Thrombopoietin receptor levels in tumor cell lines and primary tumors

Journal of Oncology

Volumn , Issue , 2010, Pages

  Erickson Miller, Connie L ^a   Chadderton, Antony ^a   Gibbard, Anna ^a   Kirchner, Jennifer ^a   Pillarisetti, Kodandaram ^a   Baker, Katherine ^a   Pandite, Lini ^a   El Hariry, Iman ^a   Mostafa Kamel, Yasser ^b   Liu, Yuan ^a   Martin, Anne Marie ^a   Messam, Conrad ^a  

^a GLAXOSMITHKLINE   (United States)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ELTROMBOPAG; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ERYTHROPOIETIN RECEPTOR; MESSENGER RNA; SOMATOMEDIN C; THROMBOPOIETIN RECEPTOR;

ARTICLE; COLON CANCER; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; KIDNEY CARCINOMA; LYMPHOMA; MICROARRAY ANALYSIS; OSTEOSARCOMA; PRIMARY TUMOR; PROSTATE CARCINOMA; PROTEIN BLOOD LEVEL; SOFT TISSUE SARCOMA; TUMOR CELL LINE;

EID: 79952202792     PISSN: 16878450     EISSN: 16878469     Source Type: Journal    
DOI: 10.1155/2010/135354     Document Type: Article

References (35)

