Evaluation of feline oral squamous cell carcinomas for p16CDKN2A protein immunoreactivity and the presence of papillomaviral DNA

Research in Veterinary Science

Volumn 90, Issue 2, 2011, Pages 280-283

  Munday, John S ^a   Knight, Cameron G ^a   French, Adrienne F ^b  

^a MASSEY UNIVERSITY   (New Zealand)

^b New Zealand Veterinary Pathology Ltd   (New Zealand)

Author keywords

Carcinogenesis; Cat; Immunohistochemistry; Oncology; Oral squamous cell carcinoma; P16; Papillomavirus

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; VIRUS DNA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CAT DISEASE; CORRELATIONAL STUDY; IMMUNOREACTIVITY; MOUTH CARCINOMA; NONHUMAN; PAPILLOMA VIRUS; POLYMERASE CHAIN REACTION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SQUAMOUS CELL CARCINOMA; VIRUS DETECTION; VIRUS INFECTION;

ANIMALS; CARCINOMA, SQUAMOUS CELL; CAT DISEASES; CATS; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA, VIRAL; GENE EXPRESSION REGULATION, NEOPLASTIC; IMMUNOHISTOCHEMISTRY; MOUTH NEOPLASMS; PAPILLOMAVIRIDAE;

FELIDAE; PAPILLOMAVIRIDAE;

EID: 79951773866     PISSN: 00345288     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rvsc.2010.06.014     Document Type: Article

References (28)

