-
1
-
-
0030614703
-
Review: Quantitative studies of the risk of serious hepatic injury in persons using nonsteroidal antiinflammatory drugs
-
DOI 10.1002/art.1780400204
-
Walker, A. M. Quantitative studies of the risk of serious hepatic injury in person using nonsteroidal antiinflammatory drugs. Arthritis Rheum 40:201-208 (1997). (Pubitemid 27114083)
-
(1997)
Arthritis and Rheumatism
, vol.40
, Issue.2
, pp. 201-208
-
-
Walker, A.M.1
-
3
-
-
0032476571
-
Nonsteroidal anti-inflammatory drug-associated toxicity of the liver, lower gastrointestinal tract, and esophagus
-
DOI 10.1016/S0002-9343(98)00276-9, PII S0002934398002769
-
Bjorkman, D. Nonsteroidal anti-inflammatory drugassociated toxicity of the liver, lower gastrointestinal tract, and esophagus. Am J Med 105:17S-21S (1998). (Pubitemid 28553711)
-
(1998)
American Journal of Medicine
, vol.105
, Issue.5 A
-
-
Bjorkman, D.1
-
4
-
-
0242551672
-
Hepatocellular damage from non-steroidal anti-inflammatory drugs
-
DOI 10.1093/qjmed/hcg138
-
O'Connor, N., Dargan, P. I. & Jones, A. L. Hepatocellular damage from non-steroidal anti-inflammatory drugs. Q J Med 96:787-791 (2003). (Pubitemid 37369293)
-
(2003)
QJM - Monthly Journal of the Association of Physicians
, vol.96
, Issue.11
, pp. 787-791
-
-
O'Connor, N.1
Dargan, P.I.2
Jones, A.L.3
-
7
-
-
0036242256
-
Role of CCR2 in macrophage migration into the liver during acetaminophen-induced hepatotoxicity in the mouse
-
DOI 10.1053/jhep.2002.33162
-
Dambach, D. M. et al. Role of CCR2 in macrophage migration into the liver during acetaminophen-induced hepatotoxicity in the mouse. Hepatology 35:1093-1103 (2002). (Pubitemid 34454006)
-
(2002)
Hepatology
, vol.35
, Issue.5
, pp. 1093-1103
-
-
Dambach, D.M.1
Watson, L.M.2
Gray, K.R.3
Durham, S.K.4
Laskin, D.L.5
-
8
-
-
37149025669
-
Prediction of a carcinogenic potential of rat hepatocariconogens using toxicogenomics analysis of short-term in vivo studies
-
Heidrun, E. Z. et al. Prediction of a carcinogenic potential of rat hepatocariconogens using toxicogenomics analysis of short-term in vivo studies. Mutat Res 637:23-39 (2008).
-
(2008)
Mutat. Res.
, vol.637
, pp. 23-39
-
-
Heidrun, E.Z.1
-
9
-
-
34047177929
-
Biomarker qualification pilot process at the US food and drug administration
-
Goodsaid, F. & Frueh, F. Biomarker qualification pilot process at the US Food and Drug Administration. AAPS J 9: E105-E108 (2007).
-
(2007)
AAPS J.
, vol.9
-
-
Goodsaid, F.1
Frueh, F.2
-
10
-
-
0034825987
-
The use of genomics technology
-
Harries, H. M. et al. The use of genomics technology. Toxicol In Vitro 15:399-405 (2001).
-
(2001)
Toxicol. In Vitro
, vol.15
, pp. 399-405
-
-
Harries, H.M.1
-
11
-
-
34548168341
-
Nonsteroidal anti-inflammatory drug-induced hepato-toxicity
-
Aithal, G. P. & Day, C. P. Nonsteroidal anti-inflammatory drug-induced hepato-toxicity. Clin Liver Dis 11:563-575 (2007).
-
(2007)
Clin. Liver Dis.
