Anaesthetic impairment of immune function is mediated via GABAA receptors

PLoS ONE

Volumn 6, Issue 2, 2011, Pages

  Wheeler, Daniel W ^a   Thompson, Andrew J ^a   Corletto, Federico ^a   Reckless, Jill ^b   Loke, Justin C T ^a   Lapaque, Nicolas ^a   Grant, Andrew J ^a   Mastroeni, Pietro ^a   Grainger, David J ^b   Padgett, Claire L ^a   O'Brien, John A ^c   Miller, Nigel G A ^a   Trowsdale, John ^a   Lummis, Sarah C R ^a,c   Menon, David K ^a   Beech, John S ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; PROPOFOL; THIOPENTAL; 4 AMINOBUTYRIC ACID A RECEPTOR STIMULATING AGENT; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; ANESTHETIC AGENT; BICUCULLINE; CYSTEINE LOOP LIGAND GATED ION CHANNEL RECEPTOR; MUSCIMOL; PICROTOXIN;

ANESTHESIA; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; INNATE IMMUNITY; LEUKOCYTE FUNCTION; LEUKOCYTE MIGRATION; MONOCYTE; PATCH CLAMP; PHAGOCYTOSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WHOLE CELL; CELL LINE; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; DRUG POTENTIATION; DRUG SCREENING; GENETICS; IMMUNE SYSTEM; IMMUNOCOMPROMISED PATIENT; IMMUNOLOGY; IMMUNOPATHOLOGY; METABOLISM; PHYSIOLOGY; SYNAPTIC TRANSMISSION;

ANESTHETICS; BICUCULLINE; CELL LINE; CYSTEINE LOOP LIGAND-GATED ION CHANNEL RECEPTORS; DRUG EVALUATION, PRECLINICAL; GABA ANTAGONISTS; GABA-A RECEPTOR AGONISTS; HUMANS; IMMUNE SYSTEM; IMMUNE SYSTEM DISEASES; IMMUNOCOMPROMISED HOST; MONOCYTES; MUSCIMOL; PICROTOXIN; RECEPTORS, GABA-A; SYNAPTIC TRANSMISSION;

EID: 79952081013     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0017152     Document Type: Article

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