Overexpression of p16INK4 is a reliable marker of human papillomavirus-induced oral high-grade squamous dysplasia

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology

Volumn 102, Issue 1, 2006, Pages 77-81

  Cunningham Jr , Larry L ^a   Pagano, Giulia M ^a   Li, Mengtao ^a   Tandon, Rahul ^a   Holm, Stephen W ^b   White, Dean K ^a   Lele, Subodh M ^c  

^a UNIVERSITY OF KENTUCKY COLLEGE OF DENTISTRY   (United States)

^b Carle Clinic   (United States)

^c UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P16INK4A; TUMOR MARKER; VIRUS DNA;

ADULT; AGED; ARTICLE; BIOSYNTHESIS; DNA PROBE; ENZYMOLOGY; FEMALE; HUMAN; HUMAN PAPILLOMAVIRUS TYPE 16; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MOUTH TUMOR; PATHOGENICITY; PRECANCER; SQUAMOUS CELL CARCINOMA; VIROLOGY; VIRUS INFECTION;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA PROBES, HPV; DNA, VIRAL; FEMALE; HUMAN PAPILLOMAVIRUS 16; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MOUTH NEOPLASMS; PAPILLOMAVIRUS INFECTIONS; PRECANCEROUS CONDITIONS; TUMOR MARKERS, BIOLOGICAL;

EID: 33745740651     PISSN: 10792104     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tripleo.2005.11.028     Document Type: Article

References (16)

1. Eversole L.R. Papillary lesions of the oral cavity. relationship to human papillomaviruses. J Calif Dent Assoc 28 (2000) 922-927
2. Schwartz S.M., Daling J.R., Doody D.R., Wipf G.C., Carter J.J., Madeleine M.M., et al. Oral cancer risk in relation to sexual history and evidence of human papillomavirus infection. J Natl Cancer Inst 90 (1998) 1626-1636
3. Young S.K., and Min K.W. In situ DNA hybridization analysis of oral papillomas, leukoplakias, and carcinomas for human papillomavirus. Oral Surg Oral Med Oral Pathol 71 (1991) 726-729
4. Bouda M., Gorgoulis V.G., Kastrinakis N.G., Giannoudis A., Tsoli E., Danassi-Afentaki D., et al. "High risk" HPV types are frequently detected in potentially malignant and malignant oral lesions, but not in normal oral mucosa. Mod Pathol 13 (2000) 644-653
5. Elamin F., Steingrimsdottir H., Wanakulasuriya S., Johnson N., and Tavassoli M. Prevalence of human papillomavirus infection in premalignant and malignant lesions of the oral cavity in UK subjects. a novel method of detection. Oral Oncol 34 (1998) 191-197
6. Abdelsayed R.A. Study of human papillomavirus in oral epithelial dysplasia and epidermoid carcinoma in the absence of tobacco and alcohol use. Oral Surg Oral Med Oral Pathol 71 (1991) 730-732
7. Shroyer K.R., Lovelace G.S., Abarca M.L., Fennell R.H., Corkill M.E., Woodard W.D., et al. Detection of human papillomavirus DNA by in situ hybridization and polymerase chain reaction in human papillomavirus equivocal and dysplastic cervical biopsies. Hum Pathol 24 (1993) 1012-1016
8. Yuen P.W., Man M., Lam K.Y., and Kwong Y.L. Clinicopathological significance of p16 gene expression in the surgical treatment of head and neck squamous cell carcimonas. J Clin Pathol 55 (2002) 58-60
9. Fregonesi P., Teresa D.B., Duarte R.A., Neto C.B., de Oliveira M., and Soares C.P. p16(INK4A) immunohistochemical overexpression in premalignant and malignant oral lesions infected with human papillomavirus. J Histochem Cytochem 51 (2003) 1291-1297
10. Lele S.M., Pou A.M., Ventura K., Gatalica Z., and Payne D. Molecular events in the progression of recurrent respiratory papillomatosis to carcinoma. Arch Pathol Lab Med 126 (2002) 1184-1188
11. Ke L.D., Adler-Storthz M., Mitchell F., Clayman G.L., and Chen Z. Expression of human papillomavirus E7 mRNA in human oral and cervical neoplasia and cell lines. Oral Oncol 35 (1999) 415-420
12. Gillison M.L., Koch W.M., Capone R.B., Spafford M., Westra W.H., Wu L., et al. Evidence for a causal association between human papillomavirus and a subset of head and neck cancers. J Natl Cancer Inst 92 (2000) 709-720
13. Dai M., Clifford G.M., le Calvez F., Castellsague X., Snijders P.J., Pawlita M., et al. Human papillomavirus type 16 and TP53 mutation in oral cancer. matched analysis of the IARC multicenter study. Cancer Res 64 (2004) 468-471
14. Fregonesi P.A., Teresa D.B., Duarte R.A., Neto C.B., de Oliveira M.R., and Soares C.P. p16(INK4A) immunohistochemical overexpression in premalignant and malignant oral lesions infected with human papillomavirus. J Histochem Cytochem 51 (2003) 1291-1297
15. Praetorius F. HPV-associated diseases of oral mucosa. Clin Dermatol 15 (1997) 399-413
16. Sugiyama M., Bhawal U.K., Dohmen T., Ono S., Miyauchi M., and Ishikawa T. Detection of human papillomavirus-16 and HPV-18 DNA in normal, dysplastic, and malignant oral epithelium. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 95 (2003) 594-600