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Volumn 39, Issue 3, 2011, Pages 518-526

Endotoxin tolerance of adrenal gland: Attenuation of corticosterone production in response to lipopolysaccharide and adrenocorticotropic hormone

Author keywords

adrenal gland; adrenocorticotropic hormone; corticosteroid; lipopolysaccharide; rechallenge; sepsis

Indexed keywords

CORTICOTROPIN; ENDOTOXIN; LIPOPOLYSACCHARIDE; TOLL LIKE RECEPTOR 4;

EID: 79952190267     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e318206b980     Document Type: Article
Times cited : (15)

References (47)
  • 1
    • 0036805791 scopus 로고    scopus 로고
    • Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress
    • DOI 10.1016/S0022-3999(02)00429-4, PII S0022399902004294
    • Tsigos C, Chrousos GP: Hypothalamicpituitary- adrenal axis, neuroendocrine factors and stress. J Psychosom Res 2002; 53: 865-871. (Pubitemid 35282615)
    • (2002) Journal of Psychosomatic Research , vol.53 , Issue.4 , pp. 865-871
    • Tsigos, C.1    Chrousos, G.P.2
  • 2
  • 3
    • 1842530882 scopus 로고    scopus 로고
    • Clinical review: Corticotherapy in sepsis
    • DOI 10.1186/cc2374
    • Prigent H, Maxime V, Annane D: Clinical review: Corticotherapy in sepsis. Crit Care: 2004; 8:122-129. (Pubitemid 38436420)
    • (2004) Critical Care , vol.8 , Issue.2 , pp. 122-129
    • Prigent, H.1    Maxime, V.2    Annane, D.3
  • 4
    • 38049015993 scopus 로고    scopus 로고
    • The hypothalamic-pituitary-adrenal axis in critical illness
    • Venkataraman S, Munoz R, Candido C, et al: The hypothalamic-pituitary- adrenal axis in critical illness. Rev Endocr Metab Disord 2007; 8:365-373.
    • (2007) Rev Endocr Metab Disord , vol.8 , pp. 365-373
    • Venkataraman, S.1    Munoz, R.2    Candido, C.3
  • 5
    • 77951863360 scopus 로고    scopus 로고
    • Adrenal insufficiency: Etiology, diagnosis and treatment
    • Neary N, Nieman L: Adrenal insufficiency: Etiology, diagnosis and treatment. Curr Opin Endocrinol Diabetes Obes 2010; 17:217-223.
    • (2010) Curr Opin Endocrinol Diabetes Obes , vol.17 , pp. 217-223
    • Neary, N.1    Nieman, L.2
  • 6
    • 23744502648 scopus 로고    scopus 로고
    • Hypothalamic-pituitary dysfunction in critically ill patients with traumatic and nontraumatic brain injury
    • DOI 10.1007/s00134-005-2689-y
    • Dimopoulou I, Tsagarakis S: Hypothalamicpituitary dysfunction in critically ill patients with traumatic and nontraumatic brain injury. Intensive Care Med 2005; 31:1020-1028. (Pubitemid 41125332)
    • (2005) Intensive Care Medicine , vol.31 , Issue.8 , pp. 1020-1028
    • Dimopoulou, I.1    Tsagarakis, S.2
  • 7
    • 33645962481 scopus 로고    scopus 로고
    • Adrenal insufficiency in patients with cirrhosis, severe sepsis and septic shock
    • Tsai MH, Peng YS, Chen YC, et al: Adrenal insufficiency in patients with cirrhosis, severe sepsis and septic shock. Hepatology 2006; 43:673-681.
    • (2006) Hepatology , vol.43 , pp. 673-681
    • Tsai, M.H.1    Peng, Y.S.2    Chen, Y.C.3
  • 9
    • 45149105776 scopus 로고    scopus 로고
    • Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: Consensus statements from an international task force by the American College of Critical Care Medicine
    • Marik PE, Pastores SM, Annane D, et al: Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: Consensus statements from an international task force by the American College of Critical Care Medicine. Crit Care Med 2008; 36:1937-1949.
