메뉴 건너뛰기




Volumn 6, Issue 1, 2010, Pages 711-722

Aliskiren and valsartan combination therapy for the management of hypertension

Author keywords

Aliskiren; Hypertension; Plasma renin activity; Renin angiotensinaldosterone system; Single pill combination; Valsartan

Indexed keywords

ALISKIREN; ALISKIREN PLUS HYDROCHLOROTHIAZIDE; ALISKIREN PLUS VALSARTAN; AMLODIPINE; ANGIOTENSIN RECEPTOR ANTAGONIST; ATENOLOL; BENAZEPRIL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BRAIN NATRIURETIC PEPTIDE; CALCIUM CHANNEL BLOCKING AGENT; CANDESARTAN; CAPTOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; EPLERENONE; IRBESARTAN; LISINOPRIL; LOSARTAN; PLACEBO; RAMIPRIL; TELMISARTAN; THIAZIDE DIURETIC AGENT; VALSARTAN; AMIDE; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANTIHYPERTENSIVE AGENT; DRUG DERIVATIVE; FUMARIC ACID DERIVATIVE; TETRAZOLE DERIVATIVE; VALINE;

EID: 79952057601     PISSN: 11766344     EISSN: 11782048     Source Type: Journal    
DOI: 10.2147/vhrm.s8175     Document Type: Review
Times cited : (16)

References (73)
  • 2
    • 0037079309 scopus 로고    scopus 로고
    • Age-specific relevance of usual blood pressure to vascular mortality: A meta-analysis of individual data for one million adults in 61 prospective studies
    • Lewington S, Clarke R, Qizilbash N, Peto R, Collins R. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet. 2002;360(9349):1903-1913.
    • (2002) Lancet , vol.360 , Issue.9349 , pp. 1903-1913
    • Lewington, S.1    Clarke, R.2    Qizilbash, N.3    Peto, R.4    Collins, R.5
  • 3
    • 0035522330 scopus 로고    scopus 로고
    • Impact of high-normal blood pressure on the risk of cardiovascular disease
    • Vasan RS, Larson MG, Leip EP, et al. Impact of high-normal blood pressure on the risk of cardiovascular disease. N Engl J Med. 2001;345(18):1291-1297.
    • (2001) N Engl J Med , vol.345 , Issue.18 , pp. 1291-1297
    • Vasan, R.S.1    Larson, M.G.2    Leip, E.P.3
  • 4
    • 0037429639 scopus 로고    scopus 로고
    • Management of high blood pressure in African Americans: Consensus statement of the Hypertension in African Americans Working Group of the International Society on Hypertension in Blacks
    • Douglas JG, Bakris GL, Epstein M, et al. Management of high blood pressure in African Americans: consensus statement of the Hypertension in African Americans Working Group of the International Society on Hypertension in Blacks. Arch Intern Med. 2003;163(5):525-541.
    • (2003) Arch Intern Med , vol.163 , Issue.5 , pp. 525-541
    • Douglas, J.G.1    Bakris, G.L.2    Epstein, M.3
  • 5
    • 0347423198 scopus 로고    scopus 로고
    • Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure
    • Chobanian AV, Bakris GL, Black HR, et al. Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension. 2003;42(6):1206-1252.
    • (2003) Hypertension , vol.42 , Issue.6 , pp. 1206-1252
    • Chobanian, A.V.1    Bakris, G.L.2    Black, H.R.3
  • 6
    • 33847633400 scopus 로고    scopus 로고
    • Prevalence, awareness, treatment, and control of hypertension among United States adults 1999-2004
    • Ong KL, Cheung BM, Man YB, Lau CP, Lam KS. Prevalence, awareness, treatment, and control of hypertension among United States adults 1999-2004. Hypertension. 2007;49(1):69-75.
    • (2007) Hypertension , vol.49 , Issue.1 , pp. 69-75
    • Ong, K.L.1    Cheung, B.M.2    Man, Y.B.3    Lau, C.P.4    Lam, K.S.5
  • 7
    • 37149026076 scopus 로고    scopus 로고
    • Inadequate control of hypertension in US adults with cardiovascular disease comorbidities in 2003-2004
    • Wong ND, Lopez VA, L'Italien G, Chen R, Kline SE, Franklin SS. Inadequate control of hypertension in US adults with cardiovascular disease comorbidities in 2003-2004. Arch Intern Med. 2007; 167(22):2431-2436.
    • (2007) Arch Intern Med , vol.167 , Issue.22 , pp. 2431-2436
    • Wong, N.D.1    Lopez, V.A.2    L'italien, G.3    Chen, R.4    Kline, S.E.5    Franklin, S.S.6
  • 8
    • 0036863587 scopus 로고    scopus 로고
    • Success and predictors of blood pressure control in diverse North American settings: The antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT)
    • Cushman WC, Ford CE, Cutler JA, et al. Success and predictors of blood pressure control in diverse North American settings: the antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT). J Clin Hypertens (Greenwich). 2002;4(6):393-404.
