Depletion of glutathione does not affect electron transport chain complex activity in brain mitochondria: Implications for Parkinson disease and postmortem studies

Free Radical Biology and Medicine

Volumn 50, Issue 7, 2011, Pages 899-902

  Heales, Simon J R ^a   Menzes, Adrian ^a   Davey, Gavin P ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Antioxidant; Complex I; Electron transport chain; Free radicals; Glutathione; Mitochondria; Parkinson disease; Postmortem

Indexed keywords

BUTHIONINE SULFOXIMINE; CYTOCHROME C OXIDASE; GLUTATHIONE; MITOCHONDRIAL ENZYME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); UBIQUINOL CYTOCHROME C REDUCTASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPSY; BRAIN MITOCHONDRION; COMPLEX I DEFICIENCY; CONTROLLED STUDY; ELECTRON TRANSPORT; ENZYME ACTIVITY; GLUTATHIONE METABOLISM; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; RAT; RESPIRATORY CHAIN;

ANIMALS; ANIMALS, SUCKLING; BRAIN; BUTHIONINE SULFOXIMINE; CELLS, CULTURED; ELECTRON TRANSPORT; ELECTRON TRANSPORT COMPLEX I; ENZYME INHIBITORS; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; HUMANS; MALE; MITOCHONDRIA; OXIDATION-REDUCTION; PARKINSON DISEASE; POSTMORTEM CHANGES; RATS; RATS, WISTAR;

ANIMALIA; RATTUS;

EID: 79952042976     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2010.11.032     Document Type: Article

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