-
1
-
-
0035921849
-
Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line
-
Strohmaier H, Spruck CH, Kaiser P, Won KA, Sangfelt O, Reed SI. Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line. Nature 2001; 413: 316-22.
-
(2001)
Nature
, vol.413
, pp. 316-22
-
-
Strohmaier, H.1
Spruck, C.H.2
Kaiser, P.3
Won, K.A.4
Sangfelt, O.5
Reed, S.I.6
-
2
-
-
33750590972
-
Genetic and expression aberrations of E3 ubiquitin ligases in human breast cancer
-
Chen C, Seth AK, Aplin AE. Genetic and expression aberrations of E3 ubiquitin ligases in human breast cancer. Mol Cancer Res 2006; 4: 695-707.
-
(2006)
Mol Cancer Res
, vol.4
, pp. 695-707
-
-
Chen, C.1
Seth, A.K.2
Aplin, A.E.3
-
3
-
-
38549086019
-
FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation
-
Welcker M, Clurman BE. FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation. Nat Rev Cancer 2008; 8: 83-93.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 83-93
-
-
Welcker, M.1
Clurman, B.E.2
-
4
-
-
0034538306
-
C-myc amplification in breast cancer: a meta-analysis of its occurrence and prognostic relevance
-
Deming SL, Nass SJ, Dickson RB, Trock BJ. C-myc amplification in breast cancer: a meta-analysis of its occurrence and prognostic relevance. Br J Cancer 2000; 83: 1688-95.
-
(2000)
Br J Cancer
, vol.83
, pp. 1688-95
-
-
Deming, S.L.1
Nass, S.J.2
Dickson, R.B.3
Trock, B.J.4
-
5
-
-
0037079027
-
Cyclin E and survival in patients with breast cancer
-
Keyomarsi K, Tucker SL, Buchholz TA et al. Cyclin E and survival in patients with breast cancer. N Engl J Med 2002; 347: 1566-75.
-
(2002)
N Engl J Med
, vol.347
, pp. 1566-75
-
-
Keyomarsi, K.1
Tucker, S.L.2
Buchholz, T.A.3
-
6
-
-
55849100682
-
Fbxw7 in cell cycle exit and stem cell maintenance: insight from gene-targeted mice
-
Onoyama I, Nakayama KI. Fbxw7 in cell cycle exit and stem cell maintenance: insight from gene-targeted mice. Cell Cycle 2008; 7: 3307-13.
-
(2008)
Cell Cycle
, vol.7
, pp. 3307-13
-
-
Onoyama, I.1
Nakayama, K.I.2
-
7
-
-
33646345376
-
Ubiquitin ligases: cell-cycle control and cancer
-
Nakayama KI, Nakayama K. Ubiquitin ligases: cell-cycle control and cancer. Nat Rev Cancer 2006; 6: 369-81.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 369-81
-
-
Nakayama, K.I.1
Nakayama, K.2
-
8
-
-
0842325857
-
Mutation of hCDC4 leads to cell cycle deregulation of cyclin E in cancer
-
Ekholm-Reed S, Spruck CH, Sangfelt O et al. Mutation of hCDC4 leads to cell cycle deregulation of cyclin E in cancer. Cancer Res 2004; 64: 795-800.
-
(2004)
Cancer Res
, vol.64
, pp. 795-800
-
-
Ekholm-Reed, S.1
Spruck, C.H.2
Sangfelt, O.3
-
9
-
-
1542364470
-
Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development
-
Tsunematsu R, Nakayama K, Oike Y et al. Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development. J Biol Chem 2004; 279: 9417-23.
-
(2004)
J Biol Chem
, vol.279
, pp. 9417-23
-
-
Tsunematsu, R.1
Nakayama, K.2
Oike, Y.3
-
10
-
-
36549071481
-
Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis
-
Onoyama I, Tsunematsu R, Matsumoto A et al. Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis. J Exp Med 2007; 204: 2875-88.
-
(2007)
J Exp Med
, vol.204
, pp. 2875-88
-
-
Onoyama, I.1
Tsunematsu, R.2
Matsumoto, A.3
-
11
-
-
35148842479
-
FBXW7/hCDC4 is a general tumor suppressor in human cancer
-
Akhoondi S, Sun D, von der Lehr N et al. FBXW7/hCDC4 is a general tumor suppressor in human cancer. Cancer Res 2007; 67: 9006-12.
