메뉴 건너뛰기




Volumn 6, Issue 2, 2011, Pages

Investigating the potential role of genetic and epigenetic variation of DNA methyltransferase genes in hyperplastic polyposis syndrome

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; DNA METHYLTRANSFERASE; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; GENE PRODUCT; K RAS PROTEIN; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; PROTEIN DNMT3L; PROTEIN MLH1; PROTEIN WIF1; THYMINE; UNCLASSIFIED DRUG; DNA (CYTOSINE 5) METHYLTRANSFERASE; KRAS PROTEIN, HUMAN; ONCOPROTEIN; RAS PROTEIN;

EID: 79951818061     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0016831     Document Type: Article
Times cited : (9)

References (66)
  • 2
    • 26944443724 scopus 로고    scopus 로고
    • Serrated adenoma of the colorectum and the DNA-methylator phenotype
    • Jass JR, (2000) Serrated adenoma of the colorectum and the DNA-methylator phenotype. Nat Clin Pract Oncol 2 (8): 398-405.
    • (2000) Nat Clin Pract Oncol , vol.2 , Issue.8 , pp. 398-405
    • Jass, J.R.1
  • 3
    • 24144491263 scopus 로고    scopus 로고
    • Serrated polyps of the large intestine: a morphologic and molecular review of an evolving concept
    • Snover DC, Jass JR, Fenoglio-Preiser C, Batts KP, (2005) Serrated polyps of the large intestine: a morphologic and molecular review of an evolving concept. Am J Clin Pathol 124 (3): 380-91.
    • (2005) Am J Clin Pathol , vol.124 , Issue.3 , pp. 380-391
    • Snover, D.C.1    Jass, J.R.2    Fenoglio-Preiser, C.3    Batts, K.P.4
  • 4
    • 30644459835 scopus 로고    scopus 로고
    • Serrated pathway and APC (conventional)-type colorectal polyps: molecular-morphologic correlations, genetic pathways, and implications for classification
    • Goldstein NS, (2006) Serrated pathway and APC (conventional)-type colorectal polyps: molecular-morphologic correlations, genetic pathways, and implications for classification. Am J Clin Pathol 125 (1): 146-53.
    • (2006) Am J Clin Pathol , vol.125 , Issue.1 , pp. 146-153
    • Goldstein, N.S.1
  • 5
    • 33745541234 scopus 로고    scopus 로고
    • CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer
    • Weisenberger DJ, Siegmund KD, Campan M, Young J, Long TI, et al. (2006) CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer. Nat Genet 38 (7): 787-93.
    • (2006) Nat Genet , vol.38 , Issue.7 , pp. 787-793
    • Weisenberger, D.J.1    Siegmund, K.D.2    Campan, M.3    Young, J.4    Long, T.I.5
  • 6
    • 33749182353 scopus 로고    scopus 로고
    • Extensive DNA methylation in normal colorectal mucosa in hyperplastic polyposis
    • Minoo P, Baker K, Goswami R, Chong G, Foulkes WD, et al. (2006) Extensive DNA methylation in normal colorectal mucosa in hyperplastic polyposis. Gut 55 (10): 1467-74.
    • (2006) Gut , vol.55 , Issue.10 , pp. 1467-1474
    • Minoo, P.1    Baker, K.2    Goswami, R.3    Chong, G.4    Foulkes, W.D.5
  • 7
    • 3242686837 scopus 로고    scopus 로고
    • BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum
    • Kambara T, Simms LA, Whitehall VL, Spring KJ, Wynter CV, et al. (2004) BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum. Gut 53 (8): 1137-44.
    • (2004) Gut , vol.53 , Issue.8 , pp. 1137-1144
    • Kambara, T.1    Simms, L.A.2    Whitehall, V.L.3    Spring, K.J.4    Wynter, C.V.5
  • 8
    • 0042941629 scopus 로고    scopus 로고
    • BRAF and KRAS mutations in colorectal hyperplastic polyps and serrated adenomas
    • Chan TL, Zhao W, Leung SY, Yuen ST, (2003) BRAF and KRAS mutations in colorectal hyperplastic polyps and serrated adenomas. Cancer Res 63 (16): 4878-81.
