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Volumn 57, Issue 3, 2011, Pages 498-507

Novel therapeutic approaches to lupus glomerulonephritis: Translating animal models to clinical practice

Author keywords

gene therapy; glomerular targeting; glomerulonephritis; immunoliposomes; lupus nephritis; Mesangial cells; mouse models

Indexed keywords

IMMUNOLIPOSOME; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE;

EID: 79951771261     PISSN: 02726386     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.ajkd.2010.10.052     Document Type: Article
Times cited : (14)

References (60)
  • 1
    • 0001968415 scopus 로고    scopus 로고
    • Systemic lupus erythematosus
    • Neilson EG, Couser WG, eds. 2nd ed. Philadelphia, PA: Lippincott, Williams & Wilkins
    • Cameron JS. Systemic lupus erythematosus. In: Neilson EG, Couser WG, eds. Immunologic Renal Diseases. 2nd ed. Philadelphia, PA: Lippincott, Williams & Wilkins; 2001:1057-1104.
    • (2001) Immunologic Renal Diseases , pp. 1057-1104
    • Cameron, J.S.1
  • 2
    • 0034687429 scopus 로고    scopus 로고
    • Efficacy of mycophenylate mofetil in patients with diffuse proliferative lupus nephritis
    • Hong Kong Guangzhou Nephrology Study Group
    • Chan TM, Li FK, Tang CS, et al. Efficacy of mycophenylate mofetil in patients with diffuse proliferative lupus nephritis. Hong Kong Guangzhou Nephrology Study Group. N Engl J Med. 2000;343(16):1156-1162.
    • (2000) N Engl J Med , vol.343 , Issue.16 , pp. 1156-1162
    • Chan, T.M.1    Li, F.K.2    Tang, C.S.3
  • 4
    • 13544259968 scopus 로고    scopus 로고
    • B cell selection and susceptibility to autoimmunity
    • Grimaldi CM, Hicks R, Diamond B. B Cell selection and susceptibility to autoimmunity. J Immunol. 2005;174(4):1775-1781. (Pubitemid 40223915)
    • (2005) Journal of Immunology , vol.174 , Issue.4 , pp. 1775-1781
    • Grimaldi, C.M.1    Hicks, R.2    Diamond, B.3
  • 5
    • 0141955150 scopus 로고    scopus 로고
    • T cell rewiring in differentiation and disease
    • Krishnan S, Farber DL, Tsokos GC. T Cell rewiring in differentiation and disease. J Immunol. 2003;171(7):3325-3331. (Pubitemid 37254530)
    • (2003) Journal of Immunology , vol.171 , Issue.7 , pp. 3325-3331
    • Krishnan, S.1    Farber, D.L.2    Tsokos, G.C.3
  • 6
    • 17044393073 scopus 로고    scopus 로고
    • + T cells from lupus-prone Fas-intact MRL mice display TCR-mediated hyperproliferation due to intrinsic threshold defects in activation
    • + T cells from lupus-prone Fas-intact MRL mice display TCR-mediated hyperproliferation due to intrinsic threshold defects in activation. J Immunol. 2005;174(8):5100-5109.
    • (2005) J Immunol , vol.174 , Issue.8 , pp. 5100-5109
    • Zielinski, C.E.1    Jacob, S.N.2    Bouzahzah, F.3    Ehrlich, B.E.4    Craft, J.5
  • 7
    • 0141891339 scopus 로고    scopus 로고
    • Morbidity and mortality in systemic lupus erythematosus during a 10-year period: A comparison of early and late manifestations in a cohort of 1,000 patients
    • European Working Party on Systemic Lupus Erythematosus
    • Cervera R, Khamashta MA, Font J, et al. European Working Party on Systemic Lupus Erythematosus. Morbidity and mortality in systemic lupus erythematosus during a 10-year period: a comparison of early and late manifestations in a cohort of 1,000 patients. Medicine (Baltimore). 2003;82(5):299 308.
    • (2003) Medicine (Baltimore) , vol.82 , Issue.5 , pp. 299-308
    • Cervera, R.1    Khamashta, M.A.2    Font, J.3
  • 8
    • 0014572788 scopus 로고
    • Renal histologic findings in systemic lupus erythematosus
    • Pollack VE, Pirani CL. Renal histologic findings in systemic lupus erythematosus. Mayo Clin Proc. 1969;44(9):630-644.
