Role of heat shock proteins in immune response and immunotherapy for human cancer

International Journal of Pharmaceutical Sciences Review and Research

Volumn 2, Issue 2, 2010, Pages 57-62

  Trivedi, Vandit ^a   Gadhvi, Pruthvi ^a   Chorawala, Mehul ^a   Shah, Gaurang ^a  

^a K B INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH   (India)

Author keywords

Cancer; Chaperone; Heat Shock Factor; Immune response

Indexed keywords

CANCER VACCINE; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 60; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90;

CANCER IMMUNOTHERAPY; COMPLEX FORMATION; HEAT SHOCK RESPONSE; HEAT STRESS; HEAT TOLERANCE; HUMAN; IMMUNE RESPONSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; REVIEW; SIGNAL TRANSDUCTION; UPREGULATION;

EID: 79952013014     PISSN: None     EISSN: 0976044X     Source Type: Journal    
DOI: None     Document Type: Review

References (55)

1. Ritossa F, A new puffing pattern induced by temperature shock and DNP in drosophila, Cellular and Molecular Life Sciences (CMLS), 18(12), 1962, 571-573.
2. Ritossa F, Discovery of the heat shock response, Cell Stress Chaperones, 1(2), 1996, 97-8.
3. Schlesinger MJ, Heat shock proteins, The Journal of Biological Chemistry, 265(21), 1990, 12111-12114.
4. Crevel G, Bates H, Huikeshoven H, Cotterill S, The Drosophila Dpit47 protein is a nuclear HSP90 cochaperone that interacts with DNA polymerase alpha., J. Cell. Sci., 114, 2001, June, 2015-25.
5. Kampinga, HH, Hageman, J, Vos, MJ, Kubota, H, Tanguay, RM, Bruford, EA, Guidelines for the nomenclature of the human heat shock proteins, Cell Stress and Chaperones, 14(1), 2009, 105-111.
6. Ciocca DR, Oesterrich S, Chamness GC, McGuire WL, and Fuqua SA, Biological and clinical implications of heat shock protein 27,000 (Hsp27): a review, J Natl Cancer Inst, 85(19), 1993, 1570-88.
7. Kim KK, Kim R, Kim S, Crystal structure of a small heat shock protein, Nature, 394, 1998, 595-9.
8. Van Montfort R, Slingsby C, Vierling E, Structure and function of the small heat shock protein/alphacrystallin family of molecular chaperones, Adv Protein Chem., 59, 2001, 105-56.
9. Sarto C, Binz PA, Mocarelli P, Heat shock proteins in human cancer, Electrophoresis, 21(6), 2000, 1218-26.
10. Arrigo AP, In search of the molecular mechanism by which small stress proteins counteract apoptosis during cellular differentiation, J Cell Biochem, 94(2), 2005, 241-6.
11. Gupta RS, Evolution of the chaperonin families (HSP60, HSP10 and Tcp-1) of proteins and the origin of eukaryotic cells, Mol. Microbiol, 15(1), 1995, 1-11.
12. Cappello F, de Macario EC, Marasa L, Zummo G, Macario AJ, HSP 60 expression, new locations, functions and perspectives for cancer diagnosis and therapy, Cancer Biol Ther, 7(6), 2008, 801-9.
13. Itoh H, Komatsuda A, Ohtani H, et al., Mammalian HSP60 is quickly sorted into the mitochondria under conditions of dehydration, Eur. J. Biochem, 269(23), 2002, 5931-8.
14. Ranford JC, Coates AR, Henderson B, Chaperonins are cell-signalling proteins: the unfolding biology of molecular chaperones, Expert Rev Mol Med, 2(8), 2000, 1-17.
15. Hansen JJ, Bross P, Westergaard M, et al., Genomic structure of the human mitochondrial chaperonin genes: HSP60 and HSP10 are localised head to head on chromosome 2 separated by a bidirectional promoter, Hum. Genet, 112 (1), 2003, 71-7.
16. Urushibara M, Kageyama Y, Akashi T, et al., HSP60 may predict good pathological response to neoadjuvant chemoradiotherapy in bladder cancer, Jpn. J. Clin. Oncol., 37(1), 2007, 56-61.