    • (2003) Cancer Res , vol.63 , Issue.16 , pp. 4878-4881
    • Chan, T.L.1    Zhao, W.2    Leung, S.Y.3    Yuen, S.T.4
  • 9
    • 0842278570 scopus 로고    scopus 로고
    • Epigenetic changes in colorectal cancer
    • Kondo Y, Issa JP, (2004) Epigenetic changes in colorectal cancer. Cancer Metastasis Rev 23 (1-2): 29-39.
    • (2004) Cancer Metastasis Rev , vol.23 , Issue.1-2 , pp. 29-39
    • Kondo, Y.1    Issa, J.P.2
  • 10
    • 0036895068 scopus 로고    scopus 로고
    • Characterisation of colorectal cancers showing hypermethylation at multiple CpG islands
    • van Rijnsoever M, Grieu F, Elsaleh H, Joseph D, Iacopetta B, (2002) Characterisation of colorectal cancers showing hypermethylation at multiple CpG islands. Gut 51 (6): 797-802.
    • (2002) Gut , vol.51 , Issue.6 , pp. 797-802
    • van Rijnsoever, M.1    Grieu, F.2    Elsaleh, H.3    Joseph, D.4    Iacopetta, B.5
  • 11
    • 0034681117 scopus 로고    scopus 로고
    • Distinct genetic profiles in colorectal tumors with or without the CpG island methylator phenotype
    • Toyota M, Ohe-Toyota M, Ahuja N, Issa JP, (2000) Distinct genetic profiles in colorectal tumors with or without the CpG island methylator phenotype. Proc Natl Acad Sci 97 (2): 710-5.
    • (2000) Proc Natl Acad Sci , vol.97 , Issue.2 , pp. 710-715
    • Toyota, M.1    Ohe-Toyota, M.2    Ahuja, N.3    Issa, J.P.4
  • 12
    • 16544363110 scopus 로고    scopus 로고
    • Colorectal cancer with mutation in BRAF, KRAS, and wild-type with respect to both oncogenes showing different patterns of DNA methylation
    • Nagasaka T, Sasamoto H, Notohara K, Cullings HM, Takeda M, et al. (2004) Colorectal cancer with mutation in BRAF, KRAS, and wild-type with respect to both oncogenes showing different patterns of DNA methylation. J Clin Oncol 22 (22): 4584-94.
    • (2004) J Clin Oncol , vol.22 , Issue.22 , pp. 4584-4594
    • Nagasaka, T.1    Sasamoto, H.2    Notohara, K.3    Cullings, H.M.4    Takeda, M.5
  • 13
    • 1842529801 scopus 로고    scopus 로고
    • Hyperplastic (serrated) polyps of the colorectum: relationship of CpG island methylator phenotype and K-ras mutation to location and histologic subtype
    • O'Brien MJ, Yang S, Clebanoff JL, Mulcahy E, Farraye FA, et al. (2004) Hyperplastic (serrated) polyps of the colorectum: relationship of CpG island methylator phenotype and K-ras mutation to location and histologic subtype. Am J Surg Pathol 28 (4): 423-34.
    • (2004) Am J Surg Pathol , vol.28 , Issue.4 , pp. 423-434
    • O'Brien, M.J.1    Yang, S.2    Clebanoff, J.L.3    Mulcahy, E.4    Farraye, F.A.5
  • 16
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones PA, Baylin SB, (2002) The fundamental role of epigenetic events in cancer. Nat Rev Genetics 3 (6): 415-428.
    • (2002) Nat Rev Genetics , vol.3 , Issue.6 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 17
    • 33646369393 scopus 로고    scopus 로고
    • Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band
    • Frigola J, Song J, Stirzaker C, Hinshelwood RA, Peinado MA, et al. (2006) Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band. Nature Genetics 38 (5): 540-549.
