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Volumn 303, Issue 2, 2011, Pages 150-154

Ethyl pyruvate, an anti-inflammatory agent, inhibits tumor angiogenesis through inhibition of the NF-κB signaling pathway

Author keywords

Angiogenesis; Anti tumor; Ethyl pyruvate; NF B

Indexed keywords

ANGIOGENESIS INHIBITOR; ANTIINFLAMMATORY AGENT; ETHYLPYRUVATE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 79952039854     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2010.12.024     Document Type: Article
Times cited : (25)

References (21)
  • 1
    • 85013312416 scopus 로고
    • Tumor angiogenesis: therapeutic implications
    • Folkman J. Tumor angiogenesis: therapeutic implications. N. Engl. J. Med. 1971, 285:1182-1186.
    • (1971) N. Engl. J. Med. , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 2
    • 28244456279 scopus 로고    scopus 로고
    • Tumor inflammatory angiogenesis and its chemoprevention
    • Albini A., Tosetti F., Benelli R., Noonan D.M. Tumor inflammatory angiogenesis and its chemoprevention. Cancer Res. 2005, 65:100637-100641.
    • (2005) Cancer Res. , vol.65 , pp. 100637-100641
    • Albini, A.1    Tosetti, F.2    Benelli, R.3    Noonan, D.M.4
  • 5
    • 0037616308 scopus 로고    scopus 로고
    • Resuscitation with Ringer's ethyl pyruvate solution prolongs survival and modulates plasma cytokine and nitrite/nitrate concentrations in a rat model of lipopolysaccharide-induced shock
    • Venkataraman R., Kellum J.A., Song M., Fink M.P. Resuscitation with Ringer's ethyl pyruvate solution prolongs survival and modulates plasma cytokine and nitrite/nitrate concentrations in a rat model of lipopolysaccharide-induced shock. Shock 2002, 18:507-512.
    • (2002) Shock , vol.18 , pp. 507-512
    • Venkataraman, R.1    Kellum, J.A.2    Song, M.3    Fink, M.P.4
  • 6
    • 3142759947 scopus 로고    scopus 로고
    • Ethyl pyruvate ameliorates distant organ injury in a murine model of acute necrotizing pancreatitis
    • Yang R., Uchiyama T., Alber S.M., Han X., Watkins S.K., Delude R.L., Fink M.P. Ethyl pyruvate ameliorates distant organ injury in a murine model of acute necrotizing pancreatitis. Crit. Care Med. 2004, 32:1453-1459.
    • (2004) Crit. Care Med. , vol.32 , pp. 1453-1459
    • Yang, R.1    Uchiyama, T.2    Alber, S.M.3    Han, X.4    Watkins, S.K.5    Delude, R.L.6    Fink, M.P.7
  • 7
    • 36849053631 scopus 로고    scopus 로고
    • Effects of ethyl pyruvate on splenocyte proliferation and apoptosis in burn rats with delayed resuscitation
    • dong N., Yao Y.M., Dong Y.Q., Liu H., Wei P., Yu Y., Sheng Z.Y. Effects of ethyl pyruvate on splenocyte proliferation and apoptosis in burn rats with delayed resuscitation. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 2005, 17:393-396.
    • (2005) Zhongguo Wei Zhong Bing Ji Jiu Yi Xue , vol.17 , pp. 393-396
    • dong, N.1    Yao, Y.M.2    Dong, Y.Q.3    Liu, H.4    Wei, P.5    Yu, Y.6    Sheng, Z.Y.7
  • 8
    • 38449113261 scopus 로고    scopus 로고
    • Ethyl pyruvate, a potentially effective mitigator of damage after total-body irradiation
    • Epperly M., Jin S., Nie S., Cao S., Zhang X., Franicola D., Wang H., Fink M.P. Ethyl pyruvate, a potentially effective mitigator of damage after total-body irradiation. Radiat. Res. 2007, 168:552-559.
    • (2007) Radiat. Res. , vol.168 , pp. 552-559
    • Epperly, M.1    Jin, S.2    Nie, S.3    Cao, S.4    Zhang, X.5    Franicola, D.6    Wang, H.7    Fink, M.P.8
