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Volumn 1, Issue 1, 2009, Pages 89-96

A systems biology approach to defining metastatic biomarkers and signaling pathways

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Indexed keywords

TUMOR MARKER;

EID: 79952113836     PISSN: 19395094     EISSN: 1939005X     Source Type: Journal    
DOI: 10.1002/wsbm.6     Document Type: Article
Times cited : (8)

References (83)
  • 1
    • 33746851956 scopus 로고    scopus 로고
    • Tumor metastasis: mechanistic insights and clinical challenges
    • Steeg PS. Tumor metastasis: mechanistic insights and clinical challenges. Nat Med 2006, 12(8):895-904.
    • (2006) Nat Med , vol.12 , Issue.8 , pp. 895-904
    • Steeg, P.S.1
  • 2
    • 18244409687 scopus 로고    scopus 로고
    • Gene expression profiling predicts clinical outcome of breast cancer
    • van 't Veer LJ, et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature 2002, 415(6871):530-536.
    • (2002) Nature , vol.415 , Issue.6871 , pp. 530-536
    • van 't Veer, L.J.1
  • 3
    • 0037226593 scopus 로고    scopus 로고
    • A molecular signature of metastasis in primary solid tumors
    • Ramaswamy S, et al. A molecular signature of metastasis in primary solid tumors. Nat Genet 2003, 33(1):49-54.
    • (2003) Nat Genet , vol.33 , Issue.1 , pp. 49-54
    • Ramaswamy, S.1
  • 4
    • 0037158692 scopus 로고    scopus 로고
    • A progression puzzle
    • Bernards R, Weinberg RA. A progression puzzle. Nature 2002, 418(6900):823.
    • (2002) Nature , vol.418 , Issue.6900 , pp. 823
    • Bernards, R.1    Weinberg, R.A.2
  • 5
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990, 61(5):759-767.
    • (1990) Cell , vol.61 , Issue.5 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 6
    • 34247269026 scopus 로고    scopus 로고
    • Genetic determinants of cancer metastasis
    • Nguyen DX, Massague J. Genetic determinants of cancer metastasis. Nat Rev Genet 2007, 8(5):341-352.
    • (2007) Nat Rev Genet , vol.8 , Issue.5 , pp. 341-352
    • Nguyen, D.X.1    Massague, J.2
  • 7
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000, 100(1):57-70.
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 8
    • 0037137519 scopus 로고    scopus 로고
    • A gene-expression signature as a predictor of survival in breast cancer
    • van de Vijver MJ, et al. A gene-expression signature as a predictor of survival in breast cancer. N Engl J Med 2002, 347(25):1999-2009.
    • (2002) N Engl J Med , vol.347 , Issue.25 , pp. 1999-2009
    • van de Vijver, M.J.1
  • 9
    • 0346734120 scopus 로고    scopus 로고
    • Gene expression profiles of primary breast tumors maintained in distant metastases
    • Weigelt B, et al. Gene expression profiles of primary breast tumors maintained in distant metastases. Proc Natl Acad Sci U S A 2003, 100(26):15901-15905.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.26 , pp. 15901-15905
    • Weigelt, B.1
  • 10
    • 0031823908 scopus 로고    scopus 로고
    • Identification of inbred mouse strains harboring genetic modifiers of mammary tumor age of onset and metastatic progression
    • Lifsted T, et al. Identification of inbred mouse strains harboring genetic modifiers of mammary tumor age of onset and metastatic progression. Int J Cancer 1998, 77(4):640-644.
    • (1998) Int J Cancer , vol.77 , Issue.4 , pp. 640-644
    • Lifsted, T.1
  • 11
    • 0035893391 scopus 로고    scopus 로고
    • Predisposition to efficient mammary tumor metastatic progression is linked to the breast cancer metastasis suppressor gene Brms1
    • Hunter KW, et al. Predisposition to efficient mammary tumor metastatic progression is linked to the breast cancer metastasis suppressor gene Brms1. Cancer Res 2001, 61(24):8866-8872.