    • (2006) Nature Genetics , vol.38 , Issue.5 , pp. 540-549
    • Frigola, J.1    Song, J.2    Stirzaker, C.3    Hinshelwood, R.A.4    Peinado, M.A.5
  • 18
    • 0031781179 scopus 로고    scopus 로고
    • GAMETOGENESIS '98: Methylation and the Unequal Developmental Potentials of the Oocyte and Sperm Genomes
    • Bestor TH, (1998) GAMETOGENESIS '98: Methylation and the Unequal Developmental Potentials of the Oocyte and Sperm Genomes. Am J Hum Genet 62: 1269-1273.
    • (1998) Am J Hum Genet , vol.62 , pp. 1269-1273
    • Bestor, T.H.1
  • 19
    • 0032102949 scopus 로고    scopus 로고
    • Dnmt2 is not required for de novo and maintenance methylation of viral DNA in embryonic stem cells
    • Okano M, Xie S, Li E, (1998) Dnmt2 is not required for de novo and maintenance methylation of viral DNA in embryonic stem cells. Nucleic Acid Research 26: 2536-2540.
    • (1998) Nucleic Acid Research , vol.26 , pp. 2536-2540
    • Okano, M.1    Xie, S.2    Li, E.3
  • 20
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • Okano M, Bell DW, Haber DA, Li E, (1999) DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99 (3): 247-57.
    • (1999) Cell , vol.99 , Issue.3 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3    Li, E.4
  • 21
    • 0032769445 scopus 로고    scopus 로고
    • Cloning, expression and chromosome locations of the human DNMT3 gene family
    • Xie S, Wang Z, Okano M, Nogami M, Li Y, et al. (1999) Cloning, expression and chromosome locations of the human DNMT3 gene family. Gene 236 (1): 87-95.
    • (1999) Gene , vol.236 , Issue.1 , pp. 87-95
    • Xie, S.1    Wang, Z.2    Okano, M.3    Nogami, M.4    Li, Y.5
  • 22
    • 18744427037 scopus 로고    scopus 로고
    • Isolation and initial characterization of a novel zinc finger gene, DNMT3L, on 21q22.3, related to the cytosine-5-methyltransferase 3 gene family
    • Aapola U, Kawasaki K, Scott HS, Ollila J, Vihinen M, et al. (2000) Isolation and initial characterization of a novel zinc finger gene, DNMT3L, on 21q22.3, related to the cytosine-5-methyltransferase 3 gene family. Genomics 65 (3): 293-8.
    • (2000) Genomics , vol.65 , Issue.3 , pp. 293-298
    • Aapola, U.1    Kawasaki, K.2    Scott, H.S.3    Ollila, J.4    Vihinen, M.5
  • 23
    • 20144374921 scopus 로고    scopus 로고
    • Meiotic and epigenetic defects in Dnmt3L-knockout mouse spermatogenesis
    • Webster K, O'Bryan MK, Fletcher S, Crewther PE, Aapola U, et al. (2005) Meiotic and epigenetic defects in Dnmt3L-knockout mouse spermatogenesis. PNAS 102 (11): 4068-4073.
    • (2005) PNAS , vol.102 , Issue.11 , pp. 4068-4073
    • Webster, K.1    O'Bryan, M.K.2    Fletcher, S.3    Crewther, P.E.4    Aapola, U.5
  • 24
    • 0020486108 scopus 로고
    • Substrate and sequence specificity of a eukariotic DNA methylase
    • Gruenbaum Y, Cedar H, Razin A, (1982) Substrate and sequence specificity of a eukariotic DNA methylase. Nature 295: 620-22.
    • (1982) Nature , vol.295 , pp. 620-622
    • Gruenbaum, Y.1    Cedar, H.2    Razin, A.3
  • 25
    • 0030006949 scopus 로고    scopus 로고
    • Murine DNA cytosine-C5 methyltransferase: pre-steady- and steady-state kinetic analysis with regulatory DNA sequences
    • Flynn J, Glickman JF, Reich NO, (1996) Murine DNA cytosine-C5 methyltransferase: pre-steady- and steady-state kinetic analysis with regulatory DNA sequences. Biochemistry 35 (23): 7308-15.