    • (2008) Crit Care Med , vol.36 , pp. 1937-1949
    • Marik, P.E.1    Pastores, S.M.2    Annane, D.3
  • 11
    • 0037451929 scopus 로고    scopus 로고
    • The epidemiology of sepsis in the United States from 1979 through 2000
    • DOI 10.1056/NEJMoa022139
    • Martin GS, Mannino DM, Eaton S, et al: The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med 2003; 348:1546-1554. (Pubitemid 36437931)
    • (2003) New England Journal of Medicine , vol.348 , Issue.16 , pp. 1546-1554
    • Martin, G.S.1    Mannino, D.M.2    Eaton, S.3    Moss, M.4
  • 12
    • 0030322237 scopus 로고    scopus 로고
    • Cytokines as mediators in the pathogenesis of septic shock
    • Dinarello CA: Cytokines as mediators in the pathogenesis of septic shock. Curr Top Microbiol Immunol 1996; 216:134-165.
    • (1996) Curr Top Microbiol Immunol , vol.216 , pp. 134-165
    • Dinarello, C.A.1
  • 13
    • 0037224508 scopus 로고    scopus 로고
    • Endotoxin and the hypothalamo-pituitary-adrenal (HPA) axis
    • DOI 10.1179/096805103125001298
    • Beishuizen A, Thijs LG: Endotoxin and the hypothalamo-pituitary-adrenal (HPA) axis. J Endotoxin Res 2003; 9:3-24. (Pubitemid 36322480)
    • (2003) Journal of Endotoxin Research , vol.9 , Issue.1 , pp. 3-24
    • Beishuizen, A.1    Thijs, L.G.2
  • 14
    • 0027169378 scopus 로고
    • Endotoxin-induced corticotropin-releasing hormone gene expression in the hypothalamic paraventricular nucleus is mediated centrally by interleukin-1
    • DOI 10.1210/en.133.2.815
    • Kakucska I, Qi Y, Clark BD, et al: Endotoxininduced corticotropin- releasing hormone gene expression in the hypothalamic paraventricular nucleus is mediated centrally by interleukin-1. Endocrinology 1993; 133: 815-821. (Pubitemid 23238897)
    • (1993) Endocrinology , vol.133 , Issue.2 , pp. 815-821
    • Kakucska, I.1    Qi, Y.2    Clark, B.D.3    Lechan, R.M.4
  • 15
    • 0028866679 scopus 로고
    • Early hypothalamic activation of combined Fos and CRH41 immunoreactivity and of CRH41 release in push-pull cannulated rats after systemic endotoxin challenge
    • Givalois L, Siaud P, Mekaouche M, et al: Early hypothalamic activation of combined Fos and CRH41 immunoreactivity and of CRH41 release in push-pull cannulated rats after systemic endotoxin challenge. Mol Chem Neuropathol 1995; 26:171-186.
    • (1995) Mol Chem Neuropathol , vol.26 , pp. 171-186
    • Givalois, L.1    Siaud, P.2    Mekaouche, M.3
  • 16
    • 42449103563 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase contributes to lipopolysaccharide- induced activation of corticotropin-releasing hormone synthesizing neurons in the hypothalamic paraventricular nucleus
    • DOI 10.1210/en.2007-1478
    • Singru PS, Sánchez E, Acharya R, et al: Mitogen- activated protein kinase contributes to lipopolysaccharide- induced activation of corticotropin- releasing hormone synthesizing neurons in the hypothalamic paraventricular nucleus. Endocrinology 2008; 149:2283-2292. (Pubitemid 351574481)
    • (2008) Endocrinology , vol.149 , Issue.5 , pp. 2283-2292
    • Singru, P.S.1    Sanchez, E.2    Acharya, R.3    Fekete, C.4    Lechan, R.M.5
  • 17
    • 0026580609 scopus 로고
    • Lipopolysaccharide is able to bypass corticotrophinreleasing factor in affecting plasma ACTH and corticosterone levels: Evidence from rats with lesions of the paraventricular nucleus
    • Elenkov IJ, Kovács K, Kiss J, et al: Lipopolysaccharide is able to bypass corticotrophinreleasing factor in affecting plasma ACTH and corticosterone levels: Evidence from rats with lesions of the paraventricular nucleus. J Endocrinol 1992; 133:231-236.