    • (2001) Cancer Res , vol.61 , Issue.24 , pp. 8866-8872
    • Hunter, K.W.1
  • 12
    • 25844511053 scopus 로고    scopus 로고
    • Sipa1 is a candidate for underlying the metastasis efficiency modifier locus Mtes1
    • Park YG, et al. Sipa1 is a candidate for underlying the metastasis efficiency modifier locus Mtes1. Nat Genet 2005, 37(10):1055-1062.
    • (2005) Nat Genet , vol.37 , Issue.10 , pp. 1055-1062
    • Park, Y.G.1
  • 13
    • 33746506286 scopus 로고    scopus 로고
    • Germline polymorphisms in SIPA1 are associated with metastasis and other indicators of poor prognosis in breast cancer
    • Crawford NP, et al. Germline polymorphisms in SIPA1 are associated with metastasis and other indicators of poor prognosis in breast cancer. Breast Cancer Res 2006, 8(2):R16.
    • (2006) Breast Cancer Res , vol.8 , Issue.2
    • Crawford, N.P.1
  • 14
    • 44849094464 scopus 로고    scopus 로고
    • Survival in breast cancer is familial
    • Hemminki K, et al. Survival in breast cancer is familial. Breast Cancer Res Treat 2008, 110(1):177-182.
    • (2008) Breast Cancer Res Treat , vol.110 , Issue.1 , pp. 177-182
    • Hemminki, K.1
  • 15
    • 43249111294 scopus 로고    scopus 로고
    • Concordance of survival in family members with prostate cancer
    • Hemminki K, et al. Concordance of survival in family members with prostate cancer. J Clin Oncol 2008, 26(10):1705-1709.
    • (2008) J Clin Oncol , vol.26 , Issue.10 , pp. 1705-1709
    • Hemminki, K.1
  • 16
    • 35448951201 scopus 로고    scopus 로고
    • Familial concordance in cancer survival: a Swedish population-based study
    • Lindstrom LS, et al. Familial concordance in cancer survival: a Swedish population-based study. Lancet Oncol 2007, 8(11):1001-1006.
    • (2007) Lancet Oncol , vol.8 , Issue.11 , pp. 1001-1006
    • Lindstrom, L.S.1
  • 17
    • 44049103194 scopus 로고    scopus 로고
    • Survival in bladder and renal cell cancers is familial
    • Ji J, et al. Survival in bladder and renal cell cancers is familial. J Am Soc Nephrol 2008, 19(5):985-991.
    • (2008) J Am Soc Nephrol , vol.19 , Issue.5 , pp. 985-991
    • Ji, J.1
  • 18
    • 23144461051 scopus 로고    scopus 로고
    • Genes that mediate breast cancer metastasis to lung
    • Minn AJ, et al. Genes that mediate breast cancer metastasis to lung. Nature 2005, 436(7050):518-524.
    • (2005) Nature , vol.436 , Issue.7050 , pp. 518-524
    • Minn, A.J.1
  • 19
    • 0038488950 scopus 로고    scopus 로고
    • A multigenic program mediating breast cancer metastasis to bone
    • Kang Y, et al. A multigenic program mediating breast cancer metastasis to bone. Cancer Cell 2003, 3(6):537-549.
    • (2003) Cancer Cell , vol.3 , Issue.6 , pp. 537-549
    • Kang, Y.1
  • 20
    • 20144386127 scopus 로고    scopus 로고
    • Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival
    • Chang HY, et al. Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival. Proc Natl Acad Sci USA 2005, 102(10):3738-3743.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.10 , pp. 3738-3743
    • Chang, H.Y.1
  • 21
    • 33644551073 scopus 로고    scopus 로고
    • Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers
    • Chi JT, et al. Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers. PLoS Med 2006, 3(3):e47.
    • (2006) PLoS Med , vol.3 , Issue.3
    • Chi, J.T.1
  • 22
    • 22744445394 scopus 로고    scopus 로고
    • Determination of stromal signatures in breast carcinoma
    • West RB, et al. Determination of stromal signatures in breast carcinoma. PLoS Biol 2005, 3(6):e187.
    • (2005) PLoS Biol , vol.3 , Issue.6
    • West, R.B.1
  • 23
    • 38849160275 scopus 로고    scopus 로고
    • Characterization of heterotypic interaction effects in vitro to deconvolute global gene expression profiles in cancer
    • Buess M, et al. Characterization of heterotypic interaction effects in vitro to deconvolute global gene expression profiles in cancer. Genome Biol 2007, 8(9):R191.