    • (1996) Biochemistry , vol.35 , Issue.23 , pp. 7308-7315
    • Flynn, J.1    Glickman, J.F.2    Reich, N.O.3
  • 26
    • 3042584653 scopus 로고    scopus 로고
    • Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting
    • Kaneda M, Okano M, Hata K, Sado T, Tsujimoto N, et al. (2004) Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting. Nature 429 (6994): 900-3.
    • (2004) Nature , vol.429 , Issue.6994 , pp. 900-903
    • Kaneda, M.1    Okano, M.2    Hata, K.3    Sado, T.4    Tsujimoto, N.5
  • 27
    • 24044481947 scopus 로고    scopus 로고
    • Inactivation of Dnmt3b in mouse embryonic fibroblasts results in DNA hypomethylation, chromosomal instability, and spontaneous immortalization
    • Dodge JE, Okano M, Dick F, Tsujimoto N, Chen T, et al. (2005) Inactivation of Dnmt3b in mouse embryonic fibroblasts results in DNA hypomethylation, chromosomal instability, and spontaneous immortalization. J Biol Chem 280 (18): 17986-91.
    • (2005) J Biol Chem , vol.280 , Issue.18 , pp. 17986-17991
    • Dodge, J.E.1    Okano, M.2    Dick, F.3    Tsujimoto, N.4    Chen, T.5
  • 29
    • 34548603504 scopus 로고    scopus 로고
    • Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation
    • Jia D, Jurkowska RZ, Zhang X, Jeltsch A, Cheng X, (2007) Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation. Nature 449 (7159): 248-51.
    • (2007) Nature , vol.449 , Issue.7159 , pp. 248-251
    • Jia, D.1    Jurkowska, R.Z.2    Zhang, X.3    Jeltsch, A.4    Cheng, X.5
  • 30
    • 36949016699 scopus 로고    scopus 로고
    • Alterations of DNA methylation associated with abnormalities of DNA methyltransferases in human cancers during transition from a precancerous to a malignant state
    • Kanai Y, Hirohashi S, (2007) Alterations of DNA methylation associated with abnormalities of DNA methyltransferases in human cancers during transition from a precancerous to a malignant state. Carcinogenesis 28 (12): 2434-42.
    • (2007) Carcinogenesis , vol.28 , Issue.12 , pp. 2434-2442
    • Kanai, Y.1    Hirohashi, S.2
  • 31
    • 10344260184 scopus 로고    scopus 로고
    • CpG island methylator phenotype in cancer
    • Issa JP, (2004) CpG island methylator phenotype in cancer. Nat Rev Cancer 4 (12): 988-93.
    • (2004) Nat Rev Cancer , vol.4 , Issue.12 , pp. 988-993
    • Issa, J.P.1
  • 32
    • 66649097032 scopus 로고    scopus 로고
    • DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer
    • Nosho K, Shima K, Irahara N, Kure S, Baba Y, et al. (2009) DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer. Clin Cancer Res 15 (11): 3663-71.
    • (2009) Clin Cancer Res , vol.15 , Issue.11 , pp. 3663-3671
    • Nosho, K.1    Shima, K.2    Irahara, N.3    Kure, S.4    Baba, Y.5
  • 33
    • 79958147099 scopus 로고    scopus 로고
    • Sequential DNA methylation changes are associated with DNMT3B overexpression in colorectal neoplasia progression
    • 223602 Published Online
    • Ibrahim AE, Arends MJ, Silva AL, Wyllie AH, Greger L, et al. (2010) Sequential DNA methylation changes are associated with DNMT3B overexpression in colorectal neoplasia progression. Gut 223602 Published Online.
    • (2010) Gut
    • Ibrahim, A.E.1    Arends, M.J.2    Silva, A.L.3    Wyllie, A.H.4    Greger, L.5
  • 34
    • 33749993417 scopus 로고    scopus 로고
    • The consensus coding sequences of human breast and colorectal cancers
    • Sjobolm T, Jones S, Wood LD, (2006) The consensus coding sequences of human breast and colorectal cancers. Science 314: 268-274.
