메뉴 건너뛰기




Volumn 79, Issue 3, 2011, Pages 368-380

A serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ros and ceramide levels

Author keywords

[No Author keywords available]

Indexed keywords

ARSENIC TRIOXIDE; CALCIUM ION; CERAMIDE; FAS ANTIGEN; FENRETINIDE; FLICE INHIBITORY PROTEIN; INTERLEUKIN 24; PROCASPASE 8; REACTIVE OXYGEN METABOLITE; TANESPIMYCIN;

EID: 79951983754     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.110.069484     Document Type: Article
Times cited : (24)

References (48)
  • 1
    • 60749108379 scopus 로고    scopus 로고
    • Regulation of autophagy by reactive oxygen species (ROS): Implications for cancer progression and treatment
    • Azad MB, Chen Y, and Gibson SB (2009) Regulation of autophagy by reactive oxygen species (ROS): implications for cancer progression and treatment. Antioxid Redox Signal 11:777-790.
    • (2009) Antioxid Redox Signal , vol.11 , pp. 777-790
    • Azad, M.B.1    Chen, Y.2    Gibson, S.B.3
  • 4
    • 77953694468 scopus 로고    scopus 로고
    • Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad. 5/3) improves therapeutic efficacy in low CAR prostate cancer cells
    • Dash R, Dmitriev I, Su ZZ, Bhutia SK, Azab B, Vozhilla N, Yacoub A, Dent P, Curiel DT, Sarkar D, et al. (2010) Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad. 5/3) improves therapeutic efficacy in low CAR prostate cancer cells. Cancer Gene Ther 17:447-456.
    • (2010) Cancer Gene Ther , vol.17 , pp. 447-456
    • Dash, R.1    Dmitriev, I.2    Su, Z.Z.3    Bhutia, S.K.4    Azab, B.5    Vozhilla, N.6    Yacoub, A.7    Dent, P.8    Curiel, D.T.9    Sarkar, D.10
  • 7
    • 66149138884 scopus 로고    scopus 로고
    • Historical perspective and recent insights into our understanding of the molecular and biochemical basis of the antitumor properties of mda-7/IL-24
    • Emdad L, Lebedeva IV, Su ZZ, Gupta P, Sauane M, Dash R, Grant S, Dent P, Curiel DT, Sarkar D, et al. (2009) Historical perspective and recent insights into our understanding of the molecular and biochemical basis of the antitumor properties of mda-7/IL-24. Cancer Biol Ther 8:391-400.
    • (2009) Cancer Biol Ther , vol.8 , pp. 391-400
    • Emdad, L.1    Lebedeva, I.V.2    Su, Z.Z.3    Gupta, P.4    Sauane, M.5    Dash, R.6    Grant, S.7    Dent, P.8    Curiel, D.T.9    Sarkar, D.10
  • 9
    • 28544435618 scopus 로고    scopus 로고
    • Is mda-7/IL-24 a "magic bullet" for cancer?
    • Fisher PB (2005) Is mda-7/IL-24 a "magic bullet" for cancer? Cancer Res 65:10128-10138.
    • (2005) Cancer Res , vol.65 , pp. 10128-10138
    • Fisher, P.B.1
  • 11
    • 18744412975 scopus 로고    scopus 로고
    • Comparison of presentation and outcome for patients 18 to 40 and 60 to 70 years old with solid renal masses
    • DOI 10.1097/01.ju.0000158157.57981.80
    • Gillett MD, Cheville JC, Karnes RJ, Lohse CM, Kwon ED, Leibovich BC, Zincke H, and Blute ML (2005) Comparison of presentation and outcome for patients 18 to 40 and 60 to 70 years old with solid renal masses. J Urol 173:1893-1896. (Pubitemid 40675205)
    • (2005) Journal of Urology , vol.173 , Issue.6 , pp. 1893-1896
    • Gillett, M.D.1    Cheville, J.C.2    Jeffrey, K.R.3    Lohse, C.M.4    Kwon, E.D.5    Leibovich, B.C.6    Zincke, H.7    Blute, M.L.8
  • 12
    • 17144375725 scopus 로고    scopus 로고
    • Activation of the Fas-FasL signaling pathway by MDA-7/IL-24 kills human ovarian cancer cells
    • Gopalan B, Litvak A, Sharma S, Mhashilkar AM, Chada S, and Ramesh R (2005) Activation of the Fas-FasL signaling pathway by MDA-7/IL-24 kills human ovarian cancer cells. Cancer Res 65:3017-3024. (Pubitemid 40524577)
    • (2005) Cancer Research , vol.65 , Issue.8 , pp. 3017-3024
