Preventing and managing bronchiolitis obliterans syndrome after allogeneic hematopoietic cell transplantation

Expert Review of Respiratory Medicine

Volumn 5, Issue 1, 2011, Pages 127-135

  Chien, Jason W ^a  

^a Fred Hutchinson Cancer Research Center   (United States)

Author keywords

bronchiolitis obliterans syndrome; graft versus host disease; hematopoietic cell transplantation

Indexed keywords

AZITHROMYCIN; CALCINEURIN INHIBITOR; CASPASE RECRUITMENT DOMAIN PROTEIN 15; CORTICOSTEROID; ETANERCEPT; FLUTICASONE; IMATINIB; MACROLIDE; MONTELUKAST; PREDNISONE;

ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ANTIINFLAMMATORY ACTIVITY; BODY PLETHYSMOGRAPHY; BRONCHIOLITIS OBLITERANS; CHEMOPROPHYLAXIS; CHRONIC GRAFT VERSUS HOST DISEASE; CORTICOSTEROID THERAPY; DIABETES MELLITUS; DRUG DOSE REDUCTION; DRUG MEGADOSE; EARLY DIAGNOSIS; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; GRAFT RECIPIENT; HIGH RESOLUTION COMPUTER TOMOGRAPHY; HUMAN; IMMUNOPATHOGENESIS; IMMUNOSUPPRESSIVE TREATMENT; LUNG FIBROSIS; NONHUMAN; OPPORTUNISTIC INFECTION; OSTEOPOROSIS; OXYGEN THERAPY; PREVALENCE; PULMONARY REHABILITATION; PUVA; RESIDUAL VOLUME; REVIEW; SPIROMETRY; SURVIVOR;

EID: 79952123634     PISSN: 17476348     EISSN: 17476356     Source Type: Journal    
DOI: 10.1586/ers.10.79     Document Type: Review

References (55)

