Enantioselective, biocatalytic reduction of 3-substituted cyclopentenones: Application to the asymmetric synthesis of an hNK-1 receptor antagonist

Organic Letters

Volumn 13, Issue 5, 2011, Pages 1004-1007

  Campos, Kevin R ^a   Klapars, Artis ^a   Kohmura, Yoshinori ^a   Pollard, David ^a   Ishibashi, Hideaki ^a   Kato, Shinji ^a   Takezawa, Akihiro ^a   Waldman, Jacob H ^a   Wallace, Debra J ^a   Chen, Cheng Yi ^a   Yasuda, Nobuyoshi ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPENTANE DERIVATIVE; CYCLOPENTENONE; FUSED HETEROCYCLIC RINGS; NEUROKININ 1 RECEPTOR; PALLADIUM;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; HUMAN; STEREOISOMERISM; SYNTHESIS;

CATALYSIS; CYCLOPENTANES; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; HUMANS; MOLECULAR STRUCTURE; PALLADIUM; RECEPTORS, NEUROKININ-1; STEREOISOMERISM;

EID: 79952169979     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol1030348     Document Type: Article

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