An RGD-restricted substrate interface is sufficient for the adhesion, growth and cartilage forming capacity of human chondrocytes

European Cells and Materials

Volumn 20, Issue , 2010, Pages 316-328

  Vonwil, Daniel ^a   Schuler, Martin ^b   Barbero, Andrea ^a   Ströbel, Simon ^a   Wendt, David ^a   Textor, Marcus ^c   Aebi, Ueli ^d   Martin, Ivan ^a  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b INSTITUT STRAUMANN AG   (Switzerland)

^c ETH ZURICH   (Switzerland)

^d UNIVERSITY OF BASEL   (Switzerland)

Author keywords

Biomimetics; Cartilage differentiation; Cartilage repair; Cell motility; Cell proliferation

Indexed keywords

ARGINYL-GLYCYL-ASPARTIC ACID; ARGINYLGLYCYLASPARTIC ACID; MACROGOL DERIVATIVE; OLIGOPEPTIDE;

AGED; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CELL ADHESION; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CHEMISTRY; CHONDROGENESIS; CYTOLOGY; HUMAN; METABOLISM; MIDDLE AGED; PHYSIOLOGY; ULTRASTRUCTURE;

AGED; CARTILAGE, ARTICULAR; CELL ADHESION; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CHONDROCYTES; CHONDROGENESIS; HUMANS; MIDDLE AGED; OLIGOPEPTIDES; POLYETHYLENE GLYCOLS;

EID: 79952117210     PISSN: 14732262     EISSN: None     Source Type: Journal    
DOI: 10.22203/eCM.v020a26     Document Type: Article

References (66)

