Dose dependent in vivo metabolic characteristics of titanium dioxide nanoparticles

Journal of Nanoscience and Nanotechnology

Volumn 10, Issue 12, 2010, Pages 8575-8583

  Tang, Meng ^a   Zhang, Ting ^a   Xue, Yuying ^a   Wang, Shu ^a   Huang, Mingming ^b   Yang, Yang ^a   Lu, Minyu ^a   Lei, Hao ^b   Kong, Lu ^a   Yuepu, Pu ^a  

^a SOUTHEAST UNIVERSITY   (China)

^b Wuhan National Laboratory for Optoelectronics   (China)

Author keywords

Metabonomics; Nanoparticle; Nanotoxicity; TiO 2

Indexed keywords

2-OXOGLUTARATE; BIOCHEMICAL ASSAY; DIMETHYLAMINES; DOSE-DEPENDENT; HIGH DOSE; IN-VIVO; INTRATRACHEAL INSTILLATION; KEY COMPONENT; LOW DOSE; LUNG TISSUE; METABOLIC CHARACTERISTICS; METABOLIC FUNCTION; METABONOMICS; NANO-TIO; NANOTOXICITY; NANOTOXICOLOGY; RAT URINE; TIO; TITANIUM DIOXIDE NANOPARTICLES;

AMINO ACIDS; BODY FLUIDS; LIVER; METABOLISM; METABOLITES; NANOPARTICLES; TISSUE; TITANIUM; TITANIUM DIOXIDE;

AGGLOMERATION;

METAL NANOPARTICLE; TITANIUM; TITANIUM DIOXIDE;

ANIMAL; ARTICLE; CHEMICALLY INDUCED DISORDER; CHEMISTRY; CYTOCHEMISTRY; DOSE RESPONSE; INHALATIONAL DRUG ADMINISTRATION; MALE; METABOLISM; METABOLOMICS; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE; PARTICLE SIZE; PNEUMONIA; PRINCIPAL COMPONENT ANALYSIS; RAT; SERUM; SPRAGUE DAWLEY RAT; URINE;

ADMINISTRATION, INHALATION; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; HISTOCYTOCHEMISTRY; MALE; METABOLOMICS; METAL NANOPARTICLES; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PARTICLE SIZE; PNEUMONIA; PRINCIPAL COMPONENT ANALYSIS; RATS; RATS, SPRAGUE-DAWLEY; SERUM; TITANIUM; URINE;

EID: 79952114292     PISSN: 15334880     EISSN: None     Source Type: Journal    
DOI: 10.1166/jnn.2010.2482     Document Type: Conference Paper

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