1. Chien JW, Duncan S, Williams KM, Pavletic SZ. Bronchiolitis obliterans syndrome after allogeneic hematopoietic stem cell transplantation - an increasingly recognized manifestation of chronic graft-versus-host disease. Biol. Blood Marrow Transplant. 16(1 Suppl.), S106-S114 (2010).
2. Trulock EP, Christie JD, Edwards LB et al. Registry of the International Society for Heart and Lung Transplantation: twenty-fourth official adult lung and heart-lung transplantation report - 2007. J. (Pubitemid 47199080)
3. Santo Tomas LH, Loberiza FR Jr, Klein JP et al. Risk factors for bronchiolitis obliterans in allogeneic hematopoietic stem-cell transplantation for leukemia. Chest 128(1), 153-161 (2005). (Pubitemid 40994467)
4. Friedrichs B, Tichelli A, Bacigalupo A et al. Long-term outcome and late effects in patients transplanted with mobilised blood or bone marrow: a randomised trial. Lancet Oncol. 11(4), 331-338 (2010).
5. Patriarca F, Skert C, Sperotto A et al. Incidence, outcome, and risk factors of late-onset noninfectious pulmonary complications after unrelated donor stem cell transplantation. Bone Marrow Transplant. 33(7), 751-758 (2004). (Pubitemid 38499931)
6. Sharma S, Nadrous HF, Peters SG et al. Pulmonary complications in adult blood and marrow transplant recipients: autopsy findings. Chest 128(3), 1385-1392 (2005). (Pubitemid 41324422)
7. Marras TK, Chan CK, Lipton JH, Messner HA, Szalai JP, Laupacis A. Long-term pulmonary function abnormalities and survival after allogeneic marrow transplantation. Bone Marrow Transplant. 33(5), 509-517 (2004). (Pubitemid 38425782)
8. Filipovich AH, Weisdorf D, Pavletic S et al. National Institutes of Health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: I. Diagnosis and staging working group report. Biol. Blood Marrow Transplant. 11(12), 945-956 (2005). (Pubitemid 41754712)
9. Au BKC, Au MA, Chien JW. Bronchiolitis obliterans syndrome following allogeneic hematopoietic cell transplantation: prevalence, risk factors, and outcomes according to the National Institutes of Health consensus criteria. Biol. Blood Marrow Transplant. (2011) (In Press).
10. Stein-Streilein J, Lipscomb MF, Hart DA, Darden A. Graft-versus-host reaction in the lung. Transplantation 32(1), 38-44 (1981). (Pubitemid 11069856)
11. Epler GR, Colby TV. The spectrum of bronchiolitis obliterans. Chest 83(2), 161-162 (1983). (Pubitemid 13185676)
12. Clark JG, Schwartz DA, Flournoy N, Sullivan KM, Crawford SW, Thomas ED. Risk factors for airflow obstruction in recipients of bone marrow transplants. Ann. Intern. Med. 107(5), 648-656 (1987). (Pubitemid 18041859)
13. Dudek AZ, Mahaseth H, DeFor TE, Weisdorf DJ. Bronchiolitis obliterans in chronic graft-versus-host disease: analysis of risk factors and treatment outcomes. Biol. Blood Marrow Transplant. 9(10), 657-666 (2003). (Pubitemid 38351785)
14. Chalermskulrat W, Neuringer IP, Brickey WJ et al. Hierarchical contributions of allorecognition pathways in chronic lung rejection. Am. J. Respir. Crit. Care Med. 167(7), 999-1007 (2003). (Pubitemid 36408166)
15. Richards DM, Dalheimer SL, Ehst BD et al. Indirect minor histocompatibility antigen presentation by allograft recipient cells in the draining lymph node leads to the activation and clonal expansion of CD4+ T cells that cause obliterative airways disease. J. Immunol. 172(6), 3469-3479 (2004). (Pubitemid 38337927)
16. Duncan SR, Capetanakis NG, Lawson BR, Theofilopoulos AN. Thymic dendritic cells traffic to thymi of allogeneic recipients and prolong graft survival. J. Clin. Invest. 109(6), 755-764 (2002). (Pubitemid 34263152)
17. Kelly KE, Hertz MI, Mueller DL. T-cell and major histocompatibility complex requirements for obliterative airway disease in heterotopically transplanted murine tracheas. Transplantation 66(6), 764-771 (1998). (Pubitemid 28460111)
18. Neuringer IP, Mannon RB, Coffman TM et al. Immune cells in a mouse airway model of obliterative bronchiolitis. Am. J. Respir. Cell. Mol. Biol. 19(3), 379-386 (1998). (Pubitemid 128354207)
