-
1
-
-
40949095655
-
Guide to Receptors and Channels (GRAC)
-
3rd edn.
-
Alexander SPH, Mathie A, Peters JA, (2008). Guide to Receptors and Channels (GRAC). 3rd edn. Br J Pharmacol 153 (Suppl. 2): S1-S209.
-
(2008)
Br J Pharmacol
, vol.153
, Issue.2 SUPPL.
-
-
Alexander, S.P.H.1
Mathie, A.2
Peters, J.A.3
-
2
-
-
62649095692
-
Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR
-
Al-Nedawi K, Meehan B, Kerbel RS, Allison AC, Rak J, (2009). Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR. Proc Natl Acad Sci U S A 106: 3794-3799.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 3794-3799
-
-
Al-Nedawi, K.1
Meehan, B.2
Kerbel, R.S.3
Allison, A.C.4
Rak, J.5
-
3
-
-
33644546368
-
Tumor endothelial cells express epidermal growth factor receptor (EGFR) but not ErbB3 and are responsive to EGF and to EGFR kinase inhibitors
-
Amin DN, Hida K, Bielenberg DR, Klagsbrun M, (2006). Tumor endothelial cells express epidermal growth factor receptor (EGFR) but not ErbB3 and are responsive to EGF and to EGFR kinase inhibitors. Cancer Res 66: 2173-2180.
-
(2006)
Cancer Res
, vol.66
, pp. 2173-2180
-
-
Amin, D.N.1
Hida, K.2
Bielenberg, D.R.3
Klagsbrun, M.4
-
4
-
-
0032524336
-
Potato carboxypeptidase inhibitor, a T-knot protein, is an epidermal growth factor antagonist that inhibits tumor cell growth
-
DOI 10.1074/jbc.273.20.12370
-
Blanco-Aparicio C, Molina MA, Fernandez-Salas E, Frazier ML, Mas JM, Querol E, et al. (1998). Potato carboxypeptidase inhibitor, a T-knot protein, is an epidermal growth factor antagonist that inhibits tumor cell growth. J Biol Chem 273: 12370-12377. (Pubitemid 28240606)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.20
, pp. 12370-12377
-
-
Blanco-Aparicio, C.1
Molina, M.A.2
Fernandez-Salas, E.3
Frazier, M.L.4
Mas, J.M.5
Querol, E.6
Aviles, F.X.7
De Llorens, R.8
-
5
-
-
11244261160
-
ADAMs: Key components in egfr signalling and development
-
DOI 10.1038/nrm1548
-
Blobel CP, (2005). Adams: key components in EGFR signalling and development. Nat Rev Mol Cell Biol 6: 32-43. (Pubitemid 40064897)
-
(2005)
Nature Reviews Molecular Cell Biology
, vol.6
, Issue.1
, pp. 32-43
-
-
Blobel, C.P.1
-
6
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities 434 utilizing the principle of protein-dye binding
-
Bradford MM, (1976). A rapid and sensitive method for the quantitation of microgram quantities 434 utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254.
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
7
-
-
0344443730
-
Azide-Alkyne Coupling: A Powerful Reaction for Bioconjugate Chemistry
-
DOI 10.1002/cbic.200300705
-
Breinbauer R, Kóhn M, (2003). Azide-alkyne coupling: a powerful reaction for bioconjugate chemistry. Chembiochem 4: 1147-1149. (Pubitemid 37462815)
-
(2003)
ChemBioChem
, vol.4
, Issue.11
, pp. 1147-1149
-
-
Breinbauer, R.1
Kohn, M.2
-
8
-
-
33846675306
-
Combinations of tomato and broccoli enhance antitumor activity in dunning R3327-H prostate adenocarcinomas
-
DOI 10.1158/0008-5472.CAN-06-3462
-
Canene-Adams K, Lindshield BL, Wang S, Jeffery EH, Clinton SK, Erdman JW Jr, (2007). Combinations of tomato and broccoli enhance antitumor activity in dunning r3327-h prostate adenocarcinomas. Cancer Res 67: 836-843. (Pubitemid 46192225)
-
(2007)
Cancer Research
, vol.67
, Issue.2
, pp. 836-843
-
-
Canene-Adams, K.1
Lindshield, B.L.2
Wang, S.3
Jeffery, E.H.4
Clinton, S.K.5
Erdman Jr., J.W.6
-
9
-
-
33846682753
-
Polymyxin B as inhibitor of LPS contamination of Schistosoma mansoni recombinant proteins in human cytokine analysis
-
Cardoso LS, Araujo MI, Goes AM, Pacifico LG, Oliveira RR, Oliveira SC, (2007). Polymyxin B as inhibitor of LPS contamination of Schistosoma mansoni recombinant proteins in human cytokine analysis. Microb Cell Fact 6: 1.