    • (2002) J Clin Hypertens (Greenwich) , vol.4 , Issue.6 , pp. 393-404
    • Cushman, W.C.1    Ford, C.E.2    Cutler, J.A.3
  • 9
    • 24644443331 scopus 로고    scopus 로고
    • Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): A multicentre randomised controlled trial
    • Dahlöf B, Sever PS, Poulter NR, et al. Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled trial. Lancet. 2005;366(9489):895-906.
    • (2005) Lancet , vol.366 , Issue.9489 , pp. 895-906
    • Dahlöf, B.1    Sever, P.S.2    Poulter, N.R.3
  • 10
    • 0037145856 scopus 로고    scopus 로고
    • Effect of blood pressure lowering and antihypertensive drug class on progression of hypertensive kidney disease: Results from the AASK trial
    • Wright JT Jr, Bakris G, Greene T, et al. Effect of blood pressure lowering and antihypertensive drug class on progression of hypertensive kidney disease: results from the AASK trial. JAMA. 2002; 288(19):2421-2431.
    • (2002) JAMA , vol.288 , Issue.19 , pp. 2421-2431
    • Wright Jr., J.T.1    Bakris, G.2    Greene, T.3
  • 11
    • 70449851433 scopus 로고    scopus 로고
    • Reappraisal of European guidelines on hypertension management: A European Society of Hypertension Task Force document
    • Mancia G, Laurent S, Agabiti-Rosei E, et al. Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document. J Hypertens. 2009;27:2121-2158.
    • (2009) J Hypertens , vol.27 , pp. 2121-2158
    • Mancia, G.1    Laurent, S.2    Agabiti-Rosei, E.3
  • 12
    • 58049112068 scopus 로고    scopus 로고
    • Combining RAAS and calcium channel blockade: ACCOMPLISH in perspective
    • Kjeldsen SE, Weber M, Oparil S, Jamerson KA. Combining RAAS and calcium channel blockade: ACCOMPLISH in perspective. Blood Press. 2008;17(5-6):260-269.
    • (2008) Blood Press , vol.17 , Issue.5-6 , pp. 260-269
    • Kjeldsen, S.E.1    Weber, M.2    Oparil, S.3    Jamerson, K.A.4
  • 13
    • 57349138291 scopus 로고    scopus 로고
    • Benazepril plus amlodipine or hydrochlorothiazide for hypertension in high-risk patients
    • Jamerson K, Weber MA, Bakris GL, et al. Benazepril plus amlodipine or hydrochlorothiazide for hypertension in high-risk patients. N Engl J Med. 2008;359(23):2417-2428.
    • (2008) N Engl J Med , vol.359 , Issue.23 , pp. 2417-2428
    • Jamerson, K.1    Weber, M.A.2    Bakris, G.L.3
  • 14
    • 2942695964 scopus 로고    scopus 로고
    • Blood pressure dependent and independent effects of antihypertensive treatment on clinical events in the VALUE Trial
    • Weber MA, Julius S, Kjeldsen SE, et al. Blood pressure dependent and independent effects of antihypertensive treatment on clinical events in the VALUE Trial. Lancet. 2004;363(9426):2049-2051.
    • (2004) Lancet , vol.363 , Issue.9426 , pp. 2049-2051
    • Weber, M.A.1    Julius, S.2    Kjeldsen, S.E.3
  • 15
    • 11144356621 scopus 로고    scopus 로고
    • Effects of immediate versus delayed antihypertensive therapy on outcome in the Systolic Hypertension in Europe Trial
    • Staessen JA, Thijisq L, Fagard R, et al. Effects of immediate versus delayed antihypertensive therapy on outcome in the Systolic Hypertension in Europe Trial. J Hypertens. 2004;22(4):847-857.
    • (2004) J Hypertens , vol.22 , Issue.4 , pp. 847-857
    • Staessen, J.A.1    Thijisq, L.2    Fagard, R.3
  • 16
    • 33845902544 scopus 로고    scopus 로고
    • The cardiovascular disease continuum validated: Clinical evidence of improved patient outcomes: Part I: Pathophysiology and clinical trial evidence (risk factors through stable coronary artery disease)
    • Dzau VJ, Antman EM, Black HR, et al. The cardiovascular disease continuum validated: clinical evidence of improved patient outcomes: part I: pathophysiology and clinical trial evidence (risk factors through stable coronary artery disease). Circulation. 2006;114(25): 2850-2870.
