Altered profile and D2-dopamine receptor modulation of high voltage-activated calcium current in striatal medium spiny neurons from animal models of Parkinson's disease

Neuroscience

Volumn 177, Issue , 2011, Pages 240-251

  Martella, G ^a   Madeo, G ^a   Schirinzi, T ^a   Tassone, A ^b   Sciamanna, G ^b   Spadoni, F ^a   Stefani, A ^a   Shen, J ^c   Pisani, A ^a,b   Bonsi, P ^b  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

6 hydroxydopamine; DJ 1; HVA calcium channels; Medium spiny neuron; PINK1; Reserpine

Indexed keywords

CALCIUM CHANNEL L TYPE; CALCIUM CHANNEL N TYPE; CALCIUM CHANNEL P TYPE; DJ 1 PROTEIN; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE RECEPTOR STIMULATING AGENT; NIFEDIPINE; OMEGA CONOTOXIN GVIA; OXIDOPAMINE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE INDUCED KINASE 1; PROTEIN KINASE; QUINPIROLE; RESERPINE; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; CELL ISOLATION; CHANNEL GATING; CONTROLLED STUDY; DISEASE MODEL; GENE DELETION; MEDIUM SPINY NERVE CELL; MOUSE; NERVE CELL; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION; STRIATE CORTEX;

ANIMALS; CALCIUM CHANNELS; CALCIUM CHANNELS, L-TYPE; DISEASE MODELS, ANIMAL; DOPAMINE; MALE; MICE; MICE, KNOCKOUT; NEOSTRIATUM; NEURONS; ONCOGENE PROTEINS; ORGAN CULTURE TECHNIQUES; PARKINSONIAN DISORDERS; RATS; RATS, WISTAR; RECEPTORS, DOPAMINE D2;

EID: 79952006735     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2010.12.057     Document Type: Article

References (51)