    • (2007) Genome Biol , vol.8 , Issue.9
    • Buess, M.1
  • 24
    • 20444460289 scopus 로고    scopus 로고
    • MicroRNA expression profiles classify human cancers
    • Lu J, et al. MicroRNA expression profiles classify human cancers. Nature 2005, 435(7043):834-838.
    • (2005) Nature , vol.435 , Issue.7043 , pp. 834-838
    • Lu, J.1
  • 25
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: genomics, biogenesis, mechanism, and function
    • Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116(2):281-297.
    • (2004) Cell , vol.116 , Issue.2 , pp. 281-297
    • Bartel, D.P.1
  • 26
    • 4143142117 scopus 로고    scopus 로고
    • MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias
    • Calin GA, et al. MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias. Proc Natl Acad Sci U S A 2004, 101(32):11755-11760.
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.32 , pp. 11755-11760
    • Calin, G.A.1
  • 27
    • 23844555119 scopus 로고    scopus 로고
    • MicroRNA gene expression deregulation in human breast cancer
    • Iorio MV, et al. MicroRNA gene expression deregulation in human breast cancer. Cancer Res 2005, 65(16):7065-7070.
    • (2005) Cancer Res , vol.65 , Issue.16 , pp. 7065-7070
    • Iorio, M.V.1
  • 28
    • 37349096992 scopus 로고    scopus 로고
    • MicroRNA signature predicts survival and relapse in lung cancer
    • Yu SL, et al. MicroRNA signature predicts survival and relapse in lung cancer. Cancer Cell 2008, 13(1):48-57.
    • (2008) Cancer Cell , vol.13 , Issue.1 , pp. 48-57
    • Yu, S.L.1
  • 29
    • 33644819964 scopus 로고    scopus 로고
    • Unique microRNA molecular profiles in lung cancer diagnosis and prognosis
    • Yanaihara N, et al. Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. Cancer Cell 2006, 9(3):189-198.
    • (2006) Cancer Cell , vol.9 , Issue.3 , pp. 189-198
    • Yanaihara, N.1
  • 30
    • 0142120587 scopus 로고    scopus 로고
    • Reduced accumulation of specific microRNAs in colorectal neoplasia
    • Michael MZ, et al. Reduced accumulation of specific microRNAs in colorectal neoplasia. Mol Cancer Res 2003, 1(12):882-891.
    • (2003) Mol Cancer Res , vol.1 , Issue.12 , pp. 882-891
    • Michael, M.Z.1
  • 31
    • 3042752769 scopus 로고    scopus 로고
    • An oligonucleotide microchip for genome-wide microRNA profiling in human and mouse tissues
    • Liu CG, et al. An oligonucleotide microchip for genome-wide microRNA profiling in human and mouse tissues. Proc Natl Acad Sci USA 2004, 101(26):9740-9744.
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.26 , pp. 9740-9744
    • Liu, C.G.1
  • 32
    • 48949119481 scopus 로고    scopus 로고
    • Breast cancer metastasis: a microRNA story
    • Negrini M, Calin GA. Breast cancer metastasis: a microRNA story. Breast Cancer Res 2008, 10(2):203.
    • (2008) Breast Cancer Res , vol.10 , Issue.2 , pp. 203
    • Negrini, M.1    Calin, G.A.2
  • 33
    • 47249091921 scopus 로고    scopus 로고
    • The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2
    • Korpal M, et al. The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2. J Biol Chem 2008, 283(22):14910-14914.
    • (2008) J Biol Chem , vol.283 , Issue.22 , pp. 14910-14914
    • Korpal, M.1
  • 34
    • 38049115129 scopus 로고    scopus 로고
    • Endogenous human microRNAs that suppress breast cancer metastasis
    • Tavazoie SF, et al. Endogenous human microRNAs that suppress breast cancer metastasis. Nature 2008, 451(7175):147-152.