    • (1969) Mayo Clin Proc , vol.44 , Issue.9 , pp. 630-644
    • Pollack, V.E.1    Pirani, C.L.2
  • 9
    • 76349107593 scopus 로고    scopus 로고
    • Pathogenesis of human systemic lupus erythematosus: Recent advances
    • Crispín JC, Liossis SN, Kis-Toth K, et al. Pathogenesis of human systemic lupus erythematosus: recent advances. Trends Mol Med. 2010;16(2):47-57.
    • (2010) Trends Mol Med , vol.16 , Issue.2 , pp. 47-57
    • Crispín, J.C.1    Liossis, S.N.2    Kis-Toth, K.3
  • 11
    • 0033577903 scopus 로고    scopus 로고
    • A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus
    • Chan OT, Hannum LG, HabermanAM, Madaio MP, Shlomchik MJ. A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus. J Exp Med. 1999;189(10):1639-1648.
    • (1999) J Exp Med , vol.189 , Issue.10 , pp. 1639-1648
    • Chan, O.T.1    Hannum, L.G.2    Haberman, A.M.3    Madaio, M.P.4    Shlomchik, M.J.5
  • 12
    • 31544445804 scopus 로고    scopus 로고
    • B-cell targeted therapies in rheumatoid arthritis and systemic lupus erythematosus
    • DOI 10.1038/ncprheum0042, PII N0042
    • Eisenberg R, Albert D. B-Cell targeted therapies in rheumatoid arthritis and systemic lupus erythematosus. Nat Clin Pract Rheumatol. 2006;2(1):20-27. (Pubitemid 43153645)
    • (2006) Nature Clinical Practice Rheumatology , vol.2 , Issue.1 , pp. 20-27
    • Eisenberg, R.1    Albert, D.2
  • 13
    • 75149150898 scopus 로고    scopus 로고
    • Efficacy and safety of rituximab in subjects with active proliferative lupus nephritis (Ln): Results from the randomized, double-blind phase III LUNAR Study
    • ACR abstract 1149
    • Furie R, Looney RJ, Rovin B, et al. Efficacy and safety of rituximab in subjects with active proliferative lupus nephritis (Ln): results from the randomized, double-blind phase III LUNAR Study. (ACR abstract 1149) Arthritis Rheum. 2009;60(suppl 10):271.
    • (2009) Arthritis Rheum , vol.60 , Issue.SUPPL. 10 , pp. 271
    • Furie, R.1    Looney, R.J.2    Rovin, B.3
  • 14
    • 70350153802 scopus 로고    scopus 로고
    • Glomerular disease: Lupus nephritis trials end in disappointment
    • Harman C. Glomerular disease: lupus nephritis trials end in disappointment. Nat Rev Nephrol. 2009;5(6):303.
    • (2009) Nat Rev Nephrol , vol.5 , Issue.6 , pp. 303
    • Harman, C.1
  • 15
    • 74849131972 scopus 로고    scopus 로고
    • Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: The randomized, double-blind, phase II/III systemic lupus erythematosus evaluation of rituximab trial
    • Merrill JT, Neuwelt CM, Wallace DJ, et al. Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: the randomized, double-blind, phase II/III systemic lupus erythematosus evaluation of rituximab trial. Arthritis Rheum. 2010;62(1):222-233.
    • (2010) Arthritis Rheum , vol.62 , Issue.1 , pp. 222-233
    • Merrill, J.T.1    Neuwelt, C.M.2    Wallace, D.J.3
  • 16
    • 77649117940 scopus 로고    scopus 로고
    • Enhanced selection of high affinity DNA-reactive B cells following cyclophosphamide treatment in mice
    • Kawabata D, Venkatesh J, Ramanujam M, Davidson A, Grimaldi CM, Diamond B. Enhanced selection of high affinity DNA-reactive B cells following cyclophosphamide treatment in mice. PLoS One. 2010;5(1):e8418.
