메뉴 건너뛰기




Volumn 149, Issue 3, 2011, Pages 258-263

Mathematical modeling of drug delivery from torus-shaped single-layer devices

Author keywords

Dispersed drug; Mathematical modeling; Moving front; Pseudo steady state approximation; Vaginal ring

Indexed keywords

DISPERSED DRUG; MATHEMATICAL MODELING; MOVING FRONT; PSEUDO-STEADY STATE APPROXIMATIONS; VAGINAL RING;

EID: 79951933683     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2010.10.018     Document Type: Article
Times cited : (30)

References (57)
  • 1
    • 39749124309 scopus 로고    scopus 로고
    • Intravaginal oestrogen and progestin administration: Advantages and disadvantages
    • DOI 10.1016/j.bpobgyn.2007.08.010, PII S1521693407001435
    • E. Cicinelli, Intravaginal oestrogen and progestin administration: advantages and disadvantages, Best Pract. Res. Clin. Obstet. Gynaecol. 22 (2008) 391-405. (Pubitemid 351292331)
    • (2008) Best Practice and Research in Clinical Obstetrics and Gynaecology , vol.22 , Issue.2 , pp. 391-405
    • Cicinelli, E.1
  • 2
    • 14844314490 scopus 로고    scopus 로고
    • The vagina as a route for systemic drug delivery
    • DOI 10.1016/j.jconrel.2004.11.034, PII S0168365904006297
    • A. Hussain, F. Ahsan, The vagina as a route for systemic drug delivery, J. Control. Release 103 (2005) 301-313. (Pubitemid 40342532)
    • (2005) Journal of Controlled Release , vol.103 , Issue.2 , pp. 301-313
    • Hussain, A.1    Ahsan, F.2
  • 3
    • 0034306493 scopus 로고    scopus 로고
    • The scope and potential of vaginal drug delivery
    • K. Vermani, S. Garg, The scope and potential of vaginal drug delivery, PSTT 3 (2000) 359-364.
    • (2000) PSTT , vol.3 , pp. 359-364
    • Vermani, K.1    Garg, S.2
  • 5
    • 0026666036 scopus 로고
    • Controlled release contraceptive devices: A status report
    • A.P. Sam, Controlled release contraceptive devices: a status report, J. Control. Release 22 (1992) 35-46.
    • (1992) J. Control. Release , vol.22 , pp. 35-46
    • Sam, A.P.1
  • 6
    • 33645776260 scopus 로고    scopus 로고
    • Drug delivery systems for hormone therapy
    • J. Yoo, C.H. Lee, Drug delivery systems for hormone therapy, J. Control. Release 112 (2006) 1-14.
    • (2006) J. Control. Release , vol.112 , pp. 1-14
    • Yoo, J.1    Lee, C.H.2
  • 7
    • 32044459912 scopus 로고    scopus 로고
    • Contraception: An international perspective
    • DOI 10.1016/j.contraception.2005.08.019, PII S0010782405003264
    • R. Sitruk-Ware, Contraception: an international perspective, Contraception 73 (2006) 215-222. (Pubitemid 43202169)
    • (2006) Contraception , vol.73 , Issue.3 , pp. 215-222
    • Sitruk-Ware, R.1
  • 8
    • 0036017241 scopus 로고    scopus 로고
    • A dynamic mechanical method for determining the silicone elastomer solubility of drugs and pharmaceutical excipients in silicone intravaginal drug delivery rings
    • DOI 10.1016/S0142-9612(02)00086-8, PII S0142961202000868
    • R.K. Malcolm, S. McCullagh, A.D. Woolfson, M. Catney, P. Tallon, A dynamic mechanical method for determining the silicone elastomer solubility of drug and pharmaceutical excipients in silicone intravaginal drug delivery rings, Biomaterials 23 (2002) 3589-3594. (Pubitemid 34626563)
    • (2002) Biomaterials , vol.23 , Issue.17 , pp. 3589-3594
    • Malcolm, R.K.1    McCullagh, S.2    David, W.A.3    Catney, M.4    Tallon, P.5
  • 9
    • 0042156955 scopus 로고    scopus 로고
    • In vitro release of nonoxynol-9 from silicone matrix intravaginal rings
    • R.K. Malcolm, A.D. Woolfson, J. Russell, C. Andrews, In vitro release of nonoxynol-9 from silicone matrix intravaginal rings, J. Control. Release 91 (2003) 355-364.