1. Arias-Montaño J.A., Floran B., Floran L., Aceves J., Young J.M. Dopamine d(1) receptor facilitation of depolarization-induced release of gamma-amino-butyric acid in rat striatum is mediated by the cAMP/PKA pathway and involves P/Q-type calcium channels. Synapse 2007, 61:310-319.
2. Baunez C., Nieoullon A., Amalric M. In a rat model of parkinsonism, lesions of the subthalamic nucleus reverse increases of reaction time but induce a dramatic premature responding deficit. J Neurosci 1995, 15:6531-6541.
3. Bennett B.D., Wilson C.J. Synaptic regulation of action potential timing in neostriatal cholinergic interneurons. J Neurosci 1998, 18:8539-8549.
4. Bennett B.D., Wilson C.J. Spontaneous activity of neostriatal cholinergic interneurons in vitro. J Neurosci 1999, 19:5586-5596.
5. Bezard E., Gross C.E. Compensatory mechanisms in experimental and human parkinsonism: towards a dynamic approach. Prog Neurobiol 1998, 55:93-116.
6. Blandini F., Nappi G., Tassorelli C., Martignoni E. Functional changes of the basal ganglia circuitry in Parkinson's disease. Prog Neurobiol 2000, 62:63-88.
7. Bolam J.P., Ingham C.A., Izzo P.N., Levey A.I., Rye D.B., Smith A.D., Wainer B.H. Substance P-containing terminals in synaptic contact with cholinergic neurons in the neostriatum and basal forebrain: a double immunocytochemical study in the rat. Brain Res 1986, 397:279-289.
8. Bonifati V., Rizzu P., Squitieri F., Krieger E., Vanacore N., van Swieten J.C., Brice A., van Duijn C.M., Oostra B., Meco G., Heutink P. DJ-1(PARK7), a novel gene for autosomal recessive, early onset parkinsonism. Neurol Sci 2003, 24:159-160.
9. Bonsi P., Cuomo D., Martella G., Sciamanna G., Tolu M., Calabresi P., Bernardi G., Pisani A. Mitochondrial toxins in Basal Ganglia disorders: from animal models to therapeutic strategies. Curr Neuropharmacol 2006, 4:69-75.
10. Bonsi P., Pisani A., Bernardi G., Calabresi P. Stimulus frequency, calcium levels and striatal synaptic plasticity. Neuroreport 2003, 14:419-422.
11. Butkerait P., Wang H.Y., Friedman E. Increases in guanine nucleotide binding to striatal G proteins is associated with dopamine receptor supersensitivity. J Pharmacol Exp Ther 1994, 271:422-428.
12. Cabrera-Vera T.M., Hernandez S., Earls L.R., Medkova M., Sundgren-Andersson A.K., Surmeier D.J., Hamm H.E. RGS9-2 modulates D2 dopamine receptor-mediated Ca2+ channel inhibition in rat striatal cholinergic interneurons. Proc Natl Acad Sci U S A 2004, 101:16339-16344.
13. Calabresi P., Maj R., Pisani A., Mercuri N.B., Bernardi G. Long-term synaptic depression in the striatum: physiological and pharmacological characterization. J Neurosci 1992, 12:4224-4233.
14. Calabresi P., Picconi B., Tozzi A., Di Filippo M. Dopamine-mediated regulation of corticostriatal synaptic plasticity. Trends Neurosci 2007, 30:211-219.
15. Chan C.S., Gertler T.S., Surmeier D.J. Calcium homeostasis, selective vulnerability and Parkinson's disease. Trends Neurosci 2009, 32:249-256.
16. Dawson T.M., Ko H.S., Dawson V.L. Genetic animal models of Parkinson's disease. Neuron 2010, 66:646-661.
17. Day M., Wang Z., Ding J., An X., Ingham C.A., Shering A.F., Wokosin D., Ilijic E., Sun Z., Sampson A.R., Mugnaini E., Deutch A.Y., Sesack S.R., Arbuthnott G.W., Surmeier D.J. Selective elimination of glutamatergic synapses on striatopallidal neurons in Parkinson disease models. Nat Neurosci 2006, 9:251-259.
18. Deutch A.Y., Colbran R.J., Winder D.J. Striatal plasticity and medium spiny neuron dendritic remodeling in Parkinsonism. Parkinsonism Relat Disord 2007, 13(Suppl 3):S251-S258.
19. Fass D.M., Takimoto K., Mains R.E., Levitan E.S. Tonic dopamine inhibition of L-type Ca2+ channel activity reduces alpha1D Ca2+ channel gene expression. J Neurosci 1999, 19:3345-3352.
20. Fuentes R., Petersson P., Siesser W.B., Caron M.G., Nicolelis M.A. Spinal cord stimulation restores locomotion in animal models of Parkinson's disease. Science 2009, 323:1578-1582.
21. Galati S., Stanzione P., D'Angelo V., Fedele E., Marzetti F., Sancesario G., Procopio T., Stefani A. The pharmacological blockade of medial forebrain bundle induces an acute pathological synchronization of the cortico-subthalamic nucleus-globus pallidus pathway. J Physiol 2009, 587:4405-4423.
22. Goldberg M.S., Pisani A., Haburcak M., Vortherms T.A., Kitada T., Costa C., Tong Y., Martella G., Tscherter A., Martins A., Bernardi G., Roth B.L., Pothos E.N., Calabresi P., Shen J. Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-1. Neuron 2005, 45:489-496.
23. Gubellini P., Picconi B., Di Filippo M., Calabresi P. Downstream mechanisms triggered by mitochondrial dysfunction in the basal ganglia: from experimental models to neurodegenerative diseases. Biochim Biophys Acta 2010, 1802:151-161.
24. Hao L.-Y., Glasson B.I., Bonini N.M. DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function. Proc Natl Acad Sci U S A 2010, 107:9747-9752.
25. Harrison M.B., Kumar S., Hubbard C.A., Trugman J.M. Early changes in neuropeptide mRNA expression in the striatum following reserpine treatment. Exp Neurol 2001, 167:321-328.
26. Hernandez-Lopez S., Tkatch T., Perez-Garci E., Galarraga E., Bargas J., Hamm H., Surmeier D.J. D2 dopamine receptors in striatal medium spiny neurons reduce L-type Ca2+ currents and excitability via a novel PLCβ1-IP3-calcineurin-signaling cascade. J Neurosci 2000, 20:8987-8995.
