Physiopathology of sleep-disordered breathing in children;Fisiopatología de los trastornos respiratorios del sueño en los niños

Acta Otorrinolaringologica Espanola

Volumn 61, Issue SUPPL. 1, 2010, Pages 14-21

  Vicente González, Eugenio ^a   Leza, Isabel Adiego ^a   Maltrana García, José Antonio ^a   Facerías, Elena Aznar ^a   García, Alberto Ortiz ^a  

^a HOSPITAL UNIVERSITARIO MIGUEL SERVET   (Spain)

Author keywords

Arousal; Children sleep apnea; Inflammation; Leukotrienes; Muscle activation; Physiopathology; Sleep disordered breathing; Upper airway

Indexed keywords

AIRWAY; ARTICLE; BLOOD GAS; CHILD; COMORBIDITY; HUMAN; LUNG COLLAPSE; PATHOPHYSIOLOGY; PEDIATRICS; RESPIRATORY FUNCTION; RISK FACTOR; SLEEP APNEA SYNDROME; SLEEP DISORDER; SLEEP DISORDERED BREATHING;

CHILD; HUMANS; INFLAMMATION; SLEEP APNEA SYNDROMES;

EID: 79951985818     PISSN: 00016519     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0001-6519(10)71240-1     Document Type: Article

References (58)