    • (1992) J Endocrinol , vol.133 , pp. 231-236
    • Elenkov, I.J.1    Kovács, K.2    Kiss, J.3
  • 18
    • 0026958591 scopus 로고
    • CRFdependent and CRF-independent mechanisms involved in hypophysial-adrenal system activation by bacterial endotoxin
    • Elenkov IJ, Kiss J, Stark E, et al: CRFdependent and CRF-independent mechanisms involved in hypophysial-adrenal system activation by bacterial endotoxin. Acta Physiol Hung 1992; 79:355-363.
    • (1992) Acta Physiol Hung , vol.79 , pp. 355-363
    • Elenkov, I.J.1    Kiss, J.2    Stark, E.3
  • 19
    • 0034255366 scopus 로고    scopus 로고
    • Interleukin-6 is an essential, corticotropin-releasing hormone-independent stimulator of the adrenal axis during immune system activation
    • DOI 10.1073/pnas.97.16.9317
    • Bethin KE, Vogt SK, Muglia LJ: Interleukin- 6 is an essential, corticotropin-releasing hormone-independent stimulator of the adrenal axis during immune system activation. Proc Nat Acad Sci USA 2000; 97:9317-9322. (Pubitemid 30626716)
    • (2000) Proceedings of the National Academy of Sciences of the United States of America , vol.97 , Issue.16 , pp. 9317-9322
    • Bethin, K.E.1    Vogt, S.K.2    Muglia, L.J.3
  • 20
    • 14244252223 scopus 로고    scopus 로고
    • Lipopolysaccharide directly stimulates cortisol secretion by human adrenal cells by a cyclooxygenase-dependent mechanism
    • DOI 10.1210/en.2004-0882
    • Vakharia K, Hinson JP: Lipopolysaccharide directly stimulates cortisol secretion by human adrenal cells by a cyclooxygenasedependent mechanism. Endocrinology 2005; 146:1398-1402. (Pubitemid 40289328)
    • (2005) Endocrinology , vol.146 , Issue.3 , pp. 1398-1402
    • Vakharia, K.1    Hinson, J.P.2
  • 21
    • 24944441771 scopus 로고    scopus 로고
    • Response of rat fasciculata-reticularis cells in primary culture to bacterial lipopolysaccharide
    • Enríquez de Salamanca A, García R: Response of rat fasciculata-reticularis cells in primary culture to bacterial lipopolysaccharide. Microbes Infect 2005; 7:1077-1086.
    • (2005) Microbes Infect , vol.7 , pp. 1077-1086
    • Enríquez De Salamanca, A.1    García, R.2
  • 22
    • 0000424296 scopus 로고
    • Development of tolerance to typhoid bacterial pyrogen and its abolition by reticulo-endothelial blockade
    • Beeson PB: Development of tolerance to typhoid bacterial pyrogen and its abolition by reticulo-endothelial blockade. Proc Soc Exp Biol Med 1946; 61:248-250.
    • (1946) Proc Soc Exp Biol Med , vol.61 , pp. 248-250
    • Beeson, P.B.1
  • 23
    • 0014454793 scopus 로고
    • Endotoxins and the immune response
    • Neter E: Endotoxins and the immune response. Curr Top Microbiol Immunol 1969; 47:82-124.