    • (2006) Circulation , vol.114 , Issue.25 , pp. 2850-2870
    • Dzau, V.J.1    Antman, E.M.2    Black, H.R.3
  • 17
    • 0035048905 scopus 로고    scopus 로고
    • Theodore Cooper Lecture: Tissue angiotensin and pathobiology of vascular disease: A unifying hypothesis
    • Dzau VJ. Theodore Cooper Lecture: Tissue angiotensin and pathobiology of vascular disease: a unifying hypothesis. Hypertension. 2001;37(4):1047-1052.
    • (2001) Hypertension , vol.37 , Issue.4 , pp. 1047-1052
    • Dzau, V.J.1
  • 18
    • 0022271856 scopus 로고
    • End-state renal failure in diabetic nephropathy: Pathophysiology and treatment
    • Schmitz O, Hansen HE, Orskov H, Mogensen CE, Posborg Petersen V. End-state renal failure in diabetic nephropathy: pathophysiology and treatment. Blood Purif. 1985;3(1-3):120-139.
    • (1985) Blood Purif , vol.3 , Issue.1-3 , pp. 120-139
    • Schmitz, O.1    Hansen, H.E.2    Orskov, H.3    Mogensen, C.E.4    Posborg, P.V.5
  • 19
    • 0035922441 scopus 로고    scopus 로고
    • Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
    • Brenner BM, Cooper ME, de Zeeuw D, et al. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med. 2001;345(12):861-869.
    • (2001) N Engl J Med , vol.345 , Issue.12 , pp. 861-869
    • Brenner, B.M.1    Cooper, M.E.2    de Zeeuw, D.3
  • 21
  • 22
    • 77955928113 scopus 로고    scopus 로고
    • Plasma renin activity is associated with increased cardiovascular events and mortality in the HOPE study
    • Abstract 1134
    • Verma S, Gupta M, Holmes DT, et al. 2009. Plasma renin activity is associated with increased cardiovascular events and mortality in the HOPE study. Circulation. 120:S453. Abstract 1134.
    • (2009) Circulation , vol.120
    • Verma, S.1    Gupta, M.2    Holmes, D.T.3
  • 23
    • 70349218543 scopus 로고    scopus 로고
    • Association between baseline levels of plasma renin activity and risk of cardiovascular events
    • Abstract 1028-12
    • Bair TL, May HT, Prescott MF, et al. 2009. Association between baseline levels of plasma renin activity and risk of cardiovascular events. J Am Coll Cardiol. 53(10 Suppl A):A383. Abstract 1028-12.
    • (2009) J Am Coll Cardiol , vol.53 , Issue.10 SUPPL A
    • Bair, T.L.1    May, H.T.2    Prescott, M.F.3
  • 24
    • 72549105303 scopus 로고    scopus 로고
    • Aldosterone and cardiovascular risk
    • Vogt B, Burnier M. Aldosterone and cardiovascular risk. Curr Hypertens Rep. 2009;11(6):450-455.
    • (2009) Curr Hypertens Rep , vol.11 , Issue.6 , pp. 450-455
    • Vogt, B.1    Burnier, M.2
  • 25
    • 33646580336 scopus 로고    scopus 로고
    • ACE inhibitor-angiotensin receptor blocker combinations: A clinician's perspective
    • Doulton TW. ACE inhibitor-angiotensin receptor blocker combinations: a clinician's perspective. Mini Rev Med Chem. 2006;6(5):491-497.
    • (2006) Mini Rev Med Chem , vol.6 , Issue.5 , pp. 491-497
    • Doulton, T.W.1
  • 26
    • 73349128134 scopus 로고    scopus 로고
    • Recent changes in the landscape of combination RAS blockade
    • Epstein BJ, Smith SM, Choksi R. Recent changes in the landscape of combination RAS blockade. Expert Rev Cardiovasc Ther. 2009;7(11):1373-1384.
    • (2009) Expert Rev Cardiovasc Ther , vol.7 , Issue.11 , pp. 1373-1384
    • Epstein, B.J.1    Smith, S.M.2    Choksi, R.3
  • 27
    • 36349036058 scopus 로고    scopus 로고
    • Aldosterone breakthrough during angiotensin II receptor blockade in hypertensive patients with diabetes mellitus
    • Yoneda T, Takeda Y, Usukura M, et al. Aldosterone breakthrough during angiotensin II receptor blockade in hypertensive patients with diabetes mellitus. Am J Hypertens. 2007;20(12):1329-1333.
    • (2007) Am J Hypertens , vol.20 , Issue.12 , pp. 1329-1333
    • Yoneda, T.1    Takeda, Y.2    Usukura, M.3
  • 28
    • 34548163060 scopus 로고    scopus 로고
    • The incidence and implications of aldosterone breakthrough
    • Bomback AS, Klemmer PJ. The incidence and implications of aldosterone breakthrough. Nat Clin Pract Nephrol. 2007;3(9):486-492.