    • (2008) Nature , vol.451 , Issue.7175 , pp. 147-152
    • Tavazoie, S.F.1
  • 35
    • 40249092910 scopus 로고    scopus 로고
    • MicroRNA-21 targets tumor suppressor genes in invasion and metastasis
    • Zhu S, et al. MicroRNA-21 targets tumor suppressor genes in invasion and metastasis. Cell Res 2008, 18(3):350-359.
    • (2008) Cell Res , vol.18 , Issue.3 , pp. 350-359
    • Zhu, S.1
  • 36
    • 35148886434 scopus 로고    scopus 로고
    • Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
    • Ma L, Teruya-Feldstein J, Weinberg RA. Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 2007, 449(7163):682-688.
    • (2007) Nature , vol.449 , Issue.7163 , pp. 682-688
    • Ma, L.1    Teruya-Feldstein, J.2    Weinberg, R.A.3
  • 37
    • 38849107424 scopus 로고    scopus 로고
    • The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis
    • Huang Q, et al. The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis. Nat Cell Biol 2008, 10(2):202-210.
    • (2008) Nat Cell Biol , vol.10 , Issue.2 , pp. 202-210
    • Huang, Q.1
  • 38
    • 33745168962 scopus 로고    scopus 로고
    • microRNAs exhibit high frequency genomic alterations in human cancer
    • Zhang L, et al. microRNAs exhibit high frequency genomic alterations in human cancer. Proc Natl Acad Sci USA 2006, 103(24):9136-9141.
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.24 , pp. 9136-9141
    • Zhang, L.1
  • 39
    • 18744396337 scopus 로고    scopus 로고
    • Frequent deletions and downregulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
    • Calin GA, et al. Frequent deletions and downregulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci USA 2002, 99(24):15524-15529.
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.24 , pp. 15524-15529
    • Calin, G.A.1
  • 40
    • 13844250828 scopus 로고    scopus 로고
    • Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors
    • Pollack JR, et al. Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors. Proc Natl Acad Sci USA 2002, 99(20):12963-12968.
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.20 , pp. 12963-12968
    • Pollack, J.R.1
  • 41
    • 33745288277 scopus 로고    scopus 로고
    • Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene
    • Kim M, et al. Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene. Cell 2006, 125(7):1269-1281.
    • (2006) Cell , vol.125 , Issue.7 , pp. 1269-1281
    • Kim, M.1
  • 42
    • 42549112561 scopus 로고    scopus 로고
    • Array-based Comparative Genomic Hybridization (aCGH) analysis is a useful tool for distinguishing primary pulmonary from metastatic neuroendocrine carcinoma to the lung
    • Mhawech-Fauceglia P, et al. Array-based Comparative Genomic Hybridization (aCGH) analysis is a useful tool for distinguishing primary pulmonary from metastatic neuroendocrine carcinoma to the lung. Appl Immunohistochem Mol Morphol 2008, 16(3):291-295.
    • (2008) Appl Immunohistochem Mol Morphol , vol.16 , Issue.3 , pp. 291-295
    • Mhawech-Fauceglia, P.1
  • 43
    • 33947529520 scopus 로고    scopus 로고
    • Using array-comparative genomic hybridization to define molecular portraits of primary breast cancers
    • Chin SF, et al. Using array-comparative genomic hybridization to define molecular portraits of primary breast cancers. Oncogene 2007, 26(13):1959-1970.
    • (2007) Oncogene , vol.26 , Issue.13 , pp. 1959-1970
    • Chin, S.F.1
  • 44
    • 33845191779 scopus 로고    scopus 로고
    • Genomic and transcriptional aberrations linked to breast cancer pathophysiologies
    • Chin K, et al. Genomic and transcriptional aberrations linked to breast cancer pathophysiologies. Cancer Cell 2006, 10(6):529-541.
    • (2006) Cancer Cell , vol.10 , Issue.6 , pp. 529-541
    • Chin, K.1
  • 45
    • 39749108733 scopus 로고    scopus 로고
    • High-resolution aCGH and expression profiling identifies a novel genomic subtype of ER negative breast cancer
    • Chin SF, et al. High-resolution aCGH and expression profiling identifies a novel genomic subtype of ER negative breast cancer. Genome Biol 2007, 8(10):R215.