    • (2003) J. Control. Release , vol.91 , pp. 355-364
    • Malcolm, R.K.1    Woolfson, A.D.2    Russell, J.3    Andrews, C.4
  • 10
    • 0034617373 scopus 로고    scopus 로고
    • High-performance liquid chromatographic determination of 17β-estradiol and 17β-estradiol-3-acetate solubilities and diffusion coefficients in silicone elastomeric intravaginal rings
    • DOI 10.1016/S0378-4347(00)00248-6, PII S0378434700002486
    • J.A. Russell, R.K. Malcolm, K. Campbell, A.D. Woolfson, High-performance liquid chromatographic determination of 17β-estradiol and 17β-estradiol-3-acetate solubilities and diffusion coefficients in silicone elastomeric intravaginal rings, J. Chromatogr. B 744 (2000) 157-163. (Pubitemid 30412061)
    • (2000) Journal of Chromatography B: Biomedical Sciences and Applications , vol.744 , Issue.1 , pp. 157-163
    • Russell, J.A.1    Malcolm, R.K.2    Campbell, K.3    Woolfson, A.D.4
  • 11
    • 0043158878 scopus 로고    scopus 로고
    • Design of a silicone reservoir intravaginal ring for the delivery of oxybutynin
    • DOI 10.1016/S0168-3659(03)00277-3
    • A.D. Woolfson, R.K. Malcolm, R.J. Gallagher, Design of a silicone reservoir intravaginal ring for the delivery of oxybutynin, J. Control. Release 91 (2003) 465-476. (Pubitemid 36976773)
    • (2003) Journal of Controlled Release , vol.91 , Issue.3 , pp. 465-476
    • Woolfson, A.D.1    Malcolm, R.K.2    Gallagher, R.J.3
  • 12
    • 0032827796 scopus 로고    scopus 로고
    • Design of an intravaginal ring for the controlled delivery of 17β-estradiol as its 3-acetate ester
    • DOI 10.1016/S0168-3659(99)00148-0, PII S0168365999001480
    • A.D. Woolfson, G.R.E. Elliott, C.A. Gilligan, C.M. Passmore, Design of an intravaginal ring for the controlled delivery of 17β-estradiol as its 3-acetate ester, J. Control. Release 61 (1999) 319-328. (Pubitemid 29413026)
    • (1999) Journal of Controlled Release , vol.61 , Issue.3 , pp. 319-328
    • Woolfson, A.D.1    Elliott, G.R.E.2    Gilligan, C.A.3    Passmore, C.M.4
  • 13
    • 0017879101 scopus 로고
    • Fabrication and testing of vaginal contraceptive devices designed for release of prespecified dose levels of steroids
    • F.G. Burton, W.E. Skiens, N.R. Gordon, J.T. Veal, D.R. Kalkwarf, G.W. Duncan, Fabrication and testing of vaginal contraceptive devices designed for release of prespecified dose levels of steroids, Contraception 17 (1978) 221-230. (Pubitemid 8299765)
    • (1978) Contraception , vol.17 , Issue.3 , pp. 221-230
    • Burton, F.G.1    Skiens, W.E.2    Gordon, N.R.3
  • 14
    • 0019868275 scopus 로고
    • Levonorgestrel and estradiol release from an improved contraceptive vaginal ring
    • T.M. Jackanicz, Levonorgestrel and estradiol release from an improved contraceptive vaginal ring, Contraception 24 (1981) 323-339. (Pubitemid 12239506)
    • (1981) Contraception , vol.24 , Issue.4 , pp. 323-339
    • Jackanicz, T.M.1
  • 15
    • 0015429604 scopus 로고
    • Release of progesterone from polyethylene devices in vitro and in experimental animals
    • D.R. Kalkwarf, M.R. Sikov, L. Smith, R. Gordon, Release of progesterone from polyethylene devices in vitro and in experimental animals, Contraception 6 (1972) 423-431.
