메뉴 건너뛰기




Volumn 6, Issue 7, 2010, Pages 2386-2393

Modulation of osteogenic properties of biodegradable polymer/extracellular matrix scaffolds generated with a flow perfusion bioreactor

Author keywords

Bone tissue engineering; Cell matrix signals; Electrospun polymer scaffold; Mesenchymal stem cell; Microenvironment

Indexed keywords

BIODEGRADABLE POLYMERS; CALCIUM; CELL ENGINEERING; CELL PROLIFERATION; DEPOSITION; ENZYME ACTIVITY; FLOWCHARTING; PHOSPHATASES; POLYMER MATRIX COMPOSITES; SCAFFOLDS (BIOLOGY); STEM CELLS;

EID: 77955885763     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2010.01.011     Document Type: Article
Times cited : (68)

References (29)
  • 2
    • 84934436472 scopus 로고    scopus 로고
    • Modulation of cell differentiation in bone tissue engineering constructs cultured in a bioreactor
    • Holtorf HL, Jansen JA, Mikos AG. Modulation of cell differentiation in bone tissue engineering constructs cultured in a bioreactor. Adv Exp Med Biol 2006;585:225-41.
    • (2006) Adv. Exp. Med. Biol. , vol.585 , pp. 225-241
    • Holtorf, H.L.1    Jansen, J.A.2    Mikos, A.G.3
  • 3
    • 15244353095 scopus 로고    scopus 로고
    • Multilineage differentiation of human mesenchymal stem cells in a three-dimensional nanofibrous scaffold
    • DOI 10.1016/j.biomaterials.2005.01.002, PII S0142961205000037
    • Li WJ, Tuli R, Huang X, Laquerriere P, Tuan RS. Multilineage differentiation of human mesenchymal stem cells in a three-dimensional nanofibrous scaffold. Biomaterials 2005;26(25):5158-66. (Pubitemid 40387839)
    • (2005) Biomaterials , vol.26 , Issue.25 , pp. 5158-5166
    • Li, W.-J.1    Tuli, R.2    Huang, X.3    Laquerriere, P.4    Tuan, R.S.5
  • 5
    • 13944270566 scopus 로고    scopus 로고
    • Flow perfusion culture induces the osteoblastic differentiation of marrow stroma cell-scaffold constructs in the absence of dexamethasone
    • Holtorf HL, Jansen JA, Mikos AG. Flow perfusion culture induces the osteoblastic differentiation of marrow stroma cell-scaffold constructs in the absence of dexamethasone. J Biomed Mater Res A 2005;72(3):326-34.
    • (2005) J. Biomed. Mater. Res. A , vol.72 , Issue.3 , pp. 326-334
    • Holtorf, H.L.1    Jansen, J.A.2    Mikos, A.G.3
  • 6
    • 4444263807 scopus 로고    scopus 로고
    • Effect of bone extracellular matrix synthesized in vitro on the osteoblastic differentiation of marrow stromal cells
    • Datta N, Holtorf HL, Sikavitsas VI, Jansen JA, Mikos AG. Effect of bone extracellular matrix synthesized in vitro on the osteoblastic differentiation of marrow stromal cells. Biomaterials 2005;26(9):971-7.
    • (2005) Biomaterials , vol.26 , Issue.9 , pp. 971-977
    • Datta, N.1    Holtorf, H.L.2    Sikavitsas, V.I.3    Jansen, J.A.4    Mikos, A.G.5
  • 7
    • 33644517215 scopus 로고    scopus 로고
    • In vitro generated extracellular matrix and fluid shear stress synergistically enhance 3D osteoblastic differentiation
    • Datta N, Pham QP, Sharma U, Sikavitsas VI, Jansen JA, Mikos AG. In vitro generated extracellular matrix and fluid shear stress synergistically enhance 3D osteoblastic differentiation. Proc Natl Acad Sci USA 2006;103(8):2488-93.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , Issue.8 , pp. 2488-2493
    • Datta, N.1    Pham, Q.P.2    Sharma, U.3    Sikavitsas, V.I.4    Jansen, J.A.5    Mikos, A.G.6
  • 8
    • 0348015827 scopus 로고    scopus 로고
    • Influence of the in vitro culture period on the in vivo performance of cell/titanium bone tissue-engineered constructs using a rat cranial critical size defect model
