Homology modeling and monoclonal antibody binding of the der f 7 dust mite allergen

Immunology and Cell Biology

Volumn 89, Issue 2, 2011, Pages 225-230

  Shen, Horng Der ^a   Tam, Ming F ^b   Huang, Chao Hsien ^c   Chou, Hong ^a   Tai, Hsiao Yun ^a   Chen, Yu Sen ^a   Sheu, Sheh Yi ^c   Thomas, Wayne R ^d  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b INSTITUTE OF MOLECULAR BIOLOGY   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

^d UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

BPI protein; Der f 7; Der p 7; epitope; modeling structure; odorant binding protein

Indexed keywords

BACTERICIDAL PERMEABILITY INCREASING PROTEIN; HOUSE DUST ALLERGEN; IMMUNOGLOBULIN E; MONOCLONAL ANTIBODY;

ALLERGENICITY; AMINO TERMINAL SEQUENCE; ANTIGEN BINDING; ARTICLE; CARBOXY TERMINAL SEQUENCE; EPITOPE MAPPING; NONHUMAN; PROCESS MODEL; STRUCTURAL HOMOLOGY;

ALLERGENS; AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, DERMATOPHAGOIDES; EPITOPES; HUMANS; IMMUNOBLOTTING; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, SECONDARY; PYROGLYPHIDAE; STRUCTURAL HOMOLOGY, PROTEIN;

ACARI;

EID: 79951942316     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2010.77     Document Type: Article

References (43)

