-
1
-
-
58549092371
-
Organiztaion and dynamics of PDZ-domain-related supramodules in the postsynaptic density
-
Feng W & Zhang M (2009) Organiztaion and dynamics of PDZ-domain-related supramodules in the postsynaptic density. Nat Rev Neurosci 10, 87-99.
-
(2009)
Nat Rev Neurosci
, vol.10
, pp. 87-99
-
-
Feng, W.1
Zhang, M.2
-
2
-
-
0031457622
-
Signaling through scaffold, anchoring, and adaptor proteins
-
DOI 10.1126/science.278.5346.2075
-
Pawson T & Scott JD (1997) Signaling through scaffold, anchoring, and adaptor proteins. Science 278, 2075-2080. (Pubitemid 28028310)
-
(1997)
Science
, vol.278
, Issue.5346
, pp. 2075-2080
-
-
Pawson, T.1
Scott, J.D.2
-
3
-
-
58149083028
-
Scaffold proteins and immune-cell signalling
-
Shaw AS & Filbert EL (2009) Scaffold proteins and immune-cell signalling. Nat Rev Immunol 9, 47-56.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 47-56
-
-
Shaw, A.S.1
Filbert, E.L.2
-
4
-
-
68549087161
-
Scaffolds: Interaction platforms for cellular signalling circuits
-
Zeke A, Lukacs M, Lim WA & Remenyi A (2009) Scaffolds: interaction platforms for cellular signalling circuits. Trends Cell Biol 19, 364-374.
-
(2009)
Trends Cell Biol
, vol.19
, pp. 364-374
-
-
Zeke, A.1
Lukacs, M.2
Lim, W.A.3
Remenyi, A.4
-
5
-
-
79952111440
-
Scaffolds are 'active' regulators of signaling modules
-
Alexa A, Varga J & Reményi A (2010) Scaffolds are 'active' regulators of signaling modules. FEBS J 277, 4376-4382.
-
(2010)
FEBS J
, vol.277
, pp. 4376-4382
-
-
Alexa, A.1
Varga, J.2
Reményi, A.3
-
7
-
-
79952111834
-
Organizing signal transduction through A-kinase anchoring proteins (AKAPs)
-
Logue JS & Scott JD (2010) Organizing signal transduction through A-kinase anchoring proteins (AKAPs). FEBS J 277, 4370-4375.
-
(2010)
FEBS J
, vol.277
, pp. 4370-4375
-
-
Logue, J.S.1
Scott, J.D.2
-
8
-
-
67650665028
-
High levels of structural disorder in scaffold proteins as exemplified by a novel neuronal protein, CASK-interactive protein 1
-
Balazs A, Csizmok V, Buday L, Rakacs M, Kiss R, Bokor M, Udupa R, Tompa K & Tompa P (2009) High levels of structural disorder in scaffold proteins as exemplified by a novel neuronal protein, CASK-interactive protein 1. FEBS J 276, 3744-3756.
-
(2009)
FEBS J
, vol.276
, pp. 3744-3756
-
-
Balazs, A.1
Csizmok, V.2
Buday, L.3
Rakacs, M.4
Kiss, R.5
Bokor, M.6
Udupa, R.7
Tompa, K.8
Tompa, P.9
-
9
-
-
20444376186
-
The interplay between structure and function in intrinsically unstructured proteins
-
Tompa P (2005) The interplay between structure and function in intrinsically unstructured proteins. FEBS Lett 579, 3346-3354.
-
(2005)
FEBS Lett
, vol.579
, pp. 3346-3354
-
-
Tompa, P.1
-
12
-
-
62149139644
-
Assembly and structure of protein phosphatase 2A
-
Shi Y (2009) Assembly and structure of protein phosphatase 2A. Sci China C Life Sci 52, 135-146.
-
(2009)
Sci China C Life Sci
, vol.52
, pp. 135-146
-
-
Shi, Y.1
-
13
-
-
40849097955
-
Myosin phosphatase target subunit: Many roles in cell function
-
Matsumura F & Hartshorne DJ (2008) Myosin phosphatase target subunit: many roles in cell function. Biochem Biophys Res Commun 369, 149-156.