    • (2010) PLoS One , vol.5 , Issue.1
    • Kawabata, D.1    Venkatesh, J.2    Ramanujam, M.3    Davidson, A.4    Grimaldi, C.M.5    Diamond, B.6
  • 17
    • 77951739752 scopus 로고    scopus 로고
    • Selective blockade of BAFF for the prevention and treatment of systemic lupus erythematosus nephritis in NZM2410 mice
    • Ramanujam M, Bethunaickan R, Huang W, Tao H, Madaio MP, Davidson A. Selective blockade of BAFF for the prevention and treatment of systemic lupus erythematosus nephritis in NZM2410 mice. Arthritis Rheum. 2010;62(5):1457-1468.
    • (2010) Arthritis Rheum , vol.62 , Issue.5 , pp. 1457-1468
    • Ramanujam, M.1    Bethunaickan, R.2    Huang, W.3    Tao, H.4    Madaio, M.P.5    Davidson, A.6
  • 18
    • 68849084069 scopus 로고    scopus 로고
    • Systemic lupus erythematosus clinical trials-an interim analysis
    • Dall'Era M, Wofsy D. Systemic lupus erythematosus clinical trials-an interim analysis. Nat Rev Rheumatol. 2009;5(6):348-351.
    • (2009) Nat Rev Rheumatol , vol.5 , Issue.6 , pp. 348-351
    • Dall'Era, M.1    Wofsy, D.2
  • 19
    • 77749270418 scopus 로고    scopus 로고
    • Connective tissue diseases: Belimumab for systemic lupus erythematosus: Breaking through?
    • Dall'Era M, Wofsy D. Connective tissue diseases: belimumab for systemic lupus erythematosus: breaking through? Nat Rev Rheumatol. 2010;6(3):124-125.
    • (2010) Nat Rev Rheumatol , vol.6 , Issue.3 , pp. 124-125
    • Dall'Era, M.1    Wofsy, D.2
  • 22
    • 0034868803 scopus 로고    scopus 로고
    • NZM2328: A new mouse model of systemic lupus erythematosus with unique genetic susceptibility loci
    • Waters ST, Fu SM, Gaskin F, et al. NZM2328: a new mouse model of systemic lupus erythematosus with unique genetic susceptibility loci. Clin Immunol. 2001;100(3):372-383.
    • (2001) Clin Immunol , vol.100 , Issue.3 , pp. 372-383
    • Waters, S.T.1    Fu, S.M.2    Gaskin, F.3
  • 23
    • 0027230775 scopus 로고
    • Differences in expression of lupus nephritis in New Zealand mixed H-2z-homozygous inbred strains of mice derived from New Zealand black and New Zealand white mice
    • Rudofsky UH, Evans BD, Balaban SL, Mottironi VD, Gabrielsen AE. Differences in expression of lupus nephritis in New Zealand mixed H-2z-homozygous inbred strains of mice derived from New Zealand black and New Zealand white mice. Lab Invest. 1993;68(4):419-425.
    • (1993) Lab Invest , vol.68 , Issue.4 , pp. 419-425
    • Rudofsky, U.H.1    Evans, B.D.2    Balaban, S.L.3    Mottironi, V.D.4    Gabrielsen, A.E.5
  • 25
    • 0032006599 scopus 로고    scopus 로고
    • Loci predisposing to autoimmunity in MRL-Fas(lpr) and C57BL/6-Fas(lpr) mice
    • Vidal S, Kono DH, Theofilopoulous AN. Loci predisposing to autoimmunity in MRL-Fas lpr and C57BL/6-Faslpr mice. J Clin Invest. 1998;101(3):696-702. (Pubitemid 28084255)
    • (1998) Journal of Clinical Investigation , vol.101 , Issue.3 , pp. 696-702
    • Vidal, S.1    Kono, D.H.2    Theofilopoulos, A.N.3
  • 26
    • 0034820924 scopus 로고    scopus 로고
    • Of mice and men: The relevance of the mouse to the study of human SLE
    • DOI 10.1385/IR:24:2:211
    • Birmingham DJ, Rovin BH, Yu CY, Hebert LA. Of mice and men: the relevance of the mouse to the study of human SLE. Immunol Res. 2001;24(2):211-224. (Pubitemid 32897080)
    • (2001) Immunologic Research , vol.24 , Issue.2 , pp. 211-224
    • Birmingham, D.J.1    Rovin, B.H.2    Yung, Y.C.3    Hebert, L.A.4
  • 27
    • 0026753816 scopus 로고
    • Anti-DNA antibodies form immune deposits at distinct glomerular and vascular sites
    • Vlahakos DV, Foster MH, Adams S, et al. Anti-DNA antibodies form immune deposits at distinct glomerular and vascular sites. Kidney Int. 1992;41(6):1690-1700.