    • (2007) Genome Biol , vol.8 , Issue.10
    • Chin, S.F.1
  • 46
    • 3242672465 scopus 로고    scopus 로고
    • Whole genome scanning identifies genotypes associated with recurrence and metastasis in prostate tumors
    • Paris PL, et al. Whole genome scanning identifies genotypes associated with recurrence and metastasis in prostate tumors. Hum Mol Genet 2004, 13(13):1303-1313.
    • (2004) Hum Mol Genet , vol.13 , Issue.13 , pp. 1303-1313
    • Paris, P.L.1
  • 47
    • 33846320072 scopus 로고    scopus 로고
    • Clonal and parallel evolution of primary lung cancers and their metastases revealed by molecular dissection of cancer cells
    • Takahashi K, et al. Clonal and parallel evolution of primary lung cancers and their metastases revealed by molecular dissection of cancer cells. Clin Cancer Res 2007, 13(1):111-120.
    • (2007) Clin Cancer Res , vol.13 , Issue.1 , pp. 111-120
    • Takahashi, K.1
  • 48
    • 33846626476 scopus 로고    scopus 로고
    • Heterogeneity of mammary lesions represent molecular differences
    • Namba R, et al. Heterogeneity of mammary lesions represent molecular differences. BMC Cancer 2006, 6:275.
    • (2006) BMC Cancer , vol.6 , pp. 275
    • Namba, R.1
  • 49
    • 42449119330 scopus 로고    scopus 로고
    • High-resolution array comparative genomic hybridization of single micrometastatic tumor cells
    • Fuhrmann C, et al. High-resolution array comparative genomic hybridization of single micrometastatic tumor cells. Nucleic Acids Res 2008, 36(7):e39.
    • (2008) Nucleic Acids Res , vol.36 , Issue.7
    • Fuhrmann, C.1
  • 50
    • 0041302570 scopus 로고    scopus 로고
    • Evidence emerges for early metastasis and parallel evolution of primary and metastatic tumors
    • Gray JW. Evidence emerges for early metastasis and parallel evolution of primary and metastatic tumors. Cancer Cell 2003, 4(1):4-6.
    • (2003) Cancer Cell , vol.4 , Issue.1 , pp. 4-6
    • Gray, J.W.1
  • 51
    • 33845931347 scopus 로고    scopus 로고
    • Identification of alterations in DNA copy number in host stromal cells during tumor progression
    • Pelham RJ, et al. Identification of alterations in DNA copy number in host stromal cells during tumor progression. Proc Natl Acad Sci USA 2006, 103(52):19848-19853.
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.52 , pp. 19848-19853
    • Pelham, R.J.1
  • 52
    • 42549152045 scopus 로고    scopus 로고
    • No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas
    • Qiu W, et al. No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas. Nat Genet 2008, 40(5):650-655.
    • (2008) Nat Genet , vol.40 , Issue.5 , pp. 650-655
    • Qiu, W.1
  • 53
    • 3142512612 scopus 로고    scopus 로고
    • Molecular characterization of the tumor microenvironment in breast cancer
    • Allinen M, et al. Molecular characterization of the tumor microenvironment in breast cancer. Cancer Cell 2004, 6(1):17-32.
    • (2004) Cancer Cell , vol.6 , Issue.1 , pp. 17-32
    • Allinen, M.1
  • 54
    • 10744226105 scopus 로고    scopus 로고
    • Genetic alterations in the peritumoral stromal cells of malignant and borderline epithelial ovarian tumors as indicated by allelic imbalance on chromosome 3p
    • Tuhkanen H, et al. Genetic alterations in the peritumoral stromal cells of malignant and borderline epithelial ovarian tumors as indicated by allelic imbalance on chromosome 3p. Int J Cancer 2004, 109(2):247-252.
    • (2004) Int J Cancer , vol.109 , Issue.2 , pp. 247-252
    • Tuhkanen, H.1
  • 55
    • 33646885230 scopus 로고    scopus 로고
    • Total-genome analysis of BRCA1/2-related invasive carcinomas of the breast identifies tumor stroma as potential landscaper for neoplastic initiation
    • Weber F, et al. Total-genome analysis of BRCA1/2-related invasive carcinomas of the breast identifies tumor stroma as potential landscaper for neoplastic initiation. Am J Hum Genet 2006, 78(6):961-972.