  • 10
    • 0344309146 scopus 로고    scopus 로고
    • Dose-dependent effects of ethyl pyruvate in mice subjected to mesenteric ischemia and reperfusion
    • Uchiyama T., Delude R.L., Fink M.P. Dose-dependent effects of ethyl pyruvate in mice subjected to mesenteric ischemia and reperfusion. Intens. Care Med. 2003, 29:2050-2058.
    • (2003) Intens. Care Med. , vol.29 , pp. 2050-2058
    • Uchiyama, T.1    Delude, R.L.2    Fink, M.P.3
  • 11
    • 14344255881 scopus 로고    scopus 로고
    • Ethyl pyruvate inhibits nuclear factor-cappaB-dependent signaling by directly targeting p65
    • Han Y., Englert J.A., Yang R., Delude R.L., Fink M.P. Ethyl pyruvate inhibits nuclear factor-cappaB-dependent signaling by directly targeting p65. J. Pharmacol. Exp. Ther. 2005, 312:1097-1105.
    • (2005) J. Pharmacol. Exp. Ther. , vol.312 , pp. 1097-1105
    • Han, Y.1    Englert, J.A.2    Yang, R.3    Delude, R.L.4    Fink, M.P.5
  • 13
    • 33847259309 scopus 로고    scopus 로고
    • The Akt inhibitor deguelin, is an angiopreventive agent also acting on the NF-kappaB pathway
    • Dell'Eva R., Ambrosini C., Minghelli S., Noonan D.M., Albini A., Ferrari N. The Akt inhibitor deguelin, is an angiopreventive agent also acting on the NF-kappaB pathway. Carcinogenesis 2007, 28:404-413.
    • (2007) Carcinogenesis , vol.28 , pp. 404-413
    • Dell'Eva, R.1    Ambrosini, C.2    Minghelli, S.3    Noonan, D.M.4    Albini, A.5    Ferrari, N.6
  • 14
    • 33947496370 scopus 로고    scopus 로고
    • Ethyl pyruvate: a novel anti-inflammatory agent
    • Fink M.P. Ethyl pyruvate: a novel anti-inflammatory agent. J. Intern. Med. 2007, 261:349-362.
    • (2007) J. Intern. Med. , vol.261 , pp. 349-362
    • Fink, M.P.1
  • 16
    • 77954033751 scopus 로고    scopus 로고
    • Ethyl pyruvate stabilizes hypoxia-inducible factor 1 alpha via stimulation of the TCA cycle
    • Kim S.Y., Choi J.S., Park C., Jeong J.W. Ethyl pyruvate stabilizes hypoxia-inducible factor 1 alpha via stimulation of the TCA cycle. Cancer Lett. 2010, 295:236-241.
    • (2010) Cancer Lett. , vol.295 , pp. 236-241
    • Kim, S.Y.1    Choi, J.S.2    Park, C.3    Jeong, J.W.4
  • 17
    • 0036136731 scopus 로고    scopus 로고
    • Angioprevention: angiogenesis is a common and key target for cancer chemopreventive agents
    • Tosetti F., Ferrari N., De Flora S., Albini A. Angioprevention: angiogenesis is a common and key target for cancer chemopreventive agents. FASEB J. 2002, 16:2-14.
    • (2002) FASEB J. , vol.16 , pp. 2-14
    • Tosetti, F.1    Ferrari, N.2    De Flora, S.3    Albini, A.4
  • 19
    • 7944223098 scopus 로고    scopus 로고
    • Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis
    • Sparmann A., Bar-Sagi D. Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis. Cancer Cell 2004, 6:447-458.
    • (2004) Cancer Cell , vol.6 , pp. 447-458
    • Sparmann, A.1    Bar-Sagi, D.2
  • 20
    • 24944587964 scopus 로고    scopus 로고
    • Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors
    • De Palma M., Venneri M.A., Galli R., Sergi Sergi L., Politi L.S., Sampaolesi M., Naldini L. Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors. Cancer Cell 2005, 8:211-216.
    • (2005) Cancer Cell , vol.8 , pp. 211-216
    • De Palma, M.1    Venneri, M.A.2    Galli, R.3    Sergi Sergi, L.4    Politi, L.S.5    Sampaolesi, M.6    Naldini, L.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.