    • (2007) Nat Clin Pract Nephrol , vol.3 , Issue.9 , pp. 486-492
    • Bomback, A.S.1    Klemmer, P.J.2
  • 29
    • 73349127055 scopus 로고    scopus 로고
    • Aliskiren, the first approved renin inhibitor: Clinical application and safety in the treatment of hypertension
    • Riccioni G, Vitulano N, D'Orazio N, Bellocci F. Aliskiren, the first approved renin inhibitor: Clinical application and safety in the treatment of hypertension. Adv Ther. 2009;26(7):700-710.
    • (2009) Adv Ther , vol.26 , Issue.7 , pp. 700-710
    • Riccioni, G.1    Vitulano, N.2    D'orazio, N.3    Bellocci, F.4
  • 30
    • 18244406792 scopus 로고    scopus 로고
    • Systematic review of combined angiotensin-converting enzyme inhibition and angiotensin receptor blockade in hypertension
    • Doulton TW, He FJ, MacGregor GA. Systematic review of combined angiotensin-converting enzyme inhibition and angiotensin receptor blockade in hypertension. Hypertension. 2005;45(5):880-886.
    • (2005) Hypertension , vol.45 , Issue.5 , pp. 880-886
    • Doulton, T.W.1    He, F.J.2    Macgregor, G.A.3
  • 31
    • 42049107348 scopus 로고    scopus 로고
    • Telmisartan, ramipril, or both in patients at high risk for vascular events
    • Yusuf S, Teo KK, Pogue J, et al. Telmisartan, ramipril, or both in patients at high risk for vascular events. N Engl J Med. 2008; 358(15): 1547-1559.
    • (2008) N Engl J Med , vol.358 , Issue.15 , pp. 1547-1559
    • Yusuf, S.1    Teo, K.K.2    Pogue, J.3
  • 32
    • 49149087718 scopus 로고    scopus 로고
    • Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): A multicentre, randomised, double-blind, controlled trial
    • Mann JF, Schmieder RE, McQueen M, et al. Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): a multicentre, randomised, double-blind, controlled trial. Lancet. 2008;372(9638):547-553.
    • (2008) Lancet , vol.372 , Issue.9638 , pp. 547-553
    • Mann, J.F.1    Schmieder, R.E.2    McQueen, M.3
  • 33
    • 34548444609 scopus 로고    scopus 로고
    • Albuminuria response to very high-dose valsartan in type 2 diabetes mellitus
    • Hollenberg NK, Parving HH, Viberti G, et al. Albuminuria response to very high-dose valsartan in type 2 diabetes mellitus. J Hypertens. 2007;25(9):1921-1926.
    • (2007) J Hypertens , vol.25 , Issue.9 , pp. 1921-1926
    • Hollenberg, N.K.1    Parving, H.H.2    Viberti, G.3
  • 34
    • 36248931664 scopus 로고    scopus 로고
    • The renin-angiotensin aldosterone system: Pathophysiological role and pharmacologic inhibition
    • Atlas SA. The renin-angiotensin aldosterone system: pathophysiological role and pharmacologic inhibition. J Manag Care Pharm. 2007; 13(8 Suppl S-b):S9-S20.
    • (2007) J Manag Care Pharm , vol.13 , Issue.8 SUPPL S-B
    • Atlas, S.A.1
  • 35
    • 0028017360 scopus 로고
    • Prognostic value of neurohumoral activation in patients with an acute myocardial infarction: Effect of captopril
    • Rouleau JL, Packer M, Moye L, et al. Prognostic value of neurohumoral activation in patients with an acute myocardial infarction: effect of captopril. J Am Coll Cardiol. 1994;24(3):583-591.
    • (1994) J Am Coll Cardiol , vol.24 , Issue.3 , pp. 583-591
    • Rouleau, J.L.1    Packer, M.2    Moye, L.3
  • 36
    • 10744232800 scopus 로고    scopus 로고
    • The comparative prognostic value of plasma neurohormones at baseline in patients with heart failure enrolled in Val-HeFT
    • Latini R, Masson S, Anand I, et al. The comparative prognostic value of plasma neurohormones at baseline in patients with heart failure enrolled in Val-HeFT. Eur Heart J. 2004;25(4):292-299.
    • (2004) Eur Heart J , vol.25 , Issue.4 , pp. 292-299
    • Latini, R.1    Masson, S.2    Anand, I.3
  • 37
    • 33846421005 scopus 로고    scopus 로고
    • Aliskiren reduces blood pressure and suppresses plasma renin activity in combination with a thiazide diuretic, an angiotensin-converting enzyme inhibitor, or an angiotensin receptor blocker
    • O'Brien E, Barton J, Nussberger J, et al. Aliskiren reduces blood pressure and suppresses plasma renin activity in combination with a thiazide diuretic, an angiotensin-converting enzyme inhibitor, or an angiotensin receptor blocker. Hypertension. 2007;49(2):276-284.