-
(2007)
Microb Cell Fact
, vol.6
, pp. 1
-
-
Cardoso, L.S.1
Araujo, M.I.2
Goes, A.M.3
Pacifico, L.G.4
Oliveira, R.R.5
Oliveira, S.C.6
-
10
-
-
30744479430
-
Angiogenesis in life, disease and medicine
-
DOI 10.1038/nature04478, PII NATURE04478
-
Carmeliet P, (2005). Angiogenesis in life, disease and medicine. Nature 438: 932-936. (Pubitemid 43093958)
-
(2005)
Nature
, vol.438
, Issue.7070
, pp. 932-936
-
-
Carmeliet, P.1
-
11
-
-
0034793341
-
Plant cyclotides: Circular, knotted peptide toxins
-
DOI 10.1016/S0041-0101(01)00129-5, PII S0041010101001295
-
Craik DJ, (2001). Plant cyclotides: circular, knotted peptide toxins. Toxicon 39: 1809-1813. (Pubitemid 32971818)
-
(2001)
Toxicon
, vol.39
, Issue.12
, pp. 1809-1813
-
-
Craik, D.J.1
-
12
-
-
3242793256
-
Isolation and characterization of wound-inducible carboxypeptidase inhibitor from tomato leaves
-
DOI 10.1016/j.phytochem.2004.06.007, PII S0031942204002560
-
Diez-Diaz M, Conejero V, Rodrigo I, Pearce G, Ryan CA, (2004). Isolation and characterization of wound-inducible carboxypeptidase inhibitor from tomato leaves. Phytochemistry 65: 1919-1924. (Pubitemid 38981681)
-
(2004)
Phytochemistry
, vol.65
, Issue.13
, pp. 1919-1924
-
-
Diez-Diaz, M.1
Conejero, V.2
Rodrigo, I.3
Pearce, G.4
Ryan, C.A.5
-
13
-
-
2442715458
-
The role of tomato products and lycopene in the prevention of prostate cancer: A meta-analysis of observational studies
-
Etminan M, Takkouche B, Caamano-Isorna F, (2004). The role of tomato products and lycopene in the prevention of prostate cancer: a meta-analysis of observational studies. Cancer Epidemiol Biomarkers Prev 13: 340-345. (Pubitemid 38737456)
-
(2004)
Cancer Epidemiology Biomarkers and Prevention
, vol.13
, Issue.3
, pp. 340-345
-
-
Etminan, M.1
Takkouche, B.2
Caamano-Isorna, F.3
-
14
-
-
0028929803
-
Angiogenesis in cancer, vascular, rheumatoid and other disease
-
Folkman J, (1995). Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1: 27-31.