    • (1972) Contraception , vol.6 , pp. 423-431
    • Kalkwarf, D.R.1    Sikov, M.R.2    Smith, L.3    Gordon, R.4
  • 16
    • 0026576741 scopus 로고
    • Progesterone-releasing vaginal rings for use in postpartum contraception. I. In vitro release rates of progesterone from coreloaded rings
    • S.A. Matlin, A. Belenguer, P.E. Hall, Progesterone-releasing vaginal rings for use in postpartum contraception. I. In vitro release rates of progesterone from coreloaded rings, Contraception 45 (1992) 329-341.
    • (1992) Contraception , vol.45 , pp. 329-341
    • Matlin, S.A.1    Belenguer, A.2    Hall, P.E.3
  • 17
    • 0015981018 scopus 로고
    • Controlled drug release from polymeric devices. I. Technique for rapid in vitro release studies
    • Y.W. Chien, H.J. Lambert, D.E. Grant, Controlled drug release from polymeric devices. I. Technique for rapid in vitro release studies, J. Pharm. Sci. 63 (1974) 365-369.
    • (1974) J. Pharm. Sci. , vol.63 , pp. 365-369
    • Chien, Y.W.1    Lambert, H.J.2    Grant, D.E.3
  • 18
    • 0037504004 scopus 로고    scopus 로고
    • Influence of silicone elastomer solubility and diffusivity on the in vitro release of drugs from intravaginal rings
    • DOI 10.1016/S0168-3659(03)00178-0
    • K. Malcolm, D. Woolfson, J. Russell, P. Tallon, L. McAuley, D. Craig, Influence of silicone elastomer solubility and diffusivity on the in vitro release of drugs from intravaginal rings, J. Control. Release 90 (2003) 217-225. (Pubitemid 36694965)
    • (2003) Journal of Controlled Release , vol.90 , Issue.2 , pp. 217-225
    • Malcolm, K.1    Woolfson, D.2    Russell, J.3    Tallon, P.4    McAuley, L.5    Craig, D.6
  • 19
    • 0037203657 scopus 로고    scopus 로고
    • In vitro release properties of etonogestrel and ethinyl estradiol from a contraceptive vaginal ring
    • J.A.H. Van Laarhoven, M.A.B. Kruft, H. Vromans, In vitro release properties of etonogestrel and ethinyl estradiol from a contraceptive vaginal ring, Int. J. Pharm. 232 (2002) 163-173.
    • (2002) Int. J. Pharm. , vol.232 , pp. 163-173
    • Van Laarhoven, J.A.H.1    Kruft, M.A.B.2    Vromans, H.3
  • 20
    • 44049105223 scopus 로고    scopus 로고
    • Review of the combined contraceptive vaginal ring, NuvaRing®
    • F.J.M.E. Roumen, Review of the combined contraceptive vaginal ring, NuvaRing®, Ther. Clin. Risk Manage. 4 (2008) 441-451.
    • (2008) Ther. Clin. Risk Manage. , vol.4 , pp. 441-451
    • Roumen, F.J.M.E.1
  • 21
    • 0035029575 scopus 로고    scopus 로고
    • Use of the novel combined contraceptive vaginal ring NuvaRing for ovulation inhibition
    • T.M.T. Mulders, T.O.M. Dieben, Use of the novel combined contraceptive vaginal ring NuvaRing for ovulation inhibition, Fertil. Steril. 75 (2001) 865-870.
