Dehydron analysis: Quantifying the effect of hydrophobic groups on the strength and stability of hydrogen bonds

Advances in Experimental Medicine and Biology

Volumn 680, Issue , 2010, Pages 473-479

  Fraser, Christopher M ^b   Fernández, Ariel ^b   Scott, L Ridgway ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b NONE

Author keywords

Dehydron; Drug design; Hydrogen bond; Hydrophobic; Solvation

Indexed keywords

ABELSON KINASE; IMATINIB; PROTEIN TYROSINE KINASE INHIBITOR; STEM CELL FACTOR RECEPTOR; UNCLASSIFIED DRUG; WBZ 4; LIGAND; PROTEIN;

BINDING AFFINITY; CARDIOTOXICITY; CONFERENCE PAPER; DEHYDRON; DRUG BINDING SITE; DRUG DESIGN; GASTROINTESTINAL STROMAL TUMOR; GASTROINTESTINAL TUMOR; HUMAN; HYDROGEN BOND; LIGAND BINDING; MATHEMATICAL ANALYSIS; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; ALGORITHM; ARTICLE; BIOLOGY; CHEMICAL PHENOMENA; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; PROTEIN STABILITY;

ALGORITHMS; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; DRUG DESIGN; HYDROGEN BONDING; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIGANDS; MODELS, MOLECULAR; PROTEIN STABILITY; PROTEINS;

EID: 79952199844     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4419-5913-3_53     Document Type: Conference Paper

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