The p16 (CDKN2a/INK4a) tumor-suppressor gene in head and neck squamous cell carcinoma: A promoter methylation and protein expression study in 100 cases

Modern Pathology

Volumn 16, Issue 9, 2003, Pages 944-950

  Ai, Lingbao ^a,c   Stephenson, Krystal K ^a   Ling, Wenhua ^c   Zuo, Chunlai ^a   Mukunyadzi, Perkins ^a   Suen, James Y ^b   Hanna, Ehab ^b   Fan, Chun Yang ^a,b,d  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c SUN YAT SEN UNIVERSITY   (China)

^d CENTRAL ARKANSAS VETERANS HEALTHCARE SYSTEM   (United States)

Author keywords

Gene inactivation; Head and neck squamous cell carcinoma; p16; Promoter hypermethylation

Indexed keywords

ALCOHOL; ANTINEOPLASTIC AGENT; PROTEIN P16;

ADULT; AGED; ALCOHOL CONSUMPTION; ARTICLE; CANCER GRADING; CANCER STAGING; CANCER SURVIVAL; CLINICAL FEATURE; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; FOLLOW UP; GENE INACTIVATION; HEAD AND NECK CANCER; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; METHYLATION; POLYMERASE CHAIN REACTION; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROMOTER REGION; PROTEIN EXPRESSION; SMOKING; SQUAMOUS CELL CARCINOMA; STATISTICAL SIGNIFICANCE; TOBACCO; TUMOR SUPPRESSOR GENE; TUMOR VOLUME;

ADULT; AGED; ALCOHOL DRINKING; CARCINOMA, SQUAMOUS CELL; DNA METHYLATION; DNA, NEOPLASM; GENES, P16; HEAD AND NECK NEOPLASMS; HUMANS; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; POLYMERASE CHAIN REACTION; PROGNOSIS; PROMOTER REGIONS (GENETICS); RISK FACTORS; SMOKING; TUMOR MARKERS, BIOLOGICAL;

EID: 0141519075     PISSN: 08933952     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.MP.0000085760.74313.DD     Document Type: Article

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