    • Gopalan, B.1    Litvak, A.2    Sharma, S.3    Mhashilkar, A.M.4    Chada, S.5    Ramesh, R.6
  • 14
    • 42949106089 scopus 로고    scopus 로고
    • Targeted combinatorial therapy of non-small cell lung carcinoma using a GST-fusion protein of full-length or truncated MDA-7/IL-24 with Tarceva
    • DOI 10.1002/jcp.21369
    • Gupta P, Emdad L, Lebedeva IV, Sarkar D, Dent P, Curiel DT, Settleman J, and Fisher PB (2008) Targeted combinatorial therapy of non-small cell lung carcinoma using a GST-fusion protein of full-length or truncated MDA-7/IL-24 with Tarceva. J Cell Physiol 215:827-836. (Pubitemid 351632704)
    • (2008) Journal of Cellular Physiology , vol.215 , Issue.3 , pp. 827-836
    • Gupta, P.1    Emdad, L.2    Lebedeva, I.V.3    Sarkar, D.4    Dent, P.5    Curiel, D.T.6    Settleman, J.7    Fisher, P.B.8
  • 20
    • 12344338770 scopus 로고    scopus 로고
    • Inhibition of the ubiquitin-proteasome pathway activates stress kinases and induces apoptosis in renal cancer cells
    • Ishizawa J, Yoshida S, Oya M, Mizuno R, Shinojima T, Marumo K, and Murai M (2004) Inhibition of the ubiquitin-proteasome pathway activates stress kinases and induces apoptosis in renal cancer cells. Int J Oncol 25:697-702.
    • (2004) Int J Oncol , vol.25 , pp. 697-702
    • Ishizawa, J.1    Yoshida, S.2    Oya, M.3    Mizuno, R.4    Shinojima, T.5    Marumo, K.6    Murai, M.7
  • 21
    • 0029558740 scopus 로고
    • Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression
    • Jiang H, Lin JJ, Su ZZ, Goldstein NI, and Fisher PB (1995) Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression. Oncogene 11:2477-2486. (Pubitemid 26023815)
    • (1995) Oncogene , vol.11 , Issue.12 , pp. 2477-2486
    • Jiang, H.1    Lin, J.J.2    Su, Z.-Z.3    Goldstein, N.I.4    Fisher, P.B.5
  • 22
    • 42649146188 scopus 로고    scopus 로고
    • The PERK/eIF2 alpha signaling pathway of Unfolded Protein Response is essential for N-(4-hydroxyphenyl)retinamide (4HPR)-induced cytotoxicity in cancer cells
    • Lai WL and Wong NS (2008) The PERK/eIF2 alpha signaling pathway of Unfolded Protein Response is essential for N-(4-hydroxyphenyl)retinamide (4HPR)-induced cytotoxicity in cancer cells. Exp Cell Res 314:1667-1682.
    • (2008) Exp Cell Res , vol.314 , pp. 1667-1682
    • Lai, W.L.1    Wong, N.S.2
  • 23
    • 38449096542 scopus 로고    scopus 로고
    • Mda-7/IL-24, novel anticancer cytokine: Focus on bystander antitumor, radiosensitization and antiangiogenic properties and overview of the phase I clinical experience
    • review
    • Lebedeva IV, Emdad L, Su ZZ, Gupta P, Sauane M, Sarkar D, Staudt MR, Liu SJ, Taher MM, Xiao R, et al. (2007a) mda-7/IL-24, novel anticancer cytokine: focus on bystander antitumor, radiosensitization and antiangiogenic properties and overview of the phase I clinical experience (review). Int J Oncol 31:985-1007.
    • (2007) Int J Oncol , vol.31 , pp. 985-1007
    • Lebedeva, I.V.1    Emdad, L.2    Su, Z.Z.3    Gupta, P.4    Sauane, M.5    Sarkar, D.6    Staudt, M.R.7    Liu, S.J.8    Taher, M.M.9    Xiao, R.10
  • 25
    • 85047695547 scopus 로고    scopus 로고
    • The cancer growth suppressing gene mda-7 induces apoptosis selectively in human melanoma cells
    • DOI 10.1038/sj/onc/1205116
    • Lebedeva IV, Su ZZ, Chang Y, Kitada S, Reed JC, and Fisher PB (2002) The cancer growth suppressing gene mda-7 induces apoptosis selectively in human melanoma cells. Oncogene 21:708-718. (Pubitemid 34146283)
    • (2002) Oncogene , vol.21 , Issue.5 , pp. 708-718
    • Lebedeva, I.V.1    Su, Z.-Z.2    Chang, Y.3    Kitada, S.4    Reed, J.C.5    Fisher, P.B.6
  • 26
