dynamic image analysis; Kinetic nucleation and growth model; Raman spectroscopy

Indexed keywords

AMMONIUM ACETATE; DIETHYLAMINE; DIPYRIDAMOLE; MALEIC ACID; OLEATE SODIUM; SODIUM CHLORIDE; SODIUM HYDROXIDE;

ARTICLE; DRUG SOLUBILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMAGE ANALYSIS; IN VITRO STUDY; INTESTINE; MATHEMATICAL MODEL; PARTICLE SIZE; PRECIPITATION; RAMAN SPECTROMETRY; STOMACH; STOMACH JUICE;

CHEMICAL PRECIPITATION; DIPYRIDAMOLE; HUMANS; HYDROGEN-ION CONCENTRATION; INTESTINE, SMALL; MODELS, BIOLOGICAL; MODELS, STATISTICAL; PHARMACEUTICAL PREPARATIONS; PLATELET AGGREGATION INHIBITORS; SOLUBILITY; SPECTRUM ANALYSIS, RAMAN; STOMACH;

EID: 79952224616     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.2042-7158.2010.01228.x     Document Type: Article

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