Effect of combination therapy with sodium ozagrel and panax ginseng on transient cerebral ischemia model in rats

Journal of Biomedicine and Biotechnology

Volumn 2010, Issue , 2010, Pages

  Jang, Kyung Sool ^a   Park, Sang In ^a   Jang, Dong Kyu ^a   Han, Young Min ^a   Sunwoo, Yun Young ^a   Park, Moon Seo ^a   Chung, Yong An ^a   Maeng, Lee So ^a   Im, Ruth ^a   Kim, Min Wook ^a   Jeun, Sin Soo ^b  

^a Bupyeong gu   (South Korea)

^b The Catholic University of Korea   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

GINSENG EXTRACT; OZAGREL; TRIPHENYLTETRAZOLIUM; CELL NUCLEUS ANTIGEN; FIBRINOLYTIC AGENT; HERBACEOUS AGENT; METHACRYLIC ACID DERIVATIVE; NERVE PROTEIN; NEUN PROTEIN, RAT; NEUROPROTECTIVE AGENT;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTE; BRAIN BLOOD FLOW; BRAIN INFARCTION SIZE; CELL ACTIVATION; CELL EXPANSION; CELL SURVIVAL; CONTROLLED STUDY; DRUG EFFECT; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MONOTHERAPY; NERVE CELL INHIBITION; NEUROPROTECTION; NONHUMAN; RAT; ROTAROD TEST; TRANSIENT ISCHEMIC ATTACK; ANIMAL; CEREBRAL ARTERY DISEASE; DISEASE MODEL; DRUG COMBINATION; DRUG POTENTIATION; GINSENG; METABOLISM; NERVE CELL; PATHOLOGY;

ANIMALIA; METAMORPHA; PANAX GINSENG; RATTUS;

ANIMALS; ANTIGENS, NUCLEAR; APOPTOSIS; ASTROCYTES; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; DRUGS, CHINESE HERBAL; FIBRINOLYTIC AGENTS; INFARCTION, MIDDLE CEREBRAL ARTERY; ISCHEMIC ATTACK, TRANSIENT; METHACRYLATES; NERVE TISSUE PROTEINS; NEURONS; NEUROPROTECTIVE AGENTS; PANAX; RATS;

EID: 79952219914     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/2010/893401     Document Type: Article

References (24)