27. Kisilevsky A.E., Zamponi G.W. D2 dopamine receptors interact directly with N-type calcium channels and regulate channel surface expression levels. Channels (Austin) 2008, 2:269-277.
28. Kitada T., Pisani A., Porter D.R., Yamaguchi H., Tscherter A., Martella G., Bonsi P., Zhang C., Pothos E.N., Shen J. Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice. Proc Natl Acad Sci U S A 2007, 104:11441-11446.
29. Kreitzer A.C., Malenka R.C. Endocannabinoid-mediated rescue of striatal LTD and motor deficits in Parkinson's disease models. Nature 2007, 445:643-647.
30. LaHoste G.J., Marshall J.F. New concepts in dopamine receptor plasticity. Ann N Y Acad Sci 1993, 702:183-196.
31. Martella G., Spadoni F., Sciamanna G., Tassone A., Bernardi G., Pisani A., Bonsi P. Age-related functional changes of high-voltage-activated calcium channels in different neuronal subtypes of mouse striatum. Neuroscience 2008, 152:469-476.
32. Meredith G.E., Totterdell S., Potashkin J.A., Surmeier D.J. Modeling PD pathogenesis in mice: advantages of a chronic MPTP protocol. Parkinsonism Relat Disord 2008, 14(Suppl 2):S112-S115.
33. Momiyama T., Koga E. Dopamine d(2)-like receptors selectively block N-type Ca(2+) channels to reduce GABA release onto rat striatal cholinergic interneurones. J Physiol 2001, 533:479-492.
34. Olson P.A., Tkatch T., Hernandez-Lopez S., Ulrich S., Ilijic E., Mugnaini E., Zhang H., Bezprozvanny I., Surmeier D.J. G-protein-coupled receptor modulation of striatal CaV13 L-type Ca2+ channels is dependent on a Shank-binding domain. J Neurosci 2005, 25:1050-1062.
35. Pietrobon D. CaV21 channelopathies. Pflugers Arch 2010, 460:375-393.
36. Pisani A., Bonsi P., Centonze D., Calabresi P., Bernardi G. Activation of D2-like dopamine receptors reduces synaptic inputs to striatal cholinergic interneurons. J Neurosci 2000, 20:RC69.
37. Pisani A., Centonze D., Bernardi G., Calabresi P. Striatal synaptic plasticity: implications for motor learning and Parkinson's disease. Mov Disord 2005, 20:395-402.
38. Pisani A., Martella G., Tscherter A., Bonsi P., Sharma N., Bernardi G., Standaert D.G. Altered responses to dopaminergic D2 receptor activation and N-type calcium currents in striatal cholinergic interneurons in a mouse model of DYT1 dystonia. Neurobiol Dis 2006, 24:318-325.
39. Prieto G.A., Perez-Burgos A., Fiordelisio T., Salgado H., Galarraga E., Drucker-Colin R., Bargas J. Dopamine d(2)-class receptor supersensitivity as reflected in Ca2+ current modulation in neostriatal neurons. Neuroscience 2009, 164:345-350.
40. Radja F., el Mansari M., Soghomonian J.J., Dewar K.M., Ferron A., Reader T.A., Descarries L. Changes of D1 and D2 receptors in adult rat neostriatum after neonatal dopamine denervation: quantitative data from ligand binding, in situ hybridization and iontophoresis. Neuroscience 1993, 57:635-648.
41. Rodnitzky R.L. Can calcium antagonists provide a neuroprotective effect in Parkinson's disease?. Drugs 1999, 57:845-849.
42. Rubinstein M., Muschietti J.P., Gershanik O., Flawia M.M., Stefano F.J. Adaptive mechanisms of striatal D1 and D2 dopamine receptors in response to a prolonged reserpine treatment in mice. J Pharmacol Exp Ther 1990, 252:810-816.
43. Salgado H., Tecuapetla F., Perez-Rosello T., Perez-Burgos A., Perez-Garci E., Galarraga E., Bargas J. A reconfiguration of CaV2 Ca2+ channel current and its dopaminergic D2 modulation in developing neostriatal neurons. J Neurophysiol 2005, 94:3771-3787.
44. Schuster S., Doudnikoff E., Rylander D., Berthet A., Aubert I., Ittrich C., Bloch B., Cenci M.A., Surmeier D.J., Hengerer B., Bezard E. Antagonizing L-type Ca2+ channel reduces development of abnormal involuntary movement in the rat model of L-3,4-dihydroxyphenylalanine-induced dyskinesia. Biol Psychiatry 2009, 65:518-526.
45. Smith Y., Villalba R. Striatal and extrastriatal dopamine in the basal ganglia: an overview of its anatomical organization in normal and Parkinsonian brains. Mov Disord 2008, 23(Suppl 3):S534-S547.
46. Spadoni F., Martella G., Martorana A., Lavaroni F., D'Angelo V., Bernardi G., Stefani A. Opioid-mediated modulation of calcium currents in striatal and pallidal neurons following reserpine treatment: focus on kappa response. Synapse 2004, 51:194-205.
47. Surmeier D.J., Bargas J., Hemmings H.C., Nairn A.C., Greengard P. Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons. Neuron 1995, 14:385-397.
48. Surmeier D.J., Guzman J.N., Sanchez-Padilla J. Calcium, cellular aging, and selective neuronal vulnerability in Parkinson's disease. Cell Calcium 2010, 47:175-182.
49. Valente E.M., Salvi S., Ialongo T., Marongiu R., Elia A.E., Caputo V., Romito L., Albanese A., Dallapiccola B., Bentivoglio A.R. PINK1 mutations are associated with sporadic early-onset Parkinsonism. Ann Neurol 2004, 56:336-341.
50. Yan Z., Song W.J., Surmeier J. D2 dopamine receptors reduce N-type Ca2+ currents in rat neostriatal cholinergic interneurons through a membrane-delimited, protein-kinase-C-insensitive pathway. J Neurophysiol 1997, 77:1003-1015.
51. Zhen X., Torres C., Cai G., Friedman E. Inhibition of protein tyrosine/mitogen-activated protein kinase phosphatase activity is associated with D2 dopamine receptor supersensitivity in a rat model of Parkinson's disease. Mol Pharmacol 2002, 62:1356-1363.