    • (1992) Kidney Int , vol.41 , Issue.6 , pp. 1690-1700
    • Vlahakos, D.V.1    Foster, M.H.2    Adams, S.3
  • 28
    • 34447315527 scopus 로고    scopus 로고
    • Experimental anti-GBM disease as a tool for studying spontaneous lupus nephritis
    • DOI 10.1016/j.clim.2007.05.007, PII S1521661607012168
    • Fu Y, Du Y, Mohan C. Experimental anti-GBM disease as a tool for studying spontaneous lupus nephritis. Clin Immunol. 2007;124(2):109-118. (Pubitemid 47059046)
    • (2007) Clinical Immunology , vol.124 , Issue.2 , pp. 109-118
    • Fu, Y.1    Du, Y.2    Mohan, C.3
  • 29
    • 31544457088 scopus 로고    scopus 로고
    • Simvastatin protection against acute immune-mediated glomerulonephritis in mice
    • DOI 10.1038/sj.ki.5000086, PII 5000086
    • Christensen M, Su AW, Snyder RW, Greco A, Lipschutz JH, Madaio MP. Simvastatin protection against acute immunemediated glomerulonephritis in mice. Kidney Int. 2006;69(3):457-463. (Pubitemid 43164436)
    • (2006) Kidney International , vol.69 , Issue.3 , pp. 457-463
    • Christensen, M.1    Su, A.W.2    Snyder, R.W.3    Greco, A.4    Lipschutz, J.H.5    Madaio, M.P.6
  • 31
    • 0025073326 scopus 로고
    • Lupus nephritis: Correlation of interstitial cells with glomerular function
    • Alexopoulos E, Seron D, Hartley RB, Cameron JS. Lupus nephritis: correlation of interstitial cells with glomerular function. Kidney Int. 1990;37(1):100-109. (Pubitemid 20023773)
    • (1990) Kidney International , vol.37 , Issue.1 , pp. 100-109
    • Alexopoulos, E.1    Seron, D.2    Hartley, R.B.3    Cameron, J.S.4
  • 33
    • 33751554877 scopus 로고    scopus 로고
    • Role for nephritogenic T cells in lupus glomerulonephritis: Progression to renal failure is accompanied by T cell activation and expansion in regional lymph nodes
    • Bagavant H, Deshmukh US, Wang H, Ly T, Fu SM. Role for nephritogenic T cells in lupus glomerulonephritis: progression to renal failure is accompanied by T cell activation and expansion in regional lymph nodes. J Immunol. 2006;177(11):8258-8265. (Pubitemid 44846348)
    • (2006) Journal of Immunology , vol.177 , Issue.11 , pp. 8258-8265
    • Bagavant, H.1    Deshmukh, U.S.2    Wang, H.3    Ly, T.4    Shu, M.F.5
  • 34
    • 0026673844 scopus 로고
    • + T cells is required to suppress autoimmunity
    • + T cells is required to suppress autoimmunity. J Immunol. 1992;149(9):3083-3088.
    • (1992) J Immunol , vol.149 , Issue.9 , pp. 3083-3088
    • Connolly, K.1    Roubinian, J.R.2    Wofsy, D.3
  • 35
    • 55249113624 scopus 로고    scopus 로고
    • Increased survival and reduced renal injury in MRL/lpr mice treated with a novel sphingosine-1-phosphate receptor agonist
    • Wenderfer SE, Stepkowski SM, Braun MC. Increased survival and reduced renal injury in MRL/lpr mice treated with a novel sphingosine-1-phosphate receptor agonist. Kidney Int. 2008;4(10):1319-1326.
