Neutrophilic differentiation modulates the apoptotic response of HL-60 cells to sodium butyrate and sodium valproate

Neoplasma

Volumn 57, Issue 5, 2010, Pages 438-448

  Vrba, J ^a   Dolezel, P ^a   Ulrichova, J ^a  

^a PALACKÝ UNIVERSITY   (Czech Republic)

Author keywords

All trans retinoic acid; Apoptosis; Butyrate; Cell cycle; Differentiation; Valproate

Indexed keywords

BUTYRIC ACID; CASPASE 3; CASPASE 9; DIMETHYL SULFOXIDE; PROTEIN P67; PROTEIN P67PHOX; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; RETINOIC ACID; UNCLASSIFIED DRUG; VALINOMYCIN; VALPROIC ACID; BUTYRIC ACID DERIVATIVE; HISTONE DEACETYLASE INHIBITOR;

APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL DIFFERENTIATION; CELL MEMBRANE; CELL NUCLEUS; CELL STRAIN HL 60; CONTROLLED STUDY; DNA FRAGMENTATION; DOSE RESPONSE; DRUG CYTOTOXICITY; DRUG POTENTIATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MEMBRANE DAMAGE; MITOCHONDRIAL MEMBRANE POTENTIAL; NEUTROPHIL; NEUTROPHILIC DIFFERENTIATION; PROTEIN EXPRESSION; CELL CYCLE; CYTOLOGY; DRUG EFFECT; METABOLISM;

APOPTOSIS; BUTYRATES; CASPASE 3; CASPASE 9; CELL CYCLE; CELL DIFFERENTIATION; DIMETHYL SULFOXIDE; HISTONE DEACETYLASE INHIBITORS; HL-60 CELLS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; NEUTROPHILS; TRETINOIN; VALPROIC ACID;

EID: 79952114141     PISSN: 00282685     EISSN: None     Source Type: Journal    
DOI: 10.4149/neo_2010_05_438     Document Type: Article

References (44)

