Solvent-free synthesis of 1-(hydroxyquinolyl)- and 1-(hydroxyisoquinolyl)- 1,2,3,4-tetrahydroisoquinolines by modified mannich reaction

Synthesis

Volumn , Issue 5, 2011, Pages 745-748

  Szatmári, István ^a   Fülöp, Ferenc ^a  

^a UNIVERSITY OF SZEGED   (Hungary)

Author keywords

bioorganic chemistry; heterocycles; Mannich bases; multicomponent reaction; nucleophilic addition

Indexed keywords

BIOORGANIC CHEMISTRY; HETEROCYCLES; MANNICH BASES; MULTI-COMPONENT REACTIONS; NUCLEOPHILIC ADDITIONS;

ADDITION REACTIONS; BIOCHEMISTRY;

SYNTHESIS (CHEMICAL);

1 (HYDROXYISOQUINOLYL) 1,2,3,4 TETRAHYDROISOQUINOLINE DERIVATIVE; 1 (HYDROXYQUINOLYL) 1,2,3,4 TETRAHYDROISOQUINOLINE DERIVATIVE; 2 METHYL 7 (1,2,3,4 TETRAHYDROISOQUINOLIN 1 YL)QUINOLIN 8 OL; 3 (1,2,3,4 TETRAHYDROISOQUINOLIN 1 YL)QUINOLIN 4 OL; 3 (6,7 DIMETHOXY 1,2,3,4 TETRAHYDROISOQUINOLIN 1 YL)QUINOLIN 4 OL; 4 (1,2,3,4 TETRAHYDROISOQUINOLIN 1 YL)ISOQUINOLIN 3 OL; 4 (6,7 DIMETHOXY 1,2,3,4 TETRAHYDROISOQUINOLIN 1 YL)ISOQUINOLIN 3 OL; 5 (1,2,3,4 TETRAHYDROISOQUINOLIN 1 YL)QUINOLIN 6 OL; 6 (1,2,3,4 TETRAHYDROISOQUINOLIN 1 YL)ISOQUINOLIN 5 OL; 6 (6,7 DIMETHOXY 1,2,3,4 TETRAHYDROISOQUINOLIN 1 YL)ISOQUINOLIN 5 OL; 7 (1,2,3,4 TETRAHYDROISOQUINOLIN 1 YL)QUINOLIN 8 OL; 7 (6,7 DIMETHOXY 1,2,3,4 TETRAHYDROISOQUINOLIN 1 YL)QUINOLIN 8 OL; TETRAHYDROISOQUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; HEATING; MANNICH REACTION; MICROWAVE COOKING; REACTION TIME; SOLVENT FREE SYNTHESIS; SYNTHESIS; TEMPERATURE SENSITIVITY;

EID: 79951855739     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0030-1258423     Document Type: Article

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