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Volumn 5, Issue 4, 2003, Pages 477-479

The Mannich reaction of hydrazones: Improved reactivity under solvent-free conditions

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; AMINE; FORMALDEHYDE; HYDRAZONE DERIVATIVE; NITRO DERIVATIVE; SOLVENT; TOLUENE;

EID: 0242522295     PISSN: 14639262     EISSN: None     Source Type: Journal    
DOI: 10.1039/b306242b     Document Type: Article
Times cited : (16)

References (12)
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  • 2
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    • For some recent examples: (a) V. P. Balema, J. W. Wiench, M. Pruski and V. K. Pecharsky, Chem. Commun., 2002, 724-725; (b) C. J. Li and C. Wei, Chem. Commun., 2002, 268-269; (c) J. Long, J. Hu, X. Shen, B. Ji and K. Ding, J. Am. Chem. Soc, 2002, 124, 10-11; (d) C. Cimarelli, A. Mazzanti, G. Palmieri and E. Volpini, J. Org. Chem., 2001, 66, 4759-4765; (e) A. Hoz, A. Diaz-Ortiz, T. Elguero, L. J. Martinez, A. Moreno and A. Sanchez-Migallon. Tetrahedron, 2001, 57, 4397-4404; (f) J. M. Thomas, R. Raja, G. Sankar, B. F. G. Johnson and D. W. Lewis, Chem. Eur. J., 2001, 7, 2973-2978.
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    • Li, C.J.1    Wei, C.2
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    • note
    • The elimination of N-benzylpiperazine in excess was performed by extraction using an organic solvent; this treatment could be suppressed by the use of more volatile amines (the use of morpholine instead of N-benzylpiperazine affords with hydrazone 1a the corresponding hydrazone in a 57% isolated yield).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.