1. Ai L., Stephenson K.K., Ling W., Zuo C., Mukunyadzi P., Suen J.Y., Hanna E., Fan C.Y. The p16 (CDKN2a/INK4a) tumor-suppressor gene in head and neck squamous cell carcinoma: a promoter methylation and protein expression study in 100 cases. Modern Pathology 2003, 16:944-950.
2. Antonsson A., Hansson B.G. Healthy skin of many animal species harbors papillomaviruses which are closely related to their human counterparts. Journal of Virology 2002, 76:12537-12542.
3. Bertone E.R., Snyder L.A., Moore A.S. Environmental and lifestyle risk factors for oral squamous cell carcinoma in domestic cats. Journal of Veterinary Internal Medicine 2003, 17:557-562.
4. Bova R.J., Quinn D.I., Nankervis J.S., Cole I.E., Sheridan B.F., Jensen M.J., Morgan G.J., Hughes C.J., Sutherland R.L. Cyclin D1 and p16INK4A expression predict reduced survival in carcinoma of the anterior tongue. Clinical Cancer Research 1999, 5:2810-2819.
5. Boyer S.N., Wazer D.E., Band V. E7 protein of human papilloma virus-16 induces degradation of retinoblastoma protein through the ubiquitin-proteasome pathway. Cancer Research 1996, 56:4620-4624.
6. Carter R.T., Giudice C., Dubielzig R.R., Colitz C.M. Telomerase activity with concurrent loss of cell cycle regulation in feline post-traumatic ocular sarcomas. Journal of Comparative Pathology 2005, 133:235-245.
7. Chan S.Y., Delius H., Halpern A.L., Bernard H.U. Analysis of genomic sequences of 95 papillomavirus types: uniting typing, phylogeny, and taxonomy. Journal of Virology 1995, 69:3074-3083.
8. Cunningham L.L., Pagano G.M., Li M., Tandon R., Holm S.W., White D.K., Lele S.M. Overexpression of p16INK4 is a reliable marker of human papillomavirus-induced oral high-grade squamous dysplasia. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics 2006, 102:77-81.
9. Forslund O., Antonsson A., Nordin P., Stenquist B., Hansson B.G. A broad range of human papillomavirus types detected with a general PCR method suitable for analysis of cutaneous tumours and normal skin. Journal of General Virology 1999, 80:2437-2443.
10. Foulkes W.D., Flanders T.Y., Pollock P.M., Hayward N.K. The CDKN2A (p16) gene and human cancer. Molecular Medicine 1997, 3:5-20.
11. Geisler S.A., Olshan A.F., Weissler M.C., Cai J., Funkhouser W.K., Smith J., Vick K. P16 and p53 Protein expression as prognostic indicators of survival and disease recurrence from head and neck cancer. Clinical Cancer Research 2002, 8:3445-3453.
12. Gillison M.L., Koch W.M., Capone R.B., Spafford M., Westra W.H., Wu L., Zahurak M.L., Daniel R.W., Viglione M., Symer D.E., Shah K.V., Sidransky D. Evidence for a causal association between human papillomavirus and a subset of head and neck cancers. Journal of the National Cancer Institute 2000, 92:709-720.
13. Head K.W., Else R.W., Dubielzig R.R. Tumors of the alimentary tract. Tumors in Domestic Animals 2002, 401-481. Iowa State Press, Ames, Iowa. D.J. Meuten (Ed.).
14. Kim D.H., Nelson H.H., Wiencke J.K., Zheng S., Christiani D.C., Wain J.C., Mark E.J., Kelsey K.T. P16(INK4a) and histology-specific methylation of CpG islands by exposure to tobacco smoke in non-small cell lung cancer. Cancer Research 2001, 61:3419-3424.
15. Konig F., Krekeler G., Honig J.F., Cordon-Cardo C., Fischer G., Korabiowska M. Relation between human papillomavirus positivity and p16 expression in head and neck carcinomas-a tissue microarray study. Anticancer Research 2007, 27:283-288.
16. Lingen M.W. Head and Neck. Robins and Cotran Pathologic Basis of Disease 2010, 739-762. Elsevier Saunders, Philadelphia, Pennsylvania. V. Kumar, A.K. Abbas, N. Fausto, J.C. Aster (Eds.).
17. Muirhead D.M., Hoffman H.T., Robinson R.A. Correlation of clinicopathological features with immunohistochemical expression of cell cycle regulatory proteins p16 and retinoblastoma: distinct association with keratinisation and differentiation in oral cavity squamous cell carcinoma. Journal of Clinical Pathology 2006, 59:711-715.
18. Munday J.S., Kiupel M., French A.F., Howe L., Squires R.A. Detection of papillomaviral sequences in feline Bowenoid in situ carcinoma using consensus primers. Veterinary Dermatology 2007, 18:241-245.
19. Munday J.S., Howe L., French A., Squires R.A., Sugiarto H. Detection of papillomaviral DNA sequences in a feline oral squamous cell carcinoma. Research in Veterinary Science 2009, 86:359-361.
20. Munday, J.S., French, A.F., Peters-Kennedy, J., Orbell, G.M.B. Gwynne, K., 2010. Increased p16CDKN2A protein within feline cutaneous viral plaques, Bowenoid in situ carcinomas, and a subset of invasive squamous cell carcinomas. Veterinary Pathology 47, in press.
21. Ohtani N., Yamakoshi K., Takahashi A., Hara E. The p16INK4a-RB pathway: molecular link between cellular senescence and tumor suppression. Journal of Medical Investigation 2004, 51:146-153.
22. Papadimitrakopoulou V., Izzo J., Lippman S.M., Lee J.S., Fan Y.H., Clayman G., Ro J.Y., Hittelman W.N., Lotan R., Hong W.K., Mao L. Frequent inactivation of p16INK4a in oral premalignant lesions. Oncogene 1997, 14:1799-1803.
23. Parry D., Bates S., Mann D.J., Peters G. Lack of cyclin D-Cdk complexes in Rb-negative cells correlates with high levels of p16INK4/MTS1 tumour suppressor gene product. The EMBO Journal 1995, 14:503-511.
24. Reimers N., Kasper H.U., Weissenborn S.J., Stutzer H., Preuss S.F., Hoffmann T.K., Speel E.J., Dienes H.P., Pfister H.J., Guntinas-Lichius O., Klussmann J.P. Combined analysis of HPV-DNA, p16 and EGFR expression to predict prognosis in oropharyngeal cancer. International Journal of Cancer 2007, 120:1731-1738.
25. Smith E.M., Wang D., Kim Y., Rubenstein L.M., Lee J.H., Haugen T.H., Turek L.P. P16INK4a expression, human papillomavirus, and survival in head and neck cancer. Oral Oncology 2008, 44:133-142.
26. Smith K.T., Campo M.S. "Hit and run" transformation of mouse C127 cells by bovine papillomavirus type 4: the viral DNA is required for the initiation but not for maintenance of the transformed phenotype. Virology 1988, 164:39-47.
27. Stricker T.P., Kumar V. Neoplasia. Robins and Cotran Pathologic Basis of Disease 2010, 259-330. Elsevier Saunders, Philadelphia, Pennsylvania. V. Kumar, A.K. Abbas, N. Fausto, J.C. Aster (Eds.).
28. Weinberger P.M., Yu Z., Haffty B.G., Kowalski D., Harigopal M., Sasaki C., Rimm D.L., Psyrri A. Prognostic significance of p16 protein levels in oropharyngeal squamous cell cancer. Clinical Cancer Research 2004, 10:5684-5691.