-
(1995)
Nat Med
, vol.1
, pp. 27-31
-
-
Folkman, J.1
-
15
-
-
0035910614
-
2 receptors differentially regulate angiopoietin-2 and vascular endothelial growth factor expression and angiogenesis by modulating heparin binding-epidermal growth factor (EGF)-mediated EGF receptor transactivation
-
Fujiyama S, Matsubara H, Nozawa Y, Maruyama K, Mori Y, Tsutsumi Y, et al. (2001). Angiotensin AT(1) and AT(2) receptors differentially regulate angiopoietin-2 and vascular endothelial growth factor expression and angiogenesis by modulating heparin binding-epidermal growth factor (EGF)-mediated EGF receptor transactivation. Circ Res 88: 22-29. (Pubitemid 32064078)
-
(2001)
Circulation Research
, vol.88
, Issue.1
, pp. 22-29
-
-
Fujiyama, S.1
Matsubara, H.2
Nozawa, Y.3
Maruyama, K.4
Mori, Y.5
Tsutsumi, Y.6
Masaki, H.7
Uchiyama, Y.8
Koyama, Y.9
Nose, A.10
Iba, O.11
Tateishi, E.12
Ogata, N.13
Jyo, N.14
Higashiyama, S.15
Iwasaka, T.16
-
16
-
-
0034655749
-
Protein-tyrosine-phosphatase-mediated epidermal growth factor (EGF) receptor transinactivation and EGF receptor-independent stimulation of mitogen-activated protein kinase by bradykinin in A431 cells
-
DOI 10.1042/0264-6021:3470441
-
Graness A, Hanke S, Boehmer FD, Presek P, Liebmann C, (2000). Protein-tyrosine-phosphatase-mediated epidermal growth factor (EGF) receptor transinactivation and EGF receptor-independent stimulation of mitogen-activated protein kinase by bradykinin in A431 cells. Biochem J 347: 441-447. (Pubitemid 30229391)
-
(2000)
Biochemical Journal
, vol.347
, Issue.2
, pp. 441-447
-
-
Graness, A.1
Hanke, S.2
Boehmer, F.D.3
Presek, P.4
Liebmann, C.5
-
18
-
-
0010374065
-
Distribution of carboxypeptidase isoinhibitors in the potato plant
-
Hass GM, Derr JE, (1979). Distribution of carboxypeptidase isoinhibitors in the potato plant. Plant Physiol 64: 1029-1031.
-
(1979)
Plant Physiol
, vol.64
, pp. 1029-1031
-
-
Hass, G.M.1
Derr, J.E.2
-
19
-
-
0019879637
-
Amino acid sequence of a carboxypeptidase inhibitor from tomato fruit
-
Hass GM, Hermodson MA, (1981). Amino acid sequence of a carboxypeptidase inhibitor from tomato fruit. Biochemistry 20: 2256-2260.
-
(1981)
Biochemistry
, vol.20
, pp. 2256-2260
-
-
Hass, G.M.1
Hermodson, M.A.2
-
20
-
-
0019336877
-
Cleavage of the carboxypeptidase inhibitor from potatoes by carboxypeptidase A
-
Hass GM, Ryan CA, (1980). Cleavage of the carboxypeptidase inhibitor from potatoes by carboxypeptidase A. Biochem Biophys Res Commun 97: 1481-1486.
-
(1980)
Biochem Biophys Res Commun
, vol.97
, pp. 1481-1486
-
-
Hass, G.M.1
Ryan, C.A.2
-
21
-
-
20644435471
-
Carboxypeptidase inhibitor from potatoes
-
L. Lorand (ed.). Academic Press: New York
-
Hass GM, Ryan CA, (1982). Carboxypeptidase inhibitor from potatoes. In:, L. Lorand, (ed.). Methods in Enzymology, Proteolytic Enzymes Part C, 3rd edn., Vol. 80. Academic Press: New York, pp. 778-791.