    • Sikavitsas VI, van den Dolder J, Bancroft GN, Jansen JA, Mikos AG. Influence of the in vitro culture period on the in vivo performance of cell/titanium bone tissue-engineered constructs using a rat cranial critical size defect model. J Biomed Mater Res A 2003;67(3):944-51.
    • (2003) J. Biomed. Mater. Res. A , vol.67 , Issue.3 , pp. 944-951
    • Sikavitsas, V.I.1    Van Den Dolder, J.2    Bancroft, G.N.3    Jansen, J.A.4    Mikos, A.G.5
  • 10
    • 33750315715 scopus 로고    scopus 로고
    • Electrospun poly (epsilon-caprolactone) microfiber and multilayer nanofiber/microfiber scaffolds: Characterization of scaffolds and measurement of cellular infiltration
    • Pham QP, Sharma U, Mikos AG. Electrospun poly (epsilon-caprolactone) microfiber and multilayer nanofiber/microfiber scaffolds: characterization of scaffolds and measurement of cellular infiltration. Biomacromolecules 2006;7(10):2796-805.
    • (2006) Biomacromolecules , vol.7 , Issue.10 , pp. 2796-2805
    • Pham, Q.P.1    Sharma, U.2    Mikos, A.G.3
  • 11
    • 0037937606 scopus 로고    scopus 로고
    • Design of a flow perfusion bioreactor system for bone tissue-engineering applications
    • Bancroft GN, Sikavitsas VI, Mikos AG. Design of a flow perfusion bioreactor system for bone tissue-engineering applications. Tissue Eng 2003;9(3):549-54.
    • (2003) Tissue Eng. , vol.9 , Issue.3 , pp. 549-554
    • Bancroft, G.N.1    Sikavitsas, V.I.2    Mikos, A.G.3
  • 12
    • 0023729166 scopus 로고
    • Bone formation in vitro by stromal cells obtained from bone marrow of young adult rats
    • Maniatopoulos C, Sodek J, Melcher AH. Bone formation in vitro by stromal cells obtained from bone marrow of young adult rats. Cell Tissue Res 1988;254(2):317-30.
    • (1988) Cell. Tissue Res. , vol.254 , Issue.2 , pp. 317-330
    • Maniatopoulos, C.1    Sodek, J.2    Melcher, A.H.3
  • 13
    • 0030750210 scopus 로고    scopus 로고
    • Differences in dermal analogs influence subsequent pigmentation, epidermal differentiation, basement membrane, and rete ridge formation of transplanted composite skin grafts
    • Medalie DA, Eming SA, Collins ME, Tompkins RG, Yarmush ML, Morgan JR. Differences in dermal analogs influence subsequent pigmentation, epidermal differentiation, basement membrane, and rete ridge formation of transplanted composite skin grafts. Transplantation 1997;64(3):454-65.
    • (1997) Transplantation , vol.64 , Issue.3 , pp. 454-465
    • Medalie, D.A.1    Eming, S.A.2    Collins, M.E.3    Tompkins, R.G.4    Yarmush, M.L.5    Morgan, J.R.6
  • 14
    • 0014154751 scopus 로고
    • Determination of hydroxyproline
    • Stegemann H, Stalder K. Determination of hydroxyproline. Clin Chim Acta 1967;18(2):267-73.
    • (1967) Clin. Chim. Acta , vol.18 , Issue.2 , pp. 267-273
    • Stegemann, H.1    Stalder, K.2
  • 15
    • 0033043139 scopus 로고    scopus 로고
    • Bioreactor cultivation conditions modulate the composition and mechanical properties of tissue-engineered cartilage
    • Vunjak-Novakovic G, Martin I, Obradovic B, Treppo S, Grodzinsky AJ, Langer R, et al. Bioreactor cultivation conditions modulate the composition and mechanical properties of tissue-engineered cartilage. J Orthop Res 1999;17(1):130-8.
    • (1999) J. Orthop. Res. , vol.17 , Issue.1 , pp. 130-138
    • Vunjak-Novakovic, G.1    Martin, I.2    Obradovic, B.3    Treppo, S.4    Grodzinsky, A.J.5    Langer, R.6
  • 16
    • 0022552896 scopus 로고
    • Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue
    • Farndale RW, Buttle DJ, Barrett AJ. Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue. Biochim Biophys Acta 1986;883(2):173-7.
    • (1986) Biochim. Biophys. Acta , vol.883 , Issue.2 , pp. 173-177
    • Farndale, R.W.1    Buttle, D.J.2    Barrett, A.J.3
  • 17