    • (1969) Curr Top Microbiol Immunol , vol.47 , pp. 82-124
    • Neter, E.1
  • 24
    • 0036159842 scopus 로고    scopus 로고
    • Endotoxin tolerance: A review
    • West MA, Heagy W: Endotoxin tolerance: A review. Crit Care Med 2002; 30:S64-S73. (Pubitemid 34131164)
    • (2002) Critical Care Medicine , vol.30 , Issue.1 SUPPL. B
    • West, M.A.1    Heagy, W.2
  • 25
    • 33645829090 scopus 로고    scopus 로고
    • Cecal ligation and puncture in rats interrupts the circadian rhythms of corticosterone and adrenocortical responsiveness to adrenocorticotrophic hormone
    • Carlson DE, Chiu WC, Scalea TM: Cecal ligation and puncture in rats interrupts the circadian rhythms of corticosterone and adrenocortical responsiveness to adrenocorticotrophic hormone. Crit Care Med 2006; 34: 1178-1184.
    • (2006) Crit Care Med , vol.34 , pp. 1178-1184
    • Carlson, D.E.1    Chiu, W.C.2    Scalea, T.M.3
  • 26
    • 30044446207 scopus 로고    scopus 로고
    • Differences between the growth regulatory pathways in primary rat adrenal cells and mouse tumor cell line
    • DOI 10.1016/j.mce.2005.10.001, PII S0303720705003370
    • Mattos GE, Lotfi CF: Differences between the growth regulatory pathways in primary rat adrenal cells and mouse tumor cell line. Mol Cell Endocrinol 2005; 245:31-42. (Pubitemid 43049743)
    • (2006) Molecular and Cellular Endocrinology , vol.245 , Issue.1-2 , pp. 31-42
    • Mattos, G.E.1    Lotfi, C.F.P.2
  • 27
    • 0023619677 scopus 로고
    • A study of some variables in a tetrazolium dye (MTT) based assay for cell growth and chemosensitivity
    • Twentyman PR, Luscombe M: A study of some variables in a tetrazolium dye (MTT) based assay for cell growth and chemosensitivity. Br J Cancer 1987; 56:279-285. (Pubitemid 17158816)
    • (1987) British Journal of Cancer , vol.56 , Issue.3 , pp. 279-285
    • Twentyman, P.R.1    Luscombe, M.2
  • 28
    • 77950605510 scopus 로고    scopus 로고
    • Glucocorticoids suppress cystathionine gamma-lyase expression and H2S production in lipopolysaccharide- treated macrophages
    • Zhu XY, Liu SJ, Liu YJ, et al: Glucocorticoids suppress cystathionine gamma-lyase expression and H2S production in lipopolysaccharide- treated macrophages. Cell Mol Life Sci 2010; 67:1119-1132.
    • (2010) Cell Mol Life Sci , vol.67 , pp. 1119-1132
    • Zhu, X.Y.1    Liu, S.J.2    Liu, Y.J.3
  • 29
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • Livak KJ, Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001; 25:402-408. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 30
    • 33646590972 scopus 로고    scopus 로고
    • Toll-like receptor 4 plays a crucial role in the immune-adrenal response to systemic in- flammatory response syndrome
    • Zacharowski K, Zacharowski PA, Koch A, et al: Toll-like receptor 4 plays a crucial role in the immune-adrenal response to systemic in- flammatory response syndrome. Proc Nat Acad Sci USA 2006; 103:6392-6397.
    • (2006) Proc Nat Acad Sci USA , vol.103 , pp. 6392-6397
    • Zacharowski, K.1    Zacharowski, P.A.2    Koch, A.3
  • 32
    • 34548412080 scopus 로고    scopus 로고
    • Transcriptional regulation of adrenocortical steroidogenic gene expression
    • DOI 10.1080/03602530701498828, PII 781829433
    • Sewer MB, Dammer EB, Jagarlapudi S: Transcriptional regulation of adrenocortical steroidogenic gene expression. Drug Metab Rev 2007; 39:371-388. (Pubitemid 47364558)
    • (2007) Drug Metabolism Reviews , vol.39 , Issue.2-3 , pp. 371-388
    • Sewer, M.B.1    Dammer, E.B.2    Jagarlapudi, S.3
  • 33
    • 58849120086 scopus 로고    scopus 로고
    • Adrenal insufficiency in septic shock
    • vii
    • Maxime V, Lesur O, Annane D: Adrenal insufficiency in septic shock. Clin Chest Med 2009; 30:17-27, vii.