-
(1982)
Methods in Enzymology, Proteolytic Enzymes Part C, 3rd Edn., Vol. 80
, pp. 778-791
-
-
Hass, G.M.1
Ryan, C.A.2
-
22
-
-
0041631044
-
Potential role for ADAM15 in pathological neovascularization in mice
-
DOI 10.1128/MCB.23.16.5614-5624.2003
-
Horiuchi K, Weskamp G, Lum L, Hammes HP, Cai H, Brodie TA, et al. (2003). Potential role for ADAM15 in pathological neovascularization in mice. Mol Cell Biol 23: 5614-5624. (Pubitemid 36951327)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.16
, pp. 5614-5624
-
-
Horiuchi, K.1
Weskamp, G.2
Lum, L.3
Hammes, H.-P.4
Cai, H.5
Brodie, T.A.6
Ludwig, T.7
Chiusaroli, R.8
Baron, R.9
Preissner, K.T.10
Manova, K.11
Blobel, C.P.12
-
23
-
-
33751566963
-
Differential effects of matrix and growth factors on endothelial and fibroblast motility: Application of a modified cell migration assay
-
DOI 10.1002/jcb.20994
-
van Horssen R, Galjart N, Rens JA, Eggermont AM, ten Hagen TL, (2006). Differential effects of matrix and growth factors on endothelial and fibroblast motility: application of a modified cell migration assay. J Cell Biochem 99: 1536-1552. (Pubitemid 44845714)
-
(2006)
Journal of Cellular Biochemistry
, vol.99
, Issue.6
, pp. 1536-1552
-
-
Van Horssen, R.1
Galjart, N.2
Rens, J.A.P.3
Eggermont, A.M.M.4
Ten Hagen, T.L.M.5
-
24
-
-
0038262034
-
Can the consumption of tomatoes or lycopene reduce cancer risk?
-
Hwang ES, Bowen PE, (2002). Can the consumption of tomatoes or lycopene reduce cancer risk? Integr Cancer Ther 1: 121-132.
-
(2002)
Integr Cancer Ther
, vol.1
, pp. 121-132
-
-
Hwang, E.S.1
Bowen, P.E.2
-
25
-
-
33751073415
-
A novel suite of cyclotides from Viola odorata: Sequence variation and the implications for structure, function and stability
-
DOI 10.1042/BJ20060627
-
Ireland DC, Colgrave ML, Craik DJ, (2006). A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability. Biochemical J 400: 1-12. (Pubitemid 44763814)
-
(2006)
Biochemical Journal
, vol.400
, Issue.1
, pp. 1-12
-
-
Ireland, D.C.1
Colgrave, M.L.2
Craik, D.J.3
-
26
-
-
33845610113
-
Grafting of thrombopoietin-mimetic peptides into cystine knot miniproteins yields high-affinity thrombopoietin antagonists and agonists
-
DOI 10.1111/j.1742-4658.2006.05567.x
-
Krause S, Schmoldt HU, Wentzel A, Ballmaier M, Friedrich K, Kolmar H, (2007). Grafting of thrombopoietin-mimetic peptides into cystine knot miniproteins yields high-affinity thrombopoietin antagonists and agonists. FEBS J 274: 86-95. (Pubitemid 44952900)
-
(2007)
FEBS Journal
, vol.274
, Issue.1
, pp. 86-95
-
-
Krause, S.1
Schmoldt, H.-U.2
Wentzel, A.3
Ballmaier, M.4
Friedrich, K.5
Kolmar, H.6
-
27
-
-
0025771125
-
Regulation of metallocarboxypeptidase inhibitor gene-expression in tomato
-
Martineau B, McBride KE, Houck CM, (1991). Regulation of metallocarboxypeptidase inhibitor gene-expression in tomato. Mol Gen Genet 228: 281-286.
-
(1991)
Mol Gen Genet
, vol.228
, pp. 281-286
-
-
Martineau, B.1
McBride, K.E.2
Houck, C.M.3
-
29
-
-
37548999751
-
HB-EGF promotes angiogenesis in endothelial cells via PI3-kinase and MAPK signalling pathways
-
Mehta VB, Besner GE, (2007). HB-EGF promotes angiogenesis in endothelial cells via PI3-kinase and MAPK signalling pathways. Growth Factors 25: 253-263.
-
(2007)
Growth Factors
, vol.25
, pp. 253-263
-
-
Mehta, V.B.1
Besner, G.E.2
-
30
-
-
0037387681
-
Cytochrome P450 2C9-derived epoxyeicosatrienoic acids induce angiogenesis via cross-talk with the epidermal growth factor receptor
-
Michaelis UR, Fisslthaler B, Medhora M, Harder D, Fleming I, Busse R, (2003). Cytochrome P450 2C9-derived epoxyeicosatrienoic acids induce angiogenesis via cross-talk with the epidermal growth factor receptor. FASEB J 17: 770-772.