    • 34247561381 scopus 로고    scopus 로고
    • Injectable biodegradable hydrogel composites for rabbit marrow mesenchymal stem cell and growth factor delivery for cartilage tissue engineering
    • Park H, Temenoff JS, Tabata Y, Caplan AI, Mikos AG. Injectable biodegradable hydrogel composites for rabbit marrow mesenchymal stem cell and growth factor delivery for cartilage tissue engineering. Biomaterials 2007;28(21):3217-27.
    • (2007) Biomaterials , vol.28 , Issue.21 , pp. 3217-3227
    • Park, H.1    Temenoff, J.S.2    Tabata, Y.3    Caplan, A.I.4    Mikos, A.G.5
  • 18
    • 69249088910 scopus 로고    scopus 로고
    • Dose effect of dual delivery of vascular endothelial growth factor and bone morphogenetic protein-2 on bone regeneration in a rat critical-size defect model
    • Young S, Patel ZS, Kretlow JD, Murphy MB, Mountziaris PM, Baggett LS, et al. Dose effect of dual delivery of vascular endothelial growth factor and bone morphogenetic protein-2 on bone regeneration in a rat critical-size defect model. Tissue Eng Part A 2009;15(9):2347-62.
    • (2009) Tissue Eng. Part A , vol.15 , Issue.9 , pp. 2347-2362
    • Young, S.1    Patel, Z.S.2    Kretlow, J.D.3    Murphy, M.B.4    Mountziaris, P.M.5    Baggett, L.S.6
  • 19
    • 0031194671 scopus 로고    scopus 로고
    • Characterization of PicoGreen reagent and development of a fluorescence-based solution assay for double-stranded DNA quantitation
    • Singer VL, Jones LJ, Yue ST, Haugland RP. Characterization of PicoGreen reagent and development of a fluorescence-based solution assay for double-stranded DNA quantitation. Anal Biochem 1997;249(2):228-38.
    • (1997) Anal. Biochem. , vol.249 , Issue.2 , pp. 228-238
    • Singer, V.L.1    Jones, L.J.2    Yue, S.T.3    Haugland, R.P.4
  • 20
    • 0003075131 scopus 로고
    • Alkaline phosphatases, routine method
    • Bergmeyer HU, Bergmeyer J, Grassl M, editors, Verlag Chemie
    • Bretaudiere JP, Spillman T. Alkaline phosphatases, routine method. In: Bergmeyer HU, Bergmeyer J, Grassl M, editors. Methods of enzymatic analysis. Verlag Chemie; 1984. p. 75-82.
    • (1984) Methods of Enzymatic Analysis , pp. 75-82
    • Bretaudiere, J.P.1    Spillman, T.2
  • 21
    • 17044418448 scopus 로고    scopus 로고
    • Flow perfusion enhances the calcified matrix deposition of marrow stromal cells in biodegradable nonwoven fiber mesh scaffolds
    • Sikavitsas VI, Bancroft GN, Lemoine JJ, Liebschner MA, Dauner M, Mikos AG. Flow perfusion enhances the calcified matrix deposition of marrow stromal cells in biodegradable nonwoven fiber mesh scaffolds. Ann Biomed Eng 2005;33(1):63-70.
    • (2005) Ann. Biomed. Eng. , vol.33 , Issue.1 , pp. 63-70
    • Sikavitsas, V.I.1    Bancroft, G.N.2    Lemoine, J.J.3    Liebschner, M.A.4    Dauner, M.5    Mikos, A.G.6
  • 22
    • 0344306513 scopus 로고    scopus 로고
    • Effect of flow perfusion on the osteogenic differentiation of bone marrow stromal cells cultured on starch-based three-dimensional scaffolds
    • Gomes ME, Sikavitsas VI, Behravesh E, Reis RL, Mikos AG. Effect of flow perfusion on the osteogenic differentiation of bone marrow stromal cells cultured on starch-based three-dimensional scaffolds. J Biomed Mater Res A 2003;67(1):87-95.
    • (2003) J. Biomed. Mater. Res. A , vol.67 , Issue.1 , pp. 87-95
    • Gomes, M.E.1    Sikavitsas, V.I.2    Behravesh, E.3    Reis, R.L.4    Mikos, A.G.5
  • 23
    • 0345598939 scopus 로고    scopus 로고
    • Mineralized matrix deposition by marrow stromal osteoblasts in 3D perfusion culture increases with increasing fluid shear forces