    • (2007) Hypertension , vol.49 , Issue.2 , pp. 276-284
    • O'Brien, E.1    Barton, J.2    Nussberger, J.3
  • 38
    • 38649102508 scopus 로고    scopus 로고
    • Efficacy and safety of the direct renin inhibitor aliskiren and ramipril alone or in combination in patients with diabetes and hypertension
    • Uresin Y, Taylor AA, Kilo C, et al. Efficacy and safety of the direct renin inhibitor aliskiren and ramipril alone or in combination in patients with diabetes and hypertension. J Renin Angiotensin Aldosterone Syst. 2007;8(4):190-198.
    • (2007) J Renin Angiotensin Aldosterone Syst , vol.8 , Issue.4 , pp. 190-198
    • Uresin, Y.1    Taylor, A.A.2    Kilo, C.3
  • 39
    • 47049093197 scopus 로고    scopus 로고
    • Renal and hormonal responses to direct renin inhibition with aliskiren in healthy humans
    • Fisher ND, Jan Danser AH, Nussberger J, Dole WP, Hollenberg NK. Renal and hormonal responses to direct renin inhibition with aliskiren in healthy humans. Circulation. 2008;117(25):3199-3205.
    • (2008) Circulation , vol.117 , Issue.25 , pp. 3199-3205
    • Fisher, N.D.1    Jan, D.A.H.2    Nussberger, J.3    Dole, W.P.4    Hollenberg, N.K.5
  • 40
    • 70349690296 scopus 로고    scopus 로고
    • Renal effects of aliskiren compared to and in combination with irbesartan in patients with type 2 diabetes, hypertension and albuminuria
    • Persson F, Rossing P, Reinhard H, et al. Renal effects of aliskiren compared to and in combination with irbesartan in patients with type 2 diabetes, hypertension and albuminuria. Diabetes Care. 2009;32(10): 1873-1879.
    • (2009) Diabetes Care , vol.32 , Issue.10 , pp. 1873-1879
    • Persson, F.1    Rossing, P.2    Reinhard, H.3
  • 41
    • 79958249630 scopus 로고    scopus 로고
    • Effects of the oral direct rennin inhibitor aliskiren in patients with symptomatic heart failure
    • McMurray JJ, Pitt B, Latini R, et al. Effects of the oral direct rennin inhibitor aliskiren in patients with symptomatic heart failure. Circ Heart Fail. 2008;1:17-24.
    • (2008) Circ Heart Fail , vol.1 , pp. 17-24
    • McMurray, J.J.1    Pitt, B.2    Latini, R.3
  • 42
    • 61349170589 scopus 로고    scopus 로고
    • Effect of the direct renin inhibitor aliskiren, the angiotensin receptor blocker losartan, or both on left ventricular mass in patients with hypertension and left ventricular hypertrophy
    • Solomon SD, Appelbaum E, Manning WJ, et al. Effect of the direct renin inhibitor aliskiren, the angiotensin receptor blocker losartan, or both on left ventricular mass in patients with hypertension and left ventricular hypertrophy. Circulation. 2009;119(4):530-537.
    • (2009) Circulation , vol.119 , Issue.4 , pp. 530-537
    • Solomon, S.D.1    Appelbaum, E.2    Manning, W.J.3
  • 43
    • 36649012323 scopus 로고    scopus 로고
    • Renin system suppression with the oral direct renin inhibitor aliskiren administered alone or in combination: A pooled analysis of 1093 patients with hypertension
    • Abstract 1014-1170
    • Taylor AA, Anderson DR, Arora V, et al. 2007. Renin system suppression with the oral direct renin inhibitor aliskiren administered alone or in combination: a pooled analysis of 1093 patients with hypertension. J Am Coll Cardiol. 49(9 Suppl A):370A. Abstract 1014-1170.
    • (2007) J Am Coll Cardiol , vol.49 , Issue.9 SUPPL A
    • Taylor, A.A.1    Anderson, D.R.2    Arora, V.3
  • 44
    • 9644287897 scopus 로고    scopus 로고
    • Pharmacologic demonstration of the synergistic effects of a combination of the renin inhibitor aliskiren and the AT1 receptor antagonist valsartan on the angiotensin II-renin feedback interruption
    • Azizi M, Ménard J, Bissery A, et al. Pharmacologic demonstration of the synergistic effects of a combination of the renin inhibitor aliskiren and the AT1 receptor antagonist valsartan on the angiotensin II-renin feedback interruption. J Am Soc Nephrol. 2004;15(12):3126-3133.
    • (2004) J Am Soc Nephrol , vol.15 , Issue.12 , pp. 3126-3133
    • Azizi, M.1    Ménard, J.2    Bissery, A.3
  • 45
    • 69849112971 scopus 로고    scopus 로고
    • Comparative effects of aliskiren-based and ramipril-based therapy on the renin system during long-term (6 months) treatment and withdrawal in patients with hypertension
    • Andersen K, Weinberger MH, Constance CC, et al. Comparative effects of aliskiren-based and ramipril-based therapy on the renin system during long-term (6 months) treatment and withdrawal in patients with hypertension. J Renin Angiotensin Aldosterone Syst. 2009;10(3):157-167.