    • (2009) Clin Chest Med , vol.30 , pp. 17-27
    • Maxime, V.1    Lesur, O.2    Annane, D.3
  • 34
    • 0036275133 scopus 로고    scopus 로고
    • Adrenal insufficiency in critically ill patients with human immunodeficiency virus
    • Marik PE, Kiminyo K, Zaloga GP: Adrenal insufficiency in critically ill patients with human immunodeficiency virus. Crit Care Med 2002; 30:1267-1273. (Pubitemid 34620970)
    • (2002) Critical Care Medicine , vol.30 , Issue.6 , pp. 1267-1273
    • Marik, P.E.1    Kiminyo, K.2    Zaloga, G.P.3
  • 35
    • 0037250881 scopus 로고    scopus 로고
    • Adrenal insufficiency during septic shock
    • DOI 10.1097/00003246-200301000-00022
    • Marik PE, Zaloga GP: Adrenal insufficiency during septic shock. Crit Care Med 2003; 31:141-145. (Pubitemid 36151163)
    • (2003) Critical Care Medicine , vol.31 , Issue.1 , pp. 141-145
    • Marik, P.E.1    Zaloga, G.P.2
  • 37
    • 70349559403 scopus 로고    scopus 로고
    • Endotoxin tolerance: New mechanisms, molecules and clinical significance
    • Biswas SK, Lopez-Collazo E: Endotoxin tolerance: New mechanisms, molecules and clinical significance. Trends Immunol 2009; 30:475-487.
    • (2009) Trends Immunol , vol.30 , pp. 475-487
    • Biswas, S.K.1    Lopez-Collazo, E.2
  • 38
    • 0034043956 scopus 로고    scopus 로고
    • Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mouse macrophages: Dysregulation of cytokine, chemokine, and Toll-like receptor 2 and 4 gene expression
    • Medvedev AE, Kopydlowski KM, Vogel SN: Inhibition of lipopolysaccharide- induced signal transduction in endotoxin-tolerized mouse macrophages: Dysregulation of cytokine, chemokine, and toll-like receptor 2 and 4 gene expression. J Immunol 2000; 164: 5564-5574. (Pubitemid 30389795)
    • (2000) Journal of Immunology , vol.164 , Issue.11 , pp. 5564-5574
    • Medvedev, A.E.1    Kopydlowski, K.M.2    Vogel, S.N.3
  • 39
    • 0036319517 scopus 로고    scopus 로고
    • A variety of microbial components induce tolerance to lipopolysaccharide by differentially affecting MyD88-dependent and -independent pathways
    • Sato S, Takeuchi O, Fujita T, et al: A variety of microbial components induce tolerance to lipopolysaccharide by differentially affecting MyD88-dependent and -independent pathways. Int Immunol 2002; 14:783-791. (Pubitemid 34814639)
    • (2002) International Immunology , vol.14 , Issue.7 , pp. 783-791
    • Sato, S.1    Takeuchi, O.2    Fujita, T.3    Tomizawa, H.4    Takeda, K.5    Akira, S.6
  • 40
    • 34548489609 scopus 로고    scopus 로고
    • Lipopolysaccharide primes macrophages to increase nitric oxide production in response to Staphylococcus Aureus
    • DOI 10.1016/j.imlet.2007.06.007, PII S0165247807001460
    • Zhu X, Liu Y, Liu S, et al: Lipopolysaccharide primes macrophages to increase nitric oxide production in response to Staphylococcus aureus. Immunol Lett 2007; 112:75-81. (Pubitemid 47379850)
    • (2007) Immunology Letters , vol.112 , Issue.2 , pp. 75-81
    • Zhu, X.1    Liu, Y.2    Liu, S.3    Diao, F.4    Xu, R.5    Ni, X.6
  • 41
    • 2442485789 scopus 로고    scopus 로고
    • Differential regulation of cytokine and chemokine production in lipopolysaccharide-induced tolerance and priming
    • DOI 10.1016/j.cyto.2004.02.011, PII S1043466604000729
    • Peck OM, Williams DL, Breuel KF, et al: Differential regulation of cytokine and chemokine production in lipopolysaccharide- induced tolerance and priming. Cytokine 2004; 26:202-208. (Pubitemid 38639748)
    • (2004) Cytokine , vol.26 , Issue.5 , pp. 202-208
    • Peck, O.M.1    Williams, D.L.2    Breuel, K.F.3    Kalbfleisch, J.H.4    Fan, H.5    Tempel, G.E.6    Teti, G.7    Cook, J.A.8
  • 42
    • 2442442903 scopus 로고    scopus 로고
    • Staphylococcus aureus and lipopolysaccharide induce homologous tolerance but heterologous priming: Role of interferon-gamma
    • Peck OM, Fan H, Tempel GE, et al: Staphylococcus aureus and lipopolysaccharide induce homologous tolerance but heterologous priming: Role of interferon-gamma. Shock 2004; 21:254-260.