-
(2007)
Cancer Res
, vol.67
, pp. 9006-12
-
-
Akhoondi, S.1
Sun, D.2
von der Lehr, N.3
-
12
-
-
42149150460
-
FBXW7 and DNA copy number instability
-
Byrd KN, Huey B, Roydasgupta R, Fridlyand J, Snijders AM, Albertson DG. FBXW7 and DNA copy number instability. Breast Cancer Res Treat 2008; 109: 47-54.
-
(2008)
Breast Cancer Res Treat
, vol.109
, pp. 47-54
-
-
Byrd, K.N.1
Huey, B.2
Roydasgupta, R.3
Fridlyand, J.4
Snijders, A.M.5
Albertson, D.G.6
-
13
-
-
34248221516
-
FBXW7/hCDC4 controls glioma cell proliferation in vitro and is a prognostic marker for survival in glioblastoma patients
-
Hagedorn M, Delugin M, Abraldes I et al. FBXW7/hCDC4 controls glioma cell proliferation in vitro and is a prognostic marker for survival in glioblastoma patients. Cell Div 2007; 2: 9.
-
(2007)
Cell Div
, vol.2
, pp. 9
-
-
Hagedorn, M.1
Delugin, M.2
Abraldes, I.3
-
14
-
-
65949107856
-
p53-Altered FBXW7 expression determines poor prognosis in gastric cancer cases
-
Yokobori T, Mimori K, Iwatsuki M et al. p53-Altered FBXW7 expression determines poor prognosis in gastric cancer cases. Cancer Res 2009; 69: 3788-94.
-
(2009)
Cancer Res
, vol.69
, pp. 3788-94
-
-
Yokobori, T.1
Mimori, K.2
Iwatsuki, M.3
-
15
-
-
77949900799
-
Loss of FBXW7, a cell cycle regulating gene, in colorectal cancer: clinical significance
-
Iwatsuki M, Mimori K, Ishii H et al. Loss of FBXW7, a cell cycle regulating gene, in colorectal cancer: clinical significance. Int J Cancer 2010; 126: 1828-37.
-
(2010)
Int J Cancer
, vol.126
, pp. 1828-37
-
-
Iwatsuki, M.1
Mimori, K.2
Ishii, H.3
-
16
-
-
0035884636
-
Meeting highlights: International Consensus Panel on the Treatment of Primary Breast Cancer. Seventh International Conference on Adjuvant Therapy of Primary Breast Cancer
-
Goldhirsch A, Glick JH, Gelber RD, Coates AS, Senn HJ. Meeting highlights: International Consensus Panel on the Treatment of Primary Breast Cancer. Seventh International Conference on Adjuvant Therapy of Primary Breast Cancer. J Clin Oncol 2001; 19: 3817-27.
-
(2001)
J Clin Oncol
, vol.19
, pp. 3817-27
-
-
Goldhirsch, A.1
Glick, J.H.2
Gelber, R.D.3
Coates, A.S.4
Senn, H.J.5
-
17
-
-
0141576783
-
Meeting highlights: updated international expert consensus on the primary therapy of early breast cancer
-
Goldhirsch A, Wood WC, Gelber RD, Coates AS, Thurlimann B, Senn HJ. Meeting highlights: updated international expert consensus on the primary therapy of early breast cancer. J Clin Oncol 2003; 21: 3357-65.
-
(2003)
J Clin Oncol
, vol.21
, pp. 3357-65
-
-
Goldhirsch, A.1
Wood, W.C.2
Gelber, R.D.3
Coates, A.S.4
Thurlimann, B.5
Senn, H.J.6
-
18
-
-
27244436804
-
Meeting highlights: international expert consensus on the primary therapy of early breast cancer 2005
-
Goldhirsch A, Glick JH, Gelber RD, Coates AS, Thurlimann B, Senn HJ. Meeting highlights: international expert consensus on the primary therapy of early breast cancer 2005. Ann Oncol 2005; 16: 1569-83.
-
(2005)
Ann Oncol
, vol.16
, pp. 1569-83
-
-
Goldhirsch, A.1
Glick, J.H.2
Gelber, R.D.3
Coates, A.S.4
Thurlimann, B.5
Senn, H.J.6
-
19
-
-
34547852275
-
Progress and promise: highlights of the international expert consensus on the primary therapy of early breast cancer 2007
-
Goldhirsch A, Wood WC, Gelber RD, Coates AS, Thurlimann B, Senn HJ. Progress and promise: highlights of the international expert consensus on the primary therapy of early breast cancer 2007. Ann Oncol 2007; 18: 1133-44.
