Xenopus laevis as a novel model to study long bone critical-size defect repair by growth factor-mediated regeneration

Tissue Engineering - Part A

Volumn 17, Issue 5-6, 2011, Pages 691-701

  Feng, Liang ^a,b   Milner, Derek J ^b,c   Xia, Chunguang ^a   Nye, Holly L D ^b,c   Redwood, Patrick ^b   Cameron, Jo Ann ^b,c   Stocum, David L ^d   Fang, Nick ^a   Jasiuk, Iwona ^a,b  

^a University of Illinois at Urbana Champaign   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^d Biology SL332   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD VESSELS; CARTILAGE; COMPUTERIZED TOMOGRAPHY; DEFECTS; HYDROGELS; LIGAMENTS; PALLETS; PEPTIDES; PHOTOMASKS; REPAIR; SCAFFOLDS; TISSUE ENGINEERING;

BONE FORMATION; BONE MORPHOGENETIC PROTEINS; BONE REGENERATION; DEFECT REPAIR; ENDOCHONDRAL BONE DEVELOPMENT; FRACTURE REPAIR; GROWTH FACTOR; GROWTH FACTOR DELIVERY; HEXANEDIOL DIACRYLATE; IN-CONTROL; IN-VIVO; LOAD-BEARING; LONG BONE; MICROCOMPUTED TOMOGRAPHY; MODEL SYSTEM; SCAR TISSUES; TIME POINTS; VASCULAR ENDOTHELIAL GROWTH FACTOR; XENOPUS; XENOPUS LAEVIS;

BONE;

ANURA; XENOPUS LAEVIS;

BONE MORPHOGENETIC PROTEIN 4; TISSUE SCAFFOLD; VASCULOTROPIN A;

ANIMAL; ANIMAL MODEL; ARTICLE; BONE; BONE REGENERATION; CHEMISTRY; DRUG EFFECT; HUMAN; IMPLANT; PATHOLOGY; POROSITY; SCANNING ELECTRON MICROSCOPY; WOUND HEALING; XENOPUS LAEVIS;

ANIMALS; BONE AND BONES; BONE MORPHOGENETIC PROTEIN 4; BONE REGENERATION; HUMANS; IMPLANTS, EXPERIMENTAL; MICROSCOPY, ELECTRON, SCANNING; MODELS, ANIMAL; POROSITY; TISSUE SCAFFOLDS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; WOUND HEALING; XENOPUS LAEVIS;

EID: 79952153376     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2010.0123     Document Type: Article

References (61)