1. Thomas WR, Heinrich TK, Smith WA, Hales BJ. Pyroglyphid house dust mite allergens. Protein Pept Lett 2007; 14: 943-953. (Pubitemid 350164232)
2. Hales BJ, Martin AC, Pearce LJ, Laing IA, Hayden CM, Goldblatt J et al. IgE and IgG anti-house dust mite specificities in allergic disease. J Allergy Clin Immunol 2006; 118: 361-367. (Pubitemid 44142702)
3. Weghofer M, Dall'Antonia Y, Grote M, Stocklinger A, Kneidinger M, Balic N et al. Characterization of Der p 21, a new important allergen derived from the gut of house dust mites. Allergy 2008; 63: 758-767.
4. Weghofer M, Thomas WR, Pittner G, Horak F, Valenta R, Vrtala S. Comparison of purified Dermatophagoides pteronyssinus allergens and extract by two-dimensional immunoblotting and quantitative immunoglobulin E inhibitions. Clin Exp Allergy 2005; 35: 1384-1391.
5. Weghofer M, Grote M, Dall'Antonia Y, Fernández-Caldas E, Krauth MT, van Hage M et al. Characterization of folded recombinant Der p 5, a potential diagnostic marker allergen for house dust mite allergy. Int Arch Allergy Immunol 2008; 147: 101-109.
6. Arruda LK, Fernandez-Caldas E, Naspitz CK, Montealegre F, Vailes LD, Chapman MD. Identification of Blomia tropicalis allergen Blo t 5 by cDNA cloning. Int Arch Allergy Immunol 1995; 107: 456-457.
7. Chan SL, Ong TC, Gao YF, Tiong YS, Wang de Y, Chew FT et al. Nuclear magnetic resonance structure and IgE epitopes of Blo t 5, a major dust mite allergen. J Immunol 2008; 181: 2586-2596.
8. Naik MT, Chang CF, Kuo IC, Kung CC, Yi FC, Chua KY et al. Roles of structure and structural dynamics in the antibody recognition of the allergen proteins: an NMR study on Blomia tropicalis major allergen. Structure 2008; 16: 125-136.
9. Shen HD, Chua KY, Lin KL, Hsieh KH, Thomas WR. Molecular cloning of a house dust mite allergen with common antibody binding specificities with multiple components in mite extracts. Clin Exp Allergy 1993; 23: 934-940. (Pubitemid 24002187)
10. Shen HD, CHua KY, Lin WL, Hsieh IM, Thomas WR. Molecular cloning and immunological characterization of the house dust mite allergen Der f 7. Clin Exp Allergy 1995; 25: 1000-1006.
11. Shen HD, Chua KY, Lin WL, Hsieh KH, Thomas WR. Characterization of the house dust mite allergen Der p 7 by monoclonal antibodies. Clin Exp Allergy 1995; 25: 416-422.
12. Shen HD, Lin WL, Tsai LC, Tam MF, Chua KY, Chen HL et al. Characterization of the allergen Der f 7 from house dust mite extracts by species-specific and cross-reactive monoclonal antibodies. Clin Exp Allergy 1997; 27: 824-832. (Pubitemid 27306163)
13. Shen HD, Chua KY, Lin WL, Chen HL, Hsieh KH, Thomas WR. IgE and monoclonal antibody binding by the mite allergen Der p 7. Clin Exp Allergy 1996; 26: 308-315.
14. Sali A, Blundell TL. Comparative protein modelling by satisfaction of spatial restraints. J Mol Biol 1993; 234: 779-815. (Pubitemid 24007801)
15. Beamer LJ, Carroll SF, Eisenberg D. Crystal structure of human BPI and two bound phospholipids at 2.4 angstrom resolution. Science 1997; 276: 1861-1864.
16. Elsbach P, Weiss J. Role of the bactericidal/permeability-increasing protein in host defense. Curr Opin Immunol 1998; 10: 45-49. (Pubitemid 28112078)
17. Ooi CE, Weiss J, Elsbach P, Frangione B, Mannion B. A 25-kDa NH2-terminal fragment carries all the antibacterial activities of the human neutrophil 60-kDa bactericidal/permeability-increasing protein. J Biol Chem 1987; 262: 14891-14894. (Pubitemid 17160164)
18. Ooi CE, Weiss J, Doerfler ME, Elsbach P. Endotoxin-neutralizing properties of the 25kD N-terminal fragment and a newly isolated 30kD C-terminal fragment of the 55-60kD bactericidal/permeability-increasing protein of human neutrophils. J Exp Med 1991; 174: 649-655.
19. Iovine NM, Elsbach P, Weiss J. An opsonic function of the neutrophil bactericidal/permeability-increasing protein depends on both its N- and C-terminal domains. Proc Natl Acad Sci USA 1997; 94: 10973-10978.
20. Tall A. Plasma lipid transfer proteins. Annu Rev Biochem 1995; 64: 235-257.
21. Canny G, Levy O. Bactericidal/permeability-increasing protein (BPI) and BPI homologs at mucosal sites. Trends Immunol 2008; 29: 541-547.
22. Rice DW, Eisenberg D. A 3D-1D substitution matrix for protein fold recognition that includes predicted secondary structure of the sequence. J Mol Biol 1997; 267: 1026-1038. (Pubitemid 27192670)