    • (2006) Science , vol.314 , pp. 268-274
    • Sjobolm, T.1    Jones, S.2    Wood, L.D.3
  • 35
    • 0027981314 scopus 로고
    • Thermal denaturation of double-stranded nucleic acids: prediction of temperatures critical for gradient gel electrophoresis and polymerase chain reaction
    • Steger G, (1994) Thermal denaturation of double-stranded nucleic acids: prediction of temperatures critical for gradient gel electrophoresis and polymerase chain reaction. Nucleic Acid Research 22 (14): 2760-2768.
    • (1994) Nucleic Acid Research , vol.22 , Issue.14 , pp. 2760-2768
    • Steger, G.1
  • 36
    • 33846641709 scopus 로고    scopus 로고
    • High resolution melting analysis for the rapid and sensitive detection of mutations in clinical samples: KRAS codon 12 and 13 mutations in non-small cell lung cancer
    • Krypuy M, Newnham GM, Thomsa DM, Conron M, Dobrovic A, (2006) High resolution melting analysis for the rapid and sensitive detection of mutations in clinical samples: KRAS codon 12 and 13 mutations in non-small cell lung cancer. BMC Cancer 6 (295).
    • (2006) BMC Cancer , vol.6 , Issue.295
    • Krypuy, M.1    Newnham, G.M.2    Thomsa, D.M.3    Conron, M.4    Dobrovic, A.5
  • 38
    • 55949107158 scopus 로고    scopus 로고
    • Archived Guthrie blood spots as a novel source for quantitative DNA methylation analysis
    • Wong N, Morley R, Saffery R, Craig J, (2008) Archived Guthrie blood spots as a novel source for quantitative DNA methylation analysis. Biotechniques 45 (4): 423-4.
    • (2008) Biotechniques , vol.45 , Issue.4 , pp. 423-424
    • Wong, N.1    Morley, R.2    Saffery, R.3    Craig, J.4
  • 39
    • 27744577751 scopus 로고    scopus 로고
    • BiQ Analyzer: vizualization and quality control for DNA methylation data from bisulfite sequencing
    • Bock C, Reither S, Mikeska T, Paulsen M, Walter J, et al. (2005) BiQ Analyzer: vizualization and quality control for DNA methylation data from bisulfite sequencing. Bioinformatics 21 (21): 4067-4068.
    • (2005) Bioinformatics , vol.21 , Issue.21 , pp. 4067-4068
    • Bock, C.1    Reither, S.2    Mikeska, T.3    Paulsen, M.4    Walter, J.5
  • 40
    • 7044253667 scopus 로고    scopus 로고
    • BRAF and KRAS Mutations in hyperplastic polyps and serrated adenomas of the colorectum: relationship to histology and CpG island methylation status
    • Yang S, Farraye FA, Mack C, Posnik O, O'Brien MJ, (2004) BRAF and KRAS Mutations in hyperplastic polyps and serrated adenomas of the colorectum: relationship to histology and CpG island methylation status. Am J Surg Pathol 28 (11): 1452-9.
    • (2004) Am J Surg Pathol , vol.28 , Issue.11 , pp. 1452-1459
    • Yang, S.1    Farraye, F.A.2    Mack, C.3    Posnik, O.4    O'Brien, M.J.5
  • 41
    • 39649104991 scopus 로고    scopus 로고
    • DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines
    • Roll JD, Rivenbark AG, Jones WD, Coleman WB, (2008) DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines. Mol Cancer 7: 15.
    • (2008) Mol Cancer , vol.7 , pp. 15
    • Roll, J.D.1    Rivenbark, A.G.2    Jones, W.D.3    Coleman, W.B.4
  • 42
    • 39749152283 scopus 로고    scopus 로고
    • DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function
    • Jin B, Tao Q, Peng J, Soo HM, Wu W, et al. (2008) DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function. Hum Mol Genet 17 (5): 690-709.