    • (2001) Fertil. Steril. , vol.75 , pp. 865-870
    • Mulders, T.M.T.1    Dieben, T.O.M.2
  • 22
    • 1942423255 scopus 로고    scopus 로고
    • The combined contraceptive vaginal ring (NuvaRing®) and lipid metabolism: A comparative study
    • DOI 10.1016/j.contraception.2004.01.004, PII S0010782404000241
    • M. Tuppurainen, R. Klimscheffskij, M. Venhola, T.O.M. Dieben, The combined contraceptive vaginal ring (NuvaRing®) and lipid metabolism: a comparative study, Contraception 69 (2004) 389-394. (Pubitemid 38510329)
    • (2004) Contraception , vol.69 , Issue.5 , pp. 389-394
    • Tuppurainen, M.1    Klimscheffskij, R.2    Venhola, M.3    Dieben, Th.O.M.4
  • 23
    • 0037369681 scopus 로고    scopus 로고
    • The combined contraceptive vaginal ring, NuvaRing®: An international study of user acceptability
    • A. Novak, C. de la Loge, L. Abetz, E.A. Van der Meulen, The combined contraceptive vaginal ring, NuvaRing®: an international study of user acceptability, Contraception 67 (2003) 187-194.
    • (2003) Contraception , vol.67 , pp. 187-194
    • Novak, A.1    De La Loge, C.2    Abetz, L.3    Van Der Meulen, E.A.4
  • 24
    • 23644446491 scopus 로고    scopus 로고
    • Comparison of ethinylestradiol pharmacokinetics in three hormonal contraceptive formulations: The vaginal ring, the transdermal patch and an oral contraceptive
    • DOI 10.1016/j.contraception.2005.03.005, PII S0010782405000971
    • M.W. Van den Heuvel, A.J.M. Van Bragt, A.K.M. Alnabawy, M.C.J. Kaptein, Comparison of ethinylestradiol pharmacokinetics in three hormonal contraceptive formulations: the vaginal ring, the transdermal patch and an oral contraceptive, Contraception 72 (2005) 168-174. (Pubitemid 41133355)
    • (2005) Contraception , vol.72 , Issue.3 , pp. 168-174
    • Van, D.H.M.W.1    Van, B.A.J.M.2    Alnabawy, A.K.M.3    Kaptein, M.C.J.4
  • 26
    • 0035135987 scopus 로고    scopus 로고
    • Vaginal ring hormone delivery systems in contraception and menopause
    • DOI 10.1097/00003081-200103000-00014
    • S.A. Ballagh, Vaginal ring hormone delivery systems in contraception and menopause, Clin. Obstet. Gynecol. 44 (2001) 106-113. (Pubitemid 32156087)
    • (2001) Clinical Obstetrics and Gynecology , vol.44 , Issue.1 , pp. 106-113
    • Ballagh, S.A.1
  • 27
    • 0035103518 scopus 로고    scopus 로고
    • Efficacy, tolerability and acceptability of a novel contraceptive vaginal ring releasing etonogestrel and ethinyl oestradiol
    • F.J.M.E. Roumen, D. Apter, T.M.T. Mulders, T.O.M. Dieben, Efficacy, tolerability and acceptability of a novel contraceptive vaginal ring releasing etonogestrel and ethinyl oestradiol, Hum. Reprod. 16 (2001) 469-475. (Pubitemid 32218795)
    • (2001) Human Reproduction , vol.16 , Issue.3 , pp. 469-475
    • Roumen, F.J.M.E.1    Apter, D.2    Mulders, T.M.T.3    Dieben, T.O.M.4
  • 28
    • 0036709915 scopus 로고    scopus 로고
    • Efficacy, cycle control, and user acceptability of a novel combined contraceptive vaginal ring
    • DOI 10.1016/S0029-7844(02)02124-5, PII S0029784402021245
    • T.O.M. Dieben, F.J.M.E. Roumen, D. Apter, Efficacy, cycle control and user acceptability of a novel combined contraceptive vaginal ring, Obstet. Gynecol. 100 (2002) 585-593. (Pubitemid 35246150)
    • (2002) Obstetrics and Gynecology , vol.100 , Issue.3 , pp. 585-593
    • Dieben, T.O.M.1    Roumen, F.J.M.E.2    Apter, D.3
  • 29
    • 27744558969 scopus 로고    scopus 로고
    • Controlled release from triple layer, donut-shaped tablets with enteric polymers
    • C. Kim, Controlled release from triple layer, donut-shaped tablets with enteric polymers, AAPS Pharm. Sci. Tech. 6 (2005) E429-E436.