1. MARKS PA, XU WS. Histone deacetylase inhibitors: Potential in cancer therapy. J Cell Biochem 2009; 107: 600-608. doi:10.1002/jcb.22185
2. BOYD AW, METCALF D. Induction of differentiation in HL60 leukaemic cells: a cell cycle dependent all-or-none event. Leuk Res 1984; 8: 27-43. doi:10.1016/0145-2126(84)90029-8
3. CHENG YC, LIN H, HUANG MJ, CHOW JM, LIN S et al. Downregulation of c-Myc is critical for valproic acidinduced growth arrest and myeloid differentiation of acute myeloid leukemia. Leuk Res 2007; 31: 1403-1411. doi:10.1016/ j.leukres.2007.03.012
4. GURVICH N, TSYGANKOVA OM, MEINKOTH JL, KLEIN PS. Histone deacetylase is a target of valproic acid-mediated cellular differentiation. Cancer Res 2004; 64: 1079-1086. doi:10.1158/0008-5472.CAN-03-0799
5. AMIN HM, SAEED S, ALKAN S. Histone deacetylase inhibitors induce caspase-dependent apoptosis and downregulation of daxx in acute promyelocytic leukaemia with t(15;17). Br J Haematol 2001; 115: 287-297. doi:10.1046/j.1365-2141.2001.03123.x
6. REZACOVA M, VAVROVA J, VOKURKOVA D, ZASKODOVA D. Effect of valproic acid and antiapoptotic cytokines on differentiation and apoptosis induction of human leukemia cells. Gen Physiol Biophys 2006; 25: 65-79.
7. ZIMRA Y, WASSERMAN L, MARON L, SHAKLAI M, NUDELMAN A et al. Butyric acid and pivaloyloxymethyl butyrate, AN-9, a novel butyric acid derivative, induce apoptosis in HL-60 cells. J Cancer Res Clin Oncol 1997; 123: 152-160.
8. MINUCCI S, NERVI C, LO COCO F, PELICCI PG. Histone deacetylases: a common molecular target for differentiation treatment of acute myeloid leukemias? Oncogene 2001; 20: 3110-3115. doi:10.1038/sj.onc.1204336
9. OZPOLAT B. Acute promyelocytic leukemia and differentiation therapy: molecular mechanisms of differentiation, retinoic acid resistance and novel treatments. Turk J Hematol 2009; 26: 47-61.
10. GRIGNANI F, DE MATTEIS S, NERVI C, TOMASSONI L, GELMETTI V et al. Fusion proteins of the retinoic acid receptor-α recruit histone deacetylase in promyelocytic leukaemia. Nature 1998; 391: 815-818. doi:10.1038/35901
11. MARTIN SJ, BRADLEY JG, COTTER TG. HL-60 cells induced to differentiate towards neutrophils subsequently die via apoptosis. Clin Exp Immunol 1990; 79: 448-453. 534969
12. OTAKE Y, SENGUPTA TK, BANDYOPADHYAY S, SPICER EK, FERNANDES DJ. Retinoid-induced apoptosis in HL-60 cells is associated with nucleolin down-regulation and destabilization of Bcl-2 mRNA. Mol Pharmacol 2005; 67: 319-326. doi:10.1124/mol.104.006080
13. OZEKI M, SHIVELY JE. Differential cell fates induced by all-trans retinoic acid-treated HL-60 human leukemia cells. J Leukoc Biol 2008; 84: 769-779. doi:10.1189/jlb.1207817
14. WATSON RW, ROTSTEIN OD, PARODO J, BITAR R, HACKAM D et al. Granulocytic differentiation of HL-60 cells results in spontaneous apoptosis mediated by increased caspase expression. FEBS Lett 1997; 412: 603-609. doi:10.1016/S0014-5793(97)00779-5
15. KETLEY NJ, ALLEN PD, KELSEY SM, NEWLAND AC. Modulation of idarubicin-induced apoptosis in human acute myeloid leukemia blasts by all-trans retinoic acid, 1,25(OH)2 vitamin D3, and granulocyte-macrophage colony-stimulating factor. Blood 1997; 90: 4578-4587.
16. KETLEY NJ, ALLEN PD, KELSEY SM, NEWLAND AC. Mechanisms of resistance to apoptosis in human AML blasts: the role of differentiation-induced perturbations of cell-cycle checkpoints. Leukemia 2000; 14: 620-628. doi:10.1038/sj.leu.2401715
17. KIKUCHI H, IIZUKA R, SUGIYAMA S, GON G, MORI H et al. Monocytic differentiation modulates apoptotic response to cytotoxic anti-Fas antibody and tumor necrosis factor α in human monoblast U937 cells. J Leukoc Biol 1996; 60: 778-783.
18. VONDRACEK J, SHEARD MA, KREJCI P, MINKSOVA K, HOFMANOVA J et al. Modulation of death receptor-mediated apoptosis in differentiating human myeloid leukemia HL-60 cells. J Leukoc Biol 2001; 69: 794-802.
19. DEL BINO G, LI X, TRAGANOS F, DARZYNKIEWICZ Z. Altered susceptibility of differentiating HL-60 cells to apoptosis induced by antitumor drugs. Leukemia 1994; 8: 281-288.
20. SHIIKI K, YOSHIKAWA H, KINOSHITA H, TAKEDA M, UENO A et al. Potential mechanisms of resistance to TRAIL/ Apo2L-induced apoptosis in human promyelocytic leukemia HL-60 cells during granulocytic differentiation. Cell Death Differ 2000; 7: 939-946. doi:10.1038/sj.cdd.4400727
21. WANG X, STUDZINSKI GP. Antiapoptotic action of 1,25-dihydroxyvitamin D3 is associated with increased mitochondrial MCL-1 and RAF-1 proteins and reduced release of cytochrome c. Exp Cell Res 1997; 235: 210-217. doi:10.1006/ excr.1997.3667
22. JASEK E, MIRECKA J, LITWIN JA. Effect of differentiating agents (all-trans retinoic acid and phorbol 12-myristate 13-acetate) on drug sensitivity of HL60 and NB4 cells in vitro. Folia Histochem Cytobiol 2008; 46: 323-330. doi:10.2478/ v10042-008-0080-x