, vol.11
, pp. 563-575
-
-
Aithal, G.P.1
Day, C.P.2
-
12
-
-
0036251569
-
Hepatotoxicity of commonly used drugs: Nonsteroidal anti-inflammatory drugs, antihypertensives, antidiabetic agents, anticonvulsants, lipid-lowering agents, psychotropic drugs
-
DOI 10.1055/s-2002-30102
-
Chitturi, S. & George, J. Hepatotoxicity of commonly used drugs: Nonsteroidal anti-inflammatory drugs, antihypertensives, antidiabetic agents, anticonvulsants, lipid-lowering agents, psychotropic drugs. Semin Liver Dis 22:169-183 (2002). (Pubitemid 34496470)
-
(2002)
Seminars in Liver Disease
, vol.22
, Issue.2
, pp. 169-183
-
-
Chitturi, S.1
George, J.2
-
13
-
-
2942585269
-
Modelling in vitro hepatotoxicity using molecular interaction fields and SIMCA
-
DOI 10.1016/j.jmgm.2004.03.009, PII S1093326304000245, Bioactive Discovery in the New Millennium
-
Clark, R. D. et al. Modelling in vitro hepatotoxicity using molecular interaction fields and SIMCA. J Mol Graph Model 22:487-497 (2004). (Pubitemid 38746574)
-
(2004)
Journal of Molecular Graphics and Modelling
, vol.22
, Issue.6
, pp. 487-497
-
-
Clark, R.D.1
Wolohan, P.R.N.2
Hodgkin, E.E.3
Kelly, J.H.4
Sussman, N.L.5
-
14
-
-
0032919364
-
KEGG: Kyoto encyclopedia of genes and genomes
-
DOI 10.1093/nar/27.1.29
-
Ogata, H. et al. KEGG: Kyoto Encyclopedia of genes and genomes. Oxford University Press 27:29-34 (1999). (Pubitemid 29209394)
-
(1999)
Nucleic Acids Research
, vol.27
, Issue.1
, pp. 29-34
-
-
Ogata, H.1
Goto, S.2
Sato, K.3
Fujibuchi, W.4
Bono, H.5
Kanehisa, M.6
-
15
-
-
49349105027
-
Multiendpoint mechanistic profiling of hepatotoxicants in HepG2/C3A human hepatoma cells and novel statistical approaches for development of a prediction model for acute hepatotoxicity
-
Flynn, J. F. & Ferguson, M. S. Multiendpoint mechanistic profiling of hepatotoxicants in HepG2/C3A human hepatoma cells and novel statistical approaches for development of a prediction model for acute hepatotoxicity. Toxicol In Vitro 22:1618-1631 (2008).
-
(2008)
Toxicol. In Vitro
, vol.22
, pp. 1618-1631
-
-
Flynn, J.F.1
Ferguson, M.S.2
-
16
-
-
0037261485
-
Development of a DNA microarray for toxicology based on hepatotoxin-regulated sequences
-
Waring, J. F. et al. Development of a DNA microarray for toxicology based on hepatotoxin-regulated sequences. Toxicogenomics 111:863-870 (2003). (Pubitemid 36701366)
-
(2003)
Environmental Health Perspectives
, vol.111
, Issue.6
, pp. 863-870
-
-
Waring, J.F.1
Cavet, G.2
Jolly, R.A.3
McDowell, J.4
Dai, H.5
Ciurlionis, R.6
Zhang, C.7
Stoughton, R.8
Lum, P.9
Ferguson, A.10
Roberts, C.J.11
Ulrich, R.G.12
-
17
-
-
30144445804
-
Toxicogenomic analysis methods for predictive toxicology
-
DOI 10.1016/j.vascn.2005.05.006, PII S1056871905000730
-
Maggioli, J., Hoover, A. & Weng, L. Toxicogenomic analysis methods for predictive toxicology. J Pharm Toxicol Methods 53:31-37 (2006). (Pubitemid 43052701)
-
(2006)
Journal of Pharmacological and Toxicological Methods
, vol.53
, Issue.1
, pp. 31-37
-
-
Maggioli, J.1
Hoover, A.2
Weng, L.3
-
18
-
-
50149121377
-
Assessing chronic liver toxicity based on relative gene expression data
-
Kulkarni, K., Larsen, P. & Linninger, A. A. Assessing chronic liver toxicity based on relative gene expression data. J Theor Biol 254:308-318 (2008).
-
(2008)
J. Theor. Biol.
, vol.254
, pp. 308-318
-
-
Kulkarni, K.1
Larsen, P.2
Linninger, A.A.3
-
19
-
-
0037249501
-
PANTHER: A browsable database of gene products organized by biological function, using curated protein family and subfamily classification
-
DOI 10.1093/nar/gkg115
-
Thomas, P. D. et al. Panther: a browsable database of gene products organized by biological function, using curated protein family and subfamily classification. Nucleic Acids Res 31:334-341 (2003). (Pubitemid 36150398)
-
(2003)
Nucleic Acids Research
, vol.31
, Issue.1
, pp. 334-341
-
-
Thomas, P.D.1
Kejariwal, A.2
Campbell, M.J.3
Mi, H.4
Diemer, K.5
Guo, N.6
Ladunga, I.7
Ulitsky-Lazareva, B.8
Muruganujan, A.9
Rabkin, S.10
Vandergriff, J.A.11
Doremieux, O.12
-
20
-
-
38849109564
-
Detection of early signals of hepatotoxicity by gene expression profiling studies with cultures of metabolically competent human hepatocytes
-
DOI 10.1007/s00204-007-0234-1
-
Thum, T. & Borlak, J. Detection of early signals of hepatotoxicity by gene expression profiling studies with cultures of metabolically competent human hepatocytes. Arch Toxicol 82:89-101 (2008). (Pubitemid 351187672)
-
(2008)
Archives of Toxicology
, vol.82
, Issue.2
, pp. 89-101
-
-
Thum, T.1
Borlak, J.2
-
21
-
-
38749154690
-
Trovafloxacin-induced gene expression changes in liver-derived in vitro systems: Comparison of primary human hepatocytes to HepG2 cells
-
DOI 10.1124/dmd.107.017608
-
Liguori, M. J., Blomme, E. A. G. & Waring, J. F. Trovafloxacin- induced gene expression changes in liver-derived in vitro systems: comparison of primary human hepatocytes to HepG2 cells. Drug Metab Dispos 36:223-233 (2008). (Pubitemid 351185733)
-
(2008)
Drug Metabolism and Disposition
, vol.36
, Issue.2
, pp. 223-233
-
-
Liguori, M.J.1
Blomme, E.A.G.2
Waring, J.F.3
-
22
-
-
44349170697
-
Microarray analysis in rat liver slices correctly predicts in vivo hepatotoxicity
-
Elferink, M. G. L. et al. Microarray analysis in rat liver slices correctly predicts in vivo hepatotoxicity. Toxicol Appl Pharmacol 229:300-309 (2008).