    • (2009) J Renin Angiotensin Aldosterone Syst , vol.10 , Issue.3 , pp. 157-167
    • Andersen, K.1    Weinberger, M.H.2    Constance, C.C.3
  • 47
    • 34447521458 scopus 로고    scopus 로고
    • Efficacy and safety of combined use of aliskiren and valsartan in patients with hypertension: A randomised, double-blind trial
    • Oparil S, Yarows SA, Patel S, Fang H, Zhang J, Satlin A. Efficacy and safety of combined use of aliskiren and valsartan in patients with hypertension: a randomised, double-blind trial. Lancet. 2007;370(9583):221-229.
    • (2007) Lancet , vol.370 , Issue.9583 , pp. 221-229
    • Oparil, S.1    Yarows, S.A.2    Patel, S.3    Fang, H.4    Zhang, J.5    Satlin, A.6
  • 48
    • 69849114573 scopus 로고    scopus 로고
    • Aliskiren and valsartan in stage 2 hypertension: Subgroup analysis of a randomized, doubleblind study
    • Yarows SA, Oparil S, Patel S, Fang H, Zhang J. Aliskiren and valsartan in stage 2 hypertension: subgroup analysis of a randomized, doubleblind study. Adv Ther. 2008;25(12):1288-1302.
    • (2008) Adv Ther , vol.25 , Issue.12 , pp. 1288-1302
    • Yarows, S.A.1    Oparil, S.2    Patel, S.3    Fang, H.4    Zhang, J.5
  • 49
    • 42549113198 scopus 로고    scopus 로고
    • Long-term safety, tolerability and efficacy of aliskiren in combination with valsartan in patients with hypertension: A 6-month interim analysis
    • Chrysant SG, Murray AV, Hoppe UC, et al. Long-term safety, tolerability and efficacy of aliskiren in combination with valsartan in patients with hypertension: a 6-month interim analysis. Curr Med Res Opin. 2008;24(4):1039-1047.
    • (2008) Curr Med Res Opin , vol.24 , Issue.4 , pp. 1039-1047
    • Chrysant, S.G.1    Murray, A.V.2    Hoppe, U.C.3
  • 50
    • 33845785350 scopus 로고    scopus 로고
    • Aliskiren, an orally effective renin inhibitor, provides antihypertensive efficacy alone and in combination with valsartan
    • Pool JL, Schmieder RE, Azizi M, et al. Aliskiren, an orally effective renin inhibitor, provides antihypertensive efficacy alone and in combination with valsartan. Am J Hypertens. 2007;20(1):11-20.
    • (2007) Am J Hypertens , vol.20 , Issue.1 , pp. 11-20
    • Pool, J.L.1    Schmieder, R.E.2    Azizi, M.3
  • 51
    • 34250179723 scopus 로고    scopus 로고
    • Fixed-dose combinations improve medication compliance: A meta-analysis
    • Bangalore S, Kamalakkannan G, Parkar S, Messerli FH. Fixed-dose combinations improve medication compliance: a meta-analysis. Am J Med. 2007;120(8):713-719.
    • (2007) Am J Med , vol.120 , Issue.8 , pp. 713-719
    • Bangalore, S.1    Kamalakkannan, G.2    Parkar, S.3    Messerli, F.H.4
  • 52
    • 64149083424 scopus 로고    scopus 로고
    • Issues in blood pressure control and the potential role of single-pill combination therapies
    • Burnier M, Brown RE, Ong SH, Keskinaslan A, Khan ZM. Issues in blood pressure control and the potential role of single-pill combination therapies. Int J Clin Pract. 2009;63(5):790-798.
    • (2009) Int J Clin Pract , vol.63 , Issue.5 , pp. 790-798
    • Burnier, M.1    Brown, R.E.2    Ong, S.H.3    Keskinaslan, A.4    Khan, Z.M.5
  • 53
    • 60549100908 scopus 로고    scopus 로고
    • An issue of dependence: Implications from the Aliskiren in the Evaluation of Proteinuria in Diabetes (AVOID) trial
    • Riche DM, Minor DS, Holdiness AS, East HE. An issue of dependence: implications from the Aliskiren in the Evaluation of Proteinuria in Diabetes (AVOID) trial. J Clin Hypertens (Greenwich). 2009;11(2):89-93.
    • (2009) J Clin Hypertens (Greenwich) , vol.11 , Issue.2 , pp. 89-93
    • Riche, D.M.1    Minor, D.S.2    Holdiness, A.S.3    East, H.E.4
  • 54
    • 0037417252 scopus 로고    scopus 로고
    • Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction
    • Pitt B, Remme W, Zannad F, et al. Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction. N Engl J Med. 2003;348(14):1309-1321.