-
(2003)
FASEB J
, vol.17
, pp. 770-772
-
-
Michaelis, U.R.1
Fisslthaler, B.2
Medhora, M.3
Harder, D.4
Fleming, I.5
Busse, R.6
-
31
-
-
0034926191
-
Tissue-specific signal(s) activate the promoter of a metallocarboxypeptidase inhibitor gene family in potato tuber and berry
-
DOI 10.1023/A:1010649503229
-
Molnar A, Lovas A, Banfalvi Z, Lakatos L, Polgar Z, Horvath S, (2001). Tissue-specific signal(s) activate the promoter of a metallocarboxypeptidase inhibitor gene family in potato tuber and berry. Plant Mol Biol 46: 301-311. (Pubitemid 32665057)
-
(2001)
Plant Molecular Biology
, vol.46
, Issue.3
, pp. 301-311
-
-
Molnar, A.1
Lovas, A.2
Banfalvi, Z.3
Lakatos, L.4
Polgar, Z.5
Horvath, S.6
-
32
-
-
0031796848
-
The cystine knot structure of ion channel toxins and related polypeptides
-
DOI 10.1016/S0041-0101(98)00149-4, PII S0041010198001494
-
Norton RS, Pallaghy PK, (1998). The cystine knot structure of ion channel toxins and related polypeptides. Toxicon 36: 1573-1583. (Pubitemid 28511071)
-
(1998)
Toxicon
, vol.36
, Issue.11
, pp. 1573-1583
-
-
Norton, R.S.1
Pallaghy, P.K.2
-
33
-
-
0024869503
-
Isolation and characterisation of a fruit-specific cDNA and the corresponding genomic clone from tomato
-
Pear JR, Ridge N, Rasmussen R, Rose RE, Houck CM, (1989). Isolation and characterisation of a fruit-specific cDNA and the corresponding genomic clone from tomato. Plant Mol Biol 13: 639-651.
-
(1989)
Plant Mol Biol
, vol.13
, pp. 639-651
-
-
Pear, J.R.1
Ridge, N.2
Rasmussen, R.3
Rose, R.E.4
Houck, C.M.5
-
34
-
-
34249796972
-
A potato carboxypeptidase inhibitor gene provides pathogen resistance in transgenic rice
-
DOI 10.1111/j.1467-7652.2007.00264.x
-
Quilis J, Meynard D, Vila L, Aviles FX, Guiderdoni E, San Segundo B, (2007). A potato carboxypeptidase inhibitor gene provides pathogen resistance in transgenic rice. Plant Biotechnol J 5: 537-553. (Pubitemid 46855104)
-
(2007)
Plant Biotechnology Journal
, vol.5
, Issue.4
, pp. 537-553
-
-
Quilis, J.1
Meynard, D.2
Vila, L.3
Aviles, F.X.4
Guiderdoni, E.5
San Segundo, B.6
-
35
-
-
0018892931
-
Structure of potato inhibitor complex of carboxypeptidase A at 5.5-A resolution
-
Rees DC, Lipscomb WN, (1980). Structure of potato inhibitor complex of carboxypeptidase A at 5.5-A resolution. Proc Natl Acad Sci U S A 77: 277-280.