    • (2005) AAPS Pharm. Sci. Tech. , vol.6
    • Kim, C.1
  • 30
    • 41749115005 scopus 로고    scopus 로고
    • Mathematical model to predict drug release, including the early-time burst effect, from swellable homogeneous hydrogels
    • L. Wu, C.S. Brazel, Mathematical model to predict drug release, including the early-time burst effect, from swellable homogeneous hydrogels, Ind. Eng. Chem. Res. 47 (2008) 1518-1526.
    • (2008) Ind. Eng. Chem. Res. , vol.47 , pp. 1518-1526
    • Wu, L.1    Brazel, C.S.2
  • 31
    • 0035850221 scopus 로고    scopus 로고
    • On the importance and mechanisms of burst release in matrix-controlled drug delivery systems
    • DOI 10.1016/S0168-3659(01)00248-6, PII S0168365901002486
    • X. Huang, C.S. Brazel, On the importance and mechanisms of burst release in matrix-controlled drug delivery systems, J. Control. Release 73 (2001) 121-136. (Pubitemid 32539245)
    • (2001) Journal of Controlled Release , vol.73 , Issue.2-3 , pp. 121-136
    • Huang, X.1    Brazel, C.S.2
  • 32
    • 44649126048 scopus 로고    scopus 로고
    • A novel mathematical model quantifying drug release fromlipid implants
    • F. Siepmann, S. Herrmann, G. Winter, J. Siepmann, A novel mathematical model quantifying drug release fromlipid implants, J. Control. Release 128 (2008) 233-240.
    • (2008) J. Control. Release , vol.128 , pp. 233-240
    • Siepmann, F.1    Herrmann, S.2    Winter, G.3    Siepmann, J.4
  • 33
    • 33751183754 scopus 로고    scopus 로고
    • Mathematical modeling and simulation of drug release from microspheres: Implications to drug delivery systems
    • D.Y. Arifin, L.Y. Lee, C.H. Wang, Mathematical modeling and simulation of drug release from microspheres: implications to drug delivery systems, Adv. Drug Deliv. Rev. 58 (2006) 1274-1325.
    • (2006) Adv. Drug Deliv. Rev. , vol.58 , pp. 1274-1325
    • Arifin, D.Y.1    Lee, L.Y.2    Wang, C.H.3
  • 34
    • 0842265899 scopus 로고    scopus 로고
    • Theoretical analysis of the release of slowly dissolving drugs from spherical matrix systems
    • DOI 10.1016/j.jconrel.2003.11.010
    • G. Frenning, Theoretical analysis of the release of slowly dissolving drug from spherical matrix systems, J. Control. Release 95 (2004) 109-117. (Pubitemid 38167685)
    • (2004) Journal of Controlled Release , vol.95 , Issue.1 , pp. 109-117
    • Frenning, G.1
  • 35
    • 73049134701 scopus 로고
    • Rate of release of medicaments from ointment bases containing drug in suspension
    • T. Higuchi, Rate of release of medicaments from ointment bases containing drug in suspension, J. Pharm. Sci. 50 (1961) 874-875.