1. Broudy V. C., Lin N. L., Kaushansky K., Thrombopoietin (c-mpl ligand) acts synergistically with erythropoietin, stem cell factor, and interleukin-11 to enhance murine megakaryocyte colony growth and increases megakaryocyte ploidy in vitro Blood 1995 85 7 1719 1726
2. de Sauvage F. J., Carver-Moore K., Luoh S.-M., Ryan A., Dowd M., Eaton D. L., Moore M. W., Physiological regulation of early and late stages of megakaryocyto (Pubitemid 26059523)
3. Deutsch V. R., Tomer A., Megakaryocyte development and platelet production British Journal of Haematology 2006 134 5 453 466 (Pubitemid 44141711)
4. Kaushansky K., Broudy V. C., Lin N., Jorgensen M. J., McCarty J., Fox N., Zucker- Franklin D., Lofton-Day C., Thrombopoietin, the Mpl ligand, is essential for full megakaryocyte development Proceedings of the National Academy of Sciences of the United States of America 1995 92 8 3234 3238
5. Kuter D. J., Rosenberg R. D., Appearance of a megakaryocyte growth-promoting activity, megapoietin, during acute thrombocytopenia in the rabbit Blood 1994 84 5 1464 1472 (Pubitemid 24273014)
6. Peeters K., Stassen J.-M., Collen D., Van Geet C., Freson K., Emerging treatments for thrombocytopenia: increasing platelet production Drug Discovery Today 2008 13 17-18 798 806
7. Ballem P. J., Belzberg A., Devine D. V., Lyster D., Spruston B., Chambers H., Doubroff P., Mikulash K., Kinetic studies of the mechanism of thrombocytopenia in patients with human immunodeficiency virus infection The New England Journal of Medicine 1992 327 25 1779 1784
8. Lawrence S. P., Lezotte D. C., Durham J. D., Kumpe D. A., Everson G. T., Bilir B. M., Course of thrombocytopenia of chronic liver disease after transjugular intrahepatic portosystemic shunts (TIPS). A retrospective analysis Digestive Diseases and Sciences 1995 40 7 1575 1580
9. Lazarus A. H., Ellis J., Semple J. W., Mody M., Crow A. R., Freedman J., Comparison of platelet immunity in patients with SLE and with ITP Transfusion Science 2000 22 1-2 19 27 (Pubitemid 30195842)
10. Mittelman M., Platelet function in the myelodysplastic syndromes International Journal of Hematology 2000 71 2 95 98
11. Elting L. S., Rubenstein E. B., Martin C. G., Kurtin D., Rodriguez S., Laiho E., Kanesan K., Cantor S. B., Benjamin R. S., Incidence, cost, and outcomes of bleeding and chemotherapy dose modificaton among solid tumor patients with chemotherapy-induced thrombocytopenia Journal of Clinical Oncology 2001 19 4 1137 1146 (Pubitemid 32176291)
12. Jenkins J. M., Williams D., Deng Y., Uhl J., Kitchen V., Collins D., Erickson-Miller C. L., Phase 1 clinical study of eltrombopag, an oral, nonpeptide thrombopoietin receptor agonist Blood 2007 109 11 4739 4741 (Pubitemid 46827766)
13. Broudy V. C., Lin N. L., AMG531 stimulates megakaryopoiesis in vitro by binding to Mpl Cytokine 2004 25 2 52 60 (Pubitemid 38018897)
14. Erickson-Miller C. L., DelOrme E., Tian S.-S., Hopson C. B., Landis A. J., Valoret E. I., Sellers T. S., Rosen J., Miller S. G., Luengo J. I., Duffy K. J., Jenkins J. M., Preclinical activity of eltrombopag (SB-497115), an oral, nonpeptide thrombopoietin receptor agonist Stem Cells 2009 27 2 424 430
15. Erhardt J. A., Erickson-Miller C. L., Aivado M., Abboud M., Pillarisetti K., Toomey J. R., Comparative analyses of the small molecule thrombopoietin receptor agonist eltrombopag and thrombopoietin on in vitro platelet function Experimental Hematology 2009 37 9 1030 1037
16. Merchionne F., Dammacco F., Biological functions and therapeutic use of erythropoiesis-stimulating agents: perplexities and perspectives British Journal of Haematology 2009 146 2 127 141
17. Newland A. M., Black C. D., Tumor progression associated with erythropoiesis-stimulating agents Annals of Pharmacotherapy 2008 42 12 1865 1870
18. Wetzler M., Bernstein S. H., Baumann H., Fries K. M., Stewart C., Blumenson L., Baer M. R., Herzig G. P., Bloomfield C. D., Slack J. L., Expression and function of the megakaryocyte growth and development factor receptor in acute myeloid leukemia blasts Leukemia and Lymphoma 1998 30 5-6 415 431 (Pubitemid 28393676)
19. Motoji T., Takanashi M., Motomura S., Yan-Hua W., Shiozaki H., Aoyama M., Mizoguchi H., Growth stimulatory effect of thrombopoietin on the blast cells of acute myelogenous leukaemia British Journal of Haematology 1996 94 3 513 516 (Pubitemid 26284077)
20. Murayama T., Imoto S., Natazuka T., Chihara K., Matsui T., Proliferative reaction of myelogenous leukemia cells with cytokines G-CSF, GM-CSF, M-CSF, SCF and TPO Leukemia Research 1998 22 6 557 560 (Pubitemid 28327457)
21. Tafuri A., Lemoli R. M., Petrucci M. T., Ricciardi M. R., Fogli M., Bonsi L., Ariola C., Strippoli P., Gregorj C., Petti M. C., Tura S., Mandelli F., Bagnara G. P., Thrombopoietin and interleukin 11 have different modulatory effects on cell cycle and programmed cell death in primary acute myeloid leukemia cells Experimental Hematology 1999 27 8 1255 1263 (Pubitemid 29347474)
22. Will B., Kawahara M., Luciano J. P., Bruns I., Parekh S., Erickson-Miller C. L., Aivado M. A., Verma A., Steidl U., Effect of the nonpeptide thrombopoietin receptor agonist Eltrombopag on bone marrow cells from patients with acute myeloid leukemia and myelodysplastic syndrome Blood 2009 114 18 3899 3908
23. Erickson-Miller C. L., Kirchner J., Aivado M., May R., Payne P., Chadderton A., Reduced proliferation of non-megakaryocytic acute myelogenous leukemia and other leukemia and lymphoma cell lines in response to eltrombopag Leukemia Research 2010 34 9 1224 1231
24. Mavroudi I., Pyrovolaki K., Pavlaki K., Kozana A., Psyllaki M., Kalpadakis C., Pontikoglou C., Papadaki H. A., Effect of the nonpeptide thrombopoietin receptor agonist eltrombopag on megakaryopoiesis of patients with lower risk myelodysplastic syndrome Leukemia Research 2010. In Press
25. Erickson-Miller C. L., Pillarisetti K., Kirchner J., Low or undetectable TPO receptor expression in malignant tissue and cell lines derived from breast, lung, and ovary., submitted
26. Irizarry R. A., Hobbs B., Collin F., Beazer-Barclay Y. D., Antonellis K. J., Scherf U., Speed T. P., Exploration, normalization, and summaries of high density oligonucleotide array probe level data Biostatistics 2003 4 2 249 264
27. Stroncek D. F., Rebulla P., Platelet transfusions The Lancet 2007 370 9585 427 438 (Pubitemid 47189674)
28. Tvri J., Pirker R., Tmr J., Ostoros G., Kovcs G., Dme B., Erythropoietin in cancer: an update Current Molecular Medicine 2008 8 6 481 491
29. Arcasoy M. O., Erythropoiesis-stimulating agent use in cancer: preclinical and clinical perspectives Clinical Cancer Research 2008 14 15 4685 4690
30. Sinclair A. M., Todd M. D., Forsythe K., Knox S. J., Elliott S., Begley C. G., Expression and function of erythropoietin receptors in tumors: implications for the use of erythropoiesis-stimulating agents in cancer patients Cancer 2007 110 3 477 488 (Pubitemid 47106135)
31. Werner H., Bruchim I., The insulin-like growth factor-I receptor as an oncogene Archives of Physiology and Biochemistry 2009 115 2 58 71
32. Samani A. A., Yakar S., LeRoith D., Brodt P., The role of the IGF system in cancer growth and metastasis: overview and recent insights Endocrine Reviews 2007 28 1 20 47 (Pubitemid 46220849)
33. Sotiriou C., Pusztai L., Gene-expression signatures in breast cancer The New England Journal of Medicine 2009 360 8 752 800
34. Sinclair A. M., Rogers N., Busse L., Archibeque I., Brown W., Kassner P. D., Watson J. E. V., Arnold G. E., Nguyen K. C. Q., Powers S., Elliott S., Erythropoietin receptor transcription is neither elevated nor predictive of surface expression in human tumour cells British Journal of Cancer 2008 98 6 1059 1067 (Pubitemid 351399799)
35. Laugsch M., Metzen E., Svensson T., Depping R., Jelkmann W., Lack of functional erythropoietin receptors of cancer cell lines International Journal of Cancer 2008 122 5 1005 1011 (Pubitemid 351213997)