-
(2008)
Biochem Biophys Res Commun
, vol.369
, pp. 149-156
-
-
Matsumura, F.1
Hartshorne, D.J.2
-
14
-
-
0033007901
-
Membrane-targeting of signalling molecules by SH2/SH3 domain-containing adaptor proteins
-
Buday L (1999) Membrane-targeting of signalling molecules by SH2/SH3 domain-containing adaptor proteins. Biochim Biophys Acta 1422, 187-204.
-
(1999)
Biochim Biophys Acta
, vol.1422
, pp. 187-204
-
-
Buday, L.1
-
15
-
-
0036015163
-
The Nck family of adapter proteins: Regulators of actin cytoskeleton
-
DOI 10.1016/S0898-6568(02)00027-X, PII S089865680200027X
-
Buday L, Wunderlich L & Tamas P (2002) The Nck family of adapter proteins: regulators of actin cytoskeleton. Cell Signal 14, 723-731. (Pubitemid 34597179)
-
(2002)
Cellular Signalling
, vol.14
, Issue.9
, pp. 723-731
-
-
Buday, L.1
Wunderlich, L.2
Tamas, P.3
-
16
-
-
0032968020
-
Requirement of multiple SH3 domains of Nck for ligand binding
-
DOI 10.1016/S0898-6568(98)00054-0, PII S0898656898000540
-
Wunderlich L, Goher A, Farago A, Downward J & Buday L (1999) Requirement of multiple SH3 domains of Nck for ligand binding. Cell Signal 11, 253-262. (Pubitemid 29185127)
-
(1999)
Cellular Signalling
, vol.11
, Issue.4
, pp. 253-262
-
-
Wunderlich, L.1
Goher, A.2
Farago, A.3
Downward, J.4
Buday, L.5
-
17
-
-
70350405643
-
Phosphoinositide 3-kinase-regulated adapters in lymphocyte activation
-
Zhang TT, Li H, Cheung SM, Costantini JL, Hou S, Al-Alwan M & Marshall AJ (2009) Phosphoinositide 3-kinase-regulated adapters in lymphocyte activation. Immunol Rev 232, 255-272.
-
(2009)
Immunol Rev
, vol.232
, pp. 255-272
-
-
Zhang, T.T.1
Li, H.2
Cheung, S.M.3
Costantini, J.L.4
Hou, S.5
Al-Alwan, M.6
Marshall, A.J.7
-
18
-
-
70349176078
-
Procaspase 8 overexpression in non-small-cell lung cancer promotes apoptosis induced by FLIP silencing
-
Wilson TR, Redmond KM, McLaughlin KM, Crawford N, Gately K, O'Byrne K, Le-Clorrenec C, Holohan C, Fennell DA, Johnston PG et al. (2009) Procaspase 8 overexpression in non-small-cell lung cancer promotes apoptosis induced by FLIP silencing. Cell Death Differ 16, 1352-1361.
-
(2009)
Cell Death Differ
, vol.16
, pp. 1352-1361
-
-
Wilson, T.R.1
Redmond, K.M.2
McLaughlin, K.M.3
Crawford, N.4
Gately, K.5
O'Byrne, K.6
Le-Clorrenec, C.7
Holohan, C.8
Fennell, D.A.9
Johnston, P.G.10
-
19
-
-
0141483011
-
Redirecting tyrosine kinase signaling to an apoptotic caspase pathway through chimeric adaptor proteins
-
DOI 10.1073/pnas.1934711100
-
Howard PL, Chia MC, Del Rizzo S, Liu FF & Pawson T (2003) Redirecting tyrosine kinase signaling to an apoptotic caspase pathway through chimeric adaptor proteins. Proc Natl Acad Sci USA 100, 11267-11272. (Pubitemid 37205924)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.20
, pp. 11267-11272
-
-
Howard, P.L.1
Chia, M.C.2
Del, R.S.3
Liu, F.-F.4
Pawson, T.5
-
20
-
-
33847718707
-
Dynamic control of signaling by modular adaptor proteins
-
Pawson T (2007) Dynamic control of signaling by modular adaptor proteins. Curr Opin Cell Biol 19, 112-116.