    • 13244268270 scopus 로고    scopus 로고
    • Induction of reactive oxygen species renders mutant and wild-type K-ras pancreatic carcinoma cells susceptible to Ad.mda-7-induced apoptosis
    • DOI 10.1038/sj.onc.1208183
    • Lebedeva IV, Su ZZ, Sarkar D, Gopalkrishnan RV, Waxman S, Yacoub A, Dent P, and Fisher PB (2005a) Induction of reactive oxygen species renders mutant and wild-type K-ras pancreatic carcinoma cells susceptible to Ad.mda-7-induced apoptosis. Oncogene 24:585-596. (Pubitemid 40188563)
    • (2005) Oncogene , vol.24 , Issue.4 , pp. 585-596
    • Lebedeva, I.V.1    Su, Z.-Z.2    Sarkar, D.3    Gopalkrishnan, R.V.4    Waxman, S.5    Yacoub, A.6    Dent, P.7    Fisher, P.B.8
  • 31
    • 54049125376 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase kinase 1/2 inhibitors and 17-allylamino-17-demethoxygeldanamycin synergize to kill human gastrointestinal tumor cells in vitro via suppression of c-FLIP-s levels and activation of CD95
    • Park MA, Zhang G, Mitchell C, Rahmani M, Hamed H, Hagan MP, Yacoub A, Curiel DT, Fisher PB, Grant S, et al. (2008) Mitogen-activated protein kinase kinase 1/2 inhibitors and 17-allylamino-17-demethoxygeldanamycin synergize to kill human gastrointestinal tumor cells in vitro via suppression of c-FLIP-s levels and activation of CD95. Mol Cancer Ther 7:2633-2648.
    • (2008) Mol Cancer Ther , vol.7 , pp. 2633-2648
    • Park, M.A.1    Zhang, G.2    Mitchell, C.3    Rahmani, M.4    Hamed, H.5    Hagan, M.P.6    Yacoub, A.7    Curiel, D.T.8    Fisher, P.B.9    Grant, S.10
  • 35
    • 7044268950 scopus 로고    scopus 로고
    • Mechanistic aspects of mda-7/IL-24 cancer cell selectivity analysed via a bacterial fusion protein
    • DOI 10.1038/sj.onc.1207958
    • Sauane M, Gopalkrishnan RV, Choo HT, Gupta P, Lebedeva IV, Yacoub A, Dent P, and Fisher PB (2004a) Mechanistic aspects of mda-7/IL-24 cancer cell selectivity analysed via a bacterial fusion protein. Oncogene 23:7679-7690. (Pubitemid 39424926)
    • (2004) Oncogene , vol.23 , Issue.46 , pp. 7679-7690
    • Sauane, M.1    Gopalkrishnan, R.V.2    Choo, H.-T.3    Gupta, P.4    Lebedeva, I.V.5    Yacoub, A.6    Dent, P.7    Fisher, P.B.8
  • 36
    • 2342557922 scopus 로고    scopus 로고
    • Melanoma Differentiation Associated Gene-7/Interleukin-24 Promotes Tumor Cell-Specific Apoptosis through Both Secretory and Nonsecretory Pathways
    • DOI 10.1158/0008-5472.CAN-04-0200
    • Sauane M, Lebedeva IV, Su ZZ, Choo HT, Randolph A, Valerie K, Dent P, Gopalkrishnan RV, and Fisher PB (2004b) Melanoma differentiation associated gene-7/interleukin-24 promotes tumor cell-specific apoptosis through both secretory and nonsecretory pathways. Cancer Res 64:2988-2993. (Pubitemid 38581393)
    • (2004) Cancer Research , vol.64 , Issue.9 , pp. 2988-2993
    • Sauane, M.1    Lebedeva, I.V.2    Su, Z.-Z.3    Choo, H.-T.4    Randolph, A.5    Valerie, K.6    Dent, P.7    Gopalkrishnan, R.V.8    Fisher, P.B.9
  • 39
    • 27844459421 scopus 로고    scopus 로고
    • Unique aspects of mda-7/IL-24 antitumor bystander activity: Establishing a role for secretion of MDA-7/IL-24 protein by normal cells
    • DOI 10.1038/sj.onc.1208911, PII 1208911
    • Su Z, Emdad L, Sauane M, Lebedeva IV, Sarkar D, Gupta P, James CD, Randolph A, Valerie K, Walter MR, Dent P, and Fisher PB (2005) Unique aspects of mda-7/IL-24 antitumor bystander activity: establishing a role for secretion of MDA-7/IL-24 protein by normal cells. Oncogene 24:7552-7566. (Pubitemid 41638030)
    • (2005) Oncogene , vol.24 , Issue.51 , pp. 7552-7566
    • Su, Z.1    Emdad, L.2    Sauane, M.3    Lebedeva, I.V.4    Sarkar, D.5    Gupta, P.6    James, C.D.7    Randolph, A.8    Valerie, K.9    Walter, M.R.10    Dent, P.11    Fisher, P.B.12