    • (2003) N Engl J Med , vol.348 , Issue.14 , pp. 1309-1321
    • Pitt, B.1    Remme, W.2    Zannad, F.3
  • 55
    • 0033517302 scopus 로고    scopus 로고
    • The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators
    • Pitt B, Zannad F, Remme WJ, et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med. 1999;341(10):709-717.
    • (1999) N Engl J Med , vol.341 , Issue.10 , pp. 709-717
    • Pitt, B.1    Zannad, F.2    Remme, W.J.3
  • 56
    • 0037116558 scopus 로고    scopus 로고
    • Addition of spironolactone to angiotensin-converting enzyme inhibition in heart failure improves endothelial vasomotor dysfunction: Role of vascular superoxide anion formation and endothelial nitric oxide synthase expression
    • Bauersachs J, Heck M, Fraccarollo D, et al. Addition of spironolactone to angiotensin-converting enzyme inhibition in heart failure improves endothelial vasomotor dysfunction: role of vascular superoxide anion formation and endothelial nitric oxide synthase expression. J Am Coll Cardiol. 2002;39(2):351-358.
    • (2002) J Am Coll Cardiol , vol.39 , Issue.2 , pp. 351-358
    • Bauersachs, J.1    Heck, M.2    Fraccarollo, D.3
  • 57
    • 0037035471 scopus 로고    scopus 로고
    • Mineralocorticoid receptor antagonism in experimental atherosclerosis
    • Rajagopalan S, Duquaine D, King S, Pitt B, Patel P. Mineralocorticoid receptor antagonism in experimental atherosclerosis. Circulation. 2002;105(18):2212-2216.
    • (2002) Circulation , vol.105 , Issue.18 , pp. 2212-2216
    • Rajagopalan, S.1    Duquaine, D.2    King, S.3    Pitt, B.4    Patel, P.5
  • 58
    • 65249182083 scopus 로고    scopus 로고
    • Aliskiren Trial in Type 2 Diabetes Using Cardio-Renal Endpoints (ALTITUDE): Rationale and study design
    • Parving HH, Brenner BM, McMurray JJ, et al. Aliskiren Trial in Type 2 Diabetes Using Cardio-Renal Endpoints (ALTITUDE): rationale and study design. Nephrol Dial Transplant. 2009;24(5):1663-1671.
    • (2009) Nephrol Dial Transplant , vol.24 , Issue.5 , pp. 1663-1671
    • Parving, H.H.1    Brenner, B.M.2    McMurray, J.J.3
  • 59
    • 66149177166 scopus 로고    scopus 로고
    • Cardio-renal protection with aliskiren, a direct renin inhibitor, in the ASPIRE HIGHER program
    • Lee HY, Oh BH. Cardio-renal protection with aliskiren, a direct renin inhibitor, in the ASPIRE HIGHER program. Expert Rev Cardiovasc Ther. 2009;7(3):251-257.
    • (2009) Expert Rev Cardiovasc Ther , vol.7 , Issue.3 , pp. 251-257
    • Lee, H.Y.1    Oh, B.H.2
  • 61
    • 36248931230 scopus 로고    scopus 로고
    • Antihypertensive efficacy of the oral direct renin inhibitor aliskiren as add-on therapy in patients not responding to amlodipine monotherapy
    • Drummond W, Munger MA, Rafique EM, Maboudian M, Khan M, Keefe DL. Antihypertensive efficacy of the oral direct renin inhibitor aliskiren as add-on therapy in patients not responding to amlodipine monotherapy. J Clin Hypertens (Greenwich). 2007;9(10):742-750.
    • (2007) J Clin Hypertens (Greenwich) , vol.9 , Issue.10 , pp. 742-750
    • Drummond, W.1    Munger, M.A.2    Rafique, E.M.3    Maboudian, M.4    Khan, M.5    Keefe, D.L.6
  • 62
    • 33845366982 scopus 로고    scopus 로고
    • Renin inhibition with aliskiren provides additive antihypertensive efficacy when used in combination with hydrochlorothiazide
    • Villamil A, Chrysant SG, Calhoun D, et al. Renin inhibition with aliskiren provides additive antihypertensive efficacy when used in combination with hydrochlorothiazide. J Hypertens. 2007;25(1):217-226.
    • (2007) J Hypertens , vol.25 , Issue.1 , pp. 217-226
    • Villamil, A.1    Chrysant, S.G.2    Calhoun, D.3
  • 63
    • 0034688194 scopus 로고    scopus 로고
    • Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators
    • Yusuf S, Sleight P, Pogue J, Bosch J, Davies R, Dagenais G. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med. 2000;342(3):145-153.