1. Klijn C. J. M., Hankey G. J., Management of acute ischaemic stroke: new guidelines from the American Stroke Association and European (Pubitemid 37311323)
2. Fawcett J. W., Asher R. A., The glial scar and central nervous system repair Brain Research Bulletin 1999 49 6 377 391 (Pubitemid 29385505)
3. Silver J., Miller J. H., Regeneration beyond the glial scar Nature Reviews Neuroscience 2004 5 2 146 156 (Pubitemid 38160289)
4. Wang Q., Sun A. Y., Simonyi A., Kalogeris T. J., Miller D. K., Sun G. Y., Korthuis R. J., Ethanol preconditioning protects against ischemia/reperfusion- induced brain damage: role of NADPH oxidase-derived ROS Free Radical Biology and Medicine 2007 43 7 1048 1060 (Pubitemid 47302653)
5. Mulvey J. M., Dorsch N. W. C., Mudaliar Y., Lang E. W., Multimodality monitoring in severe traumatic brain injury: the role of brain tissue oxygenation monitoring Neurocritical Care 2004 1 3 391 402 (Pubitemid 41278358)
6. Arii K., Igarashi H., Arii T., Katayama Y., The effect of ozagrel sodium on photochemical thrombosis in rat: therapeutic window and combined therapy with heparin sodium Life Sciences 2002 71 25 2983 2994 (Pubitemid 35221404)
7. Imamura T., Kiguchi S., Kobayashi K., Ichikawa K., Yamazaki Y., Kojima M., Effect of ozagrel, a selective thromboxane A2-synthetase inhibitor, on cerebral infarction in rats. Comparative study with norphenazone, a free-radical scavenger Arzneimittel-Forschung 2003 53 10 688 694 (Pubitemid 37357354)
8. Komatsu H., Takehana Y., Hamano S., Beneficial effect of OKY-046, a selective thromboxane A synthetase inhibitor, on experimental cerebral vasospasm Japanese Journal of Pharmacology 1986 41 3 381 391 (Pubitemid 16065347)
9. Suzuki S., Sano K., Handa H., Asano T., Tamura A., Yonekawa Y., Ono H., Tachibana N., Hanaoka K., Clinical study of OKY-046, a thromboxane synthetase inhibitor, in prevention of cerebral vasospasms and delayed cerebral ischaemic symptoms after subarachnoid haemorrhage due to aneurysmal rupture: a randomized double-blind study Neurological Research 1989 11 2 79 88 (Pubitemid 19179131)
10. Yoshikawa T., Akiyoshi Y., Susumu T., Tokado H., Fukuzaki K., Nagata R., Samukawa K., Iwao H., Kito GO., Ginsenoside Rb reduces neurodegeneration in the peri-infarct area of a thromboembolic stroke model in non-human primates Journal of Pharmacological Sciences 2008 107 1 32 40 (Pubitemid 351744082)
11. Bu Y., Jin Z. H., Park S. Y., Baek S., Rho S., Ha N., Park S. K., Kim S. Y., Kim H., Siberian ginseng reduces infarct volume in transient focal cerebral ischaemia in Sprague-Dawley rats Phytotherapy Research 2005 19 2 167 169 (Pubitemid 40646424)
12. Son H. Y., Han H. S., Jung H. W., Park Y. K., Panax notoginseng attenuates the infarct volume in rat ischemic brain and the inflammatory response of microglia Journal of Pharmacological Sciences 2009 109 3 368 379
13. Kaufman D. W., Kelly J. P., Rosenberg L., Anderson T. E., Mitchell A. A., Recent patterns of medication use in the ambulatory adult population of the United States: the Slone survey Journal of the American Medical Association 2002 287 3 337 344 (Pubitemid 34251967)
14. Kim Y. O., Kim H. J., Kim G. S., Park HO. G., Lim S. J., Seong N. S., Ham Y. W., Lee S. D., Jang KI. H., Jung K. H., Chung J. H., Kang S. A., Panax ginseng protects against global ischemia injury in rat hippocampus Journal of Medicinal Food 2009 12 1 71 76
15. Longa E. Z., Weinstein P. R., Carlson S., Cummins R., Reversible middle cerebral artery occlusion without craniectomy in rats Stroke 1989 20 1 84 91 (Pubitemid 19040218)
16. Radad K., Gille G., Liu L., Rausch W. D., Use of ginseng in medicine with emphasis on neurodegenerative disorders Journal of Pharmacological Sciences 2006 100 3 175 186
17. Han S. Y., Li H. X., Bai C. C., Wang L., Tu P. F., Component analysis and free radical-scavenging potential of Panax notoginseng and Carthamus tinctorius extracts Chemistry and Biodiversity 2010 7 2 383 391
18. Tian J., Fu F., Geng M., Jiang Y., Yang J., Jiang W., Wang C., Liu KE., Neuroprotective effect of 20(S)-ginsenoside Rg on cerebral ischemia in rats Neuroscience Letters 2005 374 2 92 97 (Pubitemid 40092203)
19. Ye R., Li N., Han J., Kong X., Cao R., Rao Z., Zhao G., Neuroprotective effects of ginsenoside Rd against oxygen-glucose deprivation in cultured hippocampal neurons Neuroscience Research 2009 64 3 306 310
20. Collombet J. M., Masqueliez C., Four E., Burckhart M. F., Bernab D., Baubichon D., Lallement G., Early reduction of NeuN antigenicity induced by soman poisoning in mice can be used to predict delayed neuronal degeneration in the hippocampus Neuroscience Letters 2006 398 3 337 342 (Pubitemid 43673712)
21. Cole D. J., Patel P. M., Schell R. M., Drummond J. C., Osborne T. N., Brain eicosanoid levels during temporary focal cerebral ischemia in rats: a microdialysis study Journal of Neurosurgical Anesthesiology 1993 5 1 41 47 (Pubitemid 23047283)
22. Grau A. J., Ruf A., Vogt A., Lichy C., Buggle F., Patscheke H., Hacke W., Increased fraction of circulating activated platelets in acute and previous cerebrovascular ischemia Thrombosis and Haemostasis 1998 80 2 298 301 (Pubitemid 28393627)
23. Van Kooten F., Ciabattoni G., Patrono C., Schmitz P. I. M., Van Gijn J., Koudstaal P. J., Evidence for episodic platelet activation in acute ischemic stroke Stroke 1994 25 2 278 281 (Pubitemid 24047245)
24. Heye N., Cervs-Navarro J., Microthromboemboli in acute infarcts: analysis of 40 autopsy cases Stroke 1996 27 3 431 434 (Pubitemid 26081437