    • (1961) J. Pharm. Sci. , vol.50 , pp. 874-875
    • Higuchi, T.1
  • 36
    • 0344893332 scopus 로고
    • Mechanism of sustained-action medication
    • T. Higuchi, Mechanism of sustained-action medication, J. Pharm. Sci. 52 (1963) 1145-1149.
    • (1963) J. Pharm. Sci. , vol.52 , pp. 1145-1149
    • Higuchi, T.1
  • 37
    • 0014748052 scopus 로고
    • Release of medroxyprogesterone acetate from a silicone polymer
    • T.J. Roseman, W.I. Higuchi, Release of medroxyprogesterone acetate from a silicone polymer, J. Pharm. Sci. 59 (1970) 353-357.
    • (1970) J. Pharm. Sci. , vol.59 , pp. 353-357
    • Roseman, T.J.1    Higuchi, W.I.2
  • 38
    • 0021796966 scopus 로고
    • Intrinsic release rate from matrix-type drug delivery systems
    • K. Tojo, Intrinsic release rate from matrix-type drug delivery systems, J. Pharm. Sci. 74 (1985) 685-687.
    • (1985) J. Pharm. Sci. , vol.74 , pp. 685-687
    • Tojo, K.1
  • 39
    • 0037038306 scopus 로고    scopus 로고
    • Theoretical analyses of dispersed-drug release from planar matrices with a boundary layer in a finite medium
    • DOI 10.1016/S0168-3659(02)00263-8, PII S0168365902002638
    • Y. Zhou, X.Y. Wu, Theoretical analyses of dispersed-drug release from planar matrices with a boundary layer in a finite medium, J. Control. Release 84 (2002) 1-13. (Pubitemid 35223409)
    • (2002) Journal of Controlled Release , vol.84 , Issue.1-2 , pp. 1-13
    • Zhou, Y.1    Wu, X.Y.2
  • 40
    • 77149125948 scopus 로고    scopus 로고
    • Modeling of drug delivery from erodible and non-erodible laminated planar devices into a finite external medium
    • I.M. Helbling, J.C.D. Ibarra, J.A. Luna, M.I. Cabrera, R.J.A. Grau, Modeling of drug delivery from erodible and non-erodible laminated planar devices into a finite external medium, J. Memb. Sci. 350 (2010) 10-18.
    • (2010) J. Memb. Sci. , vol.350 , pp. 10-18
    • Helbling, I.M.1    Ibarra, J.C.D.2    Luna, J.A.3    Cabrera, M.I.4    Grau, R.J.A.5
  • 41
    • 0026665698 scopus 로고
    • Modeling of the kinetics of drug release from a binary system
    • K.M. Marentette, A.E. Grosser, Modeling of the kinetics of drug release from a binary system, J. Pharm. Sci. 81 (1992) 318-320.
    • (1992) J. Pharm. Sci. , vol.81 , pp. 318-320
    • Marentette, K.M.1    Grosser, A.E.2
  • 42
    • 0015261824 scopus 로고
    • Release of steroids froma silicone polymer
    • T.J. Roseman, Release of steroids froma silicone polymer, J. Pharm. Sci. 61 (1972) 46-50.
    • (1972) J. Pharm. Sci. , vol.61 , pp. 46-50
    • Roseman, T.J.1
  • 43
    • 0038399829 scopus 로고    scopus 로고
    • Modeling and analysis of dispersed-drug release into a finite medium from sphere ensembles with a boundary layer
    • DOI 10.1016/S0168-3659(03)00128-7
    • Y. Zhou, X.Y. Wu, Modeling and analysis of dispersed-drug release into a finite medium from sphere ensembles with a boundary layer, J. Control. Release 90 (2003) 23-36. (Pubitemid 36588876)
    • (2003) Journal of Controlled Release , vol.90 , Issue.1 , pp. 23-36
    • Zhou, Y.1    Wu, X.Y.2
  • 44
    • 55849092853 scopus 로고    scopus 로고
    • Mathematical modeling of drug delivery
    • J. Siepmann, F. Siepmann, Mathematical modeling of drug delivery, Int. J. Pharm. 364 (2008) 328-343.