1. Aszodi A., Hunziker EB, Brakebusch C, Fässler R (2003) Beta1 integrins regulate chondrocyte rotation, G1 progression, and cytokinesis. Genes Dev 17: 2465-2479.
2. Aulthouse A., Beck M, Griffey E, Sanford J, Arden K, Machado M., Horton W (1989) Expression of the human chondrocyte phenotype in vitro. In Vitro Cell Dev Biol Plant 25: 659-668.
3. Baneyx G., Baugh L, Vogel V (2002) Fibronectin extension and unfolding within cell matrix fibrils controlled by cytoskeletal tension. Proc Natl Acad Sci USA 99: 5139-5143.
4. Barbero A., Ploegert S, Heberer M, Martin I (2003) Plasticity of clonal populations of dedifferentiated adult human articular chondrocytes. Arthritis Rheum 48: 1315-1325.
5. Barbero A., Grogan SP, Schafer D, Heberer M, Mainil-Varlet P. (2004) Age related changes in human articular chondrocyte yield, proliferation and post-expansion chondrogenic capacity. Osteoarthritis Cartilage 12: 476-484.
6. Barbero A., Grogan SP, Mainil-Varlet P, Martin I (2006) Expansion on specific substrates regulates the phenotype and differentiation capacity of human articular chondrocytes. J Cell Biochem 98: 1140-1149.
7. Benya P. D, Shaffer JD (1982) Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels. Cell 30: 215-224.
8. Brittberg M. (2008) Autologous chondrocyte implantation-Technique and long-term follow-up. Injury 39: 40-49.
9. Brodkin K. R, Garcia AJ, Levenston ME (2004) Chondrocyte phenotypes on different extracellular matrix monolayers. Biomaterials 25: 5929-5938.
10. Connelly J. T, Garcia AJ, Levenston ME (2008) Interactions between integrin ligand density and cytoskeletal integrity regulate BMSC chondrogenesis. J Cell Physiol 217: 145-154.
11. Connelly J. T, Garcia AJ, Levenston ME (2007) Inhibition of in vitro chondrogenesis in RGD-modified three-dimensional alginate gels. Biomaterials 28: 1071-1083.
12. Cui Y. L, Qi AD, Liu WG, Wang XH, Wang H, Ma DM, Yao K. D (2003) Biomimetic surface modification of poly(-lactic acid) with chitosan and its effects on articular chondrocytes in vitro. Biomaterials 24: 3859-3868.
13. Darling E. M, Athanasiou KA (2005) Rapid phenotypic changes in passaged articular chondrocyte subpopulations. J Orthopaed Res 23: 425-432.
14. Engler A. J, Sen S, Sweeney HL, Discher DE (2006) Matrix elasticity directs stem cell lineage specification. Cell 126: 677-689.
15. Farndale R. W, Buttle DJ, Barrett AJ (1986) Improved quantitation and discrimination of sulfated glycosaminoglycans by use of dimethylene blue. Biochim Biophys Acta 883: 173-177.
16. Franks W., Tosatti S, Heer F, Seif P, Textor M, Hierlemann A. (2007) Patterned cell adhesion by selfassembled structures for use with a CMOS cell-based biosensor. Biosens Bioelectron 22: 1426-1433.
17. Garciadiego-Cázares D, Rosales C, Hatoh M, Chimal-Monroy J. (2004) Coordination of chondrocyte differentiation and joint formation by d551 integrin in the developing appendicular skeleton. Development 131: 4735-4742.
18. Grant R. P, Spitzfaden C, Altroff H, Campbell ID, Mardon H. J (1997) Structural requirements for biological activity of the ninth and tenth FIII domains of human fibronectin. J Biol Chem 272: 6159-6166.
19. Grogan S. P, Rieser F., Winkelmann V, Berardi S., Mainil-Varlet P. (2003) Static, closed and scaffold-free bioreactor system that permits chondrogenesis in vitro. Osteoarthritis Cartilage 11: 403-411.
20. Hersel U., Dahmen C, Kessler H (2003) RGD modified polymers: Biomaterials for stimulated cell adhesion and beyond. Biomaterials 24: 4385-4415.
21. Heuberger M., Drobek T, Spencer N.D. (2005) Interaction forces and morphology of a protein-resistant poly(ethylene glycol) layer. Biophys J 88: 495-504.
22. Hollander A. P, Heathfield TF, Webber C, Iwata YBR, Rorabeck A. (1994) Increased damage to type II collagen in osteoarthritic articular cartilage detected by a new immunoassay. J Clin Invest 93: 1722-1732.
23. Horbett T. A (1986) Techniques for protein adsorption studies. In: Techniques of Biocompatibility Testing II (Williams DF, ed). CRC Press, Boca Raton, pp 183-213.
24. Hsu S. H, Chang SH, Yen HJ, Whu SW, Tsai CL, Chen DC (2006) Evaluation of biodegradable polyesters modified by type II collagen and Arg-Gly-Asp as tissue engineering scaffolding materials for cartilage regeneration. Artif Organs 30: 42-55.