-
(2007)
Ann Oncol
, vol.18
, pp. 1133-44
-
-
Goldhirsch, A.1
Wood, W.C.2
Gelber, R.D.3
Coates, A.S.4
Thurlimann, B.5
Senn, H.J.6
-
20
-
-
46949094778
-
Hypoxia-inducible factor 1alpha is closely linked to an aggressive phenotype in breast cancer
-
Yamamoto Y, Ibusuki M, Okumura Y et al. Hypoxia-inducible factor 1alpha is closely linked to an aggressive phenotype in breast cancer. Breast Cancer Res Treat 2008; 110: 465-75.
-
(2008)
Breast Cancer Res Treat
, vol.110
, pp. 465-75
-
-
Yamamoto, Y.1
Ibusuki, M.2
Okumura, Y.3
-
21
-
-
0026072872
-
Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up
-
Elston CW, Ellis IO. Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. Histopathology 1991; 19: 403-10.
-
(1991)
Histopathology
, vol.19
, pp. 403-10
-
-
Elston, C.W.1
Ellis, I.O.2
-
22
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
-
Sorlie T, Perou CM, Tibshirani R et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A 2001; 98: 10869-74.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 10869-74
-
-
Sorlie, T.1
Perou, C.M.2
Tibshirani, R.3
-
23
-
-
70249116108
-
Genetic susceptibility to the development and progression of breast cancer associated with polymorphism of cell cycle and ubiquitin ligase genes
-
Yu JC, Ding SL, Chang CH et al. Genetic susceptibility to the development and progression of breast cancer associated with polymorphism of cell cycle and ubiquitin ligase genes. Carcinogenesis 2009; 30: 1562-70.
-
(2009)
Carcinogenesis
, vol.30
, pp. 1562-70
-
-
Yu, J.C.1
Ding, S.L.2
Chang, C.H.3
-
24
-
-
55549133237
-
The methylation status of FBXW7 beta-form correlates with histological subtype in human thymoma
-
Gu Z, Mitsui H, Inomata K et al. The methylation status of FBXW7 beta-form correlates with histological subtype in human thymoma. Biochem Biophys Res Commun 2008; 377: 685-8.
-
(2008)
Biochem Biophys Res Commun
, vol.377
, pp. 685-8
-
-
Gu, Z.1
Mitsui, H.2
Inomata, K.3
-
25
-
-
78049392503
-
MicroRNA-223 regulates cyclin E activity by modulating expression of F-box and WD-40 domain protein 7
-
Xu Y, Sengupta T, Kukreja L, Minella AC. MicroRNA-223 regulates cyclin E activity by modulating expression of F-box and WD-40 domain protein 7. J Biol Chem 2010; 285: 34439-46.
-
(2010)
J Biol Chem
, vol.285
, pp. 34439-46
-
-
Xu, Y.1
Sengupta, T.2
Kukreja, L.3
Minella, A.C.4
-
26
-
-
0027280084
-
Expression and amplification of cyclin genes in human breast cancer
-
Buckley MF, Sweeney KJ, Hamilton JA et al. Expression and amplification of cyclin genes in human breast cancer. Oncogene 1993; 8: 2127-33.
-
(1993)
Oncogene
, vol.8
, pp. 2127-33
-
-
Buckley, M.F.1
Sweeney, K.J.2
Hamilton, J.A.3
-
27
-
-
0038024096
-
C-myc, not HER-2/neu, can predict recurrence and mortality of patients with node-negative breast cancer
-
Schlotter CM, Vogt U, Bosse U, Mersch B, Wassmann K. C-myc, not HER-2/neu, can predict recurrence and mortality of patients with node-negative breast cancer. Breast Cancer Res 2003; 5: R30-6.
-
(2003)
Breast Cancer Res
, vol.5
-
-
Schlotter, C.M.1
Vogt, U.2
Bosse, U.3
Mersch, B.4
Wassmann, K.5
-
28
-
-
9244222241
-
Prognostic relevance of gene amplifications and coamplifications in breast cancer
-
Al-Kuraya K, Schraml P, Torhorst J et al. Prognostic relevance of gene amplifications and coamplifications in breast cancer. Cancer Res 2004; 64: 8534-40.