    • Sikavitsas VI, Bancroft GN, Holtorf HL, Jansen JA, Mikos AG. Mineralized matrix deposition by marrow stromal osteoblasts in 3D perfusion culture increases with increasing fluid shear forces. Proc Natl Acad Sci USA 2003;100(25):14683-8.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , Issue.25 , pp. 14683-14688
    • Sikavitsas, V.I.1    Bancroft, G.N.2    Holtorf, H.L.3    Jansen, J.A.4    Mikos, A.G.5
  • 24
    • 22244450402 scopus 로고    scopus 로고
    • Scaffold mesh size affects the osteoblastic differentiation of seeded marrow stromal cells cultured in a flow perfusion bioreactor
    • Holtorf HL, Datta N, Jansen JA, Mikos AG. Scaffold mesh size affects the osteoblastic differentiation of seeded marrow stromal cells cultured in a flow perfusion bioreactor. J Biomed Mater Res A 2005;74(2):171-80.
    • (2005) J. Biomed. Mater. Res. A , vol.74 , Issue.2 , pp. 171-180
    • Holtorf, H.L.1    Datta, N.2    Jansen, J.A.3    Mikos, A.G.4
  • 25
    • 0025316785 scopus 로고
    • Progressive development of the rat osteoblast phenotype in vitro: Reciprocal relationships in expression of genes associated with osteoblast proliferation and differentiation during formation of the bone extracellular matrix
    • Owen TA, Aronow M, Shalhoub V, Barone LM, Wilming L, Tassinari MS, et al. Progressive development of the rat osteoblast phenotype in vitro: reciprocal relationships in expression of genes associated with osteoblast proliferation and differentiation during formation of the bone extracellular matrix. J Cell Physiol 1990;143(3):420-30.
    • (1990) J. Cell. Physiol. , vol.143 , Issue.3 , pp. 420-430
    • Owen, T.A.1    Aronow, M.2    Shalhoub, V.3    Barone, L.M.4    Wilming, L.5    Tassinari, M.S.6
  • 26
    • 33644907150 scopus 로고    scopus 로고
    • In vitro localization of bone growth factors in constructs of biodegradable scaffolds seeded with marrow stromal cells and cultured in a flow perfusion bioreactor
    • Gomes ME, Bossano CM, Johnston CM, Reis RL, Mikos AG. In vitro localization of bone growth factors in constructs of biodegradable scaffolds seeded with marrow stromal cells and cultured in a flow perfusion bioreactor. Tissue Eng 2006;12(1):177-88.
    • (2006) Tissue Eng. , vol.12 , Issue.1 , pp. 177-188
    • Gomes, M.E.1    Bossano, C.M.2    Johnston, C.M.3    Reis, R.L.4    Mikos, A.G.5
  • 27
    • 0030621987 scopus 로고    scopus 로고
    • In vitro attachment of osteoblast-like cells to osteoceramic materials
    • Keller JC, Collins JG, Niederauer GG, McGee TD. In vitro attachment of osteoblast-like cells to osteoceramic materials. Dent Mater 1997;13(1):62-8.
    • (1997) Dent. Mater. , vol.13 , Issue.1 , pp. 62-68
    • Keller, J.C.1    Collins, J.G.2    Niederauer, G.G.3    McGee, T.D.4
  • 28
    • 36749093527 scopus 로고    scopus 로고
    • The control of human mesenchymal cell differentiation using nanoscale symmetry and disorder
    • Dalby MJ, Gadegaard N, Tare R, Andar A, Riehle MO, Herzyk P, et al. The control of human mesenchymal cell differentiation using nanoscale symmetry and disorder. Nat Mater 2007;6(12):997-1003.
    • (2007) Nat. Mater. , vol.6 , Issue.12 , pp. 997-1003
    • Dalby, M.J.1    Gadegaard, N.2    Tare, R.3    Andar, A.4    Riehle, M.O.5    Herzyk, P.6
  • 29
    • 47649092532 scopus 로고    scopus 로고
    • Genomic expression of mesenchymal stem cells to altered nanoscale topographies
    • Dalby MJ, Andar A, Nag A, Affrossman S, Tare R, McFarlane S, et al. Genomic expression of mesenchymal stem cells to altered nanoscale topographies. J R Soc Interface 2008;5(26):1055-65.
    • (2008) J. R Soc. Interface , vol.5 , Issue.26 , pp. 1055-1065
    • Dalby, M.J.1    Andar, A.2    Nag, A.3    Affrossman, S.4    Tare, R.5    McFarlane, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.