25. Hsu S., Whu S, Hsieh S, Tsai C, Chen D, Tan T (2004) Evaluation of chitosan-alginate-hyaluronate complexes modified by an RGD-containing protein as tissueengineering scaffold for cartilage repair. Artif Organs 8: 693-703.
26. Hubbell J. A (1999) Bioactive biomaterials. Curr Opin Biotechnol 10: 123-129.
27. Jakob M., Demarteau O, Schafer D, Hintermann B, Dick W, Heberer M (2001) Specific growth factors during the expansion and redifferentiation of adult human articular chondrocytes enhance chondrogenesis and cartilaginous tissue formation in vitro. J Cell Biochem 81: 368-377.
28. Jeschke B., Meyer Jr, Jonczyk A, Kessler H, Adamietz P, Meenen NM, Kantlehner M, Goepfert C, Nies B (2002) RGD-peptides for tissue engineering of articular cartilage. Biomaterials 23: 3455-3463.
29. Kato R., Kaga C, Kunimatsu M, Kobayashi T, Honda H (2006) Peptide array-based interaction assay of solidbound peptides and anchorage-dependant cells and its effectiveness in cell-adhesive peptide design. J Biosci Bioeng 101: 485-495. Kino-Oka M, Yashiki S, Ota Y, Mushiaki Y, Sugawara
30. Kino-Oka M, Yashiki S, Ota Y, Mushiaki Y, Sugawara K, Yamamoto T, Taya M (2005) Subculture of chondrocytes on a collagen type I-coated substrate with supressed cellular dedifferentiation. Tissue Eng 11: 597-608.
31. Koenig A. L, Gambillara V, Grainger DW (2003) Correlating fibronectin adsorption with endothelieal cell adhesion and signalling on polymer substrates. J Biomed Mater Res 64: 20-37.
32. Kowalczynska H. M, Kolos R, Nowak-Wyrzykowska M, Dobkowski J, Elbaum D, Szczepankiewicz A, Kaminski J. (2009) Atomic force microscopy evidence for conformational changes of fibronectin adsorbed on unmodified and sulfonated polystyrene surfaces. J Biomed Mater Res Part A 91A: 1239-1251.
33. Kramer J., Bohrnsen F, Lindner U, Behrens P, Schlenke P, Rohwedel J (2006) In vivo matrix-guided human mesenchymal stem cells. Cell Mol Life Sci 63: 616-626.
34. Kreiner M., Li Z, Beattie J, Kelly SM, Mardon HJ, van der Walle CF (2008) Self-assembling multimeric integrin alpha 5 beta 1 ligands for cell attachment and spreading. Protein Eng Des Sel 21: 553-560.
35. Maheshwari G., Brown G, Lauffenburger DA, Wells A, Griffith L. G (2000) Cell adhesion and motility depend on nanoscale RGD clustering. J Cell Sci 113: 1677-1686.
36. Majd H., Wipff PJ, Buscemi L, Bueno M, Vonwil D, Quinn T. M, Hinz B (2009) A novel method of dynamic culture surface expansion improves mesenchymal stem cell proliferation and phenotype. Stem Cells 27: 200-209.
37. Maniwa S., Ochi M, Motomura T, Nishikori T, Chen J, Naora H. (2001) Effects of hyaluronic acid and basic fibroblast growth factor on motility of chondrocytes and synovial cells in culture. Acta Orthopaed Scand 72: 299-303.
38. Mardon H. J, Grant KE (1994) The role of the 9th and 10th type-III domains of human fibronectin in celladhesion. FEBS Lett 340: 197-201.
39. Marlovits S., Hombauer M, Truppe M, Vecsei V, Schlegel W. (2004) Changes in the ratio of type-I and type-II collagen expression during monolayer culture of human chondrocytes. J Bone Joint Surg Br 86-B: 286-295.
40. McBeath R, Pirone DM, Nelson CM, Bhadriraju K, Chen C. S (2004) Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment. Dev Cell 6: 483-495.
41. McNickle AG, Provencher MT, Cole BJ (2008) Overview of existing cartilage repair technology. Sports Med Arthrosc. 16: 196-201.
42. Mitchison T. J, Cramer LP (1996) Actin-based cell motility and cell locomotion. Cell 84: 371-379.
43. Mrksich M. (2002) What can surface chemistry do for cell biology? Curr Opin Chem Biol 6: 794-797.
44. Nakanishi K., Sakiyama T, Imamura K (2001) On the adsorption of proteins on solid surfaces, a common but very complicated phenomenon. J Biosci Bioeng 91: 233-244.
45. Ochsenhirt S. E, Kokkoli E, McCarthy JB, Tirrell M (2006) Effect of RGD secondary structure and the synergy site PHSRN on cell adhesion, spreading and specific integrin engagement. Biomaterials 27: 3863-3874.
46. Pasche S., De Paul SM, Voros J, Spencer ND, Textor M (2003) Poly(L-lysine)-graft-poly(ethylene glycol) assembled monolayers on niobium oxide surfaces: A quantitative study of the influence of polymer interfacial architecture on resistance to protein adsorption by ToFSIMS and in situ OWLS. Langmuir 19: 9216-9225.
