High-performance liquid chromatographic determination of 17β-estradiol and 17β-estradiol-3-acetate solubilities and diffusion coefficients in silicone elastomeric intravaginal rings

Journal of Chromatography B: Biomedical Sciences and Applications

Volumn 744, Issue 1, 2000, Pages 157-163

  Russell, Julie A ^a   Malcolm, R Karl ^a   Campbell, Katrina ^a   Woolfson, A David ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

17 Estradiol; 17 Estradiol 3 acetate; Silicone

Indexed keywords

BENZALKONIUM CHLORIDE; ESTRADIOL; ESTRADIOL DERIVATIVE; PRODRUG; SILASTIC;

ARTICLE; DIFFUSION COEFFICIENT; DRUG DETERMINATION; DRUG RELEASE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ADMINISTRATION, INTRAVAGINAL; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIFFUSION; ELASTOMERS; ESTRADIOL; HORMONE REPLACEMENT THERAPY; HYDROLYSIS; SILICONES; SOLUBILITY;

EID: 0034617373     PISSN: 13872273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4347(00)00248-6     Document Type: Article

References (16)

1. Williams C.L., Stancel G.M. Hardman J.G., Goodman Gilman A., Limbird L.E. Goodman and Gilman's The Pharmacological Basis of Therapeutics. 1996;1412 McGraw-Hill, New York.
2. Belchetz P.E. New Engl. J. Med. 330:1994;1062-1071.
3. Jewelewicz R. Fertil. Steril. 67:1997;1-12.
4. Session D.R., Kelly A.C., Jewelewicz R. Intern. J. Fertil. 38:1993;277-284.
5. Grady D., Rubin S.M., Petitti D.B., Fox C.S., Black D., Ettinger B., Ernster V.L., Cummings S.R. Ann. Intern. Med. 117:1992;1016-1037.
6. Smith P., Heimer G., Lindskog M., Ulmsten U. Maturitas. 16:1993;145-154.
7. Barentsen R., van de Weijer P.H.M., Schram J.H.N. Eur. J. Obstet. Gynaecol. 71:1997;73-80.
8. Englund D.E., Victor A., Johansson E.D.B. Maturitas. 3:1981;125-133.
9. Nash H.A., Brache V., Alvarez-Sanchez F., Jackanicz T.M., Harmon T.M. Maturitas. 26:1997;27-33.
10. Vartiainen J., Wahlstrom T., Nilsson C.G. Maturitas. 17:1993;129-137.
11. Woolfson A.D., Elliott G.R.E., Gilligan C.A., Passmore C.M. J. Control. Rel. 61:1999;319-328.
12. Lamparczyk H., Zarzycki P.K., Nowakowska J., Ochocka R.J. Chromatographia. 38:1994;168-172.
13. Yamada K., Tojo K. Eur. J. Pharmaceut. Biopharmaceut. 43:1997;253-258.
14. Terada H., Yamamoto K., Miyabe M. Jap. J. Toxicol. Environm. Health. 38:1992;537-544.
15. Chien Y.W. Novel Drug Delivery Systems. 1992;Marcel Dekker, New York. Chapter 2.
16. Chien Y.W. Chem. Pharm. Bull. 24:1976;1471.