23. SOLARY E, BERTRAND R, KOHN KW, POMMIER Y. Differential induction of apoptosis in undifferentiated and differentiated HL-60 cells by DNA topoisomerase I and II inhibitors. Blood 1993; 81: 1359-1368.
24. SORDET O, BETTAIEB A, BRUEY JM, EYMIN B, DROIN N et al. Selective inhibition of apoptosis by TPA-induced differentiation of U937 leukemic cells. Cell Death Differ 1999; 6: 351-361. doi:10.1038/sj.cdd.4400499
25. SORDET O, REBE C, LEROY I, BRUEY JM, GARRIDO C et al. Mitochondria-targeting drugs arsenic trioxide and lonidamine bypass the resistance of TPA-differentiated leukemic cells to apoptosis. Blood 2001; 97: 3931-3940. doi:10.1182/blood. V97.12.3931
26. VRBA J, DOLEZEL P, VICAR J, ULRICHOVA J. Cytotoxic activity of sanguinarine and dihydrosanguinarine in human promyelocytic leukemia HL-60 cells. Toxicol In Vitro 2009; 23: 580-588. doi:10.1016/j.tiv.2009.01.016
27. COLLINS SJ. The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression. Blood 1987; 70: 1233-1244.
28. MURPHY BM, O'NEILL AJ, ADRAIN C, WATSON RW, MARTIN SJ. The apoptosome pathway to caspase activation in primary human neutrophils exhibits dramatically reduced requirements for cytochrome c. J Exp Med 2003; 197: 625-632. doi:10.1084/jem.20021862
29. VAN RAAM BJ, SLUITER W, DE WIT E, ROOS D, VERHOEVEN AJ et al. Mitochondrial membrane potential in human neutrophils is maintained by complex III activity in the absence of supercomplex organisation. PLoS One 2008; 3: e2013. doi:10.1371/journal.pone.0002013
30. MARTIN SJ, REUTELINGSPERGER CP, MCGAHON AJ, RADER JA, VAN SCHIE RC et al. Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl. J Exp Med 1995; 182: 1545-1556. doi:10.1084/jem.182.5.1545
31. INAI Y, YABUKI M, KANNO T, AKIYAMA J, YASUDA T et al. Valinomycin induces apoptosis of ascites hepatoma cells (AH-130) in relation to mitochondrial membrane potential. Cell Struct Funct 1997; 22: 555-563. doi:10.1247/csf.22.555
32. FREW AJ, JOHNSTONE RW, BOLDEN JE. Enhancing the apoptotic and therapeutic effects of HDAC inhibitors. Cancer Lett 2009; 280: 125-133. doi:10.1016/j.canlet.2009.02.042
33. KAWAGOE R, KAWAGOE H, SANO K. Valproic acid induces apoptosis in human leukemia cells by stimulating both caspase-dependent and-independent apoptotic signaling pathways. Leuk Res 2002; 26: 495-502. doi:10.1016/S0145-2126(01)00151-5
34. JING Y, XIA L, WAXMAN S. Targeted removal of PML-RARα protein is required prior to inhibition of histone deacetylase for overcoming all-trans retinoic acid differentiation resistance in acute promyelocytic leukemia. Blood 2002; 100: 1008-1013. doi:10.1182/blood.V100.3.1008
35. ROSATO RR, ALMENARA JA, DAI Y, GRANT S. Simultaneous activation of the intrinsic and extrinsic pathways by histone deacetylase (HDAC) inhibitors and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) synergistically induces mitochondrial damage and apoptosis in human leukemia cells. Mol Cancer Ther 2003; 2: 1273-1284.
36. TSIFTSOGLOU AS, PAPPAS IS, VIZIRIANAKIS IS. Mechanisms involved in the induced differentiation of leukemia cells. Pharmacol Ther 2003; 100: 257-290. doi:10.1016/ j.pharmthera.2003.09.002
37. COLLINS SJ, ROBERTSON KA, MUELLER L. Retinoic acidinduced granulocytic differentiation of HL-60 myeloid leukemia cells is mediated directly through the retinoic acid receptor (RAR-α). Mol Cell Biol 1990; 10: 2154-2163. 60563
38. COLLINS JM, FOSTER KA. Differentiation of promyelocytic (HL-60) cells into mature granulocytes: mitochondrial-specific rhodamine 123 fluorescence. J Cell Biol 1983; 96: 94-99. doi:10.1083/jcb.96.1.94
39. SANTOS-BENEIT AM, MOLLINEDO F. Expression of genes involved in initiation, regulation, and execution of apoptosis in human neutrophils and during neutrophil differentiation of HL-60 cells. J Leukoc Biol 2000; 67: 712-724.
40. NAUMOVSKI L, CLEARY ML. Bcl2 inhibits apoptosis associated with terminal differentiation of HL-60 myeloid leukemia cells. Blood 1994; 83: 2261-2267.
41. GOTTLIEB E, ARMOUR SM, HARRIS MH, THOMPSON CB. Mitochondrial membrane potential regulates matrix configuration and cytochrome c release during apoptosis. Cell Death Differ 2003; 10: 709-717. doi:10.1038/sj.cdd.4401231
42. MAIANSKI NA, GEISSLER J, SRINIVASULA SM, ALNEMRI ES, ROOS D et al. Functional characterization of mitochondria in neutrophils: a role restricted to apoptosis. Cell Death Differ 2004; 11: 143-153. doi:10.1038/sj.cdd.4401320
43. ROBERTSON JD, ORRENIUS S, ZHIVOTOVSKY B. Review: nuclear events in apoptosis. J Struct Biol 2000; 129: 346-358. doi:10.1006/jsbi.2000.4254
44. SEALY L, CHALKLEY R. DNA associated with hyperacetylated histone is preferentially digested by DNase I. Nucleic Acids Res 1978; 5: 1863-1876. doi:10.1093/nar/5.6.1863