-
(2004)
Cancer Res
, vol.64
, pp. 8534-40
-
-
Al-Kuraya, K.1
Schraml, P.2
Torhorst, J.3
-
29
-
-
0032907690
-
Predictive value of c-erbB-2 and cathepsin-D for Greek breast cancer patients using univariate and multivariate analysis
-
Scorilas A, Yotis J, Pateras C, Trangas T, Talieri M. Predictive value of c-erbB-2 and cathepsin-D for Greek breast cancer patients using univariate and multivariate analysis. Clin Cancer Res 1999; 5: 815-21.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 815-21
-
-
Scorilas, A.1
Yotis, J.2
Pateras, C.3
Trangas, T.4
Talieri, M.5
-
30
-
-
0032795072
-
c-myc, p53 and bcl-2, apoptosis-related genes in infiltrating breast carcinomas: evidence of a link between bcl-2 protein over-expression and a lower risk of metastasis and death in operable patients
-
Le MG, Mathieu MC, Douc-Rasy S et al. c-myc, p53 and bcl-2, apoptosis-related genes in infiltrating breast carcinomas: evidence of a link between bcl-2 protein over-expression and a lower risk of metastasis and death in operable patients. Int J Cancer 1999; 84: 562-7.
-
(1999)
Int J Cancer
, vol.84
, pp. 562-7
-
-
Le, M.G.1
Mathieu, M.C.2
Douc-Rasy, S.3
-
31
-
-
0029054770
-
Oncogene protein co-expression. Value of Ha-ras, c-myc, c-fos, and p53 as prognostic discriminants for breast carcinoma
-
discussion 18-20.
-
Bland KI, Konstadoulakis MM, Vezeridis MP, Wanebo HJ. Oncogene protein co-expression. Value of Ha-ras, c-myc, c-fos, and p53 as prognostic discriminants for breast carcinoma. Ann Surg 1995; 221: 706-18; discussion 18-20.
-
(1995)
Ann Surg
, vol.221
, pp. 706-18
-
-
Bland, K.I.1
Konstadoulakis, M.M.2
Vezeridis, M.P.3
Wanebo, H.J.4
-
32
-
-
33646417913
-
Bcl-2 is a prognostic marker in breast cancer independently of the Nottingham Prognostic Index
-
Callagy GM, Pharoah PD, Pinder SE et al. Bcl-2 is a prognostic marker in breast cancer independently of the Nottingham Prognostic Index. Clin Cancer Res 2006; 12: 2468-75.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 2468-75
-
-
Callagy, G.M.1
Pharoah, P.D.2
Pinder, S.E.3
-
34
-
-
33748855444
-
Cyclin e expression and prognosis in breast cancer patients: a meta-analysis of published studies
-
Wang L, Shao ZM. Cyclin e expression and prognosis in breast cancer patients: a meta-analysis of published studies. Cancer Invest 2006; 24: 581-7.
-
(2006)
Cancer Invest
, vol.24
, pp. 581-7
-
-
Wang, L.1
Shao, Z.M.2
-
35
-
-
0035854820
-
Insulin/insulin-like growth factor-I and estrogen cooperate to stimulate cyclin E-Cdk2 activation and cell Cycle progression in MCF-7 breast cancer cells through differential regulation of cyclin E and p21(WAF1/Cip1)
-
Lai A, Sarcevic B, Prall OW, Sutherland RL. Insulin/insulin-like growth factor-I and estrogen cooperate to stimulate cyclin E-Cdk2 activation and cell Cycle progression in MCF-7 breast cancer cells through differential regulation of cyclin E and p21(WAF1/Cip1). J Biol Chem 2001; 276: 25823-33.
-
(2001)
J Biol Chem
, vol.276
, pp. 25823-33
-
-
Lai, A.1
Sarcevic, B.2
Prall, O.W.3
Sutherland, R.L.4
-
36
-
-
24044525270
-
c-Myc suppresses p21WAF1/CIP1 expression during estrogen signaling and antiestrogen resistance in human breast cancer cells
-
Mukherjee S, Conrad SE. c-Myc suppresses p21WAF1/CIP1 expression during estrogen signaling and antiestrogen resistance in human breast cancer cells. J Biol Chem 2005; 280: 17617-25.
-
(2005)
J Biol Chem
, vol.280
, pp. 17617-25
-
-
Mukherjee, S.1
Conrad, S.E.2
|