    • (2008) Int. J. Pharm. , vol.364 , pp. 328-343
    • Siepmann, J.1    Siepmann, F.2
  • 45
    • 0035844746 scopus 로고    scopus 로고
    • Mathematical modeling of bioerodible, polymeric drug delivery systems
    • J. Siepmann, A. Göpferich, Mathematical modeling of bioerodible, polymeric drug delivery systems, Adv. Drug Deliv. Rev. 48 (2001) 229-247.
    • (2001) Adv. Drug Deliv. Rev. , vol.48 , pp. 229-247
    • Siepmann, J.1    Göpferich, A.2
  • 46
    • 0037273037 scopus 로고    scopus 로고
    • Evaluation of mathematical models describing drug release from estradiol transdermal systems
    • DOI 10.1081/DDC-120016687
    • P. Costa, J.M. Sousa Lobo, Evaluation ofmathematicalmodels describing dug release from estradiol transdermal systems, Drug Dev. Ind. Pharm. 29 (2003) 89-97. (Pubitemid 36205885)
    • (2003) Drug Development and Industrial Pharmacy , vol.29 , Issue.1 , pp. 89-97
    • Costa, P.1    Sousa, L.J.M.2
  • 47
    • 0003973615 scopus 로고
    • John Wiley & Sons Inc, New York
    • M.N. Özisik, Heat Conduction, John Wiley & Sons Inc, New York, 1980.
    • (1980) Heat Conduction
    • Özisik, M.N.1
  • 49
    • 84979765962 scopus 로고
    • Ueber diffusion
    • A. Fick, Ueber diffusion, Ann. Phys. 170 (1855) 59-86.
    • (1855) Ann. Phys. , vol.170 , pp. 59-86
    • Fick, A.1
  • 50
    • 0002859110 scopus 로고
    • Fundamentals of controlled-release drug administration
    • (Ed.), J. Swarbrick, Marcel Dekker Inc., New York and Basel
    • Y.W. Chien, Fundamentals of controlled-release drug administration, in: Novel Drug Delivery System (Ed.), J. Swarbrick, Marcel Dekker Inc., New York and Basel, 1982, pp. 465-574.
    • (1982) Novel Drug Delivery System , pp. 465-574
    • Chien, Y.W.1
  • 51
    • 0031723063 scopus 로고    scopus 로고
    • Evaluation and comparison of dissolution data derived from different modified release dosage forms: An alternative method
    • DOI 10.1016/S0168-3659(98)00022-4, PII S0168365998000224
    • V. Pillay, R. Fassihi, Evaluation and comparison of dissolution data derived from different modified release dosage forms: an alternative method, J. Control. Release 55 (1998) 45-55. (Pubitemid 28477563)
    • (1998) Journal of Controlled Release , vol.55 , Issue.1 , pp. 45-55
    • Pillay, V.1    Fassihi, R.2
  • 52
    • 0035073301 scopus 로고    scopus 로고
    • Modeling and comparison of dissolution profiles
    • DOI 10.1016/S0928-0987(01)00095-1, PII S0928098701000951
    • P. Costa, J.M. Sousa Lobo, Modeling and comparison of dissolution profiles, Eur. J. Pharm. Sci. 13 (2001) 123-133. (Pubitemid 32288781)
    • (2001) European Journal of Pharmaceutical Sciences , vol.13 , Issue.2 , pp. 123-133
    • Costa, P.1    Sousa, L.J.M.2
  • 53
    • 2342652446 scopus 로고    scopus 로고
    • Mathematical comparison of dissolution profiles
    • J.W. Moore, H.H. Flanner, Mathematical comparison of dissolution profiles, Pharm. Tech. 20 (1996) 64-74.
    • (1996) Pharm. Tech. , vol.20 , pp. 64-74
    • Moore, J.W.1    Flanner, H.H.2
  • 57


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.