Akt directly regulates focal adhesion kinase through association and serine phosphorylation: Implication for pressure-induced colon cancer metastasis

American Journal of Physiology - Cell Physiology

Volumn 300, Issue 3, 2011, Pages

  Wang, Shouye ^a,b   Basson, Marc D ^a,b  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Cell adhesion; Cell signaling; Extracellular pressure; Protein kinase B; Serine threonine and tyrosine phosphorylation

Indexed keywords

FOCAL ADHESION KINASE; PROTEIN KINASE B; SERINE; THREONINE;

ARTICLE; AUTOPHOSPHORYLATION; CANCER CELL; CELL ADHESION; COLON CANCER; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME BINDING; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE SEQUENCE; HUMAN; HUMAN TISSUE; METASTASIS; POINT MUTATION; PRESSURE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UPREGULATION;

ADENOCARCINOMA; AMINO ACID SEQUENCE; CACO-2 CELLS; CATALYTIC DOMAIN; COLONIC NEOPLASMS; FOCAL ADHESION PROTEIN-TYROSINE KINASES; GENE SILENCING; HUMANS; NEOPLASM METASTASIS; PHOSPHORYLATION; PRESSURE; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-AKT; SERINE;

EID: 79952182090     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00377.2010     Document Type: Article

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