1. Quesada P., Perelló E., Lorente J. Roncopatía crónica y SAHS. Ponencia Oficial Sociedad Española de Otorrinolaringología 1998, Ed. Garsi, Madrid.
2. Katz E.S., D'Ambrosio C.M. Pathophysiology of pediatric obstructive sleep apnea. Proc Am Thorac Soc 2008, 5:253-262.
3. Monahan K.J., Larkin E.K., Rosen C.L., Graham G., Redline S. Utility of non invasive pharyngometry in epidemiologic studies of childhood sleep-disordered breathing. Am J Respir Crit Care Med 2002, 165:1499-1503.
4. Arens R., McDonough J.M., Costarino A.T., Mahboubi S., Tayag-Kier C.E., Maislin G., et al. Magnetic resonance imaging of the upper airway structure of children with obstructive sleep apnea syndrome. Am J Respir Crit Care Med 2001, 164:698-703.
5. Isono S., Shimada A., Utsugi M., Konno A., Nishino T. Comparison of static mechanical properties of the passive pharynx between normal children and children with sleep-disordered breathing. Am J Respir Crit Care Med 1998, 157:1207-1212.
6. Fregosi R.F., Quan S.F., Kaemingk K.L., Morgan W.J., Goodwin J.L., Cabrera R., et al. Sleep-disordered breathing, pharyngeal size and soft tissue anatomy in children. J Appl Physiol 2003, 95:2030-2038.
7. Donnelly L.F., Surdulescu V., Chini B.A., Casper K.A., Poe S.A., Amin R.S. Upper airway motion depicted at cine MR imaging performed during sleep: comparison between young Patients with and those without obstructive sleep apnea. Radiology 2003, 227:239-245.
8. Kawashima S., Niikuni N., Chia-hung L., Takahasi Y., Kohno M., Nakajima I., et al. Cephalometric comparisons of craniofacial and upper airway structures in young children with obstructive sleep apnea syndrome. Ear Nose Throat J 2000, 79:499-506.
9. Gozal D. Obstructive sleep apnea in children: implications for the developing central nervous system. Semin Pediatr Neurol 2008, 15:100-106.
10. Marcus C.L., Lutz J., Carroll J.L., Bamford O. Arousal and ventilatory responses during sleep in children with obstructive sleep apnea. J Appl Physiol 1998, 84:1926-1936.
11. Behlfelt K., Linder-Aronson S., McWilliam J., Neander P., Laage-Hellman J. Cranio-facial morphology in children with and without enlarged tonsils. Eur J Orthod 1990, 12:233-243.
12. Zettergren-Wijk L., Forsberg C.M., Linder-Aronson S. Changes in dentofacial morphology after adeno-/tonsillectomy in young children with obstructive sleep apnoea-a 5-year follow-up study. Eur J Orthod 2006, 28:319-326.
13. Kheirandish-Gozal L., Sans Capdevila O., Maarafeya M.M., Gozal D. Obstructive sleep apnea in children: relative contributions of body mass index and adenotonsillar hypertrophy. Chest 2009, 136:137-144.
14. Marcus C. Sleep-disordered breathing in children. State of the art. Am J Respir Crit Care Med 2001, 164:16-30.
15. Consenso Nacional sobre el síndrome de apneas-hipopneas del sueño. Arch Bronconeumol 2005, 41(Supl 4):5-110. Grupo Español de Sueño (GES).
16. Villa Asensi J.R., De Miguel Díez J. Síndrome de apnea obstruc tiva del sueño en la infancia. An Esp Pediatr 2001, 54:58-64.
17. Dayyat E., Kheirandish-Gozal L., Gozal D. Childhood obstructive sleep apnea: one or two distint disease entities?. Sleep Med Clin 2007, 2:433-444.
18. Maltrana J.A., El Uali M., Pérez L., Adiego L., Vicente E., Ortiz A. Síndrome de apnea obstructiva en niños. Acta Otorrinolaringol Esp 2009, 60:202-207.
19. Esteller E., Barceló M., Segarra F. Alteraciones neurocognitivas y conductuales en los trastornos respiratorios del sueño infantil. Acta Otorrinolaringol Esp 2009, 60:325-331.
20. Marín J.M., Carrizo S.J., Vicente E., Agustí A.G.N. Long-term cardiovascular outcomes in men with obstructive sleep apneahypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet 2005, 365:1046-1053.
21. Fernández E. Roncopatía crónica. Síndrome de apnea obstructiva del sueño. Tratado de otorrinolaringología y cirugía de cabeza y cuello 2008, Ed. Panamericana, Madrid.
22. Marcus C., Katz E., Lutz J., Black C., Galster P., Carson K.A. Upper airway dinamic responses in children with the obstructive sleep apnea síndrome. Pediatr Res 2005, 57:99-107.
23. Delgado F. TRS en pediatría 2003, Ed. Jarpyo Editores, Madrid.
24. Schwartz A.R., Smith P.L., Wise R.A., Gold A.R., Permutt S. Induction of upper airway occlusion in sleeping normal humans. J Appl Physiol 1988, 64:535-542.
25. Llorente E., Vicente E., Marín J.M., Naya M.J. Cambios histológicos en el paladar blando en pacientes con apnea obstructiva del sueño. Anales ORL Iber-Amer 2001, 5:467-476.
26. Huang J., Karamessinis L.R., Pepe M.E., Glinka S.M., Samuel J.M., Gallagher P.R., et al. Upper airway collapsibility during REM sleep in children with the obstructive sleep apnea syndrome. Sleep 2009, 32:1173-1181.
27. Muzumdar H., Arens R. Diagnostic issues in pediatric obstructive sleep apnea. Proc Am Thorac Soc 2008, 5:263-273.
28. Nixon G.M., Brouillette R.T. Sleep 8: paediatric obstructive sleep apnoea. Thorax 2005, 60:511-516.
29. Goh D.Y., Galster P., Marcus C.L. Sleep architecture and respiratory disturbances in children with obstructive sleep apnea. Am J Respir Crit Care Med 2000, 162:682-686.
30. Karamessinis L., Galster P., Schultz B., Elliott J., Mason T.A., Brooks L.J., et al. Relationship between REM density, duty cycle, and obstructive sleep apnea in children. Sleep 2007, 30:837-843.