47. Pasche S., Voros J, Griesser HJ, Spencer ND, Textor M (2005) Effects of ionic strength and surface charge on protein adsorption at PEGylated surfaces. J Phys Chem B 109: 17545-17552.
48. Petrie T. A, Capadona JR, Reyes CD, Garcia AJ (2006) Integrin specificity and enhanced cellular activities associated with surfaces presenting a recombinant fibronectin fragment compared to RGD supports. Biomaterials 27: 5459-5470.
49. Rasband W. S (2009) Image J. U. S. National Institutes of Health, Bethesda, MD, USA.
50. Redick S. D, Settles DL, Briscoe G, Erickson HP (2000) Defining fibronectin's cell adhesion synergy site by sitedirected mutagenesis. J Cell Biol 149: 521-527.
51. Richter W. (2009) Mesenchymal stem cells and cartilage in situ regeneration. J Int Med 266: 390-405.
52. Ruoslahti E. (1996) RGD and other recognition sequences for integrins. Ann Rev Cell Develop Biol 12: 697-715.
53. Schuler M., Owen GR, Hamilton DW, De Wilde M, Textor M., Brunette DM, Tosatti S (2006a) Biomimetic modification of titanium dental implant model surfaces using the RGDSP-peptide sequence: A cell morphology study. Biomaterials 27: 4003-4015.
54. Schuler M., Trentin D, Textor M, Tosatti SGP (2006b) Biomedical interfaces: titanium surface technology for implants and cell carriers. Nanomedicine 1: 449-463.
55. Schuler M., Hamilton DW, Kunzler TP, Sprecher CM, de Wild M, Brunette DM, Textor M, Tosatti SGP (2009a) Comparison of the response of cultured osteoblasts and osteoblasts outgrown from rat calvarial bone chips to nonfouling KRSR and FHRRIKA-peptide modified rough titanium surfaces. J Biomed Mater Res Part B-Appl Biomater 91B: 517-527.
56. Schuler M., Kunzler TP, de Wild M, Sprecher CM, Trentin D., Brunette DM, Textor M, Tosatti SGP (2009b) Fabrication of TiO2-coated epoxy replicas with identical dual-type surface topographies used in cell culture assays. J Biomed Mater Res Part A 88A: 12-22.
57. Scully S. P, Lee JW, Ghert MA, i W (2001) The role of the extracellular matrix in articular chondrocyte regulation. Clin Orthopaed Rel Res 391: S72-S89.
58. Shakibei M., De Souza P, Merker H-J (1997) Integrin expression and collagen type II implicated in maintenance of chondrocyte shape in monolayer culture: An immunomorphological study. Cell Biol Int 21: 115-125.
59. Stockdale F. E, Abbott J, Holtzer S, Holtzer H (1963) The loss of phenotypic traits by differentiated cells: II. Behavior of chondrocytes and their progeny in vitro. Dev Biol 7: 293-302.
60. Talbot J., Tarjus G, Van Tassel PR, Viot P (2000) From car parking to protein adsorption: an overview of sequential adsorption processes. Colloids Surf A: Physicochem Eng Asp 165: 287-324.
61. Tosatti S., Schwartz Z, Campbell C, Cochran DL, VandeVondele S, Hubbell JA, Denzer A, Simpson J, Wieland M., Lohmann CH, Textor M, Boyan BD (2004) RGD-containing peptide GCRGYGRGDSPG reduces enhancement of osteoblast differentiation by poly(Llysine)-graft-poly(ethylene glycol)-coated titanium surfaces. J Biomed Mater Res Part A 68A: 458-472. Van der Kraan PM, Buma P, van Kuppevelt T, van Den
62. Van der Kraan PM, Buma P, van Kuppevelt T, van Den Berg W. B (2002) Interaction of chondrocytes, extracellular matrix and growth factors: relevance for articular cartilage tissue engineering. Osteoarthritis Cartilage 10: 631-637.
63. VandeVondele S, Vöros J, Hubbell JA (2003) RGDgrafted poly-L-lysine-graft-poly(ethylene glycol) copolymers block non-specific protein adsorption while promoting cell adhesion. Biotechnol Bioeng 82: 784-790.
64. Vogel V. (2006) Mechanotransduction involving multimodular proteins: Converting force into biochemical signals. Ann Rev Biophys Biomol Struct 35: 459-488.
65. Woods A., Wang GY, Beier F (2005) RhoA/ROCK signaling regulates Sox9 expression and actin organization during chondrogenesis. J Biol Chem 280: 11626-11634.
66. Yoo J. U, Barthel TS, Nishimura K, Solchaga L, Caplan AI, Goldberg VM, Johnstone B (1998) The chondrogenic potential of human bone-marrow-derived mesenchymal progenitor cells. J Bone Joint Surg-Am 80A: 1745-1757.