    • (2008) Kidney Int , vol.4 , Issue.10 , pp. 1319-1326
    • Wenderfer, S.E.1    Stepkowski, S.M.2    Braun, M.C.3
  • 36
    • 0035284737 scopus 로고    scopus 로고
    • Cutting edge: Reversal of murine lupus nephritis with CTLA4Ig and cyclophosphamide
    • Daikh DI, Wofsy D. Cutting edge: reversal of murine lupus nephritis with CTLA4Ig and cyclophosphamide. J Immunol. 2001;166(5):2913-2916. (Pubitemid 33117284)
    • (2001) Journal of Immunology , vol.166 , Issue.5 , pp. 2913-2916
    • Daikh, D.I.1    Wofsy, D.2
  • 37
    • 0037868032 scopus 로고    scopus 로고
    • 1 mice by a mechanism downstream of renal immune complex deposition
    • Schiffer L, Sinha J,Wang X, et al. Short term administration of costimulatory blockade and cyclophosphamide induces remission of systemic lupus erythematosus nephritis in NZB/W F1 mice by a mechanism downstream of renal immune complex deposition. J Immunol. 2003;171(1):489-497. (Pubitemid 36745324)
    • (2003) Journal of Immunology , vol.171 , Issue.1 , pp. 489-497
    • Schiffer, L.1    Sinha, J.2    Wang, X.3    Huang, W.4    Von, G.G.5    Schiffer, M.6    Madaio, M.P.7    Davidson, A.8
  • 38
    • 23244463009 scopus 로고    scopus 로고
    • + T cells from lupus-prone mice to suppress lupus glomerulonephritis and sialoadenitis
    • + T cells from lupus-prone mice to suppress lupus glomerulonephritis and sialoadenitis. J Immunol. 2005;175(2):944-950.
    • (2005) J Immunol , vol.175 , Issue.2 , pp. 944-950
    • Bagavant, H.1    Tung, K.S.2
  • 40
    • 1842423817 scopus 로고    scopus 로고
    • Strain Distribution Pattern of Susceptibility to Immune-Mediated Nephritis
    • Xie C, Sharma R, Wang H, Zhou XJ, Mohan C. Strain distribution pattern of susceptibility to immune-mediated nephritis. J Immunol. 2004;172(8):5047-5055. (Pubitemid 38456432)
    • (2004) Journal of Immunology , vol.172 , Issue.8 , pp. 5047-5055
    • Xie, C.1    Sharma, R.2    Wang, H.3    Zhou, X.J.4    Mohan, C.5
  • 41
    • 65249086734 scopus 로고    scopus 로고
    • Kallikrein genes are associated with lupus and glomerular basement membrane-specific antibody-induced nephritis in mice and humans
    • Liu K, Li QZ, Delgado-Vega AM, et al. Kallikrein genes are associated with lupus and glomerular basement membrane-specific antibody-induced nephritis in mice and humans. J Clin Invest. 2009;119(4):911-923.
    • (2009) J Clin Invest , vol.119 , Issue.4 , pp. 911-923
    • Liu, K.1    Li, Q.Z.2    Delgado-Vega, A.M.3
  • 42
    • 34247647106 scopus 로고    scopus 로고
    • Advances in targeting drug delivery to glomerular mesangial cells by long circulating cationic liposomes for the treatment of glomerulonephritis
    • DOI 10.1007/s11095-006-9213-0
    • Morimoto K, Kondo M, Kawahara K, et al. Advances in targeting drug delivery to glomerular mesangial cells by long circulating cationic liposomes for the treatment of glomerulonephritis. Pharm Res. 2007;24(5):946-954. (Pubitemid 46675395)
    • (2007) Pharmaceutical Research , vol.24 , Issue.5 , pp. 946-954
    • Morimoto, K.1    Kondo, M.2    Kawahara, K.3    Ushijima, H.4    Tomino, Y.5    Miyajima, M.6    Kimura, J.7
  • 43
    • 0029444559 scopus 로고
    • Surrogate cells or Trojan horses: The discovery of liposomes
    • Bangham A. Surrogate cells or Trojan horses: the discovery of liposomes. Bioessays. 1995;17(21):1081-1088.
    • (1995) Bioessays , vol.17 , Issue.21 , pp. 1081-1088
    • Bangham, A.1
  • 44
    • 37249002059 scopus 로고    scopus 로고
    • Anatomy of the kidney. Elements of normal renal structure and function
    • Brenner BM, ed. 7th ed. Philadelphia, PA: W.B. Saunders Co
    • Madsen K, Tisher CC. Anatomy of the kidney. Elements of normal renal structure and function. In: Brenner BM, ed. Brenner & Rector's The Kidney. 7th ed. Philadelphia, PA: W.B. Saunders Co; 2004:3-72.