-
(2007)
Curr Opin Cell Biol
, vol.19
, pp. 112-116
-
-
Pawson, T.1
-
21
-
-
44449108785
-
Regulation of growth factor signaling by FRS2 family docking/scaffold adaptor proteins
-
Gotoh N (2008) Regulation of growth factor signaling by FRS2 family docking/scaffold adaptor proteins. Cancer Sci 99, 1319-1325.
-
(2008)
Cancer Sci
, vol.99
, pp. 1319-1325
-
-
Gotoh, N.1
-
22
-
-
33746363486
-
Domains, motifs, and scaffolds: The role of modular interactions in the evolution and wiring of cell signaling circuits
-
DOI 10.1146/annurev.biochem.75.103004.142710
-
Bhattacharyya RP, Remenyi A, Yeh BJ & Lim WA (2006) Domains, motifs, and scaffolds: the role of modular interactions in the evolution and wiring of cell signaling circuits. Annu Rev Biochem 75, 655-680. (Pubitemid 44118047)
-
(2006)
Annual Review of Biochemistry
, vol.75
, pp. 655-680
-
-
Bhattacharyya, R.P.1
Remenyi, A.2
Yeh, B.J.3
Lim, W.A.4
-
23
-
-
51249099359
-
Reconstitution and analysis of the multienzyme Escherichia coli RNA degradosome
-
Worrall JA, Gorna M, Crump NT, Phillips LG, Tuck AC, Price AJ, Bavro VN & Luisi BF (2008) Reconstitution and analysis of the multienzyme Escherichia coli RNA degradosome. J Mol Biol 382, 870-883.
-
(2008)
J Mol Biol
, vol.382
, pp. 870-883
-
-
Worrall, J.A.1
Gorna, M.2
Crump, N.T.3
Phillips, L.G.4
Tuck, A.C.5
Price, A.J.6
Bavro, V.N.7
Luisi, B.F.8
-
24
-
-
0030907935
-
NIK is a new Ste20-related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domain
-
DOI 10.1093/emboj/16.6.1279
-
Su YC, Han J, Xu S, Cobb M & Skolnik EY (1997) NIK is a new Ste20-related kinase that binds NCK and MEKK1 and activates the SAPK?JNK cascade via a conserved regulatory domain. EMBO J 16, 1279-1290. (Pubitemid 27136094)
-
(1997)
EMBO Journal
, vol.16
, Issue.6
, pp. 1279-1290
-
-
Su, Y.-C.1
Han, J.2
Xu, S.3
Cobb, M.4
Skolnik, E.Y.5
-
25
-
-
33644848599
-
ILK, PINCH and parvin: The tIPP of integrin signalling
-
Legate KR, Montanez E, Kudlacek O & Fassler R (2006) ILK, PINCH and parvin: the tIPP of integrin signalling. Nat Rev Mol Cell Biol 7, 20-31.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 20-31
-
-
Legate, K.R.1
Montanez, E.2
Kudlacek, O.3
Fassler, R.4
-
26
-
-
0037123605
-
Emerging roles of ubiquitin in transcription regulation
-
DOI 10.1126/science.1067466
-
Conaway RC, Brower CS & Conaway JW (2002) Emerging roles of ubiquitin in transcription regulation. Science 296, 1254-1258. (Pubitemid 34522769)
-
(2002)
Science
, vol.296
, Issue.5571
, pp. 1254-1258
-
-
Conaway, R.C.1
Brower, C.S.2
Conaway, J.W.3
-
28
-
-
0036846371
-
Stress-induced decrease in TRAF2 stability is mediated by Siah2
-
DOI 10.1093/emboj/cdf576
-
Habelhah H, Frew IJ, Laine A, Janes PW, Relaix F, Sassoon D, Bowtell DD & Ronai Z (2002) Stress-induced decrease in TRAF2 stability is mediated by Siah2. EMBO J 21, 5756-5765. (Pubitemid 35315273)
-
(2002)
EMBO Journal
, vol.21
, Issue.21
, pp. 5756-5765
-
-
Habelhah, H.1
Frew, I.J.2
Laine, A.3
Janes, P.W.4
Relaix, F.5
Sassoon, D.6
Bowtell, D.D.L.7
Ronai, Z.8
-
29
-
-
9644252804
-
Characterization of segments from the central region of BRCA1: An intrinsically disordered scaffold for multiple protein-protein and protein-DNA interactions?