31. Li H.Y., Lee L.A. Sleep-disordered breathing children. Chang Gung Med J 2009, 32:247-257.
32. Scholle S., Zwacka G. Arousal and obstructive sleep apnea syndrome in children. Clin Neurophysiol 2001, 112:984-991.
33. Gottlieb D.J., Chase C., Vezina R.M., Heeren T.C., Corwin M.J., Auerbach S.H., et al. Sleep-disordered breathing symptoms are associated with poorer cognitive function in 5-year-old children. J Pediatr 2004, 145:458-464.
34. O'Brien L.M., Mervis C.B., Holbrook C.R., Bruner J.L., Klaus C.J., Rutherford J., et al. Neurobehavioral implications of habitual snoring in children. Pediatrics 2004, 114:44-49.
35. Kennedy J.D., Blunden S., Hirte C., Parsons D.W., Martin A.J., Crowe E., et al. Reduced neurocognition in children who snore. Pediatr Pulmonol 2004, 37:330-337.
36. Rosen C.L., Storfer-Isser A., Taylor H.G., Kirchner H.L., Emancipator J.L., Redline S. Increased behavioral morbidity in school-aged children with sleep-disordered breathing. Pediatrics 2004, 114:1640-1648.
37. Goldbart A.D., Tal A. Inflammation and sleep disordered breathing in Children: A state-of the art -review. Pediatr Pulmonol 2008, 43:1151-1160.
38. Tauman R., Ivanenko A., O'Brien L.M., Gozal D. Plasma C-reactive protein levels among children with sleep-disordered breathing. Pediatrics 2004, 113:564-569.
39. Gozal J.M., Daniel G.P. Behavioral and anatomical correlates of chronic episodic hypoxia during sleep in the rat. J Neurosci 2001, 21:2442-2450.
40. Veasey C., Davis C., Zhan G., Hsu Y.J., Fenik P., Pratico D., et al. Long-term intermittent hypoxia during sleep in mice: protracted hypersomnolence with oxidative injury to sleep-wake brain regions. Sleep 2004, 27:194-201.
41. Shirasaki H., Kanaizumi E., Watanabe K., Matsui T., Sato J., Narita S., et al. Expression and localization of the cysteinyl leukotriene 1 receptor in human nasal mucosa. Clin Exp Allergy 2002, 32:1007-1012.
42. Figueroa D.J., Breyer R.M., Defoe S.K., Kargman S., Daugherty B.L., Waldburger K., et al. Expression of the cysteinyl leukotriene 1 receptor in normal human lung and peripheral blood leukocytes. Am J Respir Crit Care Med 2001, 163:226-233.
43. Goldbart A.D., Goldman J.L., Li R.C., Brittian K.R., Tauman R., Gozal D. Differential expression of cysteinyl leukotriene receptors 1 and 2 in tonsils of children with obstructive sleep apnea syndrome or recurrent infection. Chest 2004, 126:13-18.
44. Li A.M., Hung E., Tsang T., Yin J., So H.K., Wong E., et al. Induced sputum inflammatory measures correlate with disease severity in children with obstructive sleep apnea. Thorax 2007, 62:75-79.
45. Ebenfelt A., Ivarsson M. Neutrophil migration in tonsils. J Anat 2001, 198:497-500.
46. Petrosyan M., Perraki E., Simoes D., Koutsourelakis I., Vagiakis E., Roussos C., et al. Exhaled breath markers in patients with obstructive sleep apnea. Sleep Breath 2008, 207-215.
47. Goldbart A.D., Mager E., Veling M.C., Goldman J.L., Keirandish-Gozal L., Serpero L.D., et al. Neurtrophins and tonsilar hypertrophy in children with obstructive sleep apnea. Pediatr Res 2007, 62:489-494.
48. Kaditis A.G., Alexopoulus E.L., Kalampouka E., Kostadina E., Germenis A., Zintzaras A., et al. Morning levels of C-reactive protein in children with obstructive sleep-disordered breathing. Am J Respir Crit Care Med 2005, 171:282-286.
49. Larkin E.K., Rosen C.L., Kirchner H.L., Storfer-Isser A., Emancipator J.L., Johnson N.L., et al. Variations of C-reactive protein levels in adolescents: association with sleep-disordered breathing and sleep duration. Circulation 2005, 111:1978-1984.
50. Tauman R., O'Brien L.M., Gozal D. Hypoxemia and obesity modulate plasma C-reactive protein and interleukin-6 levels in sleep disordered breathing. Sleep Breath 2007, 11:77-84.
51. Li A.M., Chan M.H., Yin J., So H.K., Ng S.K., Chan I.H., et al. C reactive protein in children with obstructive sleep apnea and the effects of treatment. Pediatr Pulmonol 2008, 43:34-40.
52. Gozal D., Serpero L.D., Sans Capdevila O., Keirandish-Gozal L. Systemic inflammation in non-obese children with obstructive sleep apnea. Sleep Med 2008, 9:254-259.
53. Tam C.S., Wong M., McBain R., Bailey S., Waters K.A. Inflammatory measures in children with obstructive sleep apnoea. J Paediatr Child Health 2006, 42:277-282.
54. Kaditis A.G., Alexopoulus E.I., Kalampouka E., Kostadima E., Angelopoulos N., Germenis A., et al. Morning levels of fibrinogen in children with sleep-disordered breathing. Eur Respir J 2004, 24:790-797.
55. Goldbart A., Tal A. Elevated circulating leukotrienes in children with sleep disordered breathing. Am J Respir Crit Care Med 2007, 175-178.
56. Keirandish-Gozal L., Capdevilla O.S., Tauman R., Gozal D. Plasma C-reactive protein in nonobese children with obstructive sleep apnea before and after adenotonsillectomy. J Clin Sleep Med 2006, 2:301-304.
57. Crabtree V.M., Sans Capdevilla O., Witcher L.A., Keirandish-Gozal L. C-reactive protein, obstructive sleep apnea, and cognitive dysfunction in school-aged children. Am J Respir Crit Care Med 2007, 176:188-193.
58. Gozal D., Sans Capdevila O.S., Keirandish-Gozal L. Metabolic alterations and systemic inflammation in obstructive sleep apnea among nonobese and obese prepuberal children. Am J Respir Crit Care Med 2008, 177:1142-1149.