    • (2000) N Engl J Med , vol.342 , Issue.3 , pp. 145-153
    • Yusuf, S.1    Sleight, P.2    Pogue, J.3    Bosch, J.4    Davies, R.5    Dagenais, G.6
  • 64
    • 0023266532 scopus 로고
    • Effects of enalapril on mortality in severe congestive heart failure. Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS)
    • The CONSENSUS Trial Study Group
    • Effects of enalapril on mortality in severe congestive heart failure. Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). The CONSENSUS Trial Study Group. N Engl J Med. 1987;316(23):1429-1435.
    • (1987) N Engl J Med , vol.316 , Issue.23 , pp. 1429-1435
  • 65
    • 0025913812 scopus 로고
    • Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure
    • The SOLVD Investigators
    • Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. The SOLVD Investigators. N Engl J Med. 1991;325(5):293-302.
    • (1991) N Engl J Med , vol.325 , Issue.5 , pp. 293-302
  • 66
    • 0035818884 scopus 로고    scopus 로고
    • A randomized trial of the angiotensinreceptor blocker valsartan in chronic heart failure
    • Cohn JN, Tognoni G. A randomized trial of the angiotensinreceptor blocker valsartan in chronic heart failure. N Engl J Med. 2001;345(23):1667-1675.
    • (2001) N Engl J Med , vol.345 , Issue.23 , pp. 1667-1675
    • Cohn, J.N.1    Tognoni, G.2
  • 67
    • 0037160968 scopus 로고    scopus 로고
    • Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): A randomised trial against atenolol
    • Dahlöf B, Devereux RB, Kjeldsen SE, et al. Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol. Lancet. 2002;359(9311):995-1003.
    • (2002) Lancet , vol.359 , Issue.9311 , pp. 995-1003
    • Dahlöf, B.1    Devereux, R.B.2    Kjeldsen, S.E.3
  • 68
    • 0041909380 scopus 로고    scopus 로고
    • Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function intolerant to angiotensin-converting-enzyme inhibitors: The CHARM-Alternative trial
    • Granger CB, McMurray JJ, Yusuf S, et al. Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function intolerant to angiotensin-converting-enzyme inhibitors: the CHARM-Alternative trial. Lancet. 2003;362(9386):772-776.
    • (2003) Lancet , vol.362 , Issue.9386 , pp. 772-776
    • Granger, C.B.1    McMurray, J.J.2    Yusuf, S.3
  • 69
    • 0035922447 scopus 로고    scopus 로고
    • Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes
    • Lewis EJ, Hunsicker LG, Clarke WR, et al. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med. 2001;345(12):851-860.
    • (2001) N Engl J Med , vol.345 , Issue.12 , pp. 851-860
    • Lewis, E.J.1    Hunsicker, L.G.2    Clarke, W.R.3
  • 70
    • 0242490542 scopus 로고    scopus 로고
    • Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both
    • Pfeffer MA, McMurray JJ, Velazquez EJ, et al. Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both. N Engl J Med. 2003;349(20):1893-1906.
    • (2003) N Engl J Med , vol.349 , Issue.20 , pp. 1893-1906
    • Pfeffer, M.A.1    McMurray, J.J.2    Velazquez, E.J.3
  • 71
    • 0041408235 scopus 로고    scopus 로고
    • Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: The CHARM-Added trial
    • McMurray JJ, Ostergren J, Swedberg K, et al. Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: the CHARM-Added trial. Lancet. 2003;362(9386):767-771.
    • (2003) Lancet , vol.362 , Issue.9386 , pp. 767-771
    • McMurray, J.J.1    Ostergren, J.2    Swedberg, K.3
  • 72
    • 0034627208 scopus 로고    scopus 로고
    • Randomised controlled trial of dual blockade of renin-angiotensin system in patients with hypertension, microalbuminuria, and non-insulin dependent diabetes: The candesartan and lisinopril microalbuminuria (CALM) study
    • Mogensen CE, Neldam S, Tikkanen I, et al. Randomised controlled trial of dual blockade of renin-angiotensin system in patients with hypertension, microalbuminuria, and non-insulin dependent diabetes: the candesartan and lisinopril microalbuminuria (CALM) study. BMJ. 2000;321(7274):1440-1444.
    • (2000) BMJ , vol.321 , Issue.7274 , pp. 1440-1444
    • Mogensen, C.E.1    Neldam, S.2    Tikkanen, I.3
  • 73
    • 34648820103 scopus 로고    scopus 로고
    • Treatment of microalbuminuria in hypertensive subjects with elevated cardiovascular risk: Results of the IMPROVE trial
    • Bakris GL, Ruilope L, Locatelli F, et al. Treatment of microalbuminuria in hypertensive subjects with elevated cardiovascular risk: results of the IMPROVE trial. Kidney Int. 2007;72(7):879-885.
    • (2007) Kidney Int , vol.72 , Issue.7 , pp. 879-885
    • Bakris, G.L.1    Ruilope, L.2    Locatelli, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.