    • (2004) Brenner & Rector's the Kidney , pp. 3-72
    • Madsen, K.1    Tisher, C.C.2
  • 45
    • 0037378431 scopus 로고    scopus 로고
    • Specific inhibition of Egr-1 prevents mesangial cell hypercellularity in experimental nephritis
    • DOI 10.1046/j.1523-1755.2003.00865.x
    • Carl MY, Akagi S, Weidner S, Isaka Y, Imai E, Rupprecht HD. Specific inhibition of Egr-1 prevents mesangial cell hypercellularity in experimental nephritis. Kidney Int. 2003;63(4):1302-1312. (Pubitemid 36349996)
    • (2003) Kidney International , vol.63 , Issue.4 , pp. 1302-1312
    • Carl, M.1    Akagi, Y.2    Weidner, S.3    Isaka, Y.4    Imai, E.5    Rupprecht, H.D.6
  • 46
    • 10044226685 scopus 로고    scopus 로고
    • Gene therapy with an E2F transcription factor decoy inhibits cell cycle progression in rat anti-Thy 1 glomerulonephritis
    • Tomita N, Kim JY, Gibbons GH, et al. Gene therapy with an E2F transcription factor decoy inhibits cell cycle progression in rat anti-Thy 1 glomerulonephritis. Int J Mol Med. 2004;13(5):629-636.
    • (2004) Int J Mol Med , vol.13 , Issue.5 , pp. 629-636
    • Tomita, N.1    Kim, J.Y.2    Gibbons, G.H.3
  • 48
    • 77950611468 scopus 로고    scopus 로고
    • siRNA-based therapy ameliorates glomerulonephritis
    • Shimizu H, Hori Y, Kaname S, et al. siRNA-based therapy ameliorates glomerulonephritis. J Am Soc Nephrol. 2004;21(4):622-633.
    • (2004) J Am Soc Nephrol , vol.21 , Issue.4 , pp. 622-633
    • Shimizu, H.1    Hori, Y.2    Kaname, S.3
  • 49
    • 0033167922 scopus 로고    scopus 로고
    • Gene therapy using HVJ-liposomes: The best of both worlds?
    • DOI 10.1016/S1357-4310(99)01482-3, PII S1357431099014823
    • Kaneda Y, Saeki Y, Morishita R. Gene therapy using HVJ liposomes: the best of both worlds. Mol Med Today. 1999;5(7):298-303. (Pubitemid 29302677)
    • (1999) Molecular Medicine Today , vol.5 , Issue.7 , pp. 298-303
    • Kaneda, Y.1    Saeki, Y.2    Morishita, R.3
  • 50
    • 41149118880 scopus 로고    scopus 로고
    • Inhibition of proinflammatory genes in anti-GBM glomerulonephritis by targeted dexamethasone-loaded Ab Esel liposomes
    • Asgeirsdóttir SA, Zwiers PJ, Morselt HW, et al. Inhibition of proinflammatory genes in anti-GBM glomerulonephritis by targeted dexamethasone-loaded Ab Esel liposomes. Am J Physiol Renal Physiol. 2008;294(3):554-561.
    • (2008) Am J Physiol Renal Physiol , vol.294 , Issue.3 , pp. 554-561
    • Asgeirsdóttir, S.A.1    Zwiers, P.J.2    Morselt, H.W.3
  • 51
    • 3042795227 scopus 로고    scopus 로고
    • Effect of antisense TGF-beta1 oligodeoxynucleotides in streptozotocin-induced diabetic rat kidney
    • Jeong HS, Park KK, Kim SP, Choi IJ, Lee IK, Kim HC. Effect of antisense TGF-beta1 oligodeoxynucleotides in streptozotocin induced diabetic rat kidney. J Korean Med Sci. 2004;19(3):374-383. (Pubitemid 38859827)
    • (2004) Journal of Korean Medical Science , vol.19 , Issue.3 , pp. 374-383
    • Jeong, H.S.1    Park, K.K.2    Kim, S.P.3    Choi, I.J.4    Lee, I.K.5    Kim, H.C.6
  • 52
    • 38649130217 scopus 로고    scopus 로고
    • Suppression of mesangial cell proliferation and extracellular matrix production in streptozotocin-induced diabetic rats by Sp1 decoy oligodeoxynucleotide in vitro and in vivo
    • Kang JH, Chae YM, Park KK, Kim CH, Lee IS, Chang YC. Suppression of mesangial cell proliferation and extracellular matrix production in streptozotocin-induced diabetic rats by Sp1 decoy oligodeoxynucleotide in vitro and in vivo. J Cell Biochem. 2008;103(2):663-674.