17. Cheng MY, Hartl FU, Horwich AL, The mitochondrial chaperonin HSP60 is required for its own assembly, Nature, 348, 1990, 455-8.
18. Fenton WA, Kashi Y, Furtak K, Horwich AL, Residues in chaperonin GroEL required for polypeptide binding and release, Nature, 371, 1994, 614-9.
19. Habich C, Burkart V, Heat shock protein 60: regulatory role on innate immune cells, Cell. Mol. Life Sci., 64(6), 2007, 742-51.
20. Koll H, Guiard B, Rassow J, et al., Antifolding activity of HSP60 couples protein import into the mitochondrial matrix with export to the intermembrane space, Cell, 68(6), 1992, 1163-75.
21. Tavaria M, Gabriele T, Kola I, Anderson RL, A hitchhiker's guide to the human HSP70 family, Cell Stress Chaperones, 1(1), 1996, 23-8.
22. Yoshimune K, Yoshimura T, Nakayama T, Nishino T, Esaki N, Hsc62, Hsc56, and GrpE, the third HSP70 chaperone system of Escherichia coli. Biochem. Biophys. Res. Commun., 293(5), 2002, 1389-95.
23. Ricaniadis N, Kataki A, Agnantis N, Androulakis G, Karakousis CP, Long-term prognostic significance of HSP-70, c-myc and HLA-DR expression in patients with malignant melanoma, Eur J Surg Oncol, 27 (1), 2001, 88-93.
24. Ramp U, Mahotka C, Heikaus S, Shibata T, Grimm MO, Willers R, Gabbert HE, Expression of heat shock protein 70 in renal cell carcinoma and its relation to tumor progression and prognosis, Histol. Histopathol. 22(10), 2007, 1099-107.
25. Heat shock proteins and cancer (Internet), Available from: http://www.healthvalue.net/HSP.html, Retrieved, 2009-05-26.
26. Panjwani N, Akbari O, Garcia S, Brazil M, Stockinger B, The HSC73 molecular chaperone: involvement in MHC class II antigen presentation, J Immunol, 163, 1999, 1936-1942.
27. Beere HM, Wolf BB, Cain K, Mosser DD, Mahboubi A, Kuwana T, Tailor P, Morimoto RI, Cohen GM, Green DR, Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome, Nat. Cell Biol., 2(8), 2000, 469-75.
28. Csermely P, Schnaider T, Soti C, Prohászka Z, Nardai G, The 90-kDa molecular chaperone family: structure, function, and clinical applications. A comprehensive review, Pharmacol. Ther., 79(2), 1998, 129-68.
29. Chen B, Zhong D, Monteiro A, Comparative genomics and evolution of the HSP90 family of genes across all kingdoms of organisms, BMC Genomics, 7, 2006, 156.
30. Kunisawa J, Shastri N, HSP90alpha chaperones large C-terminally extended proteolytic intermediates in the MHC class I antigen processing pathway, Immunity, 24, 2006, 523-534.
31. Grammatikakis N, Vultur A, Ramana CV, Siganou A, Schweinfest CW, Watson DK, Raptis L, The role of HSP90N, a new member of the HSP90 family, in signal transduction and neoplastic transformation,. J. Biol. Chem., 277 (10), 2002, 8312-20.
32. Pearl LH, Prodromou C, Structure and in vivo function of HSP90, Curr. Opin. Struct. Biol. 10 (1), 2000, 46-51
33. Prodromou C, Pearl LH, Structure and functional relationships of HSP90, Curr Cancer Drug Targets 3(5), 2003, 301-23.
34. Pearl LH, Prodromou C, Structure, function, and mechanism of the HSP90 molecular chaperone, Adv. Protein Chem., 59, 2001, 157-86.
35. Stebbins CE, Russo AA, Schneider C, Rosen N, Hartl FU, Pavletich NP, Crystal structure of an HSP90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent, Cell, 89 (2), 1997, 239-50.
36. Prodromou C, Roe SM, O'Brien R, Ladbury JE, Piper PW, Pearl LH, Identification and structural characterization of the ATP/ADP-binding site in the HSP90 molecular chaperone, Cell, 90 (1), 1997, 65-75.
37. Prodromou C, Roe SM, Piper PW, Pearl, A molecular clamp in the crystal structure of the Nterminal domain of the yeast HSP90 chaperone, Nat. Struct. Biol, 4 (6), 1997, 477-82.