-
Mark WY, Liao JC, Lu Y, Ayed A, Laister R, Szymczyna B, Chakrabartty A & Arrowsmith CH (2005) Characterization of segments from the central region of BRCA1: an intrinsically disordered scaffold for multiple protein-protein and protein-DNA interactions? J Mol Biol 345, 275-287.
-
(2005)
J Mol Biol
, vol.345
, pp. 275-287
-
-
Mark, W.Y.1
Liao, J.C.2
Lu, Y.3
Ayed, A.4
Laister, R.5
Szymczyna, B.6
Chakrabartty, A.7
Arrowsmith, C.H.8
-
30
-
-
77950863406
-
Molecular mechanism of multivesicular body biogenesis by ESCRT complexes
-
Wollert T & Hurley JH (2010) Molecular mechanism of multivesicular body biogenesis by ESCRT complexes. Nature 464, 864-869.
-
(2010)
Nature
, vol.464
, pp. 864-869
-
-
Wollert, T.1
Hurley, J.H.2
-
31
-
-
34247899121
-
Functional amyloid - From bacteria to humans
-
DOI 10.1016/j.tibs.2007.03.003, PII S096800040700059X
-
Fowler DM, Koulov AV, Balch WE & Kelly JW (2007) Functional amyloid - from bacteria to humans. Trends Biochem Sci 32, 217-224. (Pubitemid 46694328)
-
(2007)
Trends in Biochemical Sciences
, vol.32
, Issue.5
, pp. 217-224
-
-
Fowler, D.M.1
Koulov, A.V.2
Balch, W.E.3
Kelly, J.W.4
-
32
-
-
0037188377
-
Intrinsic disorder and protein function
-
DOI 10.1021/bi012159+
-
Dunker AK, Brown CJ, Lawson JD, Iakoucheva LM & Obradovic Z (2002) Intrinsic disorder and protein function. Biochemistry 41, 6573-6582. (Pubitemid 34547347)
-
(2002)
Biochemistry
, vol.41
, Issue.21
, pp. 6573-6582
-
-
Dunker, A.K.1
Brown, C.J.2
Lawson, J.D.3
Iakoucheva, L.M.4
Obradovic, Z.5
-
33
-
-
14644435825
-
Intrinsically unstructured proteins and their functions
-
DOI 10.1038/nrm1589
-
Dyson HJ & Wright PE (2005) Intrinsically unstructured proteins and their functions. Nat Rev Mol Cell Biol 6, 197-208. (Pubitemid 40314921)
-
(2005)
Nature Reviews Molecular Cell Biology
, vol.6
, Issue.3
, pp. 197-208
-
-
Dyson, H.J.1
Wright, P.E.2
-
34
-
-
0036803243
-
Intrinsically unstructured proteins
-
Tompa P (2002) Intrinsically unstructured proteins. Trends Biochem Sci 27, 527-533.