1. Hall, B. Repair of Fractures and Regeneration of Growth Plates, in Bones and Cartilage: Development and Evolutionary Skeletal Biology. San Diego: Elsevier Academic Press, 2005, pp. 375-382.
2. Stocum, D. L. Regeneration Biology and Medicine. San Diego: Elsevier Academic Press, 2006.
3. Young, B., et al. Skeletal Tissues, in Wheater's Functional Histology: A Text and Color Atlas. San Diego: Elsevier Limited, 2006, pp. 189-201.
4. Schmitz, J. P., and Hollinger, J. O. The critical size defect as an experimental model for craniomandibulofacial nonunions. Clin Orthop 205, 299, 1986.
5. Pollak, A. N., and Ficke, J. R. Extremity war injuries: challenges in definitive reconstruction. J Am Acad Orthop Surg 16, 628, 2008.
6. Alonso, J., and Regazzoni, P. Bridging bone gaps with the Ilizarov technique. Biologic principles. Clin Plast Surg 18, 497, 1991.
7. Marsh, D. R., et al. The Ilizarov method in nonunion, malunion and infection of fractures. J Bone Joint Surg 79 B, 273, 1997.
8. Kanellopoulos, A. D., and Soucacos, P. N. Management of nonunion with distraction osteogenesis. Injury 37, S51, 2006.
9. Szponder, T., et al. Treatment of long bone fractures in small animals using the Ilizarov method. Med Weter 60, 500, 2004.
10. Rose, R. E. C. The Ilizarov technique in the treatment of tibial bone defects-case reports and review of the literature. West Indian Med J 51, 263, 2002.
11. Maini, L., et al. The Ilizarov method in infected nonunion of fractures. Injury 31, 509, 2000.
12. Knothe Tate, M. L., et al. Testing of a new one-stage bonetransport surgical procedure exploiting the periosteum for the repair of long-bone defects. J Bone Joint Surg Am Vol 89 A, 307, 2007.
13. Gu, Y. D., et al. Long-term results of toe transfer: retrospective analysis. J Reconstr Microsurg 13, 405, 1997.
14. Yoshikawa, T., et al. Bone regeneration by grafting of cultured human bone. Tissue Eng 10, 688, 2004.
15. Mauffrey, C. P. C., Seligson, D., and Krikler, S. How I do it? Bone graft harvest from the proximal laterial tibia. Injury 41, 242, 2010.
16. Younger, E. M., and Chapman, M. W. Morbidity at bone graft donor sites. J Orthop Trauma 3, 192, 1989.
17. Blokhuis, T. J., and Lindner, T. Allograft and bone morphogenetic proteins: an overview. Injury 39 S2, S33, 2008.
18. Oikarinen, J., and Korhonen, L. K. The bone inductive capacity of various bone transplanting materials used for treatment of experimental bone defects. Clin Orthop 140, 208, 1979.
19. Kruyt, M. C., et al. Bone engineering in a critical size defect compared to ectopic implantation in the goat. J Orthop Res 22, 544, 2004.
20. Warnke, P. H., et al. Growth and transplantation of a custom vascularised bone graft in a man. Lancet 364, 766, 2004.
21. Cowan, C. M., et al. Adipose-derived adult stromal cells heal critical-size mouse carvarial defects. Nat Biotechnol 22, 560, 2004.
22. Oest, M. E., et al. Quantitative assessment of scaffold and growth factor-mediated repair of critically sized bone defects. J Orthop Res 25, 941, 2007.
23. Hutmacher, D. W. Scaffolds in tissue engineering bone and cartilage. Biomaterials 21, 2529, 2000.
24. Huang, Y. C., et al. Combined angiogenic and osteogenic factor delivery enhances bone marrow stromal cell-driven bone regeneration. J Bone Mineral Res 20, 848, 2005.
25. Simmons, C. A., et al. Dual growth factor delivery and controlled scaffold degradation enhance in vivo bone formation by transplanted bone marrow stromal cells. Bone 35, 562, 2004.
26. Ripamonti, U., Crooks, J., and Rueger, D. C. Induction of bone formation by recombinant human osteogenic protein-1 and sintered porous hydroxyapatite in adult primates. Plast Reconstr Surg 107, 977, 2001.
27. Ripamonti, U., et al. Induction of endochondral bone formation by recombinant human transforming growth factor-beta 2 in the baboon (Papio ursinus). Growth Factors 17, 269, 2000.
28. Chakkalakal, D. A., et al. Demineralized bone matrix as a biological scaffold for bone repair. Tissue Eng 7, 161, 2001.
29. Gao, T. J., Lindholm, T. S., and Kommonen, B. Composite delivery devices of bone morphogenetic proteins with osteoinduction and osteoconduction in the healing of large bone defect in sheep model. Bone 24, 18, 1999.
30. Hollister, S. J., Maddox, R. D., and Taboas, J. M. Optimal design and fabrication of scaffolds to mimic tissue properties and satisfy biological constraints. Biomaterials 23, 4095, 2002.