    • (2008) J Cell Biochem , vol.103 , Issue.2 , pp. 663-674
    • Kang, J.H.1    Chae, Y.M.2    Park, K.K.3    Kim, C.H.4    Lee, I.S.5    Chang, Y.C.6
  • 53
    • 0026658044 scopus 로고
    • Direct in vivo gene introduction into rat kidney
    • Tomita N, Higaki J, Morishita R, et al. Direct in vivo gene introduction into rat kidney. Biochem Biophys Res Commun. 1992;186(1):129-134.
    • (1992) Biochem Biophys Res Commun , vol.186 , Issue.1 , pp. 129-134
    • Tomita, N.1    Higaki, J.2    Morishita, R.3
  • 55
    • 78649447461 scopus 로고    scopus 로고
    • Mesangial pathology in glomerular disease: Targets for therapeutic intervention
    • Scindia YM, Deshmukh US, Bagavant H. Mesangial pathology in glomerular disease: targets for therapeutic intervention. Adv Drug Deliv Rev. 2010;62(14):1337-1343.
    • (2010) Adv Drug Deliv Rev , vol.62 , Issue.14 , pp. 1337-1343
    • Scindia, Y.M.1    Deshmukh, U.S.2    Bagavant, H.3
  • 56
    • 33644873618 scopus 로고    scopus 로고
    • Immunoliposome targeting to mesangial cells: A promising strategy for specific drug delivery to the kidney
    • DOI 10.1681/ASN.2005050485
    • Tuffin G, Waelti E, Huwyler J, Hammer C, Marti HP. Immunoliposome targeting to mesangial cells: a promising strategy for specific drug delivery to the kidney. J Am Soc Nephrol. 2005;16(11):3295-3305. (Pubitemid 46179334)
    • (2005) Journal of the American Society of Nephrology , vol.16 , Issue.11 , pp. 3295-3305
    • Tuffin, G.1    Waelti, E.2    Huwyler, J.3    Hammer, C.4    Marti, H.-P.5
  • 57
    • 57349198768 scopus 로고    scopus 로고
    • Anti-α8 integrin immunoliposomes in glomeruli of lupus-susceptible mice: A novel system for delivery of therapeutic agents to the renal glomerulus in systemic lupus erythematosus
    • Scindia Y, Deshmukh U, Thimmalapura PR, Bagavant H. Anti-α8 integrin immunoliposomes in glomeruli of lupus-susceptible mice: a novel system for delivery of therapeutic agents to the renal glomerulus in systemic lupus erythematosus. Arthritis Rheum. 2008;58(12):3884-3891.
    • (2008) Arthritis Rheum , vol.58 , Issue.12 , pp. 3884-3891
    • Scindia, Y.1    Deshmukh, U.2    Thimmalapura, P.R.3    Bagavant, H.4
  • 58
    • 0028939758 scopus 로고
    • Sequence and tissue distribution of the human integrin alpha subunit: Beta1-associated alpha subunit expressed in smooth muscle cells
    • Schnapp LM, Breuss JM, Ramos DM, Sheppard D, Pytela R. Sequence and tissue distribution of the human integrin alpha subunit: beta1-associated alpha subunit expressed in smooth muscle cells. J Cell Sci. 1995;108(2):537-544.
    • (1995) J Cell Sci , vol.108 , Issue.2 , pp. 537-544
    • Schnapp, L.M.1    Breuss, J.M.2    Ramos, D.M.3    Sheppard, D.4    Pytela, R.5
  • 59
    • 79951768357 scopus 로고    scopus 로고
    • Role of T cell mediated inflammation in lupus-like glomerulonephritis (GN)
    • AAI abstract 93.40
    • Bagavant H, Scindia Y, Nandula S, Deshmukh U. Role of T cell mediated inflammation in lupus-like glomerulonephritis (GN) [AAI abstract 93.40]. J Immunol. 2010;184:93.40.
    • (2010) J Immunol , vol.184
    • Bagavant, H.1    Scindia, Y.2    Nandula, S.3    Deshmukh, U.4


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