Siberian ginseng reduces infarct volume in transient focal cerebral ischaemia in Sprague-Dawley rats

Phytotherapy Research

Volumn 19, Issue 2, 2005, Pages 167-169

  Bu, Yungmin ^a   Jin, Zhen Hua ^a   Park, Sun Young ^a   Baek, Sunkyung ^a   Rho, Sungju ^a   Ha, Nina ^a   Park, Seong Kyu ^a   Kim, Sun Yeo ^a   Kim, Hocheol ^a  

^a Kyung Hee University   (South Korea)

Author keywords

Acanthopanax senticosus; Focal ischaemia; Neuroprotection; Siberian ginseng; Traditional Korean medicine

Indexed keywords

CD11B ANTIGEN; CYCLOOXYGENASE 2; ELEUTHEROCOCCUS SENTICOSUS EXTRACT; ELEUTHEROSIDE B; ELEUTHEROSIDE E; GLYCOSIDE; PROTEIN OX 42; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BARK; BRAIN INFARCTION; BRAIN ISCHEMIA; CELL ACTIVATION; CONTROLLED STUDY; DRUG ISOLATION; ELEUTHEROCOCCUS SENTICOSUS; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; INFLAMMATION; KOREA; MALE; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; PLANT ROOT; RAT; RAT STRAIN; TRADITIONAL MEDICINE;

ANIMALS; BRAIN ISCHEMIA; CEREBRAL CORTEX; CEREBRAL INFARCTION; ELEUTHEROCOCCUS; HUMANS; INJECTIONS, INTRAPERITONEAL; MIDDLE CEREBRAL ARTERY; NEUROPROTECTIVE AGENTS; PHYTOTHERAPY; PLANT EXTRACTS; PLANT ROOTS; PLANT STEMS; RATS; RATS, SPRAGUE-DAWLEY;

ACANTHOPANAX; ELEUTHEROCOCCUS SENTICOSUS; PANAX GINSENG;

EID: 18444371088     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ptr.1649     Document Type: Article

References (10)

1. Bhat RV, DiRocco R, Marcy VR, et al. 1996. Increased expression of IL-1beta converting enzyme in hippocampus after ischemia: selective localization in microglia. J Neurosci 16: 4146-4154.
2. Deyama T, Nishibe S, Nakazawa Y. 2001. Constituents and pharmacological effects of Eucommia and Siberian Ginseng. Acta Pharmacol Sin 22: 1057-1070.
3. Feuerstein GZ, Wang X, Barone FC. 1997. Inflammatory gene expression in cerebral ischemia and trauma. Potential new therapeutic targets. Ann N Y Acad Sci 825: 179-193.
4. Man L, Cai D. 1998. Clinical and experimental study on treatment of acute cerebral infarction with Acanthopanax injection. Zhongguo Zhong Xi Yi Jie He Za Zhi 18: 472-474.
5. Kreutzberg GW. 1996. Microglia: a sensor for pathological events in the CNS. Trends Neurosci 19: 312-318.
6. Longa EZ, Weinstein PR, Carlson S, Cummins R. 1989. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 20: 84-91.
7. Nogawa S, Zhang F, Ross ME, Iadecola C. 1997. Cyclooxygenase-2 gene expression in neurons contributes to ischemic brain damage. J Neurosci 17: 2746-2755.
8. Shen ML, Zhai SK, Chen HL, Luo YD, Tu GR, Ou DW. 1991. Immunopharmacological effects of polysaccharides from Acanthopanax senticosus on experimental animals. Int J Immunopharmacol 13: 549-554.
9. Shi Z, Liu C, Li R. 1990. Effect of a mixture of Acanthopanax senticosus and Elsholtzia splendens on serum-lipids in patients with hyperlipemia. Zhong Xi Yi Jie He Za Zhi 10: 155-156.
10. Sui DY, Lu ZZ, Ma LN, Fan ZG. 1994. Effects of the leaves of Acanthopanax senticosus (Rupr. et Maxim.) Harms, on myocardial infarct size in acute ischemic dogs. Zhongguo Zhong Yao Za Zhi 19: 746-747.