23. Kolodziejczyk R, Bujacz G, Jakob M, Ozyhar A, Jaskolski M, Kochman M. Insect juvenile hormone binding protein shows ancestral fold present in human lipid-binding proteins. J Mol Biol 2008; 377: 870-881.
24. Bingle L, Barnes FA, Lunn H, Musa M, Webster S, Douglas CW et al. Characterisation and expression of SPLUNC2, the human orthologue of rodent parotid secretory protein. Histochem Cell Biol 2009; 132: 339-349.
25. Thomas WR, Hales BJ, Smith WA. Structural biology of allergens. Curr Allergy Asthma Rep 2005; 5: 388-393. (Pubitemid 41683982)
26. Trompette A, Divanovic S, Visintin A, Blanchard C, Hegde RS, Madan R et al. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Nature 2009; 457: 585-588.
27. Lai HY, Tam MF, Chou H, Lee SS, Tai HY, Shen HD. Molecular and structural analysis of IgE-binding epitopes of Pen ch 13, an alkaline serine protease major allergen from Penicillium chrysogenum. Clin Exp Allergy 2004; 34: 1926-1933.
28. Padavattan S, Schirmer T, Schmidt M, Akdis C, Valenta R, Mittermann I et al. Identification of a B-cell epitope of hyaluronidase, a major bee venom allergen, from its crystal structure in complex with a specific Fab. J Mol Biol 2007; 368: 742-752. (Pubitemid 46527617)
29. Chruszcz M, Chapman MD, Vailes LD, Stura EA, Saint-Remy JM, Minor W et al. Crystal structures of mite allergens Der f 1 and Der p 1 reveal differences in surface-exposed residues that may influence antibody binding. J Mol Biol 2009; 386: 520-530.
30. Skov LK, Seppälä U, Coen JJ, Crickmore N, King TP, Monsalve R et al. Structure of recombinant Ves v 2 at 2.0 Angstrom resolution: structural analysis of an allergenic hyaluronidase from wasp venom. Acta Crystallogr D Biol Crystallogr 2006; 62: 595-604.
31. Mueller GA, Smith AM, Chapman MD, Rule GS, Benjamin DC. Hydrogen exchange nuclear magnetic resonance spectroscopy mapping of antibody epitopes on the house dust mite allergen Der p 2. J Biol Chem 2001; 276: 9359-9365.
32. Mirza O, Henriksen A, Ipsen H, Larsen JN, Wissenbach M, Spangfort MD et al. Dominant epitopes and allergic cross-reactivity: complex formation between a Fab fragment of a monoclonal murine IgG antibody and the major allergen from birch pollen Bet v 1. J Immunol 2000; 165: 331-338. (Pubitemid 30429524)
33. Flicker S, Steinberger P, Ball T, Krauth MT, Verdino P, Valent P et al. Spatial clustering of the IgE epitopes on the major timothy grass pollen allergen Phl p 1: importance for allergenic activity. J Allergy Clin Immunol 2006; 117: 1336-1343.
34. Bernard H, Drumare MF, Guillon B, Paty E, Scheinmann P, Wal JM. Immunochemical characterisation of structure and allergenicity of peanut 2S albumins using different formats of immunoassays. Anal Bioanal Chem 2009; 395: 139-146.
35. Smith-Gill SJ, Lavoie TB, Mainhart CR. Antigenic regions defined by monoclonal antibodies correspond to structural domains of avian lysozyme. J Immunol 1984; 133: 384-393. (Pubitemid 14082063)
36. Suphioglu C, Schappi G, Kenrick J, Levy D, Davies JM, O'Hehir RE. A novel grass pollen allergen mimotope identified by phage display peptide library inhibits allergen-human IgE antibody interaction. FEBS Lett 2001; 502: 46-52. (Pubitemid 32722058)
37. Szalai K, Fuhrmann J, Pavkov T, Scheidl M, Wallmann J, Bramswig KH et al. Mimotopes identify conformational B-cell epitopes on the two major house dust mite allergens Der p 1 and Der p 2. Mol Immunol 2008; 45: 1308-1317. (Pubitemid 350299486)
38. Li M, Gustchina A, Alexandratos J, Wlodawer A, Wunschmann S, Kepley CL et al. Crystal structure of a dimerized cockroach allergen Bla g 2 complexed with a monoclonal antibody. J Biol Chem 2008; 283: 22806-22814.
39. Mueller GA, Edwards LL, Aloor JJ, Fessler MB, Glesner J, Pomes A et al. The structure of the dust mite allergen Der p 7 reveals similarities to innate immune proteins. J Allergy Clin Immunol 2010; 125: 909-917.
40. Kelley LA, Sternberg MJ. Protein structure prediction on the Web: a case study using the Phyre server. Nat Protoc 2009; 4: 363-371.
41. Morris AL, MacArthur MW, Hutchinson EG, Thornton JM. Stereochemical quality of protein structure coordinates. Proteins 1992; 12: 345-364.
42. Laskowski RA, MacArthur MW, Moss DS, Thornton JM. PROCHECK: a program to check the stereochemical quality of protein structures. J Appl Cryst 1993; 26: 283-291.
43. Jones DT, Swindells MB. Getting the most from psi-BLAST. Trends Biochem Sci 2002; 27: 161-164. (Pubitemid 34219327)