-
(2002)
Trends Biochem Sci
, vol.27
, pp. 527-533
-
-
Tompa, P.1
-
35
-
-
2142757231
-
Preformed structural elements feature in partner recognition by intrinsically unstructured proteins
-
DOI 10.1016/j.jmb.2004.03.017, PII S0022283604003079
-
Fuxreiter M, Simon I, Friedrich P & Tompa P (2004) Preformed structural elements feature in partner recognition by intrinsically unstructured proteins. J Mol Biol 338, 1015-1026. (Pubitemid 38542830)
-
(2004)
Journal of Molecular Biology
, vol.338
, Issue.5
, pp. 1015-1026
-
-
Fuxreiter, M.1
Simon, I.2
Friedrich, P.3
Tompa, P.4
-
36
-
-
34249695447
-
Local structural disorder imparts plasticity on linear motifs
-
DOI 10.1093/bioinformatics/btm035
-
Fuxreiter M, Tompa P & Simon I (2007) Local structural disorder imparts plasticity on linear motifs. Bioinformatics 23, 950-956. (Pubitemid 47050581)
-
(2007)
Bioinformatics
, vol.23
, Issue.8
, pp. 950-956
-
-
Fuxreiter, M.1
Tompa, P.2
Simon, I.3
-
37
-
-
65249102824
-
Close encounters of the third kind: Disordered domains and the interactions of proteins
-
Tompa P, Fuxreiter M, Oldfield CJ, Simon I, Dunker AK & Uversky VN (2009) Close encounters of the third kind: disordered domains and the interactions of proteins. Bioessays 31, 328-335.
-
(2009)
Bioessays
, vol.31
, pp. 328-335
-
-
Tompa, P.1
Fuxreiter, M.2
Oldfield, C.J.3
Simon, I.4
Dunker, A.K.5
Uversky, V.N.6
-
38
-
-
3042848952
-
Evidence for dynamically organized modularity in the yeast protein-protein interaction network
-
DOI 10.1038/nature02555
-
Han JD, Bertin N, Hao T, Goldberg DS, Berriz GF, Zhang LV, Dupuy D, Walhout AJ, Cusick ME, Roth FP et al. (2004) Evidence for dynamically organized modularity in the yeast protein-protein interaction network. Nature 430, 88-93. (Pubitemid 38915230)
-
(2004)
Nature
, vol.430
, Issue.6995
, pp. 88-93
-
-
Han, J.-D.J.1
Berlin, N.2
Hao, T.3
Goldberg, D.S.4
Berriz, G.F.5
Zhang, L.V.6
Dupuy, D.7
Walhout, A.J.M.8
Cusick, M.E.9
Roth, F.P.10
Vidal, M.11
-
39
-
-
33750999318
-
Disorder and sequence repeats in hub proteins and their implications for network evolution
-
DOI 10.1021/pr060171o
-
Dosztanyi Z, Chen J, Dunker AK, Simon I & Tompa P (2006) Disorder and sequence repeats in hub proteins and their implications for network evolution. J Proteome Res 5, 2985-2995. (Pubitemid 44749217)
-
(2006)
Journal of Proteome Research
, vol.5
, Issue.11
, pp. 2985-2995
-
-
Dosztanyi, Z.1
Chen, J.2
Dunker, A.K.3
Simon, I.4
Tompa, P.5
-
41
-
-
38149063767
-
Structural disorder promotes assembly of protein complexes
-
Hegyi H, Schad E & Tompa P (2007) Structural disorder promotes assembly of protein complexes. BMC Struct Biol 7, 65.
-
(2007)
BMC Struct Biol
, vol.7
, pp. 65
-
-
Hegyi, H.1
Schad, E.2
Tompa, P.3
-
42
-
-
24044538903
-
IUPred: Web server for the prediction of intrinsically unstructured regions of proteins based on estimated energy content
-
DOI 10.1093/bioinformatics/bti541
-
Dosztanyi Z, Csizmok V, Tompa P & Simon I (2005) IUPred: web server for the prediction of intrinsically unstructured regions of proteins based on estimated energy content. Bioinformatics 21, 3433-3434. (Pubitemid 41222453)
-
(2005)
Bioinformatics
, vol.21
, Issue.16
, pp. 3433-3434
-
-
Dosztanyi, Z.1
Csizmok, V.2
Tompa, P.3
Simon, I.4
|