-
(1980)
Proc Natl Acad Sci U S A
, vol.77
, pp. 277-280
-
-
Rees, D.C.1
Lipscomb, W.N.2
-
36
-
-
22844443975
-
Mechanism of action of potato carboxypeptidase inhibitor (PCI) as an EGF blocker
-
DOI 10.1016/j.canlet.2005.01.025, PII S030438350500039X
-
Sitja-Arnau M, Molina MA, Blanco-Aparicio C, Ferrer-Soler L, Lorenzo J, Aviles FX, et al. (2005). Mechanism of action of potato carboxypeptidase inhibitor (PCI) as an EGF blocker. Cancer Lett 226: 169-184. (Pubitemid 41039085)
-
(2005)
Cancer Letters
, vol.226
, Issue.2
, pp. 169-184
-
-
Sitja-Arnau, M.1
Molina, M.A.2
Blanco-Aparicio, C.3
Ferrer-Soler, L.4
Lorenzo, J.5
Aviles, F.X.6
Querol, E.7
De Llorens, R.8
-
37
-
-
0034698943
-
Activation of MAP kinase (ERK-1/ERK-2), tyrosine kinase and VEGF in the human brain following acute ischaemic stroke
-
Slevin M, Krupinski J, Slowik A, Rubio F, Szczudlik A, Gaffney J, (2000). Activation of MAP kinase (ERK-1/ERK-2), tyrosine kinase and VEGF in the human brain following acute ischaemic stroke. Neuroreport 11: 2759-2764.
-
(2000)
Neuroreport
, vol.11
, pp. 2759-2764
-
-
Slevin, M.1
Krupinski, J.2
Slowik, A.3
Rubio, F.4
Szczudlik, A.5
Gaffney, J.6
-
38
-
-
0035010433
-
Evolution and classification of cystine knot-containing hormones and related extracellular signaling molecules
-
DOI 10.1210/me.15.5.681
-
Vitt UA, Hsu SY, Hsueh AJ, (2001). Evolution and classification of cystine knot-containing hormones and related extracellular signalling molecules. Mol Endocrinol 15: 681-694. (Pubitemid 32411309)
-
(2001)
Molecular Endocrinology
, vol.15
, Issue.5
, pp. 681-694
-
-
Vitt, U.A.1
Hsu, S.Y.2
Hsueh, A.J.W.3
-
39
-
-
0037454346
-
Bioconjugation by copper(I)-catalyzed azide-alkyne [3 + 2] cycloaddition
-
DOI 10.1021/ja021381e
-
Wang Q, Chan TR, Hilgraf R, Fokin VV, Sharpless KB, Finn MG, (2003). Bioconjugation by copper(I)-catalyzed azide-alkyne [3 + 2] cycloaddition. J Am Chem Soc 125: 3192-3193. (Pubitemid 36512443)
-
(2003)
Journal of the American Chemical Society
, vol.125
, Issue.11
, pp. 3192-3193
-
-
Wang, Q.1
Chan, T.R.2
Hilgraf, R.3
Fokin, V.V.4
Sharpless, K.B.5
Finn, M.G.6
-
40
-
-
33645563991
-
Murine model of ferric chloride-induced vena cava thrombosis: Evidence for effect of potato carboxypeptidase inhibitor
-
Wang X, Smith PL, Hsu MY, Ogletree ML, Schumacher WA, (2006). Murine model of ferric chloride-induced vena cava thrombosis: evidence for effect of potato carboxypeptidase inhibitor. J Thromb Haemost 4: 403-410.
-
(2006)
J Thromb Haemost
, vol.4
, pp. 403-410
-
-
Wang, X.1
Smith, P.L.2
Hsu, M.Y.3
Ogletree, M.L.4
Schumacher, W.A.5
-
41
-
-
33846876110
-
Evaluation and improvement of the properties of the novel cystine-knot microprotein McoEeTI for oral administration
-
DOI 10.1016/j.ijpharm.2006.09.028, PII S0378517306007794
-
Werle M, Kafedjiiski K, Kolmar H, Bernkop-Schnurch A, (2007). Evaluation and improvement of the properties of the novel cystine-knot microprotein McoEeTI for oral administration. Int J Pharm 332: 72-79. (Pubitemid 46227767)
-
(2007)
International Journal of Pharmaceutics
, vol.332
, Issue.1-2
, pp. 72-79
-
-
Werle, M.1
Kafedjiiski, K.2
Kolmar, H.3
Bernkop-Schnurch, A.4
|