    • (2004) Shock , vol.21 , pp. 254-260
    • Peck, O.M.1    Fan, H.2    Tempel, G.E.3
  • 43
    • 0035871626 scopus 로고    scopus 로고
    • Induction of cross-tolerance by lipopolysaccharide and highly purified lipoteichoic acid via different toll-like receptors independent of paracrine mediators
    • Lehner MD, Morath S, Michelsen KS, et al: Induction of cross-tolerance by lipopolysaccharide and highly purified lipoteichoic acid via different Toll-like receptors independent of paracrine mediators. J Immunol 2001; 166:5161-5167. (Pubitemid 32280731)
    • (2001) Journal of Immunology , vol.166 , Issue.8 , pp. 5161-5167
    • Lehner, M.D.1    Morath, S.2    Michelsen, K.S.3    Schumann, R.R.4    Hartung, T.5
  • 44
    • 2342430991 scopus 로고    scopus 로고
    • Molecular mechanisms of endotoxin tolerance
    • Fan H, Cook JA: Molecular mechanisms of endotoxin tolerance. J Endotoxin Res 2004; 10:71-84.
    • (2004) J Endotoxin Res , vol.10 , pp. 71-84
    • Fan, H.1    Cook, J.A.2
  • 45
    • 50549102070 scopus 로고    scopus 로고
    • Monocytes from cystic fibrosis patients are locked in an LPS tolerance state: Downregulation of TREM-1 as putative underlying mechanism
    • Del Fresno C, Gómez-Piñ a V, Lores V, et al: Monocytes from cystic fibrosis patients are locked in an LPS tolerance state: downregulation of TREM-1 as putative underlying mechanism. PLoS One 2008; 3:e2667.
    • (2008) PLoS One , vol.3
    • Del Fresno, C.1    Gómez-Piña, V.2    Lores, V.3
  • 46
    • 38449086201 scopus 로고    scopus 로고
    • Induction of IRAK-M is associated with lipopolysaccharide tolerance in a human endotoxemia model
    • Van't Veer C, Van den Pangaart PS, Van Zoelen MA, et al: Induction of IRAK-M is associated with lipopolysaccharide tolerance in a human endotoxemia model, J Immunol, 2007, 179, 7110-7120.
    • (2007) J Immunol , vol.179 , pp. 7110-7120
    • Van'T Veer, C.1    Van Den Pangaart, P.S.2    Van Zoelen, M.A.3
  • 47
    • 4344574905 scopus 로고    scopus 로고
    • Science review: Mechanisms of impaired adrenal function in sepsis and molecular actions of glucocorticoids
    • DOI 10.1186/cc2878
    • Prigent H, Maxime V, Annane D: Science review: Mechanisms of impaired adrenal function in sepsis and molecular actions of glucocorticoids. Crit Care 2004; 8:243-252 (Pubitemid 39144714)
    • (2004) Critical Care , vol.8 , Issue.4 , pp. 243-252
    • Prigent, H.1    Maxime, V.2    Annane, D.3


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