    • (2008) Hum Mol Genet , vol.17 , Issue.5 , pp. 690-709
    • Jin, B.1    Tao, Q.2    Peng, J.3    Soo, H.M.4    Wu, W.5
  • 43
    • 34249785078 scopus 로고    scopus 로고
    • Role of BRAF-V600E in the serrated pathway of colorectal tumourigenesis
    • Minoo P, Moyer M, Jass J, (2007) Role of BRAF-V600E in the serrated pathway of colorectal tumourigenesis. J Pathol 212 (2): 124-133.
    • (2007) J Pathol , vol.212 , Issue.2 , pp. 124-133
    • Minoo, P.1    Moyer, M.2    Jass, J.3
  • 45
    • 15244341292 scopus 로고    scopus 로고
    • Association analysis of DNA methyltransferase-1 (DNMT1) polymorphism with systemic lupus erythematosus
    • Park B, Kim LH, Shin HD, Park YW, Uhm WS, et al. (2004) Association analysis of DNA methyltransferase-1 (DNMT1) polymorphism with systemic lupus erythematosus. J Hum Genet 49 (11): 642-6.
    • (2004) J Hum Genet , vol.49 , Issue.11 , pp. 642-646
    • Park, B.1    Kim, L.H.2    Shin, H.D.3    Park, Y.W.4    Uhm, W.S.5
  • 46
    • 0033435205 scopus 로고    scopus 로고
    • The DNMT3B DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome
    • Hansen RS, Wijimenga C, Luo P, Stanek AM, Canfield CM, et al. (1999) The DNMT3B DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome. Proc Natl Acad Sci 96 (25): 14412-14417.
    • (1999) Proc Natl Acad Sci , vol.96 , Issue.25 , pp. 14412-14417
    • Hansen, R.S.1    Wijimenga, C.2    Luo, P.3    Stanek, A.M.4    Canfield, C.M.5
  • 47
  • 48
    • 33748103002 scopus 로고    scopus 로고
    • Genetic variants in epigenetic genes and breast cancer risk
    • Cebrian A, Pharoah PD, Ahmed S, Ropero S, Fraga MF, et al. (2006) Genetic variants in epigenetic genes and breast cancer risk. Carcinogenesis 27 (8): 1661-9.
    • (2006) Carcinogenesis , vol.27 , Issue.8 , pp. 1661-1669
    • Cebrian, A.1    Pharoah, P.D.2    Ahmed, S.3    Ropero, S.4    Fraga, M.F.5
  • 49
    • 13844267367 scopus 로고    scopus 로고
    • DNMT3B polymorphisms and risk of primary lung cancer
    • Lee SJ, Jeon HS, Jang JS, Park SH, Lee GY, et al. (2005) DNMT3B polymorphisms and risk of primary lung cancer. Carcinogenesis 26 (2): 403-9.
    • (2005) Carcinogenesis , vol.26 , Issue.2 , pp. 403-409
    • Lee, S.J.1    Jeon, H.S.2    Jang, J.S.3    Park, S.H.4    Lee, G.Y.5
  • 50
    • 7044254997 scopus 로고    scopus 로고
    • The DNMT3B C-T promoter polymorphism and risk of breast cancer in a british population: a case-control study
    • Montgomery KG, Liu MC, Eccles DM, Campbell IG, (2004) The DNMT3B C-T promoter polymorphism and risk of breast cancer in a british population: a case-control study. Breast cancer Reasearch 6: R390-R394.
    • (2004) Breast Cancer Reasearch , vol.6
    • Montgomery, K.G.1    Liu, M.C.2    Eccles, D.M.3    Campbell, I.G.4
  • 51
    • 79951843188 scopus 로고    scopus 로고
    • A systematic search for DNA methyltransferase polymorphisms reveals a rare DNMT3L variant associated with subtelomeric hypomethylation
    • El-Maarri O, Kareta MS, Mikeska T, Becker T, Diaz-Lacava A, et al. (2009) A systematic search for DNA methyltransferase polymorphisms reveals a rare DNMT3L variant associated with subtelomeric hypomethylation. Hum Mol Genet 26: 26.