31. Cool, S. M., and Nurcombe, V. Substrate induction of osteogenesis from marrow-derived mesenchymal precursors. Stem Cell Dev 14, 632, 2005.
32. Fatkhudinov, T. K., et al. Reparative osteogenesis during transplantation of mesenchymal stem cells. Bull Exp Biol Med 140, 96, 2005.
33. Harris, C. T., and Cooper, L. F. Comparison of bone graft matrices for human mesenchymal stem cell-directed osteogenesis. J Biomed Mater Res 68 A, 747, 2004.
34. Li, W. J., et al. A three-dimensional nanofibrous scaffold for cartilage tissue engineering using human mesenchymal stem cells. Biomaterials 26, 599, 2005.
35. Marcacci, M., et al. Stem cells associated with macroporous bioceramics for long bone repair: 6-to 7-Year outcome of a Pilot Clinical Study. Tissue Eng 13, 947, 2007.
36. Zhu, L., et al. Tissue-engineered bone repair of goat-femur defects with osteogenically induced bone marrow stromal cells. Tissue Eng 12, 423, 2006.
37. Yaszemski, M. J., et al. Evolution of bone transplantation: molecular, cellular and tissue strategies to engineer human bone. Biomaterials 17, 175, 1996.
38. Giardino, R., et al. Bioabsorbable scaffold for in situ bone regeneration. Biomed Pharmacother 60, 386, 2006.
39. Murugan, R., Ramakrishna, S., and Rao, K. P. Nanoporous hydroxy-carbonate apatite scaffold made of natural bone. Mater Lett 60, 2844, 2006.
40. Kim, S. S., et al. Poly (lactide-co-glycolide). Biomaterials 27, 1399, 2006.
41. 3 scaffold for bone tissue engineering. J Biomed Mater Res Part A 76 A, 196, 2006.
42. Zhang, Y., et al. In-situ hardening hydroxyapatite-based scaffold for bone repair. J Mater Sci Mater Med 17, 437, 2006.
43. Navarro, M., et al. Development of a biodegradable composite scaffold for bone tissue engineering: physicochemical, topographical, mechanical, degradation, and biological properties. Adv Polym Sci 200, 209, 2006.
44. Gorna, K., and Gogolewski, S. Biodegradable porous polyurethane scaffolds for tissue repair and regeneration. J Biomed Mater Res Part A 79 A, 128, 2006.
45. Tadic, D., et al. A novel method to produce hydroxyapatite objects with interconnecting porosity that avoids sintering. Biomaterials 25, 3335, 2004.
46. Lin, C. Y., Kikuchi, N., and Hollister, S. J. A novel method for biomaterial scaffold internal architecture design to match bone elastic properties with desired porosity. J Biomech 37, 623, 2004.
47. Boccaccini, A. R., et al. Biodegradable and bioactive polymer. Mater Sci Forum 494, 499, 2005.
48. Thomson, R. C., et al. Hydroxyapatite fiber reinforced poly (alpha-hydroxy ester) foams for bone regeneration. Biomaterials 19, 1935, 1998.
49. Kasten, P., et al. The effect of platelet-rich plasma on healing in critical-size long-bone defects. Biomaterials 29, 3983, 2008.
50. Gerstenfeld, L. C., et al. Fracture healing as a post-natal development process: molecular, spatial and temporal aspects of its regulation. J Cell Biochem 88, 873, 2003.
51. Wei, G., et al. The enhancement of osteogenesis of nanofibrous scaffolds incorporating rhBMP-7 nanospheres. Biomaterials 28, 2087, 2007.
52. Jeon, O., et al. Enchancement of ectopic bone formation by bone morphogenetic protein-2 released from a heparinconjugated poly (L-lactic-co-glycolic acid) scaffold. Biomaterials 28, 2763, 2007.
53. Peng, H., et al. Synergistic enchancement of bone formation and healing by stem cell-expressed VEGF and bone morphogenetic protein 4. J Clin Investig 110, 751, 2002.
54. Nakase, T., et al. Transient and localized expression of bone morphogenic protein 4 messenger RNA during fracture healing. J Bone Mineral Res 9, 651, 1994.
55. Bostrom, M. P., et al. Immunolocalization and expression of bone morphogenetic protein 2 and 4 in fracture healing. J Orthop Res 13, 357, 1995.
56. Gerber, H. P., et al. VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation. Nat Med 5, 623, 1999.
57. Miura, S., Hanaoka, K., and Togashi, S. Skeletogenesis in Xenopus tropicalis: characteristic bone development in an anuran amphibian. Bone 43, 901, 2008.
58. Sun, C. N., et al. Projection micro-stereolithography using digital micro-mirror dynamic mask. Sens Actuators A 121, 113, 2005.
59. Rao, J., et al. Proteomic analysis of blastema formation in regenerating axolotl limbs BioMed Cent Biol 7, 1741, 2009.
60. Burkin, D. J., and Kaufman, S. J. The α7β1 integrin in muscle development and disease. Cell Tissue Res 296, 183, 1999.
61. Milner, D. J., and Kaufman, S. J. α7β1 integrin does not alliviate disease in a mouse model of limb girdle muscular distrophy type 2F. Am J Pathol 170, 609, 2007.