Potato carboxypeptidase inhibitor, a T-knot protein, is an epidermal growth factor antagonist that inhibits tumor cell growth

Journal of Biological Chemistry

Volumn 273, Issue 20, 1998, Pages 12370-12377

  Blanco Aparicio, Carmen ^a   Molina, Miguel Angel ^a   Fernández Salas, Ester ^a   Frazier, Marsha L ^b   Mas, José M ^c   Querol, Enrique ^c   Avilés, Francesc X ^c   De Llorens, Rafael ^a  

^a UNIVERSITY OF GIRONA   (Spain)

^b UNIVERSITY OF TEXAS   (United States)

^c UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYPEPTIDASE; ENZYME INHIBITOR; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR;

ADOLESCENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL PROLIFERATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUDE MOUSE; POTATO; PRIORITY JOURNAL; PROTEIN STRUCTURE; RECEPTOR BINDING;

ANIMALS; CELL CYCLE; CELL DIVISION; COMPUTER SIMULATION; EPIDERMAL GROWTH FACTOR; HUMANS; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; PANCREATIC NEOPLASMS; PLANT PROTEINS; TUMOR CELLS, CULTURED;

ANIMALIA; MUS MUSCULUS; SOLANUM TUBEROSUM;

EID: 0032524336     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.20.12370     Document Type: Article

References (47)

1. Carpenter, G., and Wahl, M. I. (1991) in Peptide Growth Factors and Their Receptors (Sporn, M. B., and Roberts, A., eds) Vol. 1, pp. 69-172, Springer-Verlag, New York
2. Aaronson, S. (1991) Science 254, 1146-1153
3. Carpenter, G. (1987) Annu. Rev. Biochem. 56, 881-914
4. Miettinen, P. J., Berger, J. E., Meneses, J., Phung, Y., Pedersen, R. A., Werb, Z., and Derynck, R. (1995) Nature 376, 337-341
5. Lemmon, M. A., Bu, Z., Ladbury, J. E., Zhou, M., Pinchasi, D., Lax, I., Engelman, D. M., and Schlessinger, J. (1997) EMBO J. 16, 281-294
6. Ullrich, A., and Schlessinger, J. (1990) Cell 61, 203-212
7. Sorkin, A., and Waters, C. M. (1993) BioEssays 15, 375-382
8. Zumkeller, W., and Schofield, P. N. (1995) Anticancer Res. 15, 344-348
9. Derynck, R. (1992) Adv. Cancer. Res. 58, 27-52
10. Lee, D. C., Luetteke, N. C., and Petch, L. A. (1992) Cancer Treat. Res. 63, 233-254
11. Engebraaten, O., Bjerkvig, R., Pedersen, P. H., and Laerum, O. D. (1993) Int. J. Cancer 53, 209-214
12. Nelson, J., Stewart, R., McGivern, M., Bailie, J. R., Walker, B., Murphy, R. F., and Wilson, D. J. (1991) Carcinogenesis 12, 1823-1829
13. Levitzki, A. (1996) Curr. Opin. Cell Biol. 8, 239-244
14. Imamoto, A., Beltran, L. M., and DiGiovanni, J. (1991) Mol. Carcinogen. 4, 52-60
15. Smith, J. J., Derynck, R., and Korc, M. (1987) Proc. Natl. Acad. Sci. U. S. A. 84, 7567-7570
16. Lemoine, N. R., Hugues, C. M., Barton, C. M., Poulsom, R., Jeffery, R. E., Klöppel, G., Hall, P. A., and Gullick, W. J. (1992) J. Pathol. 166, 7-12
17. Korc, M., Chandrasekar, B., Yamanaka, Y., Friess, H., Buchler, M., and Beger, H. G. (1992) J. Clin. Invest. 90, 1352-1360
18. Hynes, N. E., and Groner, B. (1995) Nat. Med. 1, 631-632
19. Groenen, L. C., Nice, E., and Burgess, A. W. (1994) Growth Factors 11, 235-237
20. Baselga, J., and Mendelsohn (1994) J. Pharmacol. Ther. 64, 127-154
21. Billings, P. C., Morrow, A. R., Ryan, C. A., and Kennedy, A. R. (1989) Carcinogenesis 10, 687-691
22. Kennedy, A. R. (1994) Cancer Res. 54, (suppl.) 1999-2005
23. Kennedy, A., Beazer-Barclay, Y., Kinzler, K. W., and Newberne, P. M. (1996) Cancer Res. 56, 679-682
24. Hass, J. M., and Ryan, C. A. (1981) Methods Enzymol. 80, 778-791
25. Molina, M. A., Avilés, F. X., and Querol, E. (1992) Gene (Amst.) 116, 129-138
26. Molina, M. A., Marino, C., Oliva, B., Avilés, F. X., and Querol, E. (1994) J. Biol. Chem. 269, 21467-21472
27. Marino, C., Molina, M., Canals, F., Aviles, F. X., and Querol, E. (1994) Appl. Microbiol. Biotechnol. 41, 632-637
28. Clore, G. M., Groneborn, A. M., Nilges, M., and Ryan, C. A. (1987) Biochemistry 26, 8012-8023
29. Rees, D. C., and Lipscomb, W. N. (1982) J. Mol. Biol. 160, 475-498
30. McDonald, N. Q., and Hendrickson, W. A. (1993) Cell 73, 421-424
31. Sun, P. D. (1995) Annu. Rev. Biophys. Biomol. Struct. 24, 269-291
32. Ling, S. L., and Nussinov, R. (1995) Nat. Struct. Biol. 2, 835-837
33. Roussel, A., and Cambillau, C. (1991) Silicon Graphics Directory, Silicon Graphics, Mountain View, CA
34. Oliva, B., Bates, P. A., Querol, E., Avilés, F. X., and Sternberg, M. J. E. (1997) J. Mol. Biol. 266, 814-830
35. Donate, N. J., Ince, C., Rosenblum, M. G., and Gallick, G. E. (1989) J. Cell. Biochem. 41, 139-157
36. Peles, E., Ben-Levy, R., Tzahar, E., Liu, N., Wen, D., and Yarden, Y. (1993) EMBO J. 12, 961-971
37. Parker, S. L., Tong, T., Bolden, S., and Wingo, P, A. (1996) CA-Cancer J. Clin. 65, 5-27
38. Ryan, C. A., Hass, G. M., and Kuhn, R. W. (1974) J. Cell. Biochem. 249, 5495-5499
39. Derynck, R. (1988) Cell 54, 593-595
40. Dean, C., Modjtahedi, H., Eccles, S., Box, G., and Styles, J. (1994) Int. J. Cancer 8, (suppl.) 103-107
41. Merlino, G. T., Xu, Y., Ishii, S., Clark, A. J., Semba, K., Toyoshima, K., and Yamamoto, K. (1984) Science 224, 417-419
42. Yarden, Y., and Ullrich, A. (1988) Biochemistry 27, 3113-3119
43. Schweitzer, R., Howes, R., Smith, R., Shilo, B.-Z., and Freeman, M. (1995) Nature 376, 699-702
44. Wu, X., Fan, Z., Masui, H., Rosen, N., and Mendelsohn, J. (1995) J. Clin. Invest. 95, 1897-1905
45. Fish, E. N., Ghislain, J., Trogadis, J., and Stevens, J. K. (1993) Cancer Res. 53, 5148-5157
46. French, A. R., Tadaki, D. K., Niyogi, S. K., and Lauffenburger, D. A. (1995) J. Biol. Chem. 270, 4334-4340
47. Canals F. (1992) Biochemistry 31, 4493-4501