    • (2009) Hum Mol Genet , vol.26 , pp. 26
    • El-Maarri, O.1    Kareta, M.S.2    Mikeska, T.3    Becker, T.4    Diaz-Lacava, A.5
  • 52
    • 0035282695 scopus 로고    scopus 로고
    • GeneSplicer: a new computational method for splice site prediction
    • Perta M, Lin X, Salzberg SL, (2001) GeneSplicer: a new computational method for splice site prediction. Nucleic Acid Res 29 (5): 1185-90.
    • (2001) Nucleic Acid Res , vol.29 , Issue.5 , pp. 1185-1190
    • Perta, M.1    Lin, X.2    Salzberg, S.L.3
  • 53
    • 69349097813 scopus 로고    scopus 로고
    • Genoma-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer
    • Amundadottir L, Kraft P, Stolzenberg-Solomon RZ, Fuchs CS, Petersen GM, et al. (2009) Genoma-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer. Nat Genet 41 (9): 986-90.
    • (2009) Nat Genet , vol.41 , Issue.9 , pp. 986-990
    • Amundadottir, L.1    Kraft, P.2    Stolzenberg-Solomon, R.Z.3    Fuchs, C.S.4    Petersen, G.M.5
  • 54
    • 67249117049 scopus 로고    scopus 로고
    • Potential etiologic and functional implications of genome-wide association loci for human disease and traits
    • Hindorff L, Sethupathy P, Junkins HA, Ramos EM, Mehta JP, et al. (2009) Potential etiologic and functional implications of genome-wide association loci for human disease and traits. Proc Natl Acad Sci 106 (23): 9362-7.
    • (2009) Proc Natl Acad Sci , vol.106 , Issue.23 , pp. 9362-9367
    • Hindorff, L.1    Sethupathy, P.2    Junkins, H.A.3    Ramos, E.M.4    Mehta, J.P.5
  • 55
    • 13144266670 scopus 로고    scopus 로고
    • Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
    • Herman JG, Umar A, Polyak K, Graff JR, Ahuja N, et al. (1998) Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. Proc Natl Acad Sci 95 (12): 6870-5.
    • (1998) Proc Natl Acad Sci , vol.95 , Issue.12 , pp. 6870-6875
    • Herman, J.G.1    Umar, A.2    Polyak, K.3    Graff, J.R.4    Ahuja, N.5
  • 57
    • 14644396228 scopus 로고    scopus 로고
    • Detection and interpretation of altered methylation patterns in cancer cells
    • Ushijima T, Watanabe N, Shimizu K, Miyamoto K, Sugimura T, et al. (2005) Detection and interpretation of altered methylation patterns in cancer cells. Nat Rev Cancer 5 (3): 223-231.
    • (2005) Nat Rev Cancer , vol.5 , Issue.3 , pp. 223-231
    • Ushijima, T.1    Watanabe, N.2    Shimizu, K.3    Miyamoto, K.4    Sugimura, T.5
  • 58
    • 34548705374 scopus 로고    scopus 로고
    • Role of the Dnmt3 family in de novo methylation of imprinted and repetitive sequences during male germ cell development in the mouse
    • Kato Y, Kaneda M, Hata K, Kumaki K, Hisano M, et al. (2007) Role of the Dnmt3 family in de novo methylation of imprinted and repetitive sequences during male germ cell development in the mouse. Hum Mol Genet 16 (19): 2272-80.
    • (2007) Hum Mol Genet , vol.16 , Issue.19 , pp. 2272-2280
    • Kato, Y.1    Kaneda, M.2    Hata, K.3    Kumaki, K.4    Hisano, M.5
  • 59
    • 0035930660 scopus 로고    scopus 로고
    • Dnmt3L and the establishment of maternal genomic imprints
    • Bourc'his D, Xu GL, Lin CS, Bollman B, Bestor TH, (2001) Dnmt3L and the establishment of maternal genomic imprints. Science 294: 2536-2539.