-
(2008)
Toxicol. Appl. Pharmacol.
, vol.229
, pp. 300-309
-
-
Elferink, M.G.L.1
-
23
-
-
37749045357
-
Development of an in vitro assay for the investigation of metabolism-induced drug hepatotoxicity
-
Otto, M. et al. Development of an in vitro assay for the investigation of metabolism-induced drug hepatotoxicity. Cell Biol Toxicol 24:87-99 (2008).
-
(2008)
Cell. Biol. Toxicol.
, vol.24
, pp. 87-99
-
-
Otto, M.1
-
24
-
-
11244334169
-
Microarray analysis in human hepatocytes suggests a mechanism for hepatotoxicity induced by trovafloxacin
-
DOI 10.1002/hep.20514
-
Liguori, M. J. et al. Microarray analysis in human hepatocytes suggests a mechanism for hepatotoxicity induced by trovafloxacin. Hepatology 41:177-186 (2005). (Pubitemid 40066396)
-
(2005)
Hepatology
, vol.41
, Issue.1
, pp. 177-186
-
-
Liguori, M.J.1
Anderson, M.G.2
Bukofzer, S.3
McKim, J.4
Pregenzer, J.F.5
Retief, J.6
Spear, B.B.7
Waring, J.F.8
-
25
-
-
34250176529
-
Development of an approach for Ab Initio estimation of compound-induced liver injury based on global gene transcriptional profiles
-
Dai, X. et al. Development of an approach for Ab Initio estimation of compound-induced liver injury based on global gene transcriptional profiles. Genome Inform 17:77-88 (2006).
-
(2006)
Genome Inform.
, vol.17
, pp. 77-88
-
-
Dai, X.1
-
26
-
-
40349116296
-
Gene expression profiling of methapyrilene-induced hepatotoxicity in rat
-
DOI 10.2131/jts.33.37
-
Uehara, T. et al. Gene expression profiling of methapyrilene-induced hepatotoxicity in rat. J Toxicol Sci 33:37-50 (2008). (Pubitemid 351340762)
-
(2008)
Journal of Toxicological Sciences
, vol.33
, Issue.1
, pp. 37-50
-
-
Uehara, T.1
Kiyosawa, N.2
Hirode, M.3
Omura, K.4
Shimizu, T.5
Ono, A.6
Mizukawa, Y.7
Miyagishima, T.8
Nagao, T.9
Urushidani, T.10
-
27
-
-
0034518116
-
Toxicogenomics-based discrimination of toxic mechanism in HepG2 human hepatoma cells
-
DOI 10.1093/toxsci/58.2.399
-
Burczynski, M. E. et al. Toxicogenomics-Based discrimination of toxic mechanism in HepG2 human hepatoma cells. J Toxicol Sci 58:399-415 (2000). (Pubitemid 32042437)
-
(2000)
Toxicological Sciences
, vol.58
, Issue.2
, pp. 399-415
-
-
Burczynski, M.E.1
McMillian, M.2
Ciervo, J.3
Li, L.4
Parker, J.B.5
Dunn II, R.T.6
Hicken, S.7
Farr, S.8
Johnson, M.D.9
-
28
-
-
34547914464
-
Acute hepatotoxicity: A predictive model based on focused illumina microarrays
-
DOI 10.1093/toxsci/kfm131
-
Zidek, N. et al. Acute hepatotoxicity: A predictive model based on focused illumina microarray. Toxicol Sci 99:289-302 (2007). (Pubitemid 47250386)
-
(2007)
Toxicological Sciences
, vol.99
, Issue.1
, pp. 289-302
-
-
Zidek, N.1
Hellmann, J.2
Kramer, P.-J.3
Hewitt, P.G.4
-
29
-
-
33748302750
-
Prediction of carcinogenic potential by a toxicogenomic approach using rat hepatoma cells
-
Kazunari, T. et al. Prediction of carcinogenic potential by a toxicogenomic approach using rat hepatoma cells. Cancer Sci 97:1002-1010 (2006).
-
(2006)
Cancer Sci.
, vol.97
, pp. 1002-1010
-
-
Kazunari, T.1
|