The carriage of the type 1 diabetes-associated R262W variant of human LNK correlates with increased proliferation of peripheral blood monocytes in diabetic patients

Pediatric Diabetes

Volumn 12, Issue 2, 2011, Pages 127-132

  Lavrikova, Elena Y ^a   Nikitin, Alexey G ^a   Kuraeva, Tamara L ^b   Peterkova, Valentina A ^b   Tsitlidze, Nina M ^c   Chistiakov, Dimitry A ^a   Nosikov, Valery V ^a  

^a STATE RESEARCH INSTITUTE OF GENETICS AND SELECTION OF INDUSTRIAL MICROORGANISMS   (Russian Federation)

^b N N BLOKHIN NATIONAL MEDICAL RESEARCH CENTER OF ONCOLOGY   (Russian Federation)

^c Russian Academy for Advanced Medical Studies   (Russian Federation)

Author keywords

Association; Human LNK type 1 diabetes; Proliferation of T cells; SH2B3 R262W

Indexed keywords

ADAPTOR PROTEIN; ANTIBODY; CD28 ANTIBODY; CD3 ANTIBODY; DNA; LYMPHOCYTE ADAPTOR PROTEIN; UNCLASSIFIED DRUG;

ADULT; ALLELE; ARTICLE; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; DIABETIC PATIENT; DNA SYNTHESIS; FEMALE; GENETIC PREDISPOSITION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HUMAN; HUMAN CELL; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTE PROLIFERATION; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; RUSSIAN FEDERATION; T LYMPHOCYTE;

ADOLESCENT; ADULT; AMINO ACID SUBSTITUTION; ARGININE; BLOOD CELL COUNT; CASE-CONTROL STUDIES; CELL PROLIFERATION; CHILD; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS, TYPE 1; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HETEROZYGOTE; HUMANS; MALE; MONOCYTES; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEINS; TRYPTOPHAN; UP-REGULATION; YOUNG ADULT;

EID: 79951998354     PISSN: 1399543X     EISSN: 13995448     Source Type: Journal    
DOI: 10.1111/j.1399-5448.2010.00656.x     Document Type: Article

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