    • (2001) Science , vol.294 , pp. 2536-2539
    • Bourc'his, D.1    Xu, G.L.2    Lin, C.S.3    Bollman, B.4    Bestor, T.H.5
  • 60
    • 38449115628 scopus 로고    scopus 로고
    • DNA Methylation Profile at the DNMT3L Promoter: A Potential Biomarker for Cervical Cancer
    • Gokul G, Gautami B, Malathi S, Sowjanya AP, Polli UR, et al. (2007) DNA Methylation Profile at the DNMT3L Promoter: A Potential Biomarker for Cervical Cancer. Epigenetics 2 (2): 80-85.
    • (2007) Epigenetics , vol.2 , Issue.2 , pp. 80-85
    • Gokul, G.1    Gautami, B.2    Malathi, S.3    Sowjanya, A.P.4    Polli, U.R.5
  • 61
    • 69949107733 scopus 로고    scopus 로고
    • Reprogramin of HeLa cells upon DNMT3L overexpression mimics carcinogenesis
    • Gokul G, Ramakrishna G, Khosla S, (2009) Reprogramin of HeLa cells upon DNMT3L overexpression mimics carcinogenesis. Epigenetics 4 (5): 322-9.
    • (2009) Epigenetics , vol.4 , Issue.5 , pp. 322-329
    • Gokul, G.1    Ramakrishna, G.2    Khosla, S.3
  • 62
    • 0023256456 scopus 로고
    • Prevalence of ras gene mutations in human colorectal cancers
    • Boss JL, (1987) Prevalence of ras gene mutations in human colorectal cancers. Nature 327: 293-297.
    • (1987) Nature , vol.327 , pp. 293-297
    • Boss, J.L.1
  • 63
    • 0033043642 scopus 로고    scopus 로고
    • Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways
    • Jass JR, Biden KG, Cummings MC, Simms LA, Walsh M, et al. (1999) Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways. J Clin Pathol 52 (6): 455-60.
    • (1999) J Clin Pathol , vol.52 , Issue.6 , pp. 455-460
    • Jass, J.R.1    Biden, K.G.2    Cummings, M.C.3    Simms, L.A.4    Walsh, M.5
  • 64
    • 0027412665 scopus 로고
    • Prognostic significance of K-ras mutations in colorectal carcinoma
    • Benhattar J, Losi L, Chaubert P, Givel JC, Costa L, (1993) Prognostic significance of K-ras mutations in colorectal carcinoma. Gastroenterology 104 (327): 293-297.
    • (1993) Gastroenterology , vol.104 , Issue.327 , pp. 293-297
    • Benhattar, J.1    Losi, L.2    Chaubert, P.3    Givel, J.C.4    Costa, L.5
  • 65
    • 33846111256 scopus 로고    scopus 로고
    • Alteration of DNA methyltransferases contributes to 5'CpG methylation and poor prognosis in lung cancer
    • Lin RK, Hsu HS, Chang JW, Chen CY, Chen JT, et al. (2007) Alteration of DNA methyltransferases contributes to 5'CpG methylation and poor prognosis in lung cancer. Lung Cancer 55: 205-213.
    • (2007) Lung Cancer , vol.55 , pp. 205-213
    • Lin, R.K.1    Hsu, H.S.2    Chang, J.W.3    Chen, C.Y.4    Chen, J.T.5
  • 66
    • 33745752975 scopus 로고    scopus 로고
    • Hyperplastic polyposis syndrome: phenotypic presentations and the role of MBD4 and MYH
    • Chow E, Lipton L, Lynch E, D'Souza R, Aragona C, et al. (2006) Hyperplastic polyposis syndrome: phenotypic presentations and the role of MBD4 and MYH. Gastroenterology 131 (1): 30-9.
    • (2006) Gastroenterology , vol.131 , Issue.1 , pp. 30-39
    • Chow, E.1    Lipton, L.2    Lynch, E.3    D'Souza, R.4    Aragona, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.