    • (2006) Am J Hum Genet , vol.78 , Issue.6 , pp. 961-972
    • Weber, F.1
  • 56
    • 0033016717 scopus 로고    scopus 로고
    • Correlation between protein and mRNA abundance in yeast
    • Gygi SP, et al. Correlation between protein and mRNA abundance in yeast. Mol Cell Biol 1999, 19(3):1720-1730.
    • (1999) Mol Cell Biol , vol.19 , Issue.3 , pp. 1720-1730
    • Gygi, S.P.1
  • 57
    • 2942585115 scopus 로고    scopus 로고
    • Proteomic phenotyping: metastatic and invasive breast cancer
    • Hathout Y, et al. Proteomic phenotyping: metastatic and invasive breast cancer. Cancer Lett 2004, 210(2):245-253.
    • (2004) Cancer Lett , vol.210 , Issue.2 , pp. 245-253
    • Hathout, Y.1
  • 58
    • 35648989121 scopus 로고    scopus 로고
    • Proteomics-based strategy to delineate the molecular mechanisms of the metastasis suppressor gene BRMS1
    • Rivera J, Megias D, Bravo J. Proteomics-based strategy to delineate the molecular mechanisms of the metastasis suppressor gene BRMS1. J Proteome Res 2007, 6(10):4006-4018.
    • (2007) J Proteome Res , vol.6 , Issue.10 , pp. 4006-4018
    • Rivera, J.1    Megias, D.2    Bravo, J.3
  • 59
    • 38849124320 scopus 로고    scopus 로고
    • Alterations in Gemin5 expression contribute to alternative mRNA splicing patterns and tumor cell motility
    • Lee JH, et al. Alterations in Gemin5 expression contribute to alternative mRNA splicing patterns and tumor cell motility. Cancer Res 2008, 68(3):639-644.
    • (2008) Cancer Res , vol.68 , Issue.3 , pp. 639-644
    • Lee, J.H.1
  • 60
    • 33750143779 scopus 로고    scopus 로고
    • Quantitative proteomic and genomic profiling reveals metastasis-related protein expression patterns in gastric cancer cells
    • Chen YR, et al. Quantitative proteomic and genomic profiling reveals metastasis-related protein expression patterns in gastric cancer cells. J Proteome Res 2006, 5(10):2727-2742.
    • (2006) J Proteome Res , vol.5 , Issue.10 , pp. 2727-2742
    • Chen, Y.R.1
  • 61
    • 33745823914 scopus 로고    scopus 로고
    • Parallel analysis of transcript and translation profiles: identification of metastasis-related signal pathways differentially regulated by drug and genetic modifications
    • Yang H, et al. Parallel analysis of transcript and translation profiles: identification of metastasis-related signal pathways differentially regulated by drug and genetic modifications. J Proteome Res 2006, 5(7):1555-1567.
    • (2006) J Proteome Res , vol.5 , Issue.7 , pp. 1555-1567
    • Yang, H.1
  • 62
    • 0031822837 scopus 로고    scopus 로고
    • Tissue microarrays for highthroughput molecular profiling of tumor specimens
    • Kononen J, et al. Tissue microarrays for highthroughput molecular profiling of tumor specimens. Nat Med 1998, 4(7):844-847.
    • (1998) Nat Med , vol.4 , Issue.7 , pp. 844-847
    • Kononen, J.1
  • 63
    • 0035061867 scopus 로고    scopus 로고
    • Tissue microarray technology for high-throughput molecular profiling of cancer
    • Kallioniemi OP, et al. Tissue microarray technology for high-throughput molecular profiling of cancer. Hum Mol Genet 2001, 10(7):657-662.
    • (2001) Hum Mol Genet , vol.10 , Issue.7 , pp. 657-662
    • Kallioniemi, O.P.1
  • 64
    • 0036852721 scopus 로고    scopus 로고
    • Automated subcellular localization and quantification of protein expression in tissue microarrays
    • Camp RL, Chung GG, Rimm DL. Automated subcellular localization and quantification of protein expression in tissue microarrays. Nat Med 2002, 8(11):1323-1327.