  • 41
    • 33646127801 scopus 로고    scopus 로고
    • Ionizing radiation enhances therapeutic activity of mda-7/IL-24: Overcoming radiation- and mda-7/IL-24-resistance in prostate cancer cells overexpressing the antiapoptotic proteins bcl-xL or bcl-2
    • Su ZZ, Lebedeva IV, Sarkar D, Emdad L, Gupta P, Kitada S, Dent P, Reed JC, and Fisher PB (2006) Ionizing radiation enhances therapeutic activity of mda-7/IL-24: overcoming radiation- and mda-7/IL-24-resistance in prostate cancer cells overexpressing the antiapoptotic proteins bcl-xL or bcl-2. Oncogene 25:2339-2348.
    • (2006) Oncogene , vol.25 , pp. 2339-2348
    • Su, Z.Z.1    Lebedeva, I.V.2    Sarkar, D.3    Emdad, L.4    Gupta, P.5    Kitada, S.6    Dent, P.7    Reed, J.C.8    Fisher, P.B.9
  • 43
    • 45849147350 scopus 로고    scopus 로고
    • A Molecule Targeting VHL-Deficient Renal Cell Carcinoma that Induces Autophagy
    • DOI 10.1016/j.ccr.2008.06.004, PII S1535610808001943
    • Turcotte S, Chan DA, Sutphin PD, Hay MP, Denny WA, and Giaccia AJ (2008) A molecule targeting VHL-deficient renal cell carcinoma that induces autophagy. Cancer Cell 14:90-102. (Pubitemid 351885499)
    • (2008) Cancer Cell , vol.14 , Issue.1 , pp. 90-102
    • Turcotte, S.1    Chan, D.A.2    Sutphin, P.D.3    Hay, M.P.4    Denny, W.A.5    Giaccia, A.J.6
  • 45
    • 76249095217 scopus 로고    scopus 로고
    • PKR endoplasmic reticulum kinase dependent regulation of ceramide synthase 6 and thioredoxin controls melanoma differentiation associated gene-7 glioma cell killing
    • Yacoub A, Hamed HA, Allegood J, Mitchell C, Spiegel S, Lesniak MS, Ogretmen B, Dash R, Sarkar D, Broaddus WC, et al. (2010) PKR endoplasmic reticulum kinase dependent regulation of ceramide synthase 6 and thioredoxin controls melanoma differentiation associated gene-7 glioma cell killing. Cancer Res 70:1120-1129.
    • (2010) Cancer Res , vol.70 , pp. 1120-1129
    • Yacoub, A.1    Hamed, H.A.2    Allegood, J.3    Mitchell, C.4    Spiegel, S.5    Lesniak, M.S.6    Ogretmen, B.7    Dash, R.8    Sarkar, D.9    Broaddus, W.C.10
  • 46
    • 1642417725 scopus 로고    scopus 로고
    • MDA-7 (interleukin-24) inhibits the proliferation of renal carcinoma cells and interacts with free radicals to promote cell death and loss of reproductive capacity
    • Yacoub A, Mitchell C, Brannon J, Rosenberg E, Qiao L, McKinstry R, Linehan WM, Su ZS, Sarkar D, Lebedeva IV, et al. (2003) MDA-7 (interleukin-24) inhibits the proliferation of renal carcinoma cells and interacts with free radicals to promote cell death and loss of reproductive capacity. Mol Cancer Ther 2:623-632.
    • (2003) Mol Cancer Ther , vol.2 , pp. 623-632
    • Yacoub, A.1    Mitchell, C.2    Brannon, J.3    Rosenberg, E.4    Qiao, L.5    McKinstry, R.6    Linehan, W.M.7    Su, Z.S.8    Sarkar, D.9    Lebedeva, I.V.10
  • 48
    • 34347384854 scopus 로고    scopus 로고
    • Treatment of acute promyelocytic leukaemia with all-trans retinoic acid and arsenic trioxide: A paradigm of synergistic molecular targeting therapy
    • DOI 10.1098/rstb.2007.2026
    • Zhou GB, Zhang J, Wang ZY, Chen SJ, and Chen Z (2007) Treatment of acute promyelocytic leukaemia with all-trans retinoic acid and arsenic trioxide: a paradigm of synergistic molecular targeting therapy. Philos Trans R Soc Lond B Biol Sci 362:959-971. (Pubitemid 47056795)
    • (2007) Philosophical Transactions of the Royal Society B: Biological Sciences , vol.362 , Issue.1482 , pp. 959-971
    • Zhou, G.-B.1    Zhang, J.2    Wang, Z.-Y.3    Chen, S.-J.4    Chen, Z.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.