38. Meyer P, Prodromou C, Hu B, Vaughan C, Roe SM, Panaretou B, Piper PW, Pearl LH, Structural and functional analysis of the middle segment of HSP90: implications for ATP hydrolysis and client protein and cochaperone interactions, Mol. Cell, 11 (3), 2003, 647-58.
39. Panaretou B, Siligardi G, Meyer P, Maloney A, Sullivan JK, Singh S, Millson SH, Clarke PA, Naaby-Hansen S, Stein R, Cramer R, Mollapour M, Workman P, Piper PW, Pearl LH, Prodromou C, Activation of the ATPase activity of HSP90 by the stress-regulated cochaperone aha1, Mol. Cell 10(6), 2002, 1307-18.
40. Buchner J, HSP90 & Co. - a holding for folding, Trends Biochem. Sci., 24 (4), 1999, 136-41.
41. Miyata Y, Yahara I, The 90-kDa heat shock protein, HSP90, binds and protects casein kinase II from self-aggregation and enhances its kinase activity, J. Biol. Chem., 267 (10), 1992, 7042-7.
42. Wiech H, Buchner J, Zimmermann R, Jakob U, HSP90 chaperones protein folding in vitro, Nature, 358 (6382), 1992, 169-70.
43. Jakob U, Lilie H, Meyer I, Buchner J, Transient interaction of HSP90 with early unfolding intermediates of citrate synthase. Implications for heat shock in vivo, J. Biol. Chem., 270 (13), 1995, 7288-94.
44. Fontana J, Fulton D, Chen Y, Fairchild TA, McCabe TJ, Fujita N, Tsuruo T, Sessa WC, Domain mapping studies reveal that the M domain of HSP90 serves as a molecular scaffold to regulate Akt-dependent phosphorylation of endothelial nitric oxide synthase and NO release, Circ. Res. 90 (8), 2002, 866-73.
45. Calderwood SK, Khaleque MA, Sawyer DB, Ciocca DR, Heat shock proteins in cancer: chaperones of tumorigenesis, Trends Biochem. Sci., 31(3), 2006, 164-72.
46. Eustace BK, Sakurai T, Stewart JK, Yimlamai D, Unger C, Zehetmeier C, Lain B, Torella C, Henning SW, Beste G, Scroggins BT, Neckers L, Ilag LL, Jay DG, Functional proteomic screens reveal an essential extracellular role for HSP90 alpha in cancer cell invasiveness, Nat. Cell Biol., 6(6), 2004, 507-14.
47. Whitesell L, Lindquist SL, HSP90 and the chaperoning of cancer, Nat. Rev. Cancer, 5(10), 2005, 761-72.
48. Sato S, Fujita N, Tsuruo T, Modulation of Akt kinase activity by binding to HSP90, Proc. Natl. Acad. Sci. U.S.A., 97 (20), 2000, 10832-7.
49. Febbario MA, Ott P, Nielsen HB, Steensberg A, Keller C, Krustrup P, Secher NH, and Pedersen BK, Exercise induces hepatosplanchnic release of heat shock protein 72 in humans, J. Physiol, 544, 2002, 957-962.
50. Guzhova I, Kislyakova K, Moskaliova O, Fridlanskaya I, Tytell M, Cheetham M, Margulis B, In vitro studies show that Hsp70 can be released by glia and that exogenous Hsp70 can enhance neuronal stress tolerance, Brain Res 914, 2001, 66-73.
51. Walsh RC, Koukoulas I, Granham Moseley PL, Hargreaves M, and Febbraio MA, Exercise increases serum Hsp72 in humans, Cell stress Chaperones 6, 2001, 386-392.
52. Hightower LE and Guidon PT, Selective release from cultured mammalian cells of heat-shock (stress) proteins that resemble glia-axon transfer proteins, J Cell Physiol, 138, 1989, 257-266.
53. Bruce Goldman, Heat Shock Proteins Vaccine Potential: From basic science breakthroughs to feasible personalized medicine, 2002, 2
54. Srivastava PK, Udono H, Blachere NE, Li Z, Heat shock proteins transfer peptides during antigen processing and CTL priming, Immunogenetics, 39, 1994, 93-98.
55. Basu S, Srivastava PK, Fever-like temperature induces maturation of dendritic cells through induction of HSP90, Int Immunol, 15, 2003, 1053-1061.