    • (2002) Nat Med , vol.8 , Issue.11 , pp. 1323-1327
    • Camp, R.L.1    Chung, G.G.2    Rimm, D.L.3
  • 65
    • 9244241036 scopus 로고    scopus 로고
    • Automated quantitative analysis of HDM2 expression in malignant melanoma shows association with early-stage disease and improved outcome
    • Berger AJ, et al. Automated quantitative analysis of HDM2 expression in malignant melanoma shows association with early-stage disease and improved outcome. Cancer Res 2004, 64(23):8767-8772.
    • (2004) Cancer Res , vol.64 , Issue.23 , pp. 8767-8772
    • Berger, A.J.1
  • 66
    • 1242338881 scopus 로고    scopus 로고
    • Quantitative determination of expression of the prostate cancer protein alpha-methylacyl-CoA racemase using automated quantitative analysis (AQUA): a novel paradigm for automated and continuous biomarker measurements
    • Rubin MA, et al. Quantitative determination of expression of the prostate cancer protein alpha-methylacyl-CoA racemase using automated quantitative analysis (AQUA): a novel paradigm for automated and continuous biomarker measurements. Am J Pathol 2004, 164(3):831-840.
    • (2004) Am J Pathol , vol.164 , Issue.3 , pp. 831-840
    • Rubin, M.A.1
  • 67
    • 21344437943 scopus 로고    scopus 로고
    • Using a xenograft model of human breast cancer metastasis to find genes associated with clinically aggressive disease
    • Kluger HM, et al. Using a xenograft model of human breast cancer metastasis to find genes associated with clinically aggressive disease. Cancer Res 2005, 65(13):5578-5587.
    • (2005) Cancer Res , vol.65 , Issue.13 , pp. 5578-5587
    • Kluger, H.M.1
  • 68
    • 27644506613 scopus 로고    scopus 로고
    • Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression
    • Varambally S, et al. Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression. Cancer Cell 2005, 8(5):393-406.
    • (2005) Cancer Cell , vol.8 , Issue.5 , pp. 393-406
    • Varambally, S.1
  • 69
    • 33846109371 scopus 로고    scopus 로고
    • Direct cancer tissue proteomics: a method to identify candidate cancer biomarkers from formalin-fixed paraffin-embedded archival tissues
    • Hwang SI, et al. Direct cancer tissue proteomics: a method to identify candidate cancer biomarkers from formalin-fixed paraffin-embedded archival tissues. Oncogene 2007, 26(1):65-76.
    • (2007) Oncogene , vol.26 , Issue.1 , pp. 65-76
    • Hwang, S.I.1
  • 70
    • 32044450268 scopus 로고    scopus 로고
    • Transcending the biomarker mindset: deciphering disease mechanisms at the single cell level
    • Danna EA, Nolan GP. Transcending the biomarker mindset: deciphering disease mechanisms at the single cell level. Curr Opin Chem Biol 2006, 10(1):20-27.
    • (2006) Curr Opin Chem Biol , vol.10 , Issue.1 , pp. 20-27
    • Danna, E.A.1    Nolan, G.P.2
  • 71
    • 0033593013 scopus 로고    scopus 로고
    • Activity-based protein profiling: the serine hydrolases
    • Liu Y, Patricelli MP, Cravatt BF. Activity-based protein profiling: the serine hydrolases. Proc Natl Acad Sci USA 1999, 96(26):14694-14699.
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.26 , pp. 14694-14699
    • Liu, Y.1    Patricelli, M.P.2    Cravatt, B.F.3
  • 72
    • 0031470482 scopus 로고    scopus 로고
    • Proteases and protease inhibitors in tumor progression
    • DeClerck YA, et al. Proteases and protease inhibitors in tumor progression. Adv Exp Med Biol 1997, 425:89-97.
    • (1997) Adv Exp Med Biol , vol.425 , pp. 89-97
    • DeClerck, Y.A.1
  • 73
    • 0028598887 scopus 로고
    • Protease inhibitors: role and potential therapeutic use in human cancer
    • DeClerck YA, Imren S. Protease inhibitors: role and potential therapeutic use in human cancer.Eur J Cancer 1994, 30A(14):2170-2180.