19. Chien JW, Zhao LP, Hansen JA, Fan WH, Parimon T, Clark JG. Genetic variation in bactericidal/permeability-increasing protein influences the risk of developing rapid airflow decline after hematopoietic cell transplantation. Blood 107(5), 2200-2207 (2006). (Pubitemid 43289407)
20. Hildebrandt GC, Granell M, Urbano- Ispizua A et al. Recipient NOD2/CARD15 variants: a novel independent risk factor forthe development of bronchiolitis obliterans after allogeneic stem cell transplantation. Biol. Blood Marrow Transplant. 14(1), 67-74 (2008). (Pubitemid 350286740)
21. Erard V, Chien JW, Kim HW et al. Airflow decline after myeloablative allogeneic hematopoietic cell transplantation: the role of community respiratory viruses. J. Infect. Dis. 193(12), 1619-1625 (2006). (Pubitemid 43839464)
22. Clark JG, Crawford SW, Madtes DK, Sullivan KM. Obstructive lung disease after allogeneic marrow transplantation. Clinical presentation and course. Ann. Intern. Med. 111(5), 368-376 (1989). (Pubitemid 19231290)
23. Curtis DJ, Smale A, Thien F, Schwarer AP, Szer J. Chronic airflow obstruction in long-term survivors of allogeneic bone marrow transplantation. Bone Marrow Transplant. 16(1), 169-173 (1995).
24. Chan CK, Hyland RH, Hutcheon MA et al. Small-airways disease in recipients of allogeneic bone marrow transplants. An analysis of 11 cases and a review of the literature. Medicine (Baltimore) 66(5), 327-340 (1987). (Pubitemid 18020232)
25. Markopoulo KD, Cool CD, Elliot TL et al. Obliterative bronchiolitis: varying presentations and clinicopathological correlation. Eur. Respir. J. 19(1), 20-30 (2002). (Pubitemid 34105563)
26. Philit F, Wiesendanger T, Archimbaud E, Mornex JF, Brune J, Cordier JF. Post-transplant obstructive lung disease (bronchiolitis obliterans): a clinical comparative study of bone marrow and lung transplant patients. Eur. Respir. J. 8(4), 551-558 (1995).
27. Yokoi T, Hirabayashi N, Ito M et al. Broncho-bronchiolitis obliterans as a complication of bone marrow transplantation: a clinicopathological study of eight autopsy cases. Nagoya BMT Group. Virchows Arch. 431(4), 275-282 (1997). (Pubitemid 27470625)
28. Yoshihara S, Yanik G, Cooke KR, Mineishi S. Bronchiolitis obliterans syndrome (BOS), bronchiolitis obliterans organizing pneumonia (BOOP), and other late-onset noninfectious pulmonary complications following allogeneic hematopoietic stem cell transplantation. Biol. Blood Marrow Transplant. 13(7), 749-759 (2007). (Pubitemid 46902446)
29. Williams KM, Chien JW, Gladwin MT, Pavletic SZ. Bronchiolitis obliterans after allogeneic hematopoietic stem cell transplantation. JAMA 302(3), 306-314 (2009).
30. Gunn ML, Godwin JD, Kanne JP, Flowers ME, Chien JW. High-resolution CT findings of bronchiolitis obliterans syndrome after hematopoietic stem cell transplantation. J. Thorac. Imaging 23(4), 244-250 (2008).
31. Ooi GC, Peh WC, Ip M. High-resolution computed tomography of bronchiolitis obliterans syndrome after bone marrow transplantation. Respiration 65(3), 187-191 (1998). (Pubitemid 28302296)
32. Ratjen F, Rjabko O, Kremens B. High-dose corticosteroid therapy for bronchiolitis obliterans after bone marrow transplantation in children. Bone Marrow Transplant. 36(2), 135-138 (2005). (Pubitemid 41030629)
33. Smith EP, Sniecinski I, Dagis AC et al. Extracorporeal photochemotherapy for treatment of drug-resistant graft-vs.-host disease. Biol. Blood Marrow Transplant. 4(1), 27-37 (1998). (Pubitemid 128538798)
34. Besnier DP, Chabannes D, Mahe B et al. Treatment of graft-versus-host disease by extracorporeal photochemotherapy: a pilot study. Transplantation 64(1), 49-54 (1997). (Pubitemid 27327199)
35. Ilhan O, Arat M, Arslan O et al. Extracorporeal photoimmunotherapy for the treatment of steroid refractory progressive chronic graft-versus-host disease. Transfus Apher. Sci. 30(3), 185-187 (2004). (Pubitemid 38698331)
36. Lucid CE, Savani BN, Engelhardt BG et al. Extracorporeal photopheresis in patients with refractory bronchiolitis obliterans developing after allo-SCT. Bone Marrow Transplant. DOI: 10.1038/bmt.2010.152 (2010) (Epub ahead of print).
37. Fullmer JJ, Fan LL, Dishop MK, Rodgers C, Krance R. Successful treatment of bronchiolitis obliterans in a bone marrow transplant patient with tumor necrosis factor-a blockade. Pediatrics 116(3), 767-770 (2005). (Pubitemid 44336698)
38. Majhail NS, Schiffer CA, Weisdorf DJ. Improvement of pulmonary function with imatinib mesylate in bronchiolitis obliterans following allogeneic hematopoietic cell transplantation. Biol. Blood Marrow Transplant. 12(7), 789-791 (2006). (Pubitemid 43899411)
39. Clore JN, Thurby-Hay L. Glucocorticoid-induced hyperglycemia. Endocr. Pract. 15(5), 469-474 (2009).
40. McDonough AK, Curtis JR, Saag KG. The epidemiology of glucocorticoid-associated adverse events. Curr. Opin. Rheumatol. 20(2), 131-137 (2008). (Pubitemid 351339883)
41. Norman BC, Jacobsohn D, Williams KM et al. Fluticasone, azithromycin, and monteleukast (FAM) therapy in reducing corticosteroid exposure in bronchiolitis obliterans syndrome after allogeneic hematopoietic stem cell transplant. Bone Marrow Transplant. (2011) (In Press).
42. Bashoura L, Gupta S, Jain A et al. Inhaled corticosteroids stabilize constrictive bronchiolitis after hematopoietic stem cell transplantation. Bone Marrow Transplant. 41(1), 63-67 (2008).
43. Bergeron A, Belle A, Chevret S et al. Combined inhaled steroids and bronchodilatators in obstructive airway disease after allogeneic stem cell transplantation. Bone Marrow Transplant. 39(9), 547-553 (2007). (Pubitemid 46629590)
44. Khalid M, Al Saghir A, Saleemi S et al. Azithromycin in bronchiolitis obliterans complicating bone marrow transplantation: a preliminary study. Eur. Respir. J. 25(3), 490-493 (2005). (Pubitemid 40340107)
45. Medoff BD, Seung E, Wain JC et al. BLT1-mediated T cell trafficking is critical for rejection and obliterative bronchiolitis after lung transplantation. J. Exp. Med. 202(1), 97-110 (2005). (Pubitemid 41002913)
46. Wilborn J, Bailie M, Coffey M, Burdick M, Strieter R, Peters-Golden M. Constitutive activation of 5-lipoxygenase in the lungs of patients with idiopathic pulmonary fibrosis. J. Clin. Invest. 97(8), 1827-1836 (1996).
47. Or R, Gesundheit B, Resnick I et al. Sparing effect by montelukast treatment for chronic graft versus host disease: a pilot study. Transplantation 83(5), 577-581 (2007). (Pubitemid 46440246)
48. Sano Y, Date H, Nagahiro I, Aoe M, Shimizu N. Living-donor lobar lung transplantation for bronchiolitis obliterans after bone marrow transplantation. Ann. Thorac. Surg. 79(3), 1051-1052 (2005). (Pubitemid 40288786)
49. Okumura H, Ohtake S, Ontachi Y et al. Living-donor lobar lung transplantation for broncho-bronchiolitis obliterans after allogeneic hematopoietic stem cell transplantation: does bronchiolitis obliterans recur in transplanted lungs? Int. J. Hematol. 86(4), 369-373 (2007).
50. Rabitsch W, Deviatko E, Keil F et al. Successful lung transplantation for bronchiolitis obliterans after allogeneic marrow transplantation. Transplantation 71(9), 1341-1343 (2001). (Pubitemid 32507159)
51. Calhoon JH, Levine S, Anzueto A, Bryan CL, Trinkle JK. Lung transplantation in a patient with a prior bone marrow transplant. Chest 102(3), 948 (1992).
52. Christie JD, Edwards LB, Kucheryavaya AY et al. The Registry of the International Society for Heart and Lung Transplantation: twenty-seventh official adult lung and heart-lung transplant report - 2010. J. Heart Lung Transplant. 29(10), 1104-1118 (2010).
53. Couriel D, Carpenter PA, Cutler C et al. Ancillary therapy and supportive care of chronic graft-versus-host disease: national institutes of health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: V. Ancillary Therapy and Supportive Care Working Group Report. Biol. Blood Marrow Transplant. 12(4), 375-396 (2006). (Pubitemid 43380955)
54. Chien JW, Martin PJ, Gooley TA et al. Airflow obstruction after myeloablative allogeneic hematopoietic stem cell transplantation. Am. J. Respir. Crit. Care Med. 168(2), 208-214 (2003). (Pubitemid 36920975)
55. Walter EC, Orozco-Levi M, Ramirez- Sarmiento A et al. Lung function and long-term complications after allogeneic hematopoietic cell transplant. Biol. Blood Marrow Transplant. 16(1), 53-61 (2010).