    • (1994) Eur J Cancer , vol.30 A , Issue.14 , pp. 2170-2180
    • DeClerck, Y.A.1    Imren, S.2
  • 74
    • 4644279779 scopus 로고    scopus 로고
    • Carcinoma and stromal enzyme activity profiles associated with breast tumor growth in vivo
    • Jessani N, et al. Carcinoma and stromal enzyme activity profiles associated with breast tumor growth in vivo. Proc Natl Acad Sci USA 2004, 101(38):13756-13761.
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.38 , pp. 13756-13761
    • Jessani, N.1
  • 75
    • 33748526171 scopus 로고    scopus 로고
    • New perspectives on hereditary influences in metastatic progression
    • Crawford NP, Hunter KW. New perspectives on hereditary influences in metastatic progression. Trends Genet 2006, 22(10):555-561.
    • (2006) Trends Genet , vol.22 , Issue.10 , pp. 555-561
    • Crawford, N.P.1    Hunter, K.W.2
  • 76
    • 0038481970 scopus 로고    scopus 로고
    • The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited
    • Fidler IJ. The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nat Rev Cancer 2003, 3(6):453-458.
    • (2003) Nat Rev Cancer , vol.3 , Issue.6 , pp. 453-458
    • Fidler, I.J.1
  • 77
    • 5044228029 scopus 로고    scopus 로고
    • Genetic predisposition to cancer-insights from population genetics
    • Frank SA. Genetic predisposition to cancer-insights from population genetics. Nat Rev Genet 2004, 5(10):764-772.
    • (2004) Nat Rev Genet , vol.5 , Issue.10 , pp. 764-772
    • Frank, S.A.1
  • 78
    • 0642335059 scopus 로고    scopus 로고
    • Allelic diversity in the host genetic background may be an important determinant in tumor metastatic dissemination
    • Hunter KW. Allelic diversity in the host genetic background may be an important determinant in tumor metastatic dissemination. Cancer Lett 2003, 200(2):97-105.
    • (2003) Cancer Lett , vol.200 , Issue.2 , pp. 97-105
    • Hunter, K.W.1
  • 79
    • 1642391048 scopus 로고    scopus 로고
    • Host genetics and tumour metastasis
    • Hunter KW. Host genetics and tumour metastasis. Br J Cancer 2004, 90(4):752-755.
    • (2004) Br J Cancer , vol.90 , Issue.4 , pp. 752-755
    • Hunter, K.W.1
  • 80
    • 0037994177 scopus 로고    scopus 로고
    • Genetic background is an important determinant of metastatic potential
    • Hunter K, Welch DR, Liu ET. Genetic background is an important determinant of metastatic potential. Nat Genet 2003, 34(1):23-24.
    • (2003) Nat Genet , vol.34 , Issue.1 , pp. 23-24
    • Hunter, K.1    Welch, D.R.2    Liu, E.T.3
  • 81
    • 33644833555 scopus 로고    scopus 로고
    • Mapping normal and cancer cell signalling networks: towards single-cell proteomics
    • Irish JM, Kotecha N, Nolan GP. Mapping normal and cancer cell signalling networks: towards single-cell proteomics. Nat Rev Cancer 2006, 6(2):146-155.
    • (2006) Nat Rev Cancer , vol.6 , Issue.2 , pp. 146-155
    • Irish, J.M.1    Kotecha, N.2    Nolan, G.P.3
  • 82
    • 18844419736 scopus 로고    scopus 로고
    • Functional genomic analysis of cancer metastasis: biologic insights and clinical implications
    • Kang Y. Functional genomic analysis of cancer metastasis: biologic insights and clinical implications. Expert Rev Mol Diagn 2005, 5(3):385-395.
    • (2005) Expert Rev Mol Diagn , vol.5 , Issue.3 , pp. 385-395
    • Kang, Y.1
  • 83
    • 33747030845 scopus 로고    scopus 로고
    • Protein biomarker discovery and validation: the long and uncertain path to clinical utility
    • Rifai N, Gillette MA, Carr SA. Protein biomarker discovery and validation: the long and uncertain path to clinical utility. Nat Biotechnol 2006, 24(8):971-983
    • (2006) Nat Biotechnol , vol.24 , Issue.8 , pp. 971-983
    • Rifai